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The map label for this gene is crt [H]

Identifier: 170750181

GI number: 170750181

Start: 4023252

End: 4024313

Strand: Reverse

Name: crt [H]

Synonym: Mrad2831_3783

Alternate gene names: 170750181

Gene position: 4024313-4023252 (Counterclockwise)

Preceding gene: 170750182

Following gene: 170750180

Centisome position: 66.21

GC content: 72.79

Gene sequence:

>1062_bases
ATGAGCGACGTGATCGTCGAGCGGGTCGGCGCGCTGGGGCGCCTTCGGCTCAACCGGCCGAAGGCCCTGAACGCCTTGAC
GCATGGCATGGTGGGCGAGATCGACCGGGCGCTCGACCAGTTCTCGGCGGATCCCGGAATCGCCGCGGTGCTGCTCACCG
GCGAGGGCGAGCGCGGCCTCTGCGCCGGCGGCGACCTGCGCTCCCTCTACGACAATCCCGGCACCGCCTTCGCCGAGACC
TTCTGGCGCGACGAGTACAGGCTCGATTCCCGCATCGCCGCCTACGAGAAGCCGTTCGTGGCGGTGATGGACGGCATCAC
CATGGGCGGGGGTGTCGGGCTCGCGGGCCACGCATCGCACCGGATCGTCACCGAGCGCTCCCGCGTCGCCATGCCGGAAA
CCGGCATCGGCTACCTGCCGGATGTCGGCGGGACGTGGCTGCTGCCGCGCGCGCCCGGCGAGATCGGCACCTATCTCGGC
CTGACCGGCGAGCCGGTCGGCGCCGCCGACGCGATCTTCTGCCGCCTGGCCGACGTCATGGTCCCGTCCGCGAGGCTGCC
CAACCTCATCGACGACCTCCTGGCGCTCGATCCGGATGCCGGGCAGGAGGGCGTGCGGGACGTGATCGCCCGGTCCGCGC
AGGACGCCGGCCCGGCGCCCCTGGTCGCGCACCGCGCGGTGATCGACCGCTGCTTTTCCTTCGACATGGTCGACGAGATC
CTCTCGGCCCTCGAGGCGGACGGCTCCGACTTCGCCGCCACGACCCGGGCAACGCTGTTGACCAAGGCGCCGTCGAGCCT
CGTCCTGACGCTGTGCCTCCTGCGCCTCGGCCGCGGCGCGCCGAACCTGGAGGCCTGCCTGGAGCGCGAGTTCCACGCCT
CGCTGGCGCTGCTGGCGGAGGGCGACTTCCGCGAGGGCATCCGCGCCGCGGTGATCGACAAGGACAAGAGCCCGCGCTGG
ACCCCGCCGACCCTCGACGCGGTCGACCCGGCGCGGATCGCCCGCTGGCTGGAGAAGCGGGCGGCGCCGGTTTTTTCGGA
CGCGCGCACGGGGCCGGTGTGA

Upstream 100 bases:

>100_bases
TGGAGAAGATCGTCCGGGACCTGCGCGTGCACCAGATCCTCGAAGGGACCAACGAGATCATGCGGCTGATCATCGCCCGC
GGGCTGACCGGGGGGCGCCG

Downstream 100 bases:

>100_bases
TGACGCGTCGCACGTTCCCACCCAGACCCTCGTCCTGAGCCGACGAAGCGTAGGCTTCGAAGGAGGGCTCCAGGAGCCGC
TGTGATCCCTGGAGCCCTCC

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSDVIVERVGALGRLRLNRPKALNALTHGMVGEIDRALDQFSADPGIAAVLLTGEGERGLCAGGDLRSLYDNPGTAFAET
FWRDEYRLDSRIAAYEKPFVAVMDGITMGGGVGLAGHASHRIVTERSRVAMPETGIGYLPDVGGTWLLPRAPGEIGTYLG
LTGEPVGAADAIFCRLADVMVPSARLPNLIDDLLALDPDAGQEGVRDVIARSAQDAGPAPLVAHRAVIDRCFSFDMVDEI
LSALEADGSDFAATTRATLLTKAPSSLVLTLCLLRLGRGAPNLEACLEREFHASLALLAEGDFREGIRAAVIDKDKSPRW
TPPTLDAVDPARIARWLEKRAAPVFSDARTGPV

Sequences:

>Translated_353_residues
MSDVIVERVGALGRLRLNRPKALNALTHGMVGEIDRALDQFSADPGIAAVLLTGEGERGLCAGGDLRSLYDNPGTAFAET
FWRDEYRLDSRIAAYEKPFVAVMDGITMGGGVGLAGHASHRIVTERSRVAMPETGIGYLPDVGGTWLLPRAPGEIGTYLG
LTGEPVGAADAIFCRLADVMVPSARLPNLIDDLLALDPDAGQEGVRDVIARSAQDAGPAPLVAHRAVIDRCFSFDMVDEI
LSALEADGSDFAATTRATLLTKAPSSLVLTLCLLRLGRGAPNLEACLEREFHASLALLAEGDFREGIRAAVIDKDKSPRW
TPPTLDAVDPARIARWLEKRAAPVFSDARTGPV
>Mature_352_residues
SDVIVERVGALGRLRLNRPKALNALTHGMVGEIDRALDQFSADPGIAAVLLTGEGERGLCAGGDLRSLYDNPGTAFAETF
WRDEYRLDSRIAAYEKPFVAVMDGITMGGGVGLAGHASHRIVTERSRVAMPETGIGYLPDVGGTWLLPRAPGEIGTYLGL
TGEPVGAADAIFCRLADVMVPSARLPNLIDDLLALDPDAGQEGVRDVIARSAQDAGPAPLVAHRAVIDRCFSFDMVDEIL
SALEADGSDFAATTRATLLTKAPSSLVLTLCLLRLGRGAPNLEACLEREFHASLALLAEGDFREGIRAAVIDKDKSPRWT
PPTLDAVDPARIARWLEKRAAPVFSDARTGPV

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=333, Percent_Identity=38.7387387387387, Blast_Score=231, Evalue=7e-61,
Organism=Homo sapiens, GI37594469, Length=303, Percent_Identity=37.2937293729373, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI194097323, Length=187, Percent_Identity=33.1550802139037, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI68989263, Length=317, Percent_Identity=26.813880126183, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1787659, Length=184, Percent_Identity=30.9782608695652, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI221142681, Length=180, Percent_Identity=30.5555555555556, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787660, Length=164, Percent_Identity=35.3658536585366, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25144160, Length=344, Percent_Identity=36.3372093023256, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI25144157, Length=344, Percent_Identity=36.3372093023256, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17554946, Length=172, Percent_Identity=33.7209302325581, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25145438, Length=187, Percent_Identity=28.8770053475936, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17508951, Length=149, Percent_Identity=30.8724832214765, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25144276, Length=149, Percent_Identity=30.8724832214765, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=149, Percent_Identity=30.8724832214765, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17540714, Length=178, Percent_Identity=26.9662921348315, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17558304, Length=242, Percent_Identity=21.900826446281, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=342, Percent_Identity=33.9181286549708, Blast_Score=169, Evalue=7e-43,
Organism=Drosophila melanogaster, GI28571730, Length=339, Percent_Identity=37.7581120943953, Blast_Score=227, Evalue=8e-60,
Organism=Drosophila melanogaster, GI28571729, Length=339, Percent_Identity=37.7581120943953, Blast_Score=227, Evalue=8e-60,
Organism=Drosophila melanogaster, GI20129971, Length=176, Percent_Identity=34.0909090909091, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24653477, Length=176, Percent_Identity=34.0909090909091, Blast_Score=102, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 37575; Mature: 37444

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVIVERVGALGRLRLNRPKALNALTHGMVGEIDRALDQFSADPGIAAVLLTGEGERGL
CCHHHHHHHCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCC
CAGGDLRSLYDNPGTAFAETFWRDEYRLDSRIAAYEKPFVAVMDGITMGGGVGLAGHASH
CCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEECCCCCCCCCCCC
RIVTERSRVAMPETGIGYLPDVGGTWLLPRAPGEIGTYLGLTGEPVGAADAIFCRLADVM
CEEECHHHCCCCCCCCCCCCCCCCCEECCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHH
VPSARLPNLIDDLLALDPDAGQEGVRDVIARSAQDAGPAPLVAHRAVIDRCFSFDMVDEI
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LSALEADGSDFAATTRATLLTKAPSSLVLTLCLLRLGRGAPNLEACLEREFHASLALLAE
HHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEC
GDFREGIRAAVIDKDKSPRWTPPTLDAVDPARIARWLEKRAAPVFSDARTGPV
CCHHHCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SDVIVERVGALGRLRLNRPKALNALTHGMVGEIDRALDQFSADPGIAAVLLTGEGERGL
CHHHHHHHCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCC
CAGGDLRSLYDNPGTAFAETFWRDEYRLDSRIAAYEKPFVAVMDGITMGGGVGLAGHASH
CCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCEECCCCCCCCCCCC
RIVTERSRVAMPETGIGYLPDVGGTWLLPRAPGEIGTYLGLTGEPVGAADAIFCRLADVM
CEEECHHHCCCCCCCCCCCCCCCCCEECCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHH
VPSARLPNLIDDLLALDPDAGQEGVRDVIARSAQDAGPAPLVAHRAVIDRCFSFDMVDEI
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LSALEADGSDFAATTRATLLTKAPSSLVLTLCLLRLGRGAPNLEACLEREFHASLALLAE
HHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEC
GDFREGIRAAVIDKDKSPRWTPPTLDAVDPARIARWLEKRAAPVFSDARTGPV
CCHHHCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]