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The map label for this gene is pdxJ [H]

Identifier: 170749858

GI number: 170749858

Start: 3672122

End: 3672871

Strand: Reverse

Name: pdxJ [H]

Synonym: Mrad2831_3458

Alternate gene names: 170749858

Gene position: 3672871-3672122 (Counterclockwise)

Preceding gene: 229597237

Following gene: 170749857

Centisome position: 60.43

GC content: 74.93

Gene sequence:

>750_bases
ATGACCTCCGAGAAACTGCGCCTGGGCGTCAACATCGATCACGTCGCGACCGTCCGCAACGCCCGCGGCGGCGACTACCC
GGACCCGGTGCGCGCGGCCCTGCTCGCCGTCGAGGCGGGCGCCGACGGGATCACCGCGCATCTCCGCGAGGACCGGCGCC
ACATCCGCGACACCGACATCGCGGCGCTCAAGCGCGGCCTGTCCGTGCCGCTCAACTTCGAGATGGCCGCCACCGACGAG
ATGGTGGCGATCGCGCTGGACACCCGCCCGCACGCCGCCTGCCTCGTCCCGGAGAAGCGCGAGGAGCGCACCACCGAGGG
CGGCCTCGACATCGTCGGCGGCCGGGAGCACCTGGCGCCGCGCATCCGGGCCCTCGCGGAGGCCGGCATCCGCGTCTCGC
TGTTCGTCGAGCCCGAGCCCGCGATCATGGACGCCGCCCGCGCCCTCGGGGCGCCGGTGGTCGAGCTGCACACCGGCAGC
TACTGCGAGGCGGCTCTGGAGGACGACGACGCCCGGACCGCGCGCGAGCTCGCCCGCATCCGGCGCGCGGCGGAGCACGG
CGACGGCCTCGGCCTCGAGATCCACGCGGGCCACGGGCTCACCCTCGGCAGCGTCGGCCCGGTGGCGGCCCTGCCGCAGA
TCCGGGAGCTGAACATCGGCCATTCCCTGATCGCCGACGCGATCTTCGTGGGACTCGACCGGGCGGTGCGCGACATGCGG
GCCGCCATGGACCGGGCGCGGCACCCATGA

Upstream 100 bases:

>100_bases
GATCCTCCGCATACCGCGGCACGGGGTGAGGGCGCGCCGCGCCCTCCGGACCCCGCCGGTATGCCTGTCGCACCGCGCCG
ACACGGGGACGAACGAGCGG

Downstream 100 bases:

>100_bases
TCGTCGGGATCGGCTCGGATCTCTGCGACATCCGCCGGATCGCCCGGACCCTGGAGCGGCACGGCGCGCGCTTCACCCAC
CGGGTCTTCACCGACGGGGA

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTSEKLRLGVNIDHVATVRNARGGDYPDPVRAALLAVEAGADGITAHLREDRRHIRDTDIAALKRGLSVPLNFEMAATDE
MVAIALDTRPHAACLVPEKREERTTEGGLDIVGGREHLAPRIRALAEAGIRVSLFVEPEPAIMDAARALGAPVVELHTGS
YCEAALEDDDARTARELARIRRAAEHGDGLGLEIHAGHGLTLGSVGPVAALPQIRELNIGHSLIADAIFVGLDRAVRDMR
AAMDRARHP

Sequences:

>Translated_249_residues
MTSEKLRLGVNIDHVATVRNARGGDYPDPVRAALLAVEAGADGITAHLREDRRHIRDTDIAALKRGLSVPLNFEMAATDE
MVAIALDTRPHAACLVPEKREERTTEGGLDIVGGREHLAPRIRALAEAGIRVSLFVEPEPAIMDAARALGAPVVELHTGS
YCEAALEDDDARTARELARIRRAAEHGDGLGLEIHAGHGLTLGSVGPVAALPQIRELNIGHSLIADAIFVGLDRAVRDMR
AAMDRARHP
>Mature_248_residues
TSEKLRLGVNIDHVATVRNARGGDYPDPVRAALLAVEAGADGITAHLREDRRHIRDTDIAALKRGLSVPLNFEMAATDEM
VAIALDTRPHAACLVPEKREERTTEGGLDIVGGREHLAPRIRALAEAGIRVSLFVEPEPAIMDAARALGAPVVELHTGSY
CEAALEDDDARTARELARIRRAAEHGDGLGLEIHAGHGLTLGSVGPVAALPQIRELNIGHSLIADAIFVGLDRAVRDMRA
AMDRARHP

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate [H]

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788917, Length=243, Percent_Identity=54.320987654321, Blast_Score=262, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR004569 [H]

Pfam domain/function: PF03740 PdxJ [H]

EC number: =2.6.99.2 [H]

Molecular weight: Translated: 26694; Mature: 26563

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSEKLRLGVNIDHVATVRNARGGDYPDPVRAALLAVEAGADGITAHLREDRRHIRDTDI
CCCCCEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHH
AALKRGLSVPLNFEMAATDEMVAIALDTRPHAACLVPEKREERTTEGGLDIVGGREHLAP
HHHHHCCCCCCCEEEECCCCEEEEEECCCCCEEEECCCHHHHCCCCCCCEEECCHHHHHH
RIRALAEAGIRVSLFVEPEPAIMDAARALGAPVVELHTGSYCEAALEDDDARTARELARI
HHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCEEEECCCCHHHHHCCCCHHHHHHHHHHH
RRAAEHGDGLGLEIHAGHGLTLGSVGPVAALPQIRELNIGHSLIADAIFVGLDRAVRDMR
HHHHHCCCCCEEEEECCCCEEECCCCCHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
AAMDRARHP
HHHHHHCCC
>Mature Secondary Structure 
TSEKLRLGVNIDHVATVRNARGGDYPDPVRAALLAVEAGADGITAHLREDRRHIRDTDI
CCCCEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHH
AALKRGLSVPLNFEMAATDEMVAIALDTRPHAACLVPEKREERTTEGGLDIVGGREHLAP
HHHHHCCCCCCCEEEECCCCEEEEEECCCCCEEEECCCHHHHCCCCCCCEEECCHHHHHH
RIRALAEAGIRVSLFVEPEPAIMDAARALGAPVVELHTGSYCEAALEDDDARTARELARI
HHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCEEEECCCCHHHHHCCCCHHHHHHHHHHH
RRAAEHGDGLGLEIHAGHGLTLGSVGPVAALPQIRELNIGHSLIADAIFVGLDRAVRDMR
HHHHHCCCCCEEEEECCCCEEECCCCCHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
AAMDRARHP
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA