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The map label for this gene is acpS

Identifier: 170749857

GI number: 170749857

Start: 3671715

End: 3672125

Strand: Reverse

Name: acpS

Synonym: Mrad2831_3457

Alternate gene names: 170749857

Gene position: 3672125-3671715 (Counterclockwise)

Preceding gene: 170749858

Following gene: 170749856

Centisome position: 60.42

GC content: 74.94

Gene sequence:

>411_bases
ATGATCGTCGGGATCGGCTCGGATCTCTGCGACATCCGCCGGATCGCCCGGACCCTGGAGCGGCACGGCGCGCGCTTCAC
CCACCGGGTCTTCACCGACGGGGAGCGGGCCCGCTGCGACCGGCGGGCCGCCCGCGCCGAGGGCTACGCCCGCCGCTTCG
CCGCCAAGGAAGCCTGCGCCAAGGCGCTCGGCACCGGCCTCAGCGCCGGCGTCTTCTGGCGCGACATGGAGGTGGTGAAC
CTGCCCTCCGGCCAGCCGACCCTGCGGCTCGCGGGCGGCGCGGCGGAGCGGCTCGCGGAACTGCTGCCGGCGGGGCACGC
GGCGCGCCTGCACGTGAGCCTCACGGACGATCCGCCGATGGCGCAGGCCTTCGTGATCATCGAGGCCTTGCCGGTCTCTG
TCGCCGGTTGA

Upstream 100 bases:

>100_bases
AGCTGAACATCGGCCATTCCCTGATCGCCGACGCGATCTTCGTGGGACTCGACCGGGCGGTGCGCGACATGCGGGCCGCC
ATGGACCGGGCGCGGCACCC

Downstream 100 bases:

>100_bases
GGCCGGCGTCGCGGATTAGCCAGCGGCGGTCGCGCGTTGCGGGGGGCTCGCGCATGGTCTAGACCGCCGGTCACGGCGGA
CACGATTGCGGCGCATTCCT

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MIVGIGSDLCDIRRIARTLERHGARFTHRVFTDGERARCDRRAARAEGYARRFAAKEACAKALGTGLSAGVFWRDMEVVN
LPSGQPTLRLAGGAAERLAELLPAGHAARLHVSLTDDPPMAQAFVIIEALPVSVAG

Sequences:

>Translated_136_residues
MIVGIGSDLCDIRRIARTLERHGARFTHRVFTDGERARCDRRAARAEGYARRFAAKEACAKALGTGLSAGVFWRDMEVVN
LPSGQPTLRLAGGAAERLAELLPAGHAARLHVSLTDDPPMAQAFVIIEALPVSVAG
>Mature_136_residues
MIVGIGSDLCDIRRIARTLERHGARFTHRVFTDGERARCDRRAARAEGYARRFAAKEACAKALGTGLSAGVFWRDMEVVN
LPSGQPTLRLAGGAAERLAELLPAGHAARLHVSLTDDPPMAQAFVIIEALPVSVAG

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=128, Percent_Identity=42.1875, Blast_Score=83, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_METRJ (B1LTR5)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001756117.1
- ProteinModelPortal:   B1LTR5
- SMR:   B1LTR5
- GeneID:   6139505
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_3457
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- ProtClustDB:   PRK00070
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14590; Mature: 14590

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGIGSDLCDIRRIARTLERHGARFTHRVFTDGERARCDRRAARAEGYARRFAAKEACA
CEEECCCCHHHHHHHHHHHHHCCCCEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGLSAGVFWRDMEVVNLPSGQPTLRLAGGAAERLAELLPAGHAARLHVSLTDDPPM
HHHCCCCCCCEEEECEEEEECCCCCCEEEECCCHHHHHHHHCCCCCCEEEEEEECCCCCH
AQAFVIIEALPVSVAG
HHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIVGIGSDLCDIRRIARTLERHGARFTHRVFTDGERARCDRRAARAEGYARRFAAKEACA
CEEECCCCHHHHHHHHHHHHHCCCCEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGLSAGVFWRDMEVVNLPSGQPTLRLAGGAAERLAELLPAGHAARLHVSLTDDPPM
HHHCCCCCCCEEEECEEEEECCCCCCEEEECCCHHHHHHHHCCCCCCEEEEEEECCCCCH
AQAFVIIEALPVSVAG
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA