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The map label for this gene is moaC [H]

Identifier: 170749503

GI number: 170749503

Start: 3276461

End: 3276952

Strand: Reverse

Name: moaC [H]

Synonym: Mrad2831_3098

Alternate gene names: 170749503

Gene position: 3276952-3276461 (Counterclockwise)

Preceding gene: 170749504

Following gene: 170749502

Centisome position: 53.92

GC content: 71.75

Gene sequence:

>492_bases
ATGCGGCCGGGCTCGACGCTGACCCATCTCGACACCAGCGGCGCGGCCAACATGGTCGACGTCACCGACAAGCCCGCCAC
CGACCGGACCGCCCGGGCGGAAGGCCAGATCGTGATGAGGCCCGAGACGCTGGCGCTGATCCGCGAGGGCGACGCCAAGA
AGGGCGACGTGATCGGCACGGCCCGGCTCGCCGGCATCATGGCGGCCAAGCGCACCCACGAGCTGATCCCGCTCTGTCAC
CCGCTCCTGCTGTCGAACGTGCGGGTCGAGTGCGAGCCCGACGACGCGCTCCCGGGCCTGCGCATCGCCGCCGAGGTCCG
TGTCCAGGGCCCGACCGGCGTCGAGATGGAGGCGCTCACCGCCGTCTCGGTGGCCTGCCTGACGGTCTACGACATGGTGA
AGGCGGTCGATCGCGGCATGCGGATCGAGGGGATCCGGCTGACCGCAAAGGATGGCGGCCGCTCGGGCGCCTACCGGGCA
CCGGCGGAATGA

Upstream 100 bases:

>100_bases
GAGCCTGATGCGGCAGCCGGACGTCGCGGCAGCGGCCCGCGCCCTGCTGTTCGGCGACGCGGGGGCCACGGGCGGCAAGC
CGCGGAAGAAGGCGTAAGGC

Downstream 100 bases:

>100_bases
GCGGCCTGATCCCGGTCGCGGAGGCGCTGGCCCGGGTGCTCGCGAGCGTCGCCGCGCCGGTCGAGGCCGAGACCGTCCCG
CTGGCTCGGGCCGGCGGCCG

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MRPGSTLTHLDTSGAANMVDVTDKPATDRTARAEGQIVMRPETLALIREGDAKKGDVIGTARLAGIMAAKRTHELIPLCH
PLLLSNVRVECEPDDALPGLRIAAEVRVQGPTGVEMEALTAVSVACLTVYDMVKAVDRGMRIEGIRLTAKDGGRSGAYRA
PAE

Sequences:

>Translated_163_residues
MRPGSTLTHLDTSGAANMVDVTDKPATDRTARAEGQIVMRPETLALIREGDAKKGDVIGTARLAGIMAAKRTHELIPLCH
PLLLSNVRVECEPDDALPGLRIAAEVRVQGPTGVEMEALTAVSVACLTVYDMVKAVDRGMRIEGIRLTAKDGGRSGAYRA
PAE
>Mature_163_residues
MRPGSTLTHLDTSGAANMVDVTDKPATDRTARAEGQIVMRPETLALIREGDAKKGDVIGTARLAGIMAAKRTHELIPLCH
PLLLSNVRVECEPDDALPGLRIAAEVRVQGPTGVEMEALTAVSVACLTVYDMVKAVDRGMRIEGIRLTAKDGGRSGAYRA
PAE

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=159, Percent_Identity=55.3459119496855, Blast_Score=167, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=44.9664429530201, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28574490, Length=158, Percent_Identity=51.2658227848101, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28574492, Length=142, Percent_Identity=51.4084507042254, Blast_Score=132, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17300; Mature: 17300

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPGSTLTHLDTSGAANMVDVTDKPATDRTARAEGQIVMRPETLALIREGDAKKGDVIGT
CCCCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCEEEH
ARLAGIMAAKRTHELIPLCHPLLLSNVRVECEPDDALPGLRIAAEVRVQGPTGVEMEALT
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEEEECCCCCCCHHHHH
AVSVACLTVYDMVKAVDRGMRIEGIRLTAKDGGRSGAYRAPAE
HHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MRPGSTLTHLDTSGAANMVDVTDKPATDRTARAEGQIVMRPETLALIREGDAKKGDVIGT
CCCCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCEEEH
ARLAGIMAAKRTHELIPLCHPLLLSNVRVECEPDDALPGLRIAAEVRVQGPTGVEMEALT
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEEEECCCCCCCHHHHH
AVSVACLTVYDMVKAVDRGMRIEGIRLTAKDGGRSGAYRAPAE
HHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA