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The map label for this gene is yggW [H]

Identifier: 170749348

GI number: 170749348

Start: 3099945

End: 3101120

Strand: Reverse

Name: yggW [H]

Synonym: Mrad2831_2941

Alternate gene names: 170749348

Gene position: 3101120-3099945 (Counterclockwise)

Preceding gene: 170749349

Following gene: 170749346

Centisome position: 51.02

GC content: 74.15

Gene sequence:

>1176_bases
ATGTCATCGACCGGCCCGGACCATCCGACCCGCGACGCGGGCTTCGGGATCTACCTGCACTGGCCCTTCTGCGCCGCGAA
GTGCCCGTACTGCGACTTCAACAGCCACGTCCGCCGCGCGGGCGTGGACGAGCCCCGCTTCCTCGCCGCCTTCCGCGCCG
AGATCGCCCACAATGCCGCCCGCACGCCGGGCCGCACCGTCACCAGCATCTTCCTCGGCGGCGGCACGCCCTCGCTGATG
CAGCCCGCGACCGTGGCCGGCCTGCTCGACGCGGTCGCGGCCCACTGGGCGGTCGCGCCGGACGCGGAAGTGACCCTCGA
GGCCAACCCGTCGAGTGTCGAGGCCGGCCGCTTCCACGGCTACCGCGCGGCCGGGGTCAACCGTGTGTCGCTCGGCATCC
AGGCCCTCGACGATGCCTCGCTGCGGACCCTGGGGCGCCTGCACGACACGGCACAGGCCCTGGACGCGATCGCCCTGGCG
CAGTCGGCCTTCGCGCGGACCTCCTTCGACCTGATCTACGCGCGGCCCGGCCAGACGCCGGCGCTGTGGCGGGCGGAGCT
CGCCGAGGCGCTCGCGCGGGCCGCGGAGCACCTCTCGCTCTACCAGCTCACCATCGAGCCCGGGACACCGTTCCACGGGC
TCGCCGCCGCCGGCAAGCTGGTGACGCCGGACGACGAGGTCGGCCGCGCCCTCTACGACGTCACCCAGGATCTCTGCGCG
AGGGCCGGCCTTCCGGCCTACGAGATCTCGAACCACGCGCGGCCCGGCGCCGAATCGCGGCACAACCTGCTCTACTGGCG
CTACGGCGAGTACGCCGGCATCGGTCCGGGCGCCCACGGGCGGCTCGTGACGCCCGGGGGCCGGCTCGGAACCGTGACGG
AGCGATCGCCCGAGGCGTGGCTCGCCCGGGTCGAGGCCGAGGGCCACGGGATCGTCGAGACCGAGATCCTCACCGCAGCC
GATCAGGCCGACGAGTTCCTGGTGATGGGCCTGCGCCTGCGCGAGGGGATCGATCCCGACACCTACGCGGCCCTCAAGGG
ACGGCCGCTGAACGGCAACCGGATCGGCATGCTGATCGGGGACGGCCTGCTGGAGCGGCTGCCCGGCGGCCGCATCGCCG
CCACGGCGCGGGGCGCGCCGGTGCTGAACGCGCTGGTCGCCGAACTCGCCGCCTGA

Upstream 100 bases:

>100_bases
GTCCCACCGCGCCCGCGCCTTCGTCGAGCTGAGCCGCGCCTGCCTCGCGCCCGGCGCCTGATTTGCCAAACGGGGCGCGG
GCGCTCACATCCCCGCCATC

Downstream 100 bases:

>100_bases
TCAGATCGCGGGCTTCGCGAGGACCCGGGGCGCGGGGCTGACGGGCGTCGCGGCGTTGTTGCGGATCTCGTAGACCGCGA
GGGACCGGTCGCTCTGACCG

Product: oxygen-independent coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSSTGPDHPTRDAGFGIYLHWPFCAAKCPYCDFNSHVRRAGVDEPRFLAAFRAEIAHNAARTPGRTVTSIFLGGGTPSLM
QPATVAGLLDAVAAHWAVAPDAEVTLEANPSSVEAGRFHGYRAAGVNRVSLGIQALDDASLRTLGRLHDTAQALDAIALA
QSAFARTSFDLIYARPGQTPALWRAELAEALARAAEHLSLYQLTIEPGTPFHGLAAAGKLVTPDDEVGRALYDVTQDLCA
RAGLPAYEISNHARPGAESRHNLLYWRYGEYAGIGPGAHGRLVTPGGRLGTVTERSPEAWLARVEAEGHGIVETEILTAA
DQADEFLVMGLRLREGIDPDTYAALKGRPLNGNRIGMLIGDGLLERLPGGRIAATARGAPVLNALVAELAA

Sequences:

>Translated_391_residues
MSSTGPDHPTRDAGFGIYLHWPFCAAKCPYCDFNSHVRRAGVDEPRFLAAFRAEIAHNAARTPGRTVTSIFLGGGTPSLM
QPATVAGLLDAVAAHWAVAPDAEVTLEANPSSVEAGRFHGYRAAGVNRVSLGIQALDDASLRTLGRLHDTAQALDAIALA
QSAFARTSFDLIYARPGQTPALWRAELAEALARAAEHLSLYQLTIEPGTPFHGLAAAGKLVTPDDEVGRALYDVTQDLCA
RAGLPAYEISNHARPGAESRHNLLYWRYGEYAGIGPGAHGRLVTPGGRLGTVTERSPEAWLARVEAEGHGIVETEILTAA
DQADEFLVMGLRLREGIDPDTYAALKGRPLNGNRIGMLIGDGLLERLPGGRIAATARGAPVLNALVAELAA
>Mature_390_residues
SSTGPDHPTRDAGFGIYLHWPFCAAKCPYCDFNSHVRRAGVDEPRFLAAFRAEIAHNAARTPGRTVTSIFLGGGTPSLMQ
PATVAGLLDAVAAHWAVAPDAEVTLEANPSSVEAGRFHGYRAAGVNRVSLGIQALDDASLRTLGRLHDTAQALDAIALAQ
SAFARTSFDLIYARPGQTPALWRAELAEALARAAEHLSLYQLTIEPGTPFHGLAAAGKLVTPDDEVGRALYDVTQDLCAR
AGLPAYEISNHARPGAESRHNLLYWRYGEYAGIGPGAHGRLVTPGGRLGTVTERSPEAWLARVEAEGHGIVETEILTAAD
QADEFLVMGLRLREGIDPDTYAALKGRPLNGNRIGMLIGDGLLERLPGGRIAATARGAPVLNALVAELAA

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=300, Percent_Identity=42.3333333333333, Blast_Score=226, Evalue=3e-59,
Organism=Escherichia coli, GI1789325, Length=323, Percent_Identity=39.938080495356, Blast_Score=231, Evalue=7e-62,
Organism=Escherichia coli, GI87082341, Length=318, Percent_Identity=25.4716981132075, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 41441; Mature: 41310

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTGPDHPTRDAGFGIYLHWPFCAAKCPYCDFNSHVRRAGVDEPRFLAAFRAEIAHNAA
CCCCCCCCCCCCCCEEEEEECCHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHC
RTPGRTVTSIFLGGGTPSLMQPATVAGLLDAVAAHWAVAPDAEVTLEANPSSVEAGRFHG
CCCCCEEEEEEECCCCCHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCC
YRAAGVNRVSLGIQALDDASLRTLGRLHDTAQALDAIALAQSAFARTSFDLIYARPGQTP
EECCCCCEEEECHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCH
ALWRAELAEALARAAEHLSLYQLTIEPGTPFHGLAAAGKLVTPDDEVGRALYDVTQDLCA
HHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
RAGLPAYEISNHARPGAESRHNLLYWRYGEYAGIGPGAHGRLVTPGGRLGTVTERSPEAW
HCCCCHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHH
LARVEAEGHGIVETEILTAADQADEFLVMGLRLREGIDPDTYAALKGRPLNGNRIGMLIG
EEEEECCCCCEEEHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEEEEC
DGLLERLPGGRIAATARGAPVLNALVAELAA
CHHHHHCCCCCEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SSTGPDHPTRDAGFGIYLHWPFCAAKCPYCDFNSHVRRAGVDEPRFLAAFRAEIAHNAA
CCCCCCCCCCCCCEEEEEECCHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHC
RTPGRTVTSIFLGGGTPSLMQPATVAGLLDAVAAHWAVAPDAEVTLEANPSSVEAGRFHG
CCCCCEEEEEEECCCCCHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCC
YRAAGVNRVSLGIQALDDASLRTLGRLHDTAQALDAIALAQSAFARTSFDLIYARPGQTP
EECCCCCEEEECHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCH
ALWRAELAEALARAAEHLSLYQLTIEPGTPFHGLAAAGKLVTPDDEVGRALYDVTQDLCA
HHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
RAGLPAYEISNHARPGAESRHNLLYWRYGEYAGIGPGAHGRLVTPGGRLGTVTERSPEAW
HCCCCHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHH
LARVEAEGHGIVETEILTAADQADEFLVMGLRLREGIDPDTYAALKGRPLNGNRIGMLIG
EEEEECCCCCEEEHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEEEEC
DGLLERLPGGRIAATARGAPVLNALVAELAA
CHHHHHCCCCCEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]