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The map label for this gene is yggV [C]

Identifier: 170749349

GI number: 170749349

Start: 3101160

End: 3101789

Strand: Reverse

Name: yggV [C]

Synonym: Mrad2831_2942

Alternate gene names: 170749349

Gene position: 3101789-3101160 (Counterclockwise)

Preceding gene: 170749350

Following gene: 170749348

Centisome position: 51.03

GC content: 73.33

Gene sequence:

>630_bases
GTGAGCCGCCGTCTGACCGGGAAGGTGGTGATCGCCACGCACAATGCCGGCAAACTCACCGAGATGCGCGAGCTGCTCGC
GCCGTTCGGAATCGAGGCGGTGTCGGCGGGCGAACTCGGCCTGCCCGAGCCCGATGAGACCGGCACCCTGTTCGCCGAGA
ACGCGGCCATCAAGGCGCAAGCTGCGGCCGAGGCCACCGGACTGCCGGCCTTCGCCGACGATTCCGGCCTGTGCGTCGAC
GCCCTCGACGGGGCGCCGGGCATCTTCTCCGCCCGCTGGGCCGGCCCGACCAAGGACTTCGCCGGCGCGATGGCGCGGAT
CTTCGCCGAACTCGACCGGCGCGGCGCGGCCGACCGCCGGGCGCACTTCGTGTCCGCCCTGGTGCTGGCCTGGCCGGACG
GACACACCGAGCTGTTCGAGGGACGGGTGTTCGGCGACCTCGTCGCCGCGAAGGGCTCCGCGGGCTTCGGCTACGACCCG
ATCTTCCGGCCGGACGGCCACGACCGCACCTTCGGCGAGATGACCGCCGAGGAGAAGCACGGCGTCGACTGGCAGAAGGG
GCGGGGCCTGTCCCACCGCGCCCGCGCCTTCGTCGAGCTGAGCCGCGCCTGCCTCGCGCCCGGCGCCTGA

Upstream 100 bases:

>100_bases
CCGAGATGGAGCCCTTCACGCAGGAACAGCTCCTCGAACTCCTCGGCCTCGCCCGCGCCGGCACGGAGCGGCTGGTCGCC
CTGCAGAAGGAGGCCATCGC

Downstream 100 bases:

>100_bases
TTTGCCAAACGGGGCGCGGGCGCTCACATCCCCGCCATCATGTCATCGACCGGCCCGGACCATCCGACCCGCGACGCGGG
CTTCGGGATCTACCTGCACT

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MSRRLTGKVVIATHNAGKLTEMRELLAPFGIEAVSAGELGLPEPDETGTLFAENAAIKAQAAAEATGLPAFADDSGLCVD
ALDGAPGIFSARWAGPTKDFAGAMARIFAELDRRGAADRRAHFVSALVLAWPDGHTELFEGRVFGDLVAAKGSAGFGYDP
IFRPDGHDRTFGEMTAEEKHGVDWQKGRGLSHRARAFVELSRACLAPGA

Sequences:

>Translated_209_residues
MSRRLTGKVVIATHNAGKLTEMRELLAPFGIEAVSAGELGLPEPDETGTLFAENAAIKAQAAAEATGLPAFADDSGLCVD
ALDGAPGIFSARWAGPTKDFAGAMARIFAELDRRGAADRRAHFVSALVLAWPDGHTELFEGRVFGDLVAAKGSAGFGYDP
IFRPDGHDRTFGEMTAEEKHGVDWQKGRGLSHRARAFVELSRACLAPGA
>Mature_208_residues
SRRLTGKVVIATHNAGKLTEMRELLAPFGIEAVSAGELGLPEPDETGTLFAENAAIKAQAAAEATGLPAFADDSGLCVDA
LDGAPGIFSARWAGPTKDFAGAMARIFAELDRRGAADRRAHFVSALVLAWPDGHTELFEGRVFGDLVAAKGSAGFGYDPI
FRPDGHDRTFGEMTAEEKHGVDWQKGRGLSHRARAFVELSRACLAPGA

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=208, Percent_Identity=32.2115384615385, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI31657144, Length=175, Percent_Identity=31.4285714285714, Blast_Score=77, Evalue=7e-15,
Organism=Escherichia coli, GI1789324, Length=193, Percent_Identity=39.3782383419689, Blast_Score=120, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17556833, Length=200, Percent_Identity=31, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322529, Length=206, Percent_Identity=27.6699029126214, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22078; Mature: 21947

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRLTGKVVIATHNAGKLTEMRELLAPFGIEAVSAGELGLPEPDETGTLFAENAAIKAQ
CCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEECCCCCCCCCCCCCCEEEECCCCHHHH
AAAEATGLPAFADDSGLCVDALDGAPGIFSARWAGPTKDFAGAMARIFAELDRRGAADRR
HHHHHCCCCCCCCCCCCEEECCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHH
AHFVSALVLAWPDGHTELFEGRVFGDLVAAKGSAGFGYDPIFRPDGHDRTFGEMTAEEKH
HHHHHHHEEECCCCCHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHC
GVDWQKGRGLSHRARAFVELSRACLAPGA
CCCHHHCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SRRLTGKVVIATHNAGKLTEMRELLAPFGIEAVSAGELGLPEPDETGTLFAENAAIKAQ
CCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEECCCCCCCCCCCCCCEEEECCCCHHHH
AAAEATGLPAFADDSGLCVDALDGAPGIFSARWAGPTKDFAGAMARIFAELDRRGAADRR
HHHHHCCCCCCCCCCCCEEECCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHH
AHFVSALVLAWPDGHTELFEGRVFGDLVAAKGSAGFGYDPIFRPDGHDRTFGEMTAEEKH
HHHHHHHEEECCCCCHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHC
GVDWQKGRGLSHRARAFVELSRACLAPGA
CCCHHHCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]