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The map label for this gene is dhaK [H]

Identifier: 170749296

GI number: 170749296

Start: 3040718

End: 3042346

Strand: Reverse

Name: dhaK [H]

Synonym: Mrad2831_2889

Alternate gene names: 170749296

Gene position: 3042346-3040718 (Counterclockwise)

Preceding gene: 170749297

Following gene: 170749295

Centisome position: 50.06

GC content: 76.8

Gene sequence:

>1629_bases
ATGGCCCATTTCATCGACGCCCGCTCCACCCTGGTCAACGATGCGGTCGACGGCCTCGTCGCGGCCAGCGGCGGACGCTT
GGCGCGGCTCGACGGCGACCCGGGCATCCGCGTCGTTCTCCGCGCCGCTCCGGATTCCGGGAAGGTCGCGGTCGTCTCCG
GCGGCGGCTCCGGTCACGAGCCGGCCCATGCCGGCTTCGTCGGGCCGGGCCTGCTGAGCGCCGCCGTCTGCGGCGACGTC
TTCGCCTCGCCGAGCGTCGACGCGGTCCTGGCCGGGATCCTCGCGGTGACGGGACCGGCCGGGTGCCTGCTCGTCATCAA
GAACTACGCGGGCGACCGGTTGAACTTCGGCCTCGCCGCCGAGCGCGCCCGGGCGCTGGGCCACAAGGTCGAGACCGTGA
TCGTGTCGGACGACATCGCCCTCCCGGACGCCAAGCAGCCCCGCGGCGTCGCCGGGACGCTGTTCGTGCACAAGGTGGCG
GGTCACGCCGCGGAGGCCGGAGAACCGCTCGAGACCGTGGCGGCGCTCGCCCGCCGGGCCGCCGGGGCGGCGAAGTCGCT
CGGCATCGCGGTCTCGACCTGCACGATCCCCGGCTCGGCGCGCAGCGAGCGGCTGGCGGAGGGGCAGGCCGAACTCGGCC
TCGGTATCCACGGCGAGCCCGGCGCGGAGCGCATCGCCCTGCCCAAGGCCAGCGAGCTCGCCCGCATGATGGCCGAGCGT
CTCGCGCGGTCCGTCCCGGGCGCGGACGGGCTGGCGCTGCTCGTGAACAATCTCGGCTCCGCCTCCGCCCTGGAGATGCA
GATCCTCACCCGGGCGGTGCTCGCGACCGATCTGGGCCGGCGCGTCCGCCTGCTGCTCGGGCCCGCCCCGCTGATGACGG
CGCTCGACATGCACGGCGCCTCGCTGTCGGTCCTGCCGCTCGACGACGCGCTGGAGCGCGCCCTGTCGGAGCCCGTCCCG
GTCCCGGCCTGGCCCGCGGCGGTCCGGGTCGAGCCGCCGATCCTGCGGCCGGTGCCCGAGGGGCTCGCGGGCGAGGCCTT
CGCGCCGTCGCACGACGCCGTCACCGCTGCCCGGATCCGGGCCGTCGCCGAGGCCCTGATCCGGGCCGAGGGTTCTCTGA
ACAGCCTCGATGCCAAGGTCGGCGACGGCGACGCCGGCACGACCTTCGCGGGCGCGGCCCGCGCCGTCCAGGCCGATCTC
GACCGGCTGCCCCAGACCGAACCCGCGGCCCTGTGCCGGGCGCTCGCCGAGCGGATCGGGCGCGCGGTCGGCGGATCGAG
CGGCGTGCTCGGATCGATCTTCTTCGCCGCGACGGCCTCGGCCCTCGCCGACGGCGCCGCGTGGCCCGAGGCTCTCGGGC
AGGGGGTGGCGCGCGTCCAGGGCTACGGCGGCGCTAAGGCCGGCGACCGCACCCTGCTCGACGCCCTGATCCCAGCCGTG
GAGGCGCTGAAGAACGGCGATCTGGCCGCCGCCGCGGCGGCCGCCCGGGCCGGTGCCGAGGCCACGGCCGGGATGGAGCG
CGCCGGCGCGGGCCGCTCGAGCTACCTGGCGGCCGGGGACCTCGCCGGTGTCCAGGATCCCGGCGCCGCCGGCGTGGCGG
CAGCGTTCGCGGCTCTGGCCGGCGCCTAG

Upstream 100 bases:

>100_bases
GCGGGGACGGAGACCGTTGCCAGCAGGGCTCGACAGCGCGGACAATGCGCGCTGATCCGCCGGCGCAGAATCGCGGGCCG
GCCCCATCGAAGGTCACGCC

Downstream 100 bases:

>100_bases
GAACAGGGCGCCGCGCGTCGTCGCACGGCGACCGTTGACGCACCTTCCACCGAGGCCTAACCCCCTCTCATGCGCACCTG
CCTGATCCTCGACGATTACC

Product: Glycerone kinase

Products: NA

Alternate protein names: DHA kinase; Glycerone kinase [H]

Number of amino acids: Translated: 542; Mature: 541

Protein sequence:

>542_residues
MAHFIDARSTLVNDAVDGLVAASGGRLARLDGDPGIRVVLRAAPDSGKVAVVSGGGSGHEPAHAGFVGPGLLSAAVCGDV
FASPSVDAVLAGILAVTGPAGCLLVIKNYAGDRLNFGLAAERARALGHKVETVIVSDDIALPDAKQPRGVAGTLFVHKVA
GHAAEAGEPLETVAALARRAAGAAKSLGIAVSTCTIPGSARSERLAEGQAELGLGIHGEPGAERIALPKASELARMMAER
LARSVPGADGLALLVNNLGSASALEMQILTRAVLATDLGRRVRLLLGPAPLMTALDMHGASLSVLPLDDALERALSEPVP
VPAWPAAVRVEPPILRPVPEGLAGEAFAPSHDAVTAARIRAVAEALIRAEGSLNSLDAKVGDGDAGTTFAGAARAVQADL
DRLPQTEPAALCRALAERIGRAVGGSSGVLGSIFFAATASALADGAAWPEALGQGVARVQGYGGAKAGDRTLLDALIPAV
EALKNGDLAAAAAAARAGAEATAGMERAGAGRSSYLAAGDLAGVQDPGAAGVAAAFAALAGA

Sequences:

>Translated_542_residues
MAHFIDARSTLVNDAVDGLVAASGGRLARLDGDPGIRVVLRAAPDSGKVAVVSGGGSGHEPAHAGFVGPGLLSAAVCGDV
FASPSVDAVLAGILAVTGPAGCLLVIKNYAGDRLNFGLAAERARALGHKVETVIVSDDIALPDAKQPRGVAGTLFVHKVA
GHAAEAGEPLETVAALARRAAGAAKSLGIAVSTCTIPGSARSERLAEGQAELGLGIHGEPGAERIALPKASELARMMAER
LARSVPGADGLALLVNNLGSASALEMQILTRAVLATDLGRRVRLLLGPAPLMTALDMHGASLSVLPLDDALERALSEPVP
VPAWPAAVRVEPPILRPVPEGLAGEAFAPSHDAVTAARIRAVAEALIRAEGSLNSLDAKVGDGDAGTTFAGAARAVQADL
DRLPQTEPAALCRALAERIGRAVGGSSGVLGSIFFAATASALADGAAWPEALGQGVARVQGYGGAKAGDRTLLDALIPAV
EALKNGDLAAAAAAARAGAEATAGMERAGAGRSSYLAAGDLAGVQDPGAAGVAAAFAALAGA
>Mature_541_residues
AHFIDARSTLVNDAVDGLVAASGGRLARLDGDPGIRVVLRAAPDSGKVAVVSGGGSGHEPAHAGFVGPGLLSAAVCGDVF
ASPSVDAVLAGILAVTGPAGCLLVIKNYAGDRLNFGLAAERARALGHKVETVIVSDDIALPDAKQPRGVAGTLFVHKVAG
HAAEAGEPLETVAALARRAAGAAKSLGIAVSTCTIPGSARSERLAEGQAELGLGIHGEPGAERIALPKASELARMMAERL
ARSVPGADGLALLVNNLGSASALEMQILTRAVLATDLGRRVRLLLGPAPLMTALDMHGASLSVLPLDDALERALSEPVPV
PAWPAAVRVEPPILRPVPEGLAGEAFAPSHDAVTAARIRAVAEALIRAEGSLNSLDAKVGDGDAGTTFAGAARAVQADLD
RLPQTEPAALCRALAERIGRAVGGSSGVLGSIFFAATASALADGAAWPEALGQGVARVQGYGGAKAGDRTLLDALIPAVE
ALKNGDLAAAAAAARAGAEATAGMERAGAGRSSYLAAGDLAGVQDPGAAGVAAAFAALAGA

Specific function: Catalyzes the phosphorylation of dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=566, Percent_Identity=40.4593639575972, Blast_Score=311, Evalue=1e-84,
Organism=Escherichia coli, GI87081857, Length=355, Percent_Identity=36.3380281690141, Blast_Score=184, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17565018, Length=553, Percent_Identity=35.9855334538879, Blast_Score=290, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6323570, Length=561, Percent_Identity=33.3333333333333, Blast_Score=246, Evalue=8e-66,
Organism=Saccharomyces cerevisiae, GI6321055, Length=550, Percent_Identity=34.7272727272727, Blast_Score=229, Evalue=1e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR004007
- InterPro:   IPR012734 [H]

Pfam domain/function: PF02733 Dak1; PF02734 Dak2 [H]

EC number: =2.7.1.29 [H]

Molecular weight: Translated: 53692; Mature: 53561

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHFIDARSTLVNDAVDGLVAASGGRLARLDGDPGIRVVLRAAPDSGKVAVVSGGGSGHE
CCCCHHHHHHHHHHHHHHHEECCCCCEEEECCCCCEEEEEEECCCCCCEEEEECCCCCCC
PAHAGFVGPGLLSAAVCGDVFASPSVDAVLAGILAVTGPAGCLLVIKNYAGDRLNFGLAA
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHH
ERARALGHKVETVIVSDDIALPDAKQPRGVAGTLFVHKVAGHAAEAGEPLETVAALARRA
HHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCHHCCCCHHHHHHHHHHHH
AGAAKSLGIAVSTCTIPGSARSERLAEGQAELGLGIHGEPGAERIALPKASELARMMAER
CCCHHHCCEEEEEEECCCCHHHHHHHCCHHHHCCCCCCCCCCCEECCCCHHHHHHHHHHH
LARSVPGADGLALLVNNLGSASALEMQILTRAVLATDLGRRVRLLLGPAPLMTALDMHGA
HHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHCCCC
SLSVLPLDDALERALSEPVPVPAWPAAVRVEPPILRPVPEGLAGEAFAPSHDAVTAARIR
EEEEEECHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
AVAEALIRAEGSLNSLDAKVGDGDAGTTFAGAARAVQADLDRLPQTEPAALCRALAERIG
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RAVGGSSGVLGSIFFAATASALADGAAWPEALGQGVARVQGYGGAKAGDRTLLDALIPAV
HHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
EALKNGDLAAAAAAARAGAEATAGMERAGAGRSSYLAAGDLAGVQDPGAAGVAAAFAALA
HHHCCCCHHHHHHHHHCCCHHHHCHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHH
GA
CC
>Mature Secondary Structure 
AHFIDARSTLVNDAVDGLVAASGGRLARLDGDPGIRVVLRAAPDSGKVAVVSGGGSGHE
CCCHHHHHHHHHHHHHHHEECCCCCEEEECCCCCEEEEEEECCCCCCEEEEECCCCCCC
PAHAGFVGPGLLSAAVCGDVFASPSVDAVLAGILAVTGPAGCLLVIKNYAGDRLNFGLAA
CCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHH
ERARALGHKVETVIVSDDIALPDAKQPRGVAGTLFVHKVAGHAAEAGEPLETVAALARRA
HHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCHHCCCCHHHHHHHHHHHH
AGAAKSLGIAVSTCTIPGSARSERLAEGQAELGLGIHGEPGAERIALPKASELARMMAER
CCCHHHCCEEEEEEECCCCHHHHHHHCCHHHHCCCCCCCCCCCEECCCCHHHHHHHHHHH
LARSVPGADGLALLVNNLGSASALEMQILTRAVLATDLGRRVRLLLGPAPLMTALDMHGA
HHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHCCCC
SLSVLPLDDALERALSEPVPVPAWPAAVRVEPPILRPVPEGLAGEAFAPSHDAVTAARIR
EEEEEECHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
AVAEALIRAEGSLNSLDAKVGDGDAGTTFAGAARAVQADLDRLPQTEPAALCRALAERIG
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RAVGGSSGVLGSIFFAATASALADGAAWPEALGQGVARVQGYGGAKAGDRTLLDALIPAV
HHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
EALKNGDLAAAAAAARAGAEATAGMERAGAGRSSYLAAGDLAGVQDPGAAGVAAAFAALA
HHHCCCCHHHHHHHHHCCCHHHHCHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHH
GA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA