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The map label for this gene is prpB [C]

Identifier: 170749181

GI number: 170749181

Start: 2912461

End: 2913291

Strand: Reverse

Name: prpB [C]

Synonym: Mrad2831_2774

Alternate gene names: 170749181

Gene position: 2913291-2912461 (Counterclockwise)

Preceding gene: 170749182

Following gene: 170749180

Centisome position: 47.93

GC content: 73.16

Gene sequence:

>831_bases
ATGGCCGACCTAGAGGCGAAACATCGGGTCTTCGTGGCGCTGCACGAGCGGCCGGGCGCGTTCGTCGTGGCCAACCCATG
GGACGCGGGTTCGTCGCGGATCCTGAACGCCCTCGGTTACGAGGCGCTGGCGACGACGAGCGCCGGGTTCGCGTTCGCCG
TCGGACGGCGGGACTCCACCGCCTCGCTGTCGCGCGACGCGATCTTGGAGAACGCCCGCGCCATCGTGGACGCGACCCAC
CTGCCCGTGACGGCCGATCTGGAGGACGGGTTCGGGACCGACCCGGAGGCGTGCGCGCTGACGATCGCCCGGGCCTCAGA
GATCGGGCTGGTCGGCGGCTCGATAGAGGACGCCACGGGCGACGCCGCCAGTCCGATCTTCGATTTCGGTCACGCCGTCG
AGCGAGTCGCCGCCGCGGCCGAGGCCGCGCGCCGGCTCCCGTTCGTGCTGACCGCGCGCGCCGAGAACCACCTGTGCGGG
CGGCCCGACCTCGACGACACGATCCGCCGCCTCCAGGCCTTCGAGGGGGCGGGAGCGCACGTCCTCTACGCGCCGAACCT
GCCGGACCTCGAGGCCATTCGGGCGGTCTGTGCCGCGGTCAGCCGCCCGGTGAACGTCGTCGCCGGCCTGTCGCCCCGGC
AATACACGGTGGCCGAGCTGGAGGCGGCGGGCGTCAAGCGGATCAGCGTCGGCGGGTCTTTCGCGCGGGCGGCCCTCGGC
GGTCTCGCGCGCGCGGCGCGGGAGGTGCTGGACCGGGGCACCTTCACCTACGCGGCGGAGGCGATGTCGGGAAGCGAGGC
GAGATCGTACATGGCGGAGGCGACTCGGTAG

Upstream 100 bases:

>100_bases
GGACCATCCGACTTCGGCCCCGACGTCGGTCGATCCGGTGCCACACCCGCCGTTTCCCCGGGCCGCCCGAGCAGCGTAGG
ATCGATCCACGGGGGTGCGC

Downstream 100 bases:

>100_bases
GCGCGACCGCTCGGCATCGCGGTCCGTCATCCCGCAAACCGGCGGCGACCGAGCGCCGCCGGGCCGATCGGCCCGAACGC
TCGAGCCGAAGCCGACGACC

Product: hypothetical protein

Products: Pyruvate; Succinate [C]

Alternate protein names: Carboxyvinyl-Carboxyphosphonate Phosphorylmutase; PEP Phosphonomutase And Related S-Like Protein; Transferase; Phosphorylmutase; PEP Phosphonomutase-Like Protein; Methylisocitrate Lyase; Carboxyphosphonoenolpyruvate Phosphonomutase-Like Protein; Carboxyphosphonoenolpyruvate Phosphonomutase Protein; PEP Phosphonomutase-Like; Carboxyvinyl-Carboxyphosphonatephosphorylmutase; PEP Phosphonomutase Protein; PEP Phosphonomutase And Related -Like Protein; 2-Methylisocitrate Lyase

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MADLEAKHRVFVALHERPGAFVVANPWDAGSSRILNALGYEALATTSAGFAFAVGRRDSTASLSRDAILENARAIVDATH
LPVTADLEDGFGTDPEACALTIARASEIGLVGGSIEDATGDAASPIFDFGHAVERVAAAAEAARRLPFVLTARAENHLCG
RPDLDDTIRRLQAFEGAGAHVLYAPNLPDLEAIRAVCAAVSRPVNVVAGLSPRQYTVAELEAAGVKRISVGGSFARAALG
GLARAAREVLDRGTFTYAAEAMSGSEARSYMAEATR

Sequences:

>Translated_276_residues
MADLEAKHRVFVALHERPGAFVVANPWDAGSSRILNALGYEALATTSAGFAFAVGRRDSTASLSRDAILENARAIVDATH
LPVTADLEDGFGTDPEACALTIARASEIGLVGGSIEDATGDAASPIFDFGHAVERVAAAAEAARRLPFVLTARAENHLCG
RPDLDDTIRRLQAFEGAGAHVLYAPNLPDLEAIRAVCAAVSRPVNVVAGLSPRQYTVAELEAAGVKRISVGGSFARAALG
GLARAAREVLDRGTFTYAAEAMSGSEARSYMAEATR
>Mature_275_residues
ADLEAKHRVFVALHERPGAFVVANPWDAGSSRILNALGYEALATTSAGFAFAVGRRDSTASLSRDAILENARAIVDATHL
PVTADLEDGFGTDPEACALTIARASEIGLVGGSIEDATGDAASPIFDFGHAVERVAAAAEAARRLPFVLTARAENHLCGR
PDLDDTIRRLQAFEGAGAHVLYAPNLPDLEAIRAVCAAVSRPVNVVAGLSPRQYTVAELEAAGVKRISVGGSFARAALGG
LARAAREVLDRGTFTYAAEAMSGSEARSYMAEATR

Specific function: Catalyzes The Formation Of Pyruvate And Succinate From 2-Methylisocitrate (By Similarity). [C]

COG id: COG2513

COG function: function code G; PEP phosphonomutase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.1.3.30 [C]

Molecular weight: Translated: 28803; Mature: 28671

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLEAKHRVFVALHERPGAFVVANPWDAGSSRILNALGYEALATTSAGFAFAVGRRDST
CCCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHCHHHHHHCCCCEEEEECCCCCC
ASLSRDAILENARAIVDATHLPVTADLEDGFGTDPEACALTIARASEIGLVGGSIEDATG
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHEEEEEHHCCCEEECCCCCCCCC
DAASPIFDFGHAVERVAAAAEAARRLPFVLTARAENHLCGRPDLDDTIRRLQAFEGAGAH
CCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCE
VLYAPNLPDLEAIRAVCAAVSRPVNVVAGLSPRQYTVAELEAAGVKRISVGGSFARAALG
EEECCCCCCHHHHHHHHHHHCCCHHEEECCCCCCCHHHHHHHCCCEEEECCCHHHHHHHH
GLARAAREVLDRGTFTYAAEAMSGSEARSYMAEATR
HHHHHHHHHHHCCCCEEHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure 
ADLEAKHRVFVALHERPGAFVVANPWDAGSSRILNALGYEALATTSAGFAFAVGRRDST
CCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHCHHHHHHCCCCEEEEECCCCCC
ASLSRDAILENARAIVDATHLPVTADLEDGFGTDPEACALTIARASEIGLVGGSIEDATG
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHEEEEEHHCCCEEECCCCCCCCC
DAASPIFDFGHAVERVAAAAEAARRLPFVLTARAENHLCGRPDLDDTIRRLQAFEGAGAH
CCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCE
VLYAPNLPDLEAIRAVCAAVSRPVNVVAGLSPRQYTVAELEAAGVKRISVGGSFARAALG
EEECCCCCCHHHHHHHHHHHCCCHHEEECCCCCCCHHHHHHHCCCEEEECCCHHHHHHHH
GLARAAREVLDRGTFTYAAEAMSGSEARSYMAEATR
HHHHHHHHHHHCCCCEEHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: methylisocitrate [C]

Specific reaction: methylisocitrate <==> Pyruvate + Succinate [C]

General reaction: Elimination [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA