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The map label for this gene is murB [H]

Identifier: 170748772

GI number: 170748772

Start: 2490160

End: 2491086

Strand: Reverse

Name: murB [H]

Synonym: Mrad2831_2354

Alternate gene names: 170748772

Gene position: 2491086-2490160 (Counterclockwise)

Preceding gene: 170748773

Following gene: 170748771

Centisome position: 40.99

GC content: 74.76

Gene sequence:

>927_bases
ATGACCGCCTCTCTGCACGATCGCATCCGGGCCGCTGCGCCCGACCTCCGCGGGCGCCTGCTCGCCGACCAGCCGCTCGC
CGACCTCACCTGGTTCCGGGTCGGCGGACCGGCCGAGGTCCTGTTCACCCCGGCCGACGAGGAGGATCTCGCCCGCCTCC
TCGCCTCCCTCGATCCGGACGTGCCGGTCACGGTGATCGGGCTCGGCTCGAACCTGATCGTGCGGGACGGCGGCGTGCCG
GGCGTCGTGGTCCGCCTCGGCGGCAAGGCCTTCGGCAGCATCGCGATCGACGGCGACGCGCTGACCGTCGGCACCGCGGT
CCCGGACATGCGCCTCGCCAAGGCGGCCGCCGAGGCCGGGCTCGACGGGCTCGCCTTCTATCGCGGCATTCCCGGGTCGA
TCGGCGGCGCGCTCCGCATGAACGCGGGCGCGCATGGCGGCGAGACCACCGACGTGCTGGTGGAAGCCCGCGGGATCGAC
CGCGGGGGCGCGCTGCGCACCTTCAGCCACGCCGACATGGGCTTCTCCTACCGGCATTCGGACGCCCCGGAGGACGTGAT
CTTCACGCGCGCCGTCTTCCGCGGCCGGACCGGCGACCGCGGGGCGATCGAGGCCGAGATGGAACGGGTCACGGCCGCCC
GGGAGGCCGCGCAGCCGATCCGCGAGCGGACCGGCGGCTCGACCTTCGCCAACCCGGACGGCGGCAAGGCGTGGCAGCTG
ATCGACGCCGCCGGCTGCCGCGGGCTCAGGCGGGGCGGCGCCCAGGTCAGCGAGATGCACTGCAACTTCCTGATCAATAC
CGGTGACGCGACCGCGGCCGACATCGAGGGGCTGGGCGAGGAGGTTCGCCGCCGCGTCCGCGACACCAGCGGGGTCGAGC
TGCGCTGGGAGATCCGGCGCATCGGCCGGCCCACCGGCGCCGCGTGA

Upstream 100 bases:

>100_bases
TCCGGACCCCGGCCTCGCAGCGTCCGCTGCCACCCCGATGCGACGACACCAGGATCGCCGCATCCCTCTCCCCGCGGGCG
GGGCGAGGGGAGACACACAG

Downstream 100 bases:

>100_bases
GAGCGGTCTTCCGGACGCGCCGACGCGGCCGAGATACGATGCTCGGCCGGCGCAGCGACCGTTCGGGTGCGTTCAGATCC
TGATTGAAGCCGACCTTTTC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTASLHDRIRAAAPDLRGRLLADQPLADLTWFRVGGPAEVLFTPADEEDLARLLASLDPDVPVTVIGLGSNLIVRDGGVP
GVVVRLGGKAFGSIAIDGDALTVGTAVPDMRLAKAAAEAGLDGLAFYRGIPGSIGGALRMNAGAHGGETTDVLVEARGID
RGGALRTFSHADMGFSYRHSDAPEDVIFTRAVFRGRTGDRGAIEAEMERVTAAREAAQPIRERTGGSTFANPDGGKAWQL
IDAAGCRGLRRGGAQVSEMHCNFLINTGDATAADIEGLGEEVRRRVRDTSGVELRWEIRRIGRPTGAA

Sequences:

>Translated_308_residues
MTASLHDRIRAAAPDLRGRLLADQPLADLTWFRVGGPAEVLFTPADEEDLARLLASLDPDVPVTVIGLGSNLIVRDGGVP
GVVVRLGGKAFGSIAIDGDALTVGTAVPDMRLAKAAAEAGLDGLAFYRGIPGSIGGALRMNAGAHGGETTDVLVEARGID
RGGALRTFSHADMGFSYRHSDAPEDVIFTRAVFRGRTGDRGAIEAEMERVTAAREAAQPIRERTGGSTFANPDGGKAWQL
IDAAGCRGLRRGGAQVSEMHCNFLINTGDATAADIEGLGEEVRRRVRDTSGVELRWEIRRIGRPTGAA
>Mature_307_residues
TASLHDRIRAAAPDLRGRLLADQPLADLTWFRVGGPAEVLFTPADEEDLARLLASLDPDVPVTVIGLGSNLIVRDGGVPG
VVVRLGGKAFGSIAIDGDALTVGTAVPDMRLAKAAAEAGLDGLAFYRGIPGSIGGALRMNAGAHGGETTDVLVEARGIDR
GGALRTFSHADMGFSYRHSDAPEDVIFTRAVFRGRTGDRGAIEAEMERVTAAREAAQPIRERTGGSTFANPDGGKAWQLI
DAAGCRGLRRGGAQVSEMHCNFLINTGDATAADIEGLGEEVRRRVRDTSGVELRWEIRRIGRPTGAA

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 32374; Mature: 32243

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASLHDRIRAAAPDLRGRLLADQPLADLTWFRVGGPAEVLFTPADEEDLARLLASLDPD
CCCCHHHHHHHCCCCHHCCEECCCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHCCCC
VPVTVIGLGSNLIVRDGGVPGVVVRLGGKAFGSIAIDGDALTVGTAVPDMRLAKAAAEAG
CCEEEEECCCCEEEECCCCCEEEEEECCCEEEEEEECCCEEEECCCCCCHHHHHHHHHCC
LDGLAFYRGIPGSIGGALRMNAGAHGGETTDVLVEARGIDRGGALRTFSHADMGFSYRHS
CCHHHHHCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCEEEECCCCCCCEECCC
DAPEDVIFTRAVFRGRTGDRGAIEAEMERVTAAREAAQPIRERTGGSTFANPDGGKAWQL
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
IDAAGCRGLRRGGAQVSEMHCNFLINTGDATAADIEGLGEEVRRRVRDTSGVELRWEIRR
EEHHCCHHHHHCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
IGRPTGAA
CCCCCCCC
>Mature Secondary Structure 
TASLHDRIRAAAPDLRGRLLADQPLADLTWFRVGGPAEVLFTPADEEDLARLLASLDPD
CCCHHHHHHHCCCCHHCCEECCCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHCCCC
VPVTVIGLGSNLIVRDGGVPGVVVRLGGKAFGSIAIDGDALTVGTAVPDMRLAKAAAEAG
CCEEEEECCCCEEEECCCCCEEEEEECCCEEEEEEECCCEEEECCCCCCHHHHHHHHHCC
LDGLAFYRGIPGSIGGALRMNAGAHGGETTDVLVEARGIDRGGALRTFSHADMGFSYRHS
CCHHHHHCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCEEEECCCCCCCEECCC
DAPEDVIFTRAVFRGRTGDRGAIEAEMERVTAAREAAQPIRERTGGSTFANPDGGKAWQL
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
IDAAGCRGLRRGGAQVSEMHCNFLINTGDATAADIEGLGEEVRRRVRDTSGVELRWEIRR
EEHHCCHHHHHCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
IGRPTGAA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA