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The map label for this gene is qor [H]

Identifier: 170748062

GI number: 170748062

Start: 1753023

End: 1754000

Strand: Reverse

Name: qor [H]

Synonym: Mrad2831_1644

Alternate gene names: 170748062

Gene position: 1754000-1753023 (Counterclockwise)

Preceding gene: 170748070

Following gene: 170748061

Centisome position: 28.86

GC content: 72.19

Gene sequence:

>978_bases
ATGCCGAAGGCGATCCGGGTCTACGAATATGGCGGCCCCGAGGTGATGCGCTTCGAGGACGTGCCCCTGGCCGAGCCGGG
CCCCGGGCAGATCCGGGTCAAGCAGGCCGCCATCGGCGTCAACTTCATCGACATCTACTTCCGCACCGGCGCCTACAAGT
CCCCGCACATGCCCTACACCCCCGGCAAGGAGGGCGCCGGCACCGTCACGGCGGTGGGCGAGGGCGTCAGCCAGTTCAAG
CCCGGCGACCGAGTCGCCTACGGTTCGGTGGCGGACGGCTGCTACGCCGAGGAGCCGGTGATCCCGGCCTCCGCGGCCGT
GCCGATCCCGGACGGCGTCGACGAGAAGACCGCCGCCGCCATGATGCTCAAGGGCCTGACCGTCGAGTACCTGCTGCACC
GGACCTACGCGGTGAAGCCCGGCGACACGATCCTGTGGCAGGCGGCCGCCGGCGGCGTCGGCCTGATCGCCTGCCAGTGG
GCCAAGCACCTCGGCGCCACCGTGATCGGCACCGCCGGCAGCCCCGAGAAGGCGGAGCTCGCCAAGCGGAACGGCTGCGA
CCACGTCATCCTCTACCGCGAGGAGGACGTGGCCAAGCGCGTGCGCGAGATCACCGGCGGCAAGGGCGTGCCGGTGGTCT
ACGACGGCGTCGGCCAGGCGACCCTGATGGGCTCGCTGGACAGCCTCGCGCCGCTCGGCCTGCTGGCGAGCTTCGGCTCG
GCCTCCGGGGCGATCACCGGGCTCGACCTCGGCCTGCTCGCCCCGCGCGGCTCGCTCTACGTGACGCGCCCGACACTCGC
GACCTTCTCGTCGAACCGCGCCACCCTGGAGGAGGCGGCCGGCCGCCTGTTCAAGGTGGTCGGCGACGGCGCGGTGAAGA
TCGCCGTCAACGCCACCTACCCGCTGGCCGAGGCGCAGCAGGTCCACCGCGACCTCGCGGGCCGGGAGACCACCGGCTCG
ATCGTGATGCTGCCCTGA

Upstream 100 bases:

>100_bases
AACCGGAGCGCGAGACGGCAAAAACAAATTGCCTCCGCCGGGCGGTCCGTTATCTCGGGCTGCAACGCCCCCGCGTGGGG
CGGCGAGCGGGAGTCCAACG

Downstream 100 bases:

>100_bases
GGCAGGCGACCATGACGCCCGGCAGCGCCGACCTGCTCCTCGTCGTCGACGTGCAGGTCGATTTCCTGCCGGGCGGGGCG
CTCCCGGTCCCGGAAGGCGA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MPKAIRVYEYGGPEVMRFEDVPLAEPGPGQIRVKQAAIGVNFIDIYFRTGAYKSPHMPYTPGKEGAGTVTAVGEGVSQFK
PGDRVAYGSVADGCYAEEPVIPASAAVPIPDGVDEKTAAAMMLKGLTVEYLLHRTYAVKPGDTILWQAAAGGVGLIACQW
AKHLGATVIGTAGSPEKAELAKRNGCDHVILYREEDVAKRVREITGGKGVPVVYDGVGQATLMGSLDSLAPLGLLASFGS
ASGAITGLDLGLLAPRGSLYVTRPTLATFSSNRATLEEAAGRLFKVVGDGAVKIAVNATYPLAEAQQVHRDLAGRETTGS
IVMLP

Sequences:

>Translated_325_residues
MPKAIRVYEYGGPEVMRFEDVPLAEPGPGQIRVKQAAIGVNFIDIYFRTGAYKSPHMPYTPGKEGAGTVTAVGEGVSQFK
PGDRVAYGSVADGCYAEEPVIPASAAVPIPDGVDEKTAAAMMLKGLTVEYLLHRTYAVKPGDTILWQAAAGGVGLIACQW
AKHLGATVIGTAGSPEKAELAKRNGCDHVILYREEDVAKRVREITGGKGVPVVYDGVGQATLMGSLDSLAPLGLLASFGS
ASGAITGLDLGLLAPRGSLYVTRPTLATFSSNRATLEEAAGRLFKVVGDGAVKIAVNATYPLAEAQQVHRDLAGRETTGS
IVMLP
>Mature_324_residues
PKAIRVYEYGGPEVMRFEDVPLAEPGPGQIRVKQAAIGVNFIDIYFRTGAYKSPHMPYTPGKEGAGTVTAVGEGVSQFKP
GDRVAYGSVADGCYAEEPVIPASAAVPIPDGVDEKTAAAMMLKGLTVEYLLHRTYAVKPGDTILWQAAAGGVGLIACQWA
KHLGATVIGTAGSPEKAELAKRNGCDHVILYREEDVAKRVREITGGKGVPVVYDGVGQATLMGSLDSLAPLGLLASFGSA
SGAITGLDLGLLAPRGSLYVTRPTLATFSSNRATLEEAAGRLFKVVGDGAVKIAVNATYPLAEAQQVHRDLAGRETTGSI
VMLP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=31.6109422492401, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=31.6109422492401, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI194239676, Length=327, Percent_Identity=29.9694189602446, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI18379349, Length=314, Percent_Identity=30.8917197452229, Blast_Score=134, Evalue=8e-32,
Organism=Homo sapiens, GI28557745, Length=230, Percent_Identity=36.9565217391304, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI22538446, Length=328, Percent_Identity=29.8780487804878, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI22538444, Length=328, Percent_Identity=29.8780487804878, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI24308257, Length=342, Percent_Identity=26.3157894736842, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI197927207, Length=191, Percent_Identity=27.7486910994764, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI67078404, Length=202, Percent_Identity=29.7029702970297, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI47519420, Length=342, Percent_Identity=25.4385964912281, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI67078406, Length=160, Percent_Identity=30.625, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=48.3180428134557, Blast_Score=305, Evalue=2e-84,
Organism=Escherichia coli, GI87081918, Length=207, Percent_Identity=29.951690821256, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790045, Length=223, Percent_Identity=27.8026905829596, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=324, Percent_Identity=29.320987654321, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17556000, Length=256, Percent_Identity=28.90625, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=325, Percent_Identity=35.0769230769231, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6323961, Length=342, Percent_Identity=25.1461988304094, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324486, Length=342, Percent_Identity=23.9766081871345, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33925; Mature: 33794

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKAIRVYEYGGPEVMRFEDVPLAEPGPGQIRVKQAAIGVNFIDIYFRTGAYKSPHMPYT
CCCEEEEEECCCCCEEEECCCCCCCCCCCCEEEEEEEECCEEEEEEEECCCCCCCCCCCC
PGKEGAGTVTAVGEGVSQFKPGDRVAYGSVADGCYAEEPVIPASAAVPIPDGVDEKTAAA
CCCCCCCEEEEECCCHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
MMLKGLTVEYLLHRTYAVKPGDTILWQAAAGGVGLIACQWAKHLGATVIGTAGSPEKAEL
HHHHCCHHHHHHHHHEEECCCCEEEEEECCCCCEEEEEHHHHHCCCEEEECCCCCHHHHH
AKRNGCDHVILYREEDVAKRVREITGGKGVPVVYDGVGQATLMGSLDSLAPLGLLASFGS
HHHCCCCEEEEECCHHHHHHHHHHHCCCCCCEEECCCCCEEECCCHHHHHHHHHHHHCCC
ASGAITGLDLGLLAPRGSLYVTRPTLATFSSNRATLEEAAGRLFKVVGDGAVKIAVNATY
CCCCEEEEEEEEECCCCCEEEECCCCEECCCCCHHHHHHHHHEEEEECCCEEEEEEECCC
PLAEAQQVHRDLAGRETTGSIVMLP
CHHHHHHHHHHHCCCCCCCCEEEEC
>Mature Secondary Structure 
PKAIRVYEYGGPEVMRFEDVPLAEPGPGQIRVKQAAIGVNFIDIYFRTGAYKSPHMPYT
CCEEEEEECCCCCEEEECCCCCCCCCCCCEEEEEEEECCEEEEEEEECCCCCCCCCCCC
PGKEGAGTVTAVGEGVSQFKPGDRVAYGSVADGCYAEEPVIPASAAVPIPDGVDEKTAAA
CCCCCCCEEEEECCCHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
MMLKGLTVEYLLHRTYAVKPGDTILWQAAAGGVGLIACQWAKHLGATVIGTAGSPEKAEL
HHHHCCHHHHHHHHHEEECCCCEEEEEECCCCCEEEEEHHHHHCCCEEEECCCCCHHHHH
AKRNGCDHVILYREEDVAKRVREITGGKGVPVVYDGVGQATLMGSLDSLAPLGLLASFGS
HHHCCCCEEEEECCHHHHHHHHHHHCCCCCCEEECCCCCEEECCCHHHHHHHHHHHHCCC
ASGAITGLDLGLLAPRGSLYVTRPTLATFSSNRATLEEAAGRLFKVVGDGAVKIAVNATY
CCCCEEEEEEEEECCCCCEEEECCCCEECCCCCHHHHHHHHHEEEEECCCEEEEEEECCC
PLAEAQQVHRDLAGRETTGSIVMLP
CHHHHHHHHHHHCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]