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The map label for this gene is yfcS [H]

Identifier: 170680090

GI number: 170680090

Start: 2540390

End: 2541142

Strand: Reverse

Name: yfcS [H]

Synonym: EcSMS35_2495

Alternate gene names: 170680090

Gene position: 2541142-2540390 (Counterclockwise)

Preceding gene: 170679648

Following gene: 170683183

Centisome position: 50.14

GC content: 56.97

Gene sequence:

>753_bases
ATGTCTTATAAATTATCCAGTTCAATGGTCGTCAGCACGGCGCTGGCGGCACTGCTTTCCACCGTCAGCCTGGCGGCGCA
CGCCTCGGTCACCCCGGACCGCACCCGTCTGGTGTTTAACGAAAGCGATAAATCGATCAGCGTGACGTTGCGTAACAACA
ACGAAAAGCTGCCTTACCTGGCGCAAAGCTGGCTGGAAGACGAGAAGGGCAACAAAATCACCTCGCCGCTGGCGGTACTG
CCGCCGGTGCAGCGTATTGACGCCATGATGAACGGCCAGGTGAAGATTCAGGCGCTGCCGGACATTCACACGCTGCCATC
TGACCGTGAAAGCCTGTTCTACTACAACGTGCGTGAGATCCCGCCAAAGACCGGGAAAGCCAACACCCTGCAAATTGCCC
TGCAAACGCGCATCAAGCTGTTCTGGCGACCAAAGGCGCTGGAGAAGATTGACATGAGAAAACCGTGGCAGTTTAAGGTG
ACGCTCACGCGCAGCGGCCAGGACTATACCGTCAATAACCCGACGCCATACCACGTCATCATCAGCGATGCCAGCACACA
GAAGAAAGGGCCGACCGCAGCCGGGTTTAAACCGCTGGTGATGTCGCCGAAAACGTCACAGCCGTTAAAGGCAAAAATGG
ACAGCGCCCCGGTGCTGACCTACATCAACGACTACGGCGCGCGCCTGCCGCTGATCTTCCGCTGTGAAGGGGACACCTGC
AAGGTGGATGAAGATCAAAGCAGCAAAGGCTGA

Upstream 100 bases:

>100_bases
GAAATTAAGCCTGTTATTCAGGACCAGACGCGGCAAGTCACACCAACGGAAGCGCCGACGTCAATTTCAGCTACTCAATA
ATCTGATTAAGGAACGATCA

Downstream 100 bases:

>100_bases
TAACGGGAGAGCCAGGATGAAAGGATCGTGGGCGTGGTTGCTGGTGGGCTGCATCGGTAGTTGCTCCGTGACGGCAGGGA
GCAAATCGGTGGATATGATT

Product: fimbrial chaperone protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSYKLSSSMVVSTALAALLSTVSLAAHASVTPDRTRLVFNESDKSISVTLRNNNEKLPYLAQSWLEDEKGNKITSPLAVL
PPVQRIDAMMNGQVKIQALPDIHTLPSDRESLFYYNVREIPPKTGKANTLQIALQTRIKLFWRPKALEKIDMRKPWQFKV
TLTRSGQDYTVNNPTPYHVIISDASTQKKGPTAAGFKPLVMSPKTSQPLKAKMDSAPVLTYINDYGARLPLIFRCEGDTC
KVDEDQSSKG

Sequences:

>Translated_250_residues
MSYKLSSSMVVSTALAALLSTVSLAAHASVTPDRTRLVFNESDKSISVTLRNNNEKLPYLAQSWLEDEKGNKITSPLAVL
PPVQRIDAMMNGQVKIQALPDIHTLPSDRESLFYYNVREIPPKTGKANTLQIALQTRIKLFWRPKALEKIDMRKPWQFKV
TLTRSGQDYTVNNPTPYHVIISDASTQKKGPTAAGFKPLVMSPKTSQPLKAKMDSAPVLTYINDYGARLPLIFRCEGDTC
KVDEDQSSKG
>Mature_249_residues
SYKLSSSMVVSTALAALLSTVSLAAHASVTPDRTRLVFNESDKSISVTLRNNNEKLPYLAQSWLEDEKGNKITSPLAVLP
PVQRIDAMMNGQVKIQALPDIHTLPSDRESLFYYNVREIPPKTGKANTLQIALQTRIKLFWRPKALEKIDMRKPWQFKVT
LTRSGQDYTVNNPTPYHVIISDASTQKKGPTAAGFKPLVMSPKTSQPLKAKMDSAPVLTYINDYGARLPLIFRCEGDTCK
VDEDQSSKG

Specific function: Could be required for the biogenesis of a putative fimbria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1788677, Length=221, Percent_Identity=77.8280542986425, Blast_Score=378, Evalue=1e-106,
Organism=Escherichia coli, GI1786936, Length=239, Percent_Identity=39.7489539748954, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI87082203, Length=217, Percent_Identity=40.5529953917051, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788428, Length=222, Percent_Identity=33.3333333333333, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787171, Length=230, Percent_Identity=34.3478260869565, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786333, Length=245, Percent_Identity=33.0612244897959, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1789532, Length=224, Percent_Identity=31.6964285714286, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790771, Length=225, Percent_Identity=32, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786743, Length=228, Percent_Identity=30.7017543859649, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87081806, Length=228, Percent_Identity=27.6315789473684, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 27824; Mature: 27693

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYKLSSSMVVSTALAALLSTVSLAAHASVTPDRTRLVFNESDKSISVTLRNNNEKLPYL
CCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCHH
AQSWLEDEKGNKITSPLAVLPPVQRIDAMMNGQVKIQALPDIHTLPSDRESLFYYNVREI
HHHHHCCCCCCEECCCEEECCCHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEEHEEC
PPKTGKANTLQIALQTRIKLFWRPKALEKIDMRKPWQFKVTLTRSGQDYTVNNPTPYHVI
CCCCCCCCEEEEEEEEEEEEEECCHHHHHHCCCCCEEEEEEEEECCCCEECCCCCCEEEE
ISDASTQKKGPTAAGFKPLVMSPKTSQPLKAKMDSAPVLTYINDYGARLPLIFRCEGDTC
EECCCCCCCCCCCCCCCCEEECCCCCCCHHHHCCCCCEEEEECCCCCCCCEEEEECCCEE
KVDEDQSSKG
ECCCCCCCCC
>Mature Secondary Structure 
SYKLSSSMVVSTALAALLSTVSLAAHASVTPDRTRLVFNESDKSISVTLRNNNEKLPYL
CEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCHH
AQSWLEDEKGNKITSPLAVLPPVQRIDAMMNGQVKIQALPDIHTLPSDRESLFYYNVREI
HHHHHCCCCCCEECCCEEECCCHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEEHEEC
PPKTGKANTLQIALQTRIKLFWRPKALEKIDMRKPWQFKVTLTRSGQDYTVNNPTPYHVI
CCCCCCCCEEEEEEEEEEEEEECCHHHHHHCCCCCEEEEEEEEECCCCEECCCCCCEEEE
ISDASTQKKGPTAAGFKPLVMSPKTSQPLKAKMDSAPVLTYINDYGARLPLIFRCEGDTC
EECCCCCCCCCCCCCCCCEEECCCCCCCHHHHCCCCCEEEEECCCCCCCCEEEEECCCEE
KVDEDQSSKG
ECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]