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The map label for this gene is hofD [H]

Identifier: 170079198

GI number: 170079198

Start: 2731521

End: 2732348

Strand: Reverse

Name: hofD [H]

Synonym: SYNPCC7002_A2604

Alternate gene names: 170079198

Gene position: 2732348-2731521 (Counterclockwise)

Preceding gene: 170079199

Following gene: 170079197

Centisome position: 90.83

GC content: 55.92

Gene sequence:

>828_bases
ATGCTCGCGCTTTTACAACAGTCCGGTTTACTGGCGATCGCCTTTATTTTTCTATTCATCTGGGGAGCCTGTTTCGGCAG
TTTCCTCAACGTGGTGGTTTATCGGCTGCCAGCGGGTTTATCCCTGGCACATCCCCCCTCCCGCTGTCCCCACTGTGGCC
ACCAACTAGGGGCGCAGGAAAATATTCCGGTGTTGGGTTGGCTCCTGTTGGGGGGCAAATGTCACTGGTGTAAAACGCCC
ATTGCCGCCCGGTATCCCCTCGTCGAAACGCTGATGGGCTTGCTCTGTGTTGCCACAGTGGTTCAATTTGGACTAACCCT
AGAGGCGATCGCCGCCTTTACCCTATTGTTTTGGTTAGTGGCCCTGGCCCTCATTGATTACGACACTTTTACCCTGCCCA
ACCCCTTAACCCAATCGGGCCTCGTACTCGGTCTCCTCTTCCAGATGGGGCTGGGTTTCCAGGCGAATGGCTTCCCTGGC
GCGATCTATGGGCTAATGGGTGGCATTGGGGCGGCGGTATTGGGGCTTTGGCTACTCGATGGCATTGGTGTCATTGGTTC
GGCGGTGCTGGGTCAAGAGGCCATGGGGGGCGGCGATCCGAAACTTTTGGCGATGATTGGCGCTTGGCTGGGTTGGCAAA
ACGTCCTCTTAACGGTAATTTTGGCCTGCGCCCTGGGCACGATGATTATTGGTGGGGCCATGGGCCTCGGCAAACACCAG
CGGGGTCAACATTTACCCTTTGGGCCGTTTCTTGCCTTAGGGGCAATCATTAGTCTGTTTTGGGGCGATCGCCTGATCGA
ACTCTACCTAAACGCGTTTTTGGGTTGA

Upstream 100 bases:

>100_bases
GTCAATCCCTAGGAAAAAGATTGTTTTAGGGTTTTTGAAAATTTGGCGATCGCCTAAGGGGATAATGGGGCTGGTTGGCT
AGGGTTTGAGAGACATCACC

Downstream 100 bases:

>100_bases
AGCTTTTCTGTATGATGAGGGATGGTCGAAATCTAGGGCAATACCAATCGTGAAAACTCCCCGCTGGCAACGGCGCAAAC
TGAGTCTCAGGCAACGGCAA

Product: type 4 prepilin peptidase

Products: NA

Alternate protein names: Leader peptidase; Prepilin peptidase; N-methyltransferase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MLALLQQSGLLAIAFIFLFIWGACFGSFLNVVVYRLPAGLSLAHPPSRCPHCGHQLGAQENIPVLGWLLLGGKCHWCKTP
IAARYPLVETLMGLLCVATVVQFGLTLEAIAAFTLLFWLVALALIDYDTFTLPNPLTQSGLVLGLLFQMGLGFQANGFPG
AIYGLMGGIGAAVLGLWLLDGIGVIGSAVLGQEAMGGGDPKLLAMIGAWLGWQNVLLTVILACALGTMIIGGAMGLGKHQ
RGQHLPFGPFLALGAIISLFWGDRLIELYLNAFLG

Sequences:

>Translated_275_residues
MLALLQQSGLLAIAFIFLFIWGACFGSFLNVVVYRLPAGLSLAHPPSRCPHCGHQLGAQENIPVLGWLLLGGKCHWCKTP
IAARYPLVETLMGLLCVATVVQFGLTLEAIAAFTLLFWLVALALIDYDTFTLPNPLTQSGLVLGLLFQMGLGFQANGFPG
AIYGLMGGIGAAVLGLWLLDGIGVIGSAVLGQEAMGGGDPKLLAMIGAWLGWQNVLLTVILACALGTMIIGGAMGLGKHQ
RGQHLPFGPFLALGAIISLFWGDRLIELYLNAFLG
>Mature_275_residues
MLALLQQSGLLAIAFIFLFIWGACFGSFLNVVVYRLPAGLSLAHPPSRCPHCGHQLGAQENIPVLGWLLLGGKCHWCKTP
IAARYPLVETLMGLLCVATVVQFGLTLEAIAAFTLLFWLVALALIDYDTFTLPNPLTQSGLVLGLLFQMGLGFQANGFPG
AIYGLMGGIGAAVLGLWLLDGIGVIGSAVLGQEAMGGGDPKLLAMIGAWLGWQNVLLTVILACALGTMIIGGAMGLGKHQ
RGQHLPFGPFLALGAIISLFWGDRLIELYLNAFLG

Specific function: Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue [H]

COG id: COG1989

COG function: function code NOU; Type II secretory pathway, prepilin signal peptidase PulO and related peptidases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A24 family [H]

Homologues:

Organism=Escherichia coli, GI87082194, Length=257, Percent_Identity=31.9066147859922, Blast_Score=107, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010627
- InterPro:   IPR014032
- InterPro:   IPR000045 [H]

Pfam domain/function: PF06750 DiS_P_DiS; PF01478 Peptidase_A24 [H]

EC number: =3.4.23.43 [H]

Molecular weight: Translated: 29041; Mature: 29041

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]