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The map label for this gene is ubiB [C]

Identifier: 170079197

GI number: 170079197

Start: 2729804

End: 2731471

Strand: Reverse

Name: ubiB [C]

Synonym: SYNPCC7002_A2603

Alternate gene names: 170079197

Gene position: 2731471-2729804 (Counterclockwise)

Preceding gene: 170079198

Following gene: 170079196

Centisome position: 90.81

GC content: 52.22

Gene sequence:

>1668_bases
GTGAAAACTCCCCGCTGGCAACGGCGCAAACTGAGTCTCAGGCAACGGCAACTGGAAATCTTTACCGTGGCCGCCCAGTT
TATCTTCCGGCTGGGCAAAGACCGACTCCCCGGTGGCAACCCTGCCCGCAAACGCCATCGCCAAGCCCGCTGGCTCGTGA
ATCACCTCCTGGATCTGGGGCCGACCTTCATCAAAATTGGCCAGGCCATGTCAACCCGCCCGGATCTATTTCCCATCGAA
TACATCGAGGAACTGAGCCAACTCCAAGACCGGGTGCCCCCATTTAAGGGTCAAGCGGCGATCGCCGTCATCGAGCAAGA
ATTTAACAAATCCATCTACGCCCTCTTTAAGGATTTTGAACTAGAGCCCCTCGCCTCCGCTAGCCTGGGCCAAGTGCACC
GGGCTACCCTCTACAGCGGCGAAGAAGTAGCCGTAAAAGTCCAGCGCCCCGGCCTGAGTCGTCTGTTCCAAGTGGATATG
CAAGTCCTCGAAAAACTTTTGCATTGGGCCAGTTATTTTTTAAAAGACCTCAAAAAATACAATCTCAATCAGATTTACCG
GGAATTTTTCGAGCTTCTCTACCAAGAAATTGACTACATCCATGAAGGGAAAAATGGCGATCATTTCCGGCAAAATTTCG
CCGACGATCAGCAAATTCTCGTGCCCAAGGTTTATTGGCAATACACCACCCGCAAGGTCTTAACCCTCGAATATTTACCG
GGCATTAAAATTGACGACCGGGCCGCCCTCGAAGCGAGCAATATTGACCCAGACCATGTGATCAGCCTCGGCATTTCTTC
TTACCTCAAACAACTGCTCCAGGATGGCTTTTTTCAGTCCGATCCCCACCCCGGCAATATGGCCGTCGATGCCACAGGGA
AGCTGATTTTCTATGATTTCGGCACGATGACCGAAGTCAAATCCATGGAAAAAACCCAGATGATGCGTACGTTTTTTGCG
GTGCTGCGCAAGGATACGGACGAGGTGGTCGAAACTCTGGTTTACATGGGCCTCATCGAGCCGATGGCAGATATGACCCC
GGTGAAACGGATGATCGCGTTTCTTTTGGATCGGTTTCGCGATCGCCCCATTGATCTCCAGGAATTTGAGCAGATTAGTA
ACGAGCTCTACCTGATGTTTGAGCAGCAACCGTTTCGTCTGCCGCCCCAAATGACTTTTATCATCAAGGCTCTCACCACC
CTCGATGGCATTGCCCGCGCCCTCGACCCCCAATACAATCTCATGGCGGCGGCCCAACCATTTATTCGTAGCTTGGCCGT
GAGTCACAAACCTGGGGAAAATCGCCTGGGGAGCCTCGCTCAACAGACTAAAGAATTTGTCCTGTACCAATTCCAGAAAC
CCAGCCGCACCGAAATGGCCATTAAACGCCTCGAATCACGCATCGAGTTAGGGGAACTGCAATTTCGCGTTAAATCCGTT
GAAGGCGATCGCCAATTGCGCCGAATCTACCTCGCGATCAAAACCATGATGTATGGCATCCTCTGGGGTTTTAGCAGTGT
GGTCGGTATTTTAGTCTGGAGTCAGGCGGCCTCTCTCTTCCTCATCGGGGCGATCGCCCTTACCGTATTTTTCTTTGGCC
TCCAAACCCTCCGCGCCCTCCTCCAACTGCTCATCCAAGAACGCCTCGATCACTTAATCCGTCGTTAA

Upstream 100 bases:

>100_bases
TTTTGGGGCGATCGCCTGATCGAACTCTACCTAAACGCGTTTTTGGGTTGAAGCTTTTCTGTATGATGAGGGATGGTCGA
AATCTAGGGCAATACCAATC

Downstream 100 bases:

>100_bases
GAGGCTCCCCCAATTTCAATTTAGACACCATTGGAACAGCACAAGGTAAAAATCCTGAAATTCCTTGCTATATCTAGGTT
TGAAACATATTAATGGGGTG

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MKTPRWQRRKLSLRQRQLEIFTVAAQFIFRLGKDRLPGGNPARKRHRQARWLVNHLLDLGPTFIKIGQAMSTRPDLFPIE
YIEELSQLQDRVPPFKGQAAIAVIEQEFNKSIYALFKDFELEPLASASLGQVHRATLYSGEEVAVKVQRPGLSRLFQVDM
QVLEKLLHWASYFLKDLKKYNLNQIYREFFELLYQEIDYIHEGKNGDHFRQNFADDQQILVPKVYWQYTTRKVLTLEYLP
GIKIDDRAALEASNIDPDHVISLGISSYLKQLLQDGFFQSDPHPGNMAVDATGKLIFYDFGTMTEVKSMEKTQMMRTFFA
VLRKDTDEVVETLVYMGLIEPMADMTPVKRMIAFLLDRFRDRPIDLQEFEQISNELYLMFEQQPFRLPPQMTFIIKALTT
LDGIARALDPQYNLMAAAQPFIRSLAVSHKPGENRLGSLAQQTKEFVLYQFQKPSRTEMAIKRLESRIELGELQFRVKSV
EGDRQLRRIYLAIKTMMYGILWGFSSVVGILVWSQAASLFLIGAIALTVFFFGLQTLRALLQLLIQERLDHLIRR

Sequences:

>Translated_555_residues
MKTPRWQRRKLSLRQRQLEIFTVAAQFIFRLGKDRLPGGNPARKRHRQARWLVNHLLDLGPTFIKIGQAMSTRPDLFPIE
YIEELSQLQDRVPPFKGQAAIAVIEQEFNKSIYALFKDFELEPLASASLGQVHRATLYSGEEVAVKVQRPGLSRLFQVDM
QVLEKLLHWASYFLKDLKKYNLNQIYREFFELLYQEIDYIHEGKNGDHFRQNFADDQQILVPKVYWQYTTRKVLTLEYLP
GIKIDDRAALEASNIDPDHVISLGISSYLKQLLQDGFFQSDPHPGNMAVDATGKLIFYDFGTMTEVKSMEKTQMMRTFFA
VLRKDTDEVVETLVYMGLIEPMADMTPVKRMIAFLLDRFRDRPIDLQEFEQISNELYLMFEQQPFRLPPQMTFIIKALTT
LDGIARALDPQYNLMAAAQPFIRSLAVSHKPGENRLGSLAQQTKEFVLYQFQKPSRTEMAIKRLESRIELGELQFRVKSV
EGDRQLRRIYLAIKTMMYGILWGFSSVVGILVWSQAASLFLIGAIALTVFFFGLQTLRALLQLLIQERLDHLIRR
>Mature_555_residues
MKTPRWQRRKLSLRQRQLEIFTVAAQFIFRLGKDRLPGGNPARKRHRQARWLVNHLLDLGPTFIKIGQAMSTRPDLFPIE
YIEELSQLQDRVPPFKGQAAIAVIEQEFNKSIYALFKDFELEPLASASLGQVHRATLYSGEEVAVKVQRPGLSRLFQVDM
QVLEKLLHWASYFLKDLKKYNLNQIYREFFELLYQEIDYIHEGKNGDHFRQNFADDQQILVPKVYWQYTTRKVLTLEYLP
GIKIDDRAALEASNIDPDHVISLGISSYLKQLLQDGFFQSDPHPGNMAVDATGKLIFYDFGTMTEVKSMEKTQMMRTFFA
VLRKDTDEVVETLVYMGLIEPMADMTPVKRMIAFLLDRFRDRPIDLQEFEQISNELYLMFEQQPFRLPPQMTFIIKALTT
LDGIARALDPQYNLMAAAQPFIRSLAVSHKPGENRLGSLAQQTKEFVLYQFQKPSRTEMAIKRLESRIELGELQFRVKSV
EGDRQLRRIYLAIKTMMYGILWGFSSVVGILVWSQAASLFLIGAIALTVFFFGLQTLRALLQLLIQERLDHLIRR

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=403, Percent_Identity=27.0471464019851, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI40254938, Length=458, Percent_Identity=27.9475982532751, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI217035081, Length=441, Percent_Identity=25.6235827664399, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI32261307, Length=317, Percent_Identity=25.5520504731861, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI27363457, Length=286, Percent_Identity=28.3216783216783, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI217416386, Length=231, Percent_Identity=29.8701298701299, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI34147522, Length=269, Percent_Identity=26.7657992565056, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI2367309, Length=375, Percent_Identity=31.7333333333333, Blast_Score=205, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17559152, Length=308, Percent_Identity=32.1428571428571, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI32565180, Length=191, Percent_Identity=33.5078534031414, Blast_Score=89, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6323282, Length=261, Percent_Identity=26.8199233716475, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321319, Length=254, Percent_Identity=28.740157480315, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6325148, Length=424, Percent_Identity=20.5188679245283, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24662575, Length=376, Percent_Identity=29.2553191489362, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI22024280, Length=268, Percent_Identity=30.2238805970149, Blast_Score=135, Evalue=8e-32,
Organism=Drosophila melanogaster, GI18859849, Length=262, Percent_Identity=29.0076335877863, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 64493; Mature: 64493

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]