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The map label for this gene is mutS [H]

Identifier: 170079175

GI number: 170079175

Start: 2699568

End: 2701967

Strand: Direct

Name: mutS [H]

Synonym: SYNPCC7002_A2581

Alternate gene names: 170079175

Gene position: 2699568-2701967 (Clockwise)

Preceding gene: 170079174

Following gene: 170079176

Centisome position: 89.74

GC content: 54.46

Gene sequence:

>2400_bases
TTGACTGAGATCCAAGCCGAAACCCTTAAACTTCTCGAATGGCAACGCCTGTGCCAACATTTATCGACCTTTGCCGCAAC
CAAGTTAGGGGCGATCGCCGCGCAGCATTTGGTTTTTCCCCAGAGCCAAGCAGACAGTGAGATTCTCCTGGCCCAAACCG
TCGAAATGCAGGCCTTAGATGGAGCGGTGGACAACGGCGTTTCCTTTGAGGGGATTGGCGATATCAGTGATGCTCTGGAA
CGGGCGACCGTGGGAGGACTGATCGCGGGGAAAGATTTATTGCTCATTGCCACTACCCTGGCCGGAGTGCGTCGTTTGCG
GCGCTTGGTGGAAAATGCGGAGTTAGAACTCTCCCAATTGACGCGCCTGGTGGAGCAGGTGCGCACCTACCCGGAATTGG
AACAAGATATTCACCATTGCATCGATGACCGGGGAGATGTTACAGACCGAGCTAGCCCAAAGCTCGAAGGAATTCGCGTC
AAAATTAAAGGGGCCAGGGAGCAGATTTACCAAACCTTGCAGCGGATCATGCAGCGGCACAGTGGCTCGATCCAGGAAGC
GGTCATTACCCAACGGGGCGATCGCTTTGTGTTACCCGTTAAGGCAGGGCAAAAGGAACAAATTCCTGGCATCGTCCACG
ATATTTCCAGCACGGGCTCGACCCTTTACATCGAACCCAAGGGGATTGTGGAGCTGGGTAATCGCCTCCGCCAGGCTGTG
AAACAAGAGGAGCGGGAAATTGAAATTGTCCTGCGTCAGCTCACCGAAAAAGTGGCCGAGGTAGTCGAGGATCTCGAAAA
ACTCCTGGCGATCGCCACCACCCTCGATCTCGCCATGACCCGCGCTCGCTATAGTCTTTGGCTCGATGGGCATCCGCCCA
AATTTATCGCCCCCGATCAACCGACAATACTGCGGCAGTTGCGCCATCCTTTGCTGGTGTGGCAGGAGAAACAAGAAGAA
AGCCTGGAAGTTATCCCGATCAATGTGCAAATTCGCCCAGAAATCCGCGTCGTGGCGATCACGGGCCCCAATACTGGCGG
CAAAACTGTCACCTTAAAGACTCTGGGAATGGCCGCGCTCATGGCGAAGGTGGGCCTTTTTATCCCGGCGATCGCCCCGG
TGGAAATCCCTTGGTTTGACCAGGTTTTAGCTGATATCGGCGATGAACAATCCCTCCAGCAGAGTTTATCGACTTTTTCT
GGCCATATTCGCCGTGTAGGTCGGATTATTGAAGCTTTAGACCAGGAGAGTCAGAATAATCTTGTGCTCCTCGATGAGGT
GGGGGCCGGCACCGATCCCACCGAAGGCAGCGCCCTGGCGATCGCCCTGTTGAAATATTTGGCAGACCAGACCCAGCTCA
CGGTGGCCACCACCCACTACGGGGAACTGAAGGCCCTAAAGTACGAGGATGAGCGCTTTGAAAATGCCTCGGTCGAATTT
GATGAATATTCCCTCCGGCCCACCTACAAGTTGCTCTGGGGGATTCCGGGACGTTCCAATGCCTTGGCGATCGCCCAGCG
TTTGGGCCTAGATGCGGAGATTGTGGAAACAGCCCAGGATCTGTTGGGGAATACTAATACCAATGTCAACGAGGTGATCG
CCGCCCTCGAAGCCCAGCGCCGGGAACAGGAACAAAAAGCCAAGGAAGCCGAAGCTCTCCTCAAACAGACCGAACGGTTC
TATACGGAAGTTTCCAGTAAAGCCGCCGATCTCCAACGCCGGGAAGCTGAACTCAAACTCGCCCAAGACCAACAGGTACA
AGCGGCGATCGCCGAAGCTAAAGCCGAGATTGCCCAGGTAATTCGCACCTTACAAAAGGGCCAACCCACCGCCCAAAAAG
CCCAGGTTGCCACCGAAGCCCTGGGGGACATTGCCGCCAGCAAAATGAGTCAACCCAAACGGAAAAAACCGGGTTATCAA
CCGCAATTGGGGGAAAAAATTCGCATTTCTAAGCTGGGACAAACCGCCGAGGTCATTGAACTAGACCCTGACAATAAAAC
CCTCGTCGCCCGTTTTGGGGTGATGAAAATGTCCCTCGATTGGACAGAAATTGAATCGCTCCAGGGCCAGAAAGTCGAGG
CAGAGCCCAAGCCAAAAACCCCGAAAAAACAAGCGCCACCCAAAGCAAAAACACCTGAGACCGTGACGGTGCGCACCACC
CGCAATACCATCGATATCCGGGGACAACGGATGCACCAAGCAGAAAGTAGCCTCGAACAGGCGATCGCCAATGCCACTGC
TGCGGGTTCCCAGGTCATTTGGATTATCCACGGCAAAGGTACCGGCAAGCTCCGGGAAGGCGTCCATGAATTTTTGAAAT
ACCATCCCCAAATTCAGCGCTACGAACTCGCCGATCAAAAAGAAGGGGGAGCTGGCGTCACCCTGGCCTATTTTTCCTAA

Upstream 100 bases:

>100_bases
GGTACAGATCAGCCATTGGAGCCTCCCCATTAAGGGCGATCGCCTTGCTCAATTCATTTTCTATATAATTGAACTCTGCC
GTATTTCCTCTTAACTGTCC

Downstream 100 bases:

>100_bases
GAAGGCCGCATACTACAATATTTCCCTGGGAATCCTTTTGTACCAGAACACCACTCTAGCCCCAGGGACTCAATGCTCAA
GCTCTTTAAACGCTACGAAA

Product: recombination and DNA strand exchange inhibitor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 799; Mature: 798

Protein sequence:

>799_residues
MTEIQAETLKLLEWQRLCQHLSTFAATKLGAIAAQHLVFPQSQADSEILLAQTVEMQALDGAVDNGVSFEGIGDISDALE
RATVGGLIAGKDLLLIATTLAGVRRLRRLVENAELELSQLTRLVEQVRTYPELEQDIHHCIDDRGDVTDRASPKLEGIRV
KIKGAREQIYQTLQRIMQRHSGSIQEAVITQRGDRFVLPVKAGQKEQIPGIVHDISSTGSTLYIEPKGIVELGNRLRQAV
KQEEREIEIVLRQLTEKVAEVVEDLEKLLAIATTLDLAMTRARYSLWLDGHPPKFIAPDQPTILRQLRHPLLVWQEKQEE
SLEVIPINVQIRPEIRVVAITGPNTGGKTVTLKTLGMAALMAKVGLFIPAIAPVEIPWFDQVLADIGDEQSLQQSLSTFS
GHIRRVGRIIEALDQESQNNLVLLDEVGAGTDPTEGSALAIALLKYLADQTQLTVATTHYGELKALKYEDERFENASVEF
DEYSLRPTYKLLWGIPGRSNALAIAQRLGLDAEIVETAQDLLGNTNTNVNEVIAALEAQRREQEQKAKEAEALLKQTERF
YTEVSSKAADLQRREAELKLAQDQQVQAAIAEAKAEIAQVIRTLQKGQPTAQKAQVATEALGDIAASKMSQPKRKKPGYQ
PQLGEKIRISKLGQTAEVIELDPDNKTLVARFGVMKMSLDWTEIESLQGQKVEAEPKPKTPKKQAPPKAKTPETVTVRTT
RNTIDIRGQRMHQAESSLEQAIANATAAGSQVIWIIHGKGTGKLREGVHEFLKYHPQIQRYELADQKEGGAGVTLAYFS

Sequences:

>Translated_799_residues
MTEIQAETLKLLEWQRLCQHLSTFAATKLGAIAAQHLVFPQSQADSEILLAQTVEMQALDGAVDNGVSFEGIGDISDALE
RATVGGLIAGKDLLLIATTLAGVRRLRRLVENAELELSQLTRLVEQVRTYPELEQDIHHCIDDRGDVTDRASPKLEGIRV
KIKGAREQIYQTLQRIMQRHSGSIQEAVITQRGDRFVLPVKAGQKEQIPGIVHDISSTGSTLYIEPKGIVELGNRLRQAV
KQEEREIEIVLRQLTEKVAEVVEDLEKLLAIATTLDLAMTRARYSLWLDGHPPKFIAPDQPTILRQLRHPLLVWQEKQEE
SLEVIPINVQIRPEIRVVAITGPNTGGKTVTLKTLGMAALMAKVGLFIPAIAPVEIPWFDQVLADIGDEQSLQQSLSTFS
GHIRRVGRIIEALDQESQNNLVLLDEVGAGTDPTEGSALAIALLKYLADQTQLTVATTHYGELKALKYEDERFENASVEF
DEYSLRPTYKLLWGIPGRSNALAIAQRLGLDAEIVETAQDLLGNTNTNVNEVIAALEAQRREQEQKAKEAEALLKQTERF
YTEVSSKAADLQRREAELKLAQDQQVQAAIAEAKAEIAQVIRTLQKGQPTAQKAQVATEALGDIAASKMSQPKRKKPGYQ
PQLGEKIRISKLGQTAEVIELDPDNKTLVARFGVMKMSLDWTEIESLQGQKVEAEPKPKTPKKQAPPKAKTPETVTVRTT
RNTIDIRGQRMHQAESSLEQAIANATAAGSQVIWIIHGKGTGKLREGVHEFLKYHPQIQRYELADQKEGGAGVTLAYFS
>Mature_798_residues
TEIQAETLKLLEWQRLCQHLSTFAATKLGAIAAQHLVFPQSQADSEILLAQTVEMQALDGAVDNGVSFEGIGDISDALER
ATVGGLIAGKDLLLIATTLAGVRRLRRLVENAELELSQLTRLVEQVRTYPELEQDIHHCIDDRGDVTDRASPKLEGIRVK
IKGAREQIYQTLQRIMQRHSGSIQEAVITQRGDRFVLPVKAGQKEQIPGIVHDISSTGSTLYIEPKGIVELGNRLRQAVK
QEEREIEIVLRQLTEKVAEVVEDLEKLLAIATTLDLAMTRARYSLWLDGHPPKFIAPDQPTILRQLRHPLLVWQEKQEES
LEVIPINVQIRPEIRVVAITGPNTGGKTVTLKTLGMAALMAKVGLFIPAIAPVEIPWFDQVLADIGDEQSLQQSLSTFSG
HIRRVGRIIEALDQESQNNLVLLDEVGAGTDPTEGSALAIALLKYLADQTQLTVATTHYGELKALKYEDERFENASVEFD
EYSLRPTYKLLWGIPGRSNALAIAQRLGLDAEIVETAQDLLGNTNTNVNEVIAALEAQRREQEQKAKEAEALLKQTERFY
TEVSSKAADLQRREAELKLAQDQQVQAAIAEAKAEIAQVIRTLQKGQPTAQKAQVATEALGDIAASKMSQPKRKKPGYQP
QLGEKIRISKLGQTAEVIELDPDNKTLVARFGVMKMSLDWTEIESLQGQKVEAEPKPKTPKKQAPPKAKTPETVTVRTTR
NTIDIRGQRMHQAESSLEQAIANATAAGSQVIWIIHGKGTGKLREGVHEFLKYHPQIQRYELADQKEGGAGVTLAYFS

Specific function: This Protein Is Involved In The Repair Of Mismatches In DNA. It Is Possible That It Carries Out The Mismatch Recognition Step. This Protein Has A Weak Atpase Activity. [C]

COG id: COG1193

COG function: function code L; Mismatch repair ATPase (MutS family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Smr domain [H]

Homologues:

Organism=Homo sapiens, GI284813531, Length=409, Percent_Identity=26.4058679706601, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI36949366, Length=366, Percent_Identity=23.224043715847, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI4557761, Length=280, Percent_Identity=26.0714285714286, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI4504191, Length=246, Percent_Identity=28.4552845528455, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI26638666, Length=192, Percent_Identity=31.25, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI4505253, Length=192, Percent_Identity=31.25, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI26638664, Length=192, Percent_Identity=30.7291666666667, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI262231786, Length=192, Percent_Identity=30.7291666666667, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1789089, Length=276, Percent_Identity=30.0724637681159, Blast_Score=100, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17534743, Length=371, Percent_Identity=24.2587601078167, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17508445, Length=280, Percent_Identity=24.2857142857143, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17508447, Length=238, Percent_Identity=26.890756302521, Blast_Score=77, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17539736, Length=220, Percent_Identity=26.8181818181818, Blast_Score=73, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319935, Length=285, Percent_Identity=28.7719298245614, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6321912, Length=333, Percent_Identity=24.6246246246246, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324482, Length=366, Percent_Identity=24.8633879781421, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320302, Length=222, Percent_Identity=28.3783783783784, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6321109, Length=407, Percent_Identity=22.3587223587224, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6320047, Length=209, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24584320, Length=262, Percent_Identity=27.4809160305344, Blast_Score=97, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24664545, Length=289, Percent_Identity=26.2975778546713, Blast_Score=86, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005747
- InterPro:   IPR000432
- InterPro:   IPR007696
- InterPro:   IPR002625 [H]

Pfam domain/function: PF00488 MutS_V; PF01713 Smr [H]

EC number: NA

Molecular weight: Translated: 88407; Mature: 88276

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50828 SMR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEIQAETLKLLEWQRLCQHLSTFAATKLGAIAAQHLVFPQSQADSEILLAQTVEMQALD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHC
GAVDNGVSFEGIGDISDALERATVGGLIAGKDLLLIATTLAGVRRLRRLVENAELELSQL
CHHCCCCCCCCCCCHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
TRLVEQVRTYPELEQDIHHCIDDRGDVTDRASPKLEGIRVKIKGAREQIYQTLQRIMQRH
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHH
SGSIQEAVITQRGDRFVLPVKAGQKEQIPGIVHDISSTGSTLYIEPKGIVELGNRLRQAV
CCCHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHCCCCCEEEECCCHHHHHHHHHHHHH
KQEEREIEIVLRQLTEKVAEVVEDLEKLLAIATTLDLAMTRARYSLWLDGHPPKFIAPDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCC
PTILRQLRHPLLVWQEKQEESLEVIPINVQIRPEIRVVAITGPNTGGKTVTLKTLGMAAL
HHHHHHHCCCCEEECCCCCCCCEEEEEEEEECCCEEEEEEECCCCCCCEEEEHHHHHHHH
MAKVGLFIPAIAPVEIPWFDQVLADIGDEQSLQQSLSTFSGHIRRVGRIIEALDQESQNN
HHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LVLLDEVGAGTDPTEGSALAIALLKYLADQTQLTVATTHYGELKALKYEDERFENASVEF
EEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECHHHCCCCCCCC
DEYSLRPTYKLLWGIPGRSNALAIAQRLGLDAEIVETAQDLLGNTNTNVNEVIAALEAQR
CCCCCCCCCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
REQEQKAKEAEALLKQTERFYTEVSSKAADLQRREAELKLAQDQQVQAAIAEAKAEIAQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRTLQKGQPTAQKAQVATEALGDIAASKMSQPKRKKPGYQPQLGEKIRISKLGQTAEVIE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCEEEHHHCCCCEEEEE
LDPDNKTLVARFGVMKMSLDWTEIESLQGQKVEAEPKPKTPKKQAPPKAKTPETVTVRTT
ECCCCCEEEEEECCEEEECCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
RNTIDIRGQRMHQAESSLEQAIANATAAGSQVIWIIHGKGTGKLREGVHEFLKYHPQIQR
CCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHH
YELADQKEGGAGVTLAYFS
HHCCCCCCCCCCEEEEEEC
>Mature Secondary Structure 
TEIQAETLKLLEWQRLCQHLSTFAATKLGAIAAQHLVFPQSQADSEILLAQTVEMQALD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHC
GAVDNGVSFEGIGDISDALERATVGGLIAGKDLLLIATTLAGVRRLRRLVENAELELSQL
CHHCCCCCCCCCCCHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
TRLVEQVRTYPELEQDIHHCIDDRGDVTDRASPKLEGIRVKIKGAREQIYQTLQRIMQRH
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHH
SGSIQEAVITQRGDRFVLPVKAGQKEQIPGIVHDISSTGSTLYIEPKGIVELGNRLRQAV
CCCHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHCCCCCEEEECCCHHHHHHHHHHHHH
KQEEREIEIVLRQLTEKVAEVVEDLEKLLAIATTLDLAMTRARYSLWLDGHPPKFIAPDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCC
PTILRQLRHPLLVWQEKQEESLEVIPINVQIRPEIRVVAITGPNTGGKTVTLKTLGMAAL
HHHHHHHCCCCEEECCCCCCCCEEEEEEEEECCCEEEEEEECCCCCCCEEEEHHHHHHHH
MAKVGLFIPAIAPVEIPWFDQVLADIGDEQSLQQSLSTFSGHIRRVGRIIEALDQESQNN
HHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LVLLDEVGAGTDPTEGSALAIALLKYLADQTQLTVATTHYGELKALKYEDERFENASVEF
EEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECHHHCCCCCCCC
DEYSLRPTYKLLWGIPGRSNALAIAQRLGLDAEIVETAQDLLGNTNTNVNEVIAALEAQR
CCCCCCCCCEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
REQEQKAKEAEALLKQTERFYTEVSSKAADLQRREAELKLAQDQQVQAAIAEAKAEIAQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRTLQKGQPTAQKAQVATEALGDIAASKMSQPKRKKPGYQPQLGEKIRISKLGQTAEVIE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCEEEHHHCCCCEEEEE
LDPDNKTLVARFGVMKMSLDWTEIESLQGQKVEAEPKPKTPKKQAPPKAKTPETVTVRTT
ECCCCCEEEEEECCEEEECCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
RNTIDIRGQRMHQAESSLEQAIANATAAGSQVIWIIHGKGTGKLREGVHEFLKYHPQIQR
CCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHH
YELADQKEGGAGVTLAYFS
HHCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]