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The map label for this gene is hemN [H]

Identifier: 170078594

GI number: 170078594

Start: 2071309

End: 2072706

Strand: Reverse

Name: hemN [H]

Synonym: SYNPCC7002_A1990

Alternate gene names: 170078594

Gene position: 2072706-2071309 (Counterclockwise)

Preceding gene: 170078595

Following gene: 170078593

Centisome position: 68.91

GC content: 50.0

Gene sequence:

>1398_bases
ATGAATTTAGCCTGTCAAAATGTCCGCTTTGATGGACAGCTCCTCCAAAAATATAATCAAGCGGTTCCCCGCTATACCAG
TTACCCCCCCGCAACGGAATTAACCCCCGATTTTGATGGGGATCTTTTCCGCCAGGCGATCGCCATGGGGAATTATAAAA
AAACGCCCCTTTCCCTCTACTGCCACATTCCTTTTTGTGAAAAGCCCTGCTATTTCTGTGGCTGCAATACGATCATTACC
CAGTACAAACCCGCCGCCGCTACCTATCTGGACTACCTGATTCGTCACATTCAACAGGTTGCCCCCCTCGTCCAAGGCGA
TCGCCTGGTGCAACAACTCCACTGGGGTGGCGGCACACCCAATTATTTAAACTTGGAGCAAGTGACGCGTTTGTGGCAAA
CCCTCCAGGACAATTTTCAATTTGCGCCCGATGCGGAGATTTCCATCGAGATCAACCCCTGCGAGGTGAGTCGCGAGTAT
ATTTTTGTCTTGCATCAACTGGGTTTTAAGCGGATCAGCTTTGGCATTCAGGATTTTAATCCCCAGGTACAAGCGGCGGT
CAATCGCATCCAGCCGGAAGAAAAACTCTTTGAGGTGATGGCCTGGATCCGCGAGGCAGGTTTTGAGAGCGTCAACGTAG
ATTTAATTTACGGCCTGCCCTACCAAACCCTGGCGACGTTCACGGAAACGGTGGAAAAAACAATCCAACTCAACCCCGAC
CGGATCGCTGTCTTTAGCTTTGCCTATGTGCCCTGGCTGAAACCTCTGCAAAAACGGATGCCCGAAGCGGCGATGCCCCC
CACCGCCGAAAAGCTCGAAATCCTCAAGATGACCATCGCTAATCTGACCTACCACGGTTATGTGTTCATCGGGATGGATC
ATTTTGCCAAGCCCAACGATGAATTGGCGATCGCCCAACAGGCGGGGGAACTGCACCGGAATTTCCAGGGCTACACCACG
AAGCCGGAATCGGATCTTTTGGGATTTGGCATGACATCGATCAGTATGCTCCAGAACGTTTACGCCCAGAACCATAAAAA
GCTCAAAGATTTTTATGCTGCCATTGATCAACAAGTTCTTCCCATCGAAAAGGGCGTTCAACTCAGCCAAGATGACCTGA
TTCGTCGCACTGTGATCATGGAATTGATGTGTCAGTTCCAACTGTCGGCCCCCAACCTCGAAAACAAATATCACCTGGGC
TTTGATTTAGACTTTAACGATTATTTCCAAGCCGAATTGAGTGCCCTAAACGATTTGGAAGCCGATGGTCTAATTCATCG
TTCTGGAGATGGTTTCCAGGTGACGCCCAGTGGTCGGCTGCTGATCCGCAATATTGCGGCGGTGTTTGATACCTACCTGC
AACACAAAACGGAGAAAACCTTCTCCAAGGCGATTTAG

Upstream 100 bases:

>100_bases
CACTTTTGTGATGTGGTTTGAAAGCTTAACGTCGCCCTGAAGTGGAGGTGCCGGGGGATTTTTTTGAAAAATCAACTGCT
TTCATTAATCTCTTTTTCCC

Downstream 100 bases:

>100_bases
CGATCGCCACCAGTTCCCTGGGGGAGGATCAACCCACCGATATTCCCCTTTGTCTTGTTCTATTGTTTGAGAATTCATGA
CCCAATCTGTGCAACACCCC

Product: coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MNLACQNVRFDGQLLQKYNQAVPRYTSYPPATELTPDFDGDLFRQAIAMGNYKKTPLSLYCHIPFCEKPCYFCGCNTIIT
QYKPAAATYLDYLIRHIQQVAPLVQGDRLVQQLHWGGGTPNYLNLEQVTRLWQTLQDNFQFAPDAEISIEINPCEVSREY
IFVLHQLGFKRISFGIQDFNPQVQAAVNRIQPEEKLFEVMAWIREAGFESVNVDLIYGLPYQTLATFTETVEKTIQLNPD
RIAVFSFAYVPWLKPLQKRMPEAAMPPTAEKLEILKMTIANLTYHGYVFIGMDHFAKPNDELAIAQQAGELHRNFQGYTT
KPESDLLGFGMTSISMLQNVYAQNHKKLKDFYAAIDQQVLPIEKGVQLSQDDLIRRTVIMELMCQFQLSAPNLENKYHLG
FDLDFNDYFQAELSALNDLEADGLIHRSGDGFQVTPSGRLLIRNIAAVFDTYLQHKTEKTFSKAI

Sequences:

>Translated_465_residues
MNLACQNVRFDGQLLQKYNQAVPRYTSYPPATELTPDFDGDLFRQAIAMGNYKKTPLSLYCHIPFCEKPCYFCGCNTIIT
QYKPAAATYLDYLIRHIQQVAPLVQGDRLVQQLHWGGGTPNYLNLEQVTRLWQTLQDNFQFAPDAEISIEINPCEVSREY
IFVLHQLGFKRISFGIQDFNPQVQAAVNRIQPEEKLFEVMAWIREAGFESVNVDLIYGLPYQTLATFTETVEKTIQLNPD
RIAVFSFAYVPWLKPLQKRMPEAAMPPTAEKLEILKMTIANLTYHGYVFIGMDHFAKPNDELAIAQQAGELHRNFQGYTT
KPESDLLGFGMTSISMLQNVYAQNHKKLKDFYAAIDQQVLPIEKGVQLSQDDLIRRTVIMELMCQFQLSAPNLENKYHLG
FDLDFNDYFQAELSALNDLEADGLIHRSGDGFQVTPSGRLLIRNIAAVFDTYLQHKTEKTFSKAI
>Mature_465_residues
MNLACQNVRFDGQLLQKYNQAVPRYTSYPPATELTPDFDGDLFRQAIAMGNYKKTPLSLYCHIPFCEKPCYFCGCNTIIT
QYKPAAATYLDYLIRHIQQVAPLVQGDRLVQQLHWGGGTPNYLNLEQVTRLWQTLQDNFQFAPDAEISIEINPCEVSREY
IFVLHQLGFKRISFGIQDFNPQVQAAVNRIQPEEKLFEVMAWIREAGFESVNVDLIYGLPYQTLATFTETVEKTIQLNPD
RIAVFSFAYVPWLKPLQKRMPEAAMPPTAEKLEILKMTIANLTYHGYVFIGMDHFAKPNDELAIAQQAGELHRNFQGYTT
KPESDLLGFGMTSISMLQNVYAQNHKKLKDFYAAIDQQVLPIEKGVQLSQDDLIRRTVIMELMCQFQLSAPNLENKYHLG
FDLDFNDYFQAELSALNDLEADGLIHRSGDGFQVTPSGRLLIRNIAAVFDTYLQHKTEKTFSKAI

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=191, Percent_Identity=24.0837696335079, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI87082341, Length=464, Percent_Identity=50.4310344827586, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI1789325, Length=247, Percent_Identity=28.3400809716599, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004558
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 53176; Mature: 53176

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLACQNVRFDGQLLQKYNQAVPRYTSYPPATELTPDFDGDLFRQAIAMGNYKKTPLSLY
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEE
CHIPFCEKPCYFCGCNTIITQYKPAAATYLDYLIRHIQQVAPLVQGDRLVQQLHWGGGTP
EECCCCCCCCEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NYLNLEQVTRLWQTLQDNFQFAPDAEISIEINPCEVSREYIFVLHQLGFKRISFGIQDFN
CEECHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCHHHHHCCHHCCC
PQVQAAVNRIQPEEKLFEVMAWIREAGFESVNVDLIYGLPYQTLATFTETVEKTIQLNPD
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCEECEEEEECCCHHHHHHHHHHHHHHHCCCCC
RIAVFSFAYVPWLKPLQKRMPEAAMPPTAEKLEILKMTIANLTYHGYVFIGMDHFAKPND
EEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEECCEEEEEEHHCCCCCC
ELAIAQQAGELHRNFQGYTTKPESDLLGFGMTSISMLQNVYAQNHKKLKDFYAAIDQQVL
CCHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PIEKGVQLSQDDLIRRTVIMELMCQFQLSAPNLENKYHLGFDLDFNDYFQAELSALNDLE
CHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCC
ADGLIHRSGDGFQVTPSGRLLIRNIAAVFDTYLQHKTEKTFSKAI
CCCEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLACQNVRFDGQLLQKYNQAVPRYTSYPPATELTPDFDGDLFRQAIAMGNYKKTPLSLY
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEE
CHIPFCEKPCYFCGCNTIITQYKPAAATYLDYLIRHIQQVAPLVQGDRLVQQLHWGGGTP
EECCCCCCCCEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NYLNLEQVTRLWQTLQDNFQFAPDAEISIEINPCEVSREYIFVLHQLGFKRISFGIQDFN
CEECHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCHHHHHCCHHCCC
PQVQAAVNRIQPEEKLFEVMAWIREAGFESVNVDLIYGLPYQTLATFTETVEKTIQLNPD
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCEECEEEEECCCHHHHHHHHHHHHHHHCCCCC
RIAVFSFAYVPWLKPLQKRMPEAAMPPTAEKLEILKMTIANLTYHGYVFIGMDHFAKPND
EEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEECCEEEEEEHHCCCCCC
ELAIAQQAGELHRNFQGYTTKPESDLLGFGMTSISMLQNVYAQNHKKLKDFYAAIDQQVL
CCHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PIEKGVQLSQDDLIRRTVIMELMCQFQLSAPNLENKYHLGFDLDFNDYFQAELSALNDLE
CHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCC
ADGLIHRSGDGFQVTPSGRLLIRNIAAVFDTYLQHKTEKTFSKAI
CCCEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]