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The map label for this gene is moaE [H]

Identifier: 170078297

GI number: 170078297

Start: 1773586

End: 1774044

Strand: Direct

Name: moaE [H]

Synonym: SYNPCC7002_A1690

Alternate gene names: 170078297

Gene position: 1773586-1774044 (Clockwise)

Preceding gene: 170078293

Following gene: 170078298

Centisome position: 58.96

GC content: 56.21

Gene sequence:

>459_bases
ATGCGCGTCCCCACCTATCCCCACGATCAGTTTGCGATCGCCTTTGCTCCCCTCTCCTTTGATACGGTGTACCGTCTCGC
CGAAGACCCCGGTAGTGGGGCCGTGGTGGTGATGAGCGGTACCGTCCGGAATCGCAGCGATGGCAAAGCTGTTCATTATC
TCGAATACCAAGCCTACGAACCAATGGCGATCGCCATTTTTCAGCAGATCGCCCACGACATCCGCCAACAATGGCCCGAC
ACAAATCGGGTCGTGATTCACCACCGCATCGGCAAGCTAGAAATTGGTGAAATTAGCGTCCTCGTCGCCGCCAGTTGTCC
CCACCGGGCTGAAGCCTTTGCGGCCTGTCGCTATGGCATCGATACGATCAAACACAATGCCCCGATTTGGAAAAAGGAAT
TTTTTGCCGGAGGCACAAGCGAATGGGTGCAGGGTTGCCGCACTGCTGAGGGCTGTTAA

Upstream 100 bases:

>100_bases
GGATGATCAGGCACAAAAACCCGGAGTTGCGAAGCCATAGACGTTTTGCATCAAGAAAGAACCGTCCTTTAGACTAGCAT
AAGCTTTTAGATGAAACCCG

Downstream 100 bases:

>100_bases
TCCTTCCTGACAGATGCCCCCGTAATCGTTTGAAGAAAGTTTAGGCGATCGCGTATGATGGGACGCTGGTTCACATAAGG
AAATCGCGGATATGGCACGT

Product: molybdopterin converting factor, chain 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MRVPTYPHDQFAIAFAPLSFDTVYRLAEDPGSGAVVVMSGTVRNRSDGKAVHYLEYQAYEPMAIAIFQQIAHDIRQQWPD
TNRVVIHHRIGKLEIGEISVLVAASCPHRAEAFAACRYGIDTIKHNAPIWKKEFFAGGTSEWVQGCRTAEGC

Sequences:

>Translated_152_residues
MRVPTYPHDQFAIAFAPLSFDTVYRLAEDPGSGAVVVMSGTVRNRSDGKAVHYLEYQAYEPMAIAIFQQIAHDIRQQWPD
TNRVVIHHRIGKLEIGEISVLVAASCPHRAEAFAACRYGIDTIKHNAPIWKKEFFAGGTSEWVQGCRTAEGC
>Mature_152_residues
MRVPTYPHDQFAIAFAPLSFDTVYRLAEDPGSGAVVVMSGTVRNRSDGKAVHYLEYQAYEPMAIAIFQQIAHDIRQQWPD
TNRVVIHHRIGKLEIGEISVLVAASCPHRAEAFAACRYGIDTIKHNAPIWKKEFFAGGTSEWVQGCRTAEGC

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=123, Percent_Identity=42.2764227642276, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1787003, Length=119, Percent_Identity=37.8151260504202, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17509279, Length=135, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356259, Length=138, Percent_Identity=39.1304347826087, Blast_Score=115, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16947; Mature: 16947

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVPTYPHDQFAIAFAPLSFDTVYRLAEDPGSGAVVVMSGTVRNRSDGKAVHYLEYQAYE
CCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCC
PMAIAIFQQIAHDIRQQWPDTNRVVIHHRIGKLEIGEISVLVAASCPHRAEAFAACRYGI
CHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEECCEEEEEEECCCCHHHHHHHHHHHH
DTIKHNAPIWKKEFFAGGTSEWVQGCRTAEGC
HHHHCCCCCCHHHHCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MRVPTYPHDQFAIAFAPLSFDTVYRLAEDPGSGAVVVMSGTVRNRSDGKAVHYLEYQAYE
CCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCC
PMAIAIFQQIAHDIRQQWPDTNRVVIHHRIGKLEIGEISVLVAASCPHRAEAFAACRYGI
CHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEECCEEEEEEECCCCHHHHHHHHHHHH
DTIKHNAPIWKKEFFAGGTSEWVQGCRTAEGC
HHHHCCCCCCHHHHCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]