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The map label for this gene is rsmH

Identifier: 170078284

GI number: 170078284

Start: 1760232

End: 1761104

Strand: Direct

Name: rsmH

Synonym: SYNPCC7002_A1677

Alternate gene names: 170078284

Gene position: 1760232-1761104 (Clockwise)

Preceding gene: 170078283

Following gene: 170078285

Centisome position: 58.52

GC content: 45.59

Gene sequence:

>873_bases
ATGGCGGCAGAGTTTAAACATATTTCGGTATTGAAAGAAGAGTTGGTAGCAGGTTTGGGAGTGAAACCGGAAGGCCATTA
CTTAGATGTGACCCTGGGTGGTGGTGGCCATACAGAATTGATTTTGCAGCAATATCCCGATGTGCGGGTGACGGGGGTAG
ACCGAGATAGCCAGGCGATCGCCGCAGCGTCAGAACGATTAAAATCCTTTGGCGATCGCTTCCGGGCGGTGCGGTCAAAT
TTTGGTGAATATCAGCCCCAGGGAGAAAAATTTGACGGGATTATCGCTGATCTTGGGGTGAGTTCGGTGCAATTTGATCA
AGGCGATCGCGGCTTTAGTTTTCGTTTTGATGCCCCCTTGGATATGCGCATGGATCAACAACAGACATTAACAGCGGCGG
ATATTGTCAACACCTATGAGGAAAAGGCGTTGGCGAATTTGTTCTATGAGTATGGTGATGAACGATTGTCACGACAAATT
GCGAAAAAAATAGTCATGAAACGCCCGATTCAGACAACTAAAGAACTAGAAGAAATTGTGTTTTATACCTATCATCCCAA
GGCTAGAAAAGTGAAAATTCATCCGGCAACAAGGGTCTTTCAAGCATTACGTATTGCCGTCAATGGTGAACTCGATGCAC
TGCAATATCTATTAGTCAATGCCCCCCAATGGCTTAAGCCCCAAGGCCGATTAGGGATTATTAGTTTCCATAGTTTAGAA
GATCGTCTCGTCAAAAATGCCTTTCGGCAGCGGGACATTTGGCGGATTCTAACAAAAAAACCAATGGTTGCCAGTGAAAC
GGAAATCAACCAAAATCCTCGGGCACGATCCGCAAAATTACGCTTTGCCGAGTTGAAAGAAACAACAGAATAG

Upstream 100 bases:

>100_bases
GGCTACGAAATTATGGGGATGTAATGTCCTGGTTTAGTGGCGATCGCCCTTGGGTTCCCCCTCAGTGATAGGGGGATTTT
GTTTTTTATTGGATAGGTTC

Downstream 100 bases:

>100_bases
GCGAGCTAATTAATTCAATAAGATAGAAAAAGCTATCACACAAGTCGGTTTTGTACATTAAGTTTGATCGTCATTAAAAA
TGAGACAAATTCTAGAAGGA

Product: S-adenosyl-methyltransferase

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MAAEFKHISVLKEELVAGLGVKPEGHYLDVTLGGGGHTELILQQYPDVRVTGVDRDSQAIAAASERLKSFGDRFRAVRSN
FGEYQPQGEKFDGIIADLGVSSVQFDQGDRGFSFRFDAPLDMRMDQQQTLTAADIVNTYEEKALANLFYEYGDERLSRQI
AKKIVMKRPIQTTKELEEIVFYTYHPKARKVKIHPATRVFQALRIAVNGELDALQYLLVNAPQWLKPQGRLGIISFHSLE
DRLVKNAFRQRDIWRILTKKPMVASETEINQNPRARSAKLRFAELKETTE

Sequences:

>Translated_290_residues
MAAEFKHISVLKEELVAGLGVKPEGHYLDVTLGGGGHTELILQQYPDVRVTGVDRDSQAIAAASERLKSFGDRFRAVRSN
FGEYQPQGEKFDGIIADLGVSSVQFDQGDRGFSFRFDAPLDMRMDQQQTLTAADIVNTYEEKALANLFYEYGDERLSRQI
AKKIVMKRPIQTTKELEEIVFYTYHPKARKVKIHPATRVFQALRIAVNGELDALQYLLVNAPQWLKPQGRLGIISFHSLE
DRLVKNAFRQRDIWRILTKKPMVASETEINQNPRARSAKLRFAELKETTE
>Mature_289_residues
AAEFKHISVLKEELVAGLGVKPEGHYLDVTLGGGGHTELILQQYPDVRVTGVDRDSQAIAAASERLKSFGDRFRAVRSNF
GEYQPQGEKFDGIIADLGVSSVQFDQGDRGFSFRFDAPLDMRMDQQQTLTAADIVNTYEEKALANLFYEYGDERLSRQIA
KKIVMKRPIQTTKELEEIVFYTYHPKARKVKIHPATRVFQALRIAVNGELDALQYLLVNAPQWLKPQGRLGIISFHSLED
RLVKNAFRQRDIWRILTKKPMVASETEINQNPRARSAKLRFAELKETTE

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=333, Percent_Identity=36.6366366366366, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI165377202, Length=201, Percent_Identity=38.8059701492537, Blast_Score=129, Evalue=3e-30,
Organism=Escherichia coli, GI1786270, Length=317, Percent_Identity=42.9022082018927, Blast_Score=208, Evalue=3e-55,
Organism=Drosophila melanogaster, GI62472493, Length=326, Percent_Identity=35.8895705521472, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI28571637, Length=326, Percent_Identity=35.8895705521472, Blast_Score=172, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH_SYNP2 (B1XP73)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001734922.1
- ProteinModelPortal:   B1XP73
- GeneID:   6056841
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A1677
- HOGENOM:   HBG302779
- OMA:   PQLDDPE
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 33000; Mature: 32869

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: BINDING 54-54 BINDING 81-81 BINDING 97-97 BINDING 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAEFKHISVLKEELVAGLGVKPEGHYLDVTLGGGGHTELILQQYPDVRVTGVDRDSQAI
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHCCCEEEEECCCCHHHH
AAASERLKSFGDRFRAVRSNFGEYQPQGEKFDGIIADLGVSSVQFDQGDRGFSFRFDAPL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCEEEECCCCCCEEEEECCCC
DMRMDQQQTLTAADIVNTYEEKALANLFYEYGDERLSRQIAKKIVMKRPIQTTKELEEIV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHE
FYTYHPKARKVKIHPATRVFQALRIAVNGELDALQYLLVNAPQWLKPQGRLGIISFHSLE
EEEECCCCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHCCCCCCEEEEEHHHHH
DRLVKNAFRQRDIWRILTKKPMVASETEINQNPRARSAKLRFAELKETTE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AAEFKHISVLKEELVAGLGVKPEGHYLDVTLGGGGHTELILQQYPDVRVTGVDRDSQAI
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHCCCEEEEECCCCHHHH
AAASERLKSFGDRFRAVRSNFGEYQPQGEKFDGIIADLGVSSVQFDQGDRGFSFRFDAPL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCEEEECCCCCCEEEEECCCC
DMRMDQQQTLTAADIVNTYEEKALANLFYEYGDERLSRQIAKKIVMKRPIQTTKELEEIV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHE
FYTYHPKARKVKIHPATRVFQALRIAVNGELDALQYLLVNAPQWLKPQGRLGIISFHSLE
EEEECCCCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHCCCCCCEEEEEHHHHH
DRLVKNAFRQRDIWRILTKKPMVASETEINQNPRARSAKLRFAELKETTE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA