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The map label for this gene is envM [H]

Identifier: 170078283

GI number: 170078283

Start: 1759379

End: 1760155

Strand: Direct

Name: envM [H]

Synonym: SYNPCC7002_A1676

Alternate gene names: 170078283

Gene position: 1759379-1760155 (Clockwise)

Preceding gene: 170078279

Following gene: 170078284

Centisome position: 58.49

GC content: 51.22

Gene sequence:

>777_bases
ATGCTTGATTTAACCGGAAAAAATGCCCTAGTCACTGGGATTGCAAATAATAAGTCCATTGCCTGGGGGATCGCCCAACA
ATTACATGCCGCCGGGGCAAATATTGGGGTTACCTATCTCCCCGATGATAAGGGACGGTTCGAGAAAAAAGTAGGTGAGC
TTGTGGCGCCCCTCAACCCTTCCCTTTTTCTCCCCTGTAATGTGCAGGATGATGCCCAGGTGGATCAAGTGTTTGAGTCT
GTCAAAAAAGAGTGGGGCAAGTTAGATATTTTGATCCATTGCCTTGCCTTTGCGAACCGCGAAGATTTGACGGGTGATTT
TAGTGATACTTCACGGGATGGGTTTAATACGGCCCTTGACATTAGTGCCTATTCTTTAACGCGTCTGGCCCGGGGGGCTA
AAACCGTGATGACCGAAGGGGGCGCCATTGTGACCCTGACTTATTTGGGTGGGGTGAAAGTCATCCCTAATTACAATGTG
ATGGGTGTGGCAAAGTCGGCCCTTGAAATGAGTGTGCGTTACCTCGCGGCGGATCTGGGCCCCAGTAATATTCGCGTGAA
TGCCATTTCGGCTGGCCCGATCCGGACTTTGGCGTCTTCAGCGGTGGGCGGCATCCTCGATATGATTCACCATGTGGAAG
CCACGGCTCCTTTGCGTCGGACTGTGACCCAAAAGGAAGTGGGTAATGCGGCGGCTTTCTTGTGTAGCGATCTTTCTAGC
GGGGTCACGGGTCAAGTGCTCTATGTGGATTCTGGCTACGAAATTATGGGGATGTAA

Upstream 100 bases:

>100_bases
ATTTGCCCTAAAGTAGCCGTTTGCATCGAAGTCACCAGAGCGCGAAGATAATATACGCTGGCTTCTTGGCTTTAATTTTT
TATACTTTTTGAGAACCCAT

Downstream 100 bases:

>100_bases
TGTCCTGGTTTAGTGGCGATCGCCCTTGGGTTCCCCCTCAGTGATAGGGGGATTTTGTTTTTTATTGGATAGGTTCATGG
CGGCAGAGTTTAAACATATT

Product: enoyl-(acyl carrier protein) reductase

Products: NA

Alternate protein names: NADH-dependent enoyl-ACP reductase [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MLDLTGKNALVTGIANNKSIAWGIAQQLHAAGANIGVTYLPDDKGRFEKKVGELVAPLNPSLFLPCNVQDDAQVDQVFES
VKKEWGKLDILIHCLAFANREDLTGDFSDTSRDGFNTALDISAYSLTRLARGAKTVMTEGGAIVTLTYLGGVKVIPNYNV
MGVAKSALEMSVRYLAADLGPSNIRVNAISAGPIRTLASSAVGGILDMIHHVEATAPLRRTVTQKEVGNAAAFLCSDLSS
GVTGQVLYVDSGYEIMGM

Sequences:

>Translated_258_residues
MLDLTGKNALVTGIANNKSIAWGIAQQLHAAGANIGVTYLPDDKGRFEKKVGELVAPLNPSLFLPCNVQDDAQVDQVFES
VKKEWGKLDILIHCLAFANREDLTGDFSDTSRDGFNTALDISAYSLTRLARGAKTVMTEGGAIVTLTYLGGVKVIPNYNV
MGVAKSALEMSVRYLAADLGPSNIRVNAISAGPIRTLASSAVGGILDMIHHVEATAPLRRTVTQKEVGNAAAFLCSDLSS
GVTGQVLYVDSGYEIMGM
>Mature_258_residues
MLDLTGKNALVTGIANNKSIAWGIAQQLHAAGANIGVTYLPDDKGRFEKKVGELVAPLNPSLFLPCNVQDDAQVDQVFES
VKKEWGKLDILIHCLAFANREDLTGDFSDTSRDGFNTALDISAYSLTRLARGAKTVMTEGGAIVTLTYLGGVKVIPNYNV
MGVAKSALEMSVRYLAADLGPSNIRVNAISAGPIRTLASSAVGGILDMIHHVEATAPLRRTVTQKEVGNAAAFLCSDLSS
GVTGQVLYVDSGYEIMGM

Specific function: Fatty acid biosynthesis pathway; second reduction step. [C]

COG id: COG0623

COG function: function code I; Enoyl-[acyl-carrier-protein] reductase (NADH)

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily [H]

Homologues:

Organism=Homo sapiens, GI10190704, Length=208, Percent_Identity=32.6923076923077, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=25.8823529411765, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7705925, Length=256, Percent_Identity=27.34375, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787545, Length=257, Percent_Identity=48.6381322957198, Blast_Score=256, Evalue=1e-69,
Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=29.1187739463602, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=28.515625, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=25.3061224489796, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367365, Length=253, Percent_Identity=27.6679841897233, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=27.6679841897233, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=26.171875, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87082160, Length=259, Percent_Identity=25.0965250965251, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=272, Percent_Identity=27.5735294117647, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=200, Percent_Identity=27, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=185, Percent_Identity=27.027027027027, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644337, Length=183, Percent_Identity=30.6010928961749, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357041, Length=205, Percent_Identity=27.3170731707317, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28571526, Length=225, Percent_Identity=30.2222222222222, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=26.3565891472868, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR014358
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.9 [H]

Molecular weight: Translated: 27348; Mature: 27348

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLTGKNALVTGIANNKSIAWGIAQQLHAAGANIGVTYLPDDKGRFEKKVGELVAPLNP
CCCCCCCCEEEEEECCCCEEHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCC
SLFLPCNVQDDAQVDQVFESVKKEWGKLDILIHCLAFANREDLTGDFSDTSRDGFNTALD
CEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
ISAYSLTRLARGAKTVMTEGGAIVTLTYLGGVKVIPNYNVMGVAKSALEMSVRYLAADLG
HHHHHHHHHHCCHHHEEECCCCEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHCCC
PSNIRVNAISAGPIRTLASSAVGGILDMIHHVEATAPLRRTVTQKEVGNAAAFLCSDLSS
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
GVTGQVLYVDSGYEIMGM
CCCEEEEEEECCEEEECC
>Mature Secondary Structure
MLDLTGKNALVTGIANNKSIAWGIAQQLHAAGANIGVTYLPDDKGRFEKKVGELVAPLNP
CCCCCCCCEEEEEECCCCEEHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCC
SLFLPCNVQDDAQVDQVFESVKKEWGKLDILIHCLAFANREDLTGDFSDTSRDGFNTALD
CEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
ISAYSLTRLARGAKTVMTEGGAIVTLTYLGGVKVIPNYNVMGVAKSALEMSVRYLAADLG
HHHHHHHHHHCCHHHEEECCCCEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHCCC
PSNIRVNAISAGPIRTLASSAVGGILDMIHHVEATAPLRRTVTQKEVGNAAAFLCSDLSS
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
GVTGQVLYVDSGYEIMGM
CCCEEEEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8391534; 11759840 [H]