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The map label for this gene is clpP [H]

Identifier: 170078144

GI number: 170078144

Start: 1619573

End: 1620166

Strand: Reverse

Name: clpP [H]

Synonym: SYNPCC7002_A1535

Alternate gene names: 170078144

Gene position: 1620166-1619573 (Counterclockwise)

Preceding gene: 170078145

Following gene: 170078143

Centisome position: 53.86

GC content: 52.53

Gene sequence:

>594_bases
ATGGGTGGGACGGTGGTGCCGATGGTTGTCGAACAATCTGGCATGGGAGAACGGGCCTTCGATATTTACTCCCGTCTCCT
GCGGGAACGGATTGTGTTCCTCGGTACCGCCATTGATGACACCGTTGCTGACTCTGTGGTGGCCCAGTTGCTCTTTTTAG
ACGCCGAAGATGCCGATAAAGACATCCAACTCTACATCAACTCCCCCGGTGGTTCCGTTTATGCAGGGATGGCGATTTAC
GACACCATGCAACAGATTCGTCCCAATGTGGTGACCATTTGCTACGGCATCGCTGCCAGTATGGGCGCTTTTCTCCTCTC
AGGAGGCACCAAGGGTAAGCGGATGGCCCTGCCCAGTTCTCGGATTATGATTCACCAACCCCTCGGTGGTGCCCAAGGCC
AAGCGGTGGATATCGAAATTCAAGCCAAGGAAATCCTCTACATCAAAGATAAATTAAATACGTTGATCGCTGATCATACG
GGTCAACCCTTTGATAAGGTGGCAGAAGATACCGAGCGGGACTTCTATATGTCCGCTGAAGAGGCTTGCCAGTATGGTTT
GATCGACCAAGTGATCGCCCCGAACGCCGCTTAA

Upstream 100 bases:

>100_bases
TCCTGTTCATCCCCCAAAACATTAGCATCGAGCTTCCATGGTTCAATCAACTACCTCCTATCAACACCTTTCTAGCCAAG
CCGTCCCCTACAGCTACTCC

Downstream 100 bases:

>100_bases
CCCCATCGCTCACGTTATCCAGAGGCCCTACTCCAAAACCCATGTCTAAATACGACTCCCATCTCAAATGTTCCTTTTGT
GGTAAGTCCCAAGAACAGGT

Product: Clp protease

Products: NA

Alternate protein names: Endopeptidase Clp 2 [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MGGTVVPMVVEQSGMGERAFDIYSRLLRERIVFLGTAIDDTVADSVVAQLLFLDAEDADKDIQLYINSPGGSVYAGMAIY
DTMQQIRPNVVTICYGIAASMGAFLLSGGTKGKRMALPSSRIMIHQPLGGAQGQAVDIEIQAKEILYIKDKLNTLIADHT
GQPFDKVAEDTERDFYMSAEEACQYGLIDQVIAPNAA

Sequences:

>Translated_197_residues
MGGTVVPMVVEQSGMGERAFDIYSRLLRERIVFLGTAIDDTVADSVVAQLLFLDAEDADKDIQLYINSPGGSVYAGMAIY
DTMQQIRPNVVTICYGIAASMGAFLLSGGTKGKRMALPSSRIMIHQPLGGAQGQAVDIEIQAKEILYIKDKLNTLIADHT
GQPFDKVAEDTERDFYMSAEEACQYGLIDQVIAPNAA
>Mature_196_residues
GGTVVPMVVEQSGMGERAFDIYSRLLRERIVFLGTAIDDTVADSVVAQLLFLDAEDADKDIQLYINSPGGSVYAGMAIYD
TMQQIRPNVVTICYGIAASMGAFLLSGGTKGKRMALPSSRIMIHQPLGGAQGQAVDIEIQAKEILYIKDKLNTLIADHTG
QPFDKVAEDTERDFYMSAEEACQYGLIDQVIAPNAA

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=188, Percent_Identity=57.9787234042553, Blast_Score=221, Evalue=3e-58,
Organism=Escherichia coli, GI1786641, Length=189, Percent_Identity=61.9047619047619, Blast_Score=258, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI17538017, Length=192, Percent_Identity=53.125, Blast_Score=214, Evalue=2e-56,
Organism=Drosophila melanogaster, GI20129427, Length=189, Percent_Identity=53.968253968254, Blast_Score=217, Evalue=5e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 21315; Mature: 21183

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGTVVPMVVEQSGMGERAFDIYSRLLRERIVFLGTAIDDTVADSVVAQLLFLDAEDADK
CCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
DIQLYINSPGGSVYAGMAIYDTMQQIRPNVVTICYGIAASMGAFLLSGGTKGKRMALPSS
EEEEEEECCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC
RIMIHQPLGGAQGQAVDIEIQAKEILYIKDKLNTLIADHTGQPFDKVAEDTERDFYMSAE
CEEEECCCCCCCCCEEEEEEECCEEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHEEECHH
EACQYGLIDQVIAPNAA
HHHHHCCHHHHHCCCCC
>Mature Secondary Structure 
GGTVVPMVVEQSGMGERAFDIYSRLLRERIVFLGTAIDDTVADSVVAQLLFLDAEDADK
CCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
DIQLYINSPGGSVYAGMAIYDTMQQIRPNVVTICYGIAASMGAFLLSGGTKGKRMALPSS
EEEEEEECCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC
RIMIHQPLGGAQGQAVDIEIQAKEILYIKDKLNTLIADHTGQPFDKVAEDTERDFYMSAE
CEEEECCCCCCCCCEEEEEEECCEEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHEEECHH
EACQYGLIDQVIAPNAA
HHHHHCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]