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The map label for this gene is zwf [H]

Identifier: 170078068

GI number: 170078068

Start: 1532427

End: 1533956

Strand: Reverse

Name: zwf [H]

Synonym: SYNPCC7002_A1459

Alternate gene names: 170078068

Gene position: 1533956-1532427 (Counterclockwise)

Preceding gene: 170078069

Following gene: 170078067

Centisome position: 51.0

GC content: 51.24

Gene sequence:

>1530_bases
ATGGTTGCCTTACAAGAAAATCCCCTCAGAGTCGGACTCCGCCAAGAACGCACCCCAGACCCCCTCATCATCGTTATTTT
TGGCGCATCCGGCGATCTCACCCAGCGTAAACTCGTTCCCTCCCTCTACGCCCTCAAAAAAGATAATTTATTGCCACCGG
AGATCACCATTGTCGGTGTCGCTCGGCGGGACTGGAGCCACGATTACTTCCGCGAACAAATGCGCCAGGGCATTGAGGAA
TTTTCTGACGGCATCGGCAGCGAAGACCTCTGGAACAACTTTGCCGAAGGGCTTTTTTATTGTTCCGGCAATATGGACGA
CCCCGACAGTTACCAGAAACTTAAAACCTTTTTAGACGAACTCGATCAAAAACGAGGTACCAGAGGTAATCGCGTCTTTT
ACCTTGCGGTCTCTCCGAAGTTTTTCCCGCCTGGCATCAAAAATCTGGGGGCGGCTGGGATGCTCAATGATCCTCTCAAA
CACCGCCTCGTCATTGAGAAACCTTTTGGCAAAGATCTCAGTTCTGCCCAAGTTTTAAACAATGTCGTTAAAAACGTCTG
CCGTGAGGAACAGGTTTATCGCATCGACCACTACCTTGGTAAAGAAACCGTCCAAAACCTATTGGTCTTTCGCTTTGCCA
ACGCCATCTTTGAACCCCTCTGGAATCGCCATTACGTCGATCACGTGCAAATTACCGTCGCCGAAACCGTCGGTGTCGAA
GATCGTGCTGGTTACTATGAAACCTCCGGCGCCCTGCGGGATATGTTGCAAAATCACCTGATGCAACTGTTTTGTTTAAC
GGCGATGGAAGCGCCCAATGCTTTAAATGCCGACAGTATTCGCAGCGAAAAAACCAAGGTATTACAGGCCACCCACCTCG
CCGATATCCATAATCTTGATAAATCAGCGATTCGAGGACAATACAAAGCCGGTTGGATGAAAGGCAAACCCGTCCCCGGT
TACCGGGAAGAATCCGGCGTCAATCCCGAATCAACGACGCCTACCTATGTGGCGATGAAATTTATGGTAGATAATTGGCG
CTGGCAAGGGGTGCCTTTCTATCTGCGCACCGGCAAGCGTTTGCCCAAGAAAGTTTCAGAAATTGCGATTCAATTTAAGC
AGGTGCCCCTGGCGATCTTCCCATCGGCAGCAAAACAGGCGAATCCCAATACCCTGGCCCTGCGAATTCAACCCAATGAG
GGCATTTCCCTACGCTTTGAGGCCAAGATGCCAGGCGCAGATATTAGAACCCGCAGCGTGGATATGGACTTTAGCTATGG
AACATCCTTTGCTATGGCTACCCAGGATGCTTACACCCGACTGCTTTTGGATTGTATGGTCGGTGATCAAACTCTCTTTA
CCCGGGCCGATGAGGTGGAGGAGGCTTGGCGTGTGGTGACACCAGCTCTAGCGGCGTGGGATGGGCCAGCGGATCCTAGC
AATGTGCCCCAATATGAGGCGGGGACTTGGGAACCGACAGAAGCGGAATTTTTGATTAATCGGGATGGTCGCCGTTGGCG
TCGGTTGTAG

Upstream 100 bases:

>100_bases
TAACCCATCTCACCAAAAAAAGCCCCCCTTCTGAAAGGGGGGTTACGGGGATATCAAAATCCCCTTCCAATTACCCCATT
GCTCCTTCAAATCCAGCCCT

Downstream 100 bases:

>100_bases
AGGCGAATTTCCAATTTTAGGGAACAAATATCGGCTCTCAGTGTTTGTTTATTTTTGATTTCTTAATTCTTTTCGCACGC
AAATTTCGCAAAAAACTCTC

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD [H]

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MVALQENPLRVGLRQERTPDPLIIVIFGASGDLTQRKLVPSLYALKKDNLLPPEITIVGVARRDWSHDYFREQMRQGIEE
FSDGIGSEDLWNNFAEGLFYCSGNMDDPDSYQKLKTFLDELDQKRGTRGNRVFYLAVSPKFFPPGIKNLGAAGMLNDPLK
HRLVIEKPFGKDLSSAQVLNNVVKNVCREEQVYRIDHYLGKETVQNLLVFRFANAIFEPLWNRHYVDHVQITVAETVGVE
DRAGYYETSGALRDMLQNHLMQLFCLTAMEAPNALNADSIRSEKTKVLQATHLADIHNLDKSAIRGQYKAGWMKGKPVPG
YREESGVNPESTTPTYVAMKFMVDNWRWQGVPFYLRTGKRLPKKVSEIAIQFKQVPLAIFPSAAKQANPNTLALRIQPNE
GISLRFEAKMPGADIRTRSVDMDFSYGTSFAMATQDAYTRLLLDCMVGDQTLFTRADEVEEAWRVVTPALAAWDGPADPS
NVPQYEAGTWEPTEAEFLINRDGRRWRRL

Sequences:

>Translated_509_residues
MVALQENPLRVGLRQERTPDPLIIVIFGASGDLTQRKLVPSLYALKKDNLLPPEITIVGVARRDWSHDYFREQMRQGIEE
FSDGIGSEDLWNNFAEGLFYCSGNMDDPDSYQKLKTFLDELDQKRGTRGNRVFYLAVSPKFFPPGIKNLGAAGMLNDPLK
HRLVIEKPFGKDLSSAQVLNNVVKNVCREEQVYRIDHYLGKETVQNLLVFRFANAIFEPLWNRHYVDHVQITVAETVGVE
DRAGYYETSGALRDMLQNHLMQLFCLTAMEAPNALNADSIRSEKTKVLQATHLADIHNLDKSAIRGQYKAGWMKGKPVPG
YREESGVNPESTTPTYVAMKFMVDNWRWQGVPFYLRTGKRLPKKVSEIAIQFKQVPLAIFPSAAKQANPNTLALRIQPNE
GISLRFEAKMPGADIRTRSVDMDFSYGTSFAMATQDAYTRLLLDCMVGDQTLFTRADEVEEAWRVVTPALAAWDGPADPS
NVPQYEAGTWEPTEAEFLINRDGRRWRRL
>Mature_509_residues
MVALQENPLRVGLRQERTPDPLIIVIFGASGDLTQRKLVPSLYALKKDNLLPPEITIVGVARRDWSHDYFREQMRQGIEE
FSDGIGSEDLWNNFAEGLFYCSGNMDDPDSYQKLKTFLDELDQKRGTRGNRVFYLAVSPKFFPPGIKNLGAAGMLNDPLK
HRLVIEKPFGKDLSSAQVLNNVVKNVCREEQVYRIDHYLGKETVQNLLVFRFANAIFEPLWNRHYVDHVQITVAETVGVE
DRAGYYETSGALRDMLQNHLMQLFCLTAMEAPNALNADSIRSEKTKVLQATHLADIHNLDKSAIRGQYKAGWMKGKPVPG
YREESGVNPESTTPTYVAMKFMVDNWRWQGVPFYLRTGKRLPKKVSEIAIQFKQVPLAIFPSAAKQANPNTLALRIQPNE
GISLRFEAKMPGADIRTRSVDMDFSYGTSFAMATQDAYTRLLLDCMVGDQTLFTRADEVEEAWRVVTPALAAWDGPADPS
NVPQYEAGTWEPTEAEFLINRDGRRWRRL

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI109389365, Length=490, Percent_Identity=39.5918367346939, Blast_Score=338, Evalue=6e-93,
Organism=Homo sapiens, GI108773793, Length=490, Percent_Identity=39.5918367346939, Blast_Score=338, Evalue=7e-93,
Organism=Homo sapiens, GI52145310, Length=487, Percent_Identity=29.5687885010267, Blast_Score=175, Evalue=7e-44,
Organism=Escherichia coli, GI1788158, Length=494, Percent_Identity=44.7368421052632, Blast_Score=424, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17538218, Length=492, Percent_Identity=38.2113821138211, Blast_Score=348, Evalue=3e-96,
Organism=Saccharomyces cerevisiae, GI6324088, Length=463, Percent_Identity=34.7732181425486, Blast_Score=286, Evalue=7e-78,
Organism=Drosophila melanogaster, GI24643350, Length=480, Percent_Identity=36.6666666666667, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24643352, Length=480, Percent_Identity=36.6666666666667, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI221513548, Length=483, Percent_Identity=31.6770186335404, Blast_Score=229, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 57759; Mature: 57759

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00069 G6P_DEHYDROGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVALQENPLRVGLRQERTPDPLIIVIFGASGDLTQRKLVPSLYALKKDNLLPPEITIVGV
CCCCCCCCCEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEE
ARRDWSHDYFREQMRQGIEEFSDGIGSEDLWNNFAEGLFYCSGNMDDPDSYQKLKTFLDE
ECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHH
LDQKRGTRGNRVFYLAVSPKFFPPGIKNLGAAGMLNDPLKHRLVIEKPFGKDLSSAQVLN
HHHHHCCCCCEEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHH
NVVKNVCREEQVYRIDHYLGKETVQNLLVFRFANAIFEPLWNRHYVDHVQITVAETVGVE
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCCC
DRAGYYETSGALRDMLQNHLMQLFCLTAMEAPNALNADSIRSEKTKVLQATHLADIHNLD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
KSAIRGQYKAGWMKGKPVPGYREESGVNPESTTPTYVAMKFMVDNWRWQGVPFYLRTGKR
HHHHCCCHHCCCCCCCCCCCCCHHCCCCCCCCCCHHEEEEEECCCCEECCCCEEECCCCH
LPKKVSEIAIQFKQVPLAIFPSAAKQANPNTLALRIQPNEGISLRFEAKMPGADIRTRSV
HHHHHHHHHHHHHHCCEEECCCHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCCEEEEE
DMDFSYGTSFAMATQDAYTRLLLDCMVGDQTLFTRADEVEEAWRVVTPALAAWDGPADPS
ECCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCC
NVPQYEAGTWEPTEAEFLINRDGRRWRRL
CCCCCCCCCCCCCCCEEEECCCCHHHHCC
>Mature Secondary Structure
MVALQENPLRVGLRQERTPDPLIIVIFGASGDLTQRKLVPSLYALKKDNLLPPEITIVGV
CCCCCCCCCEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEE
ARRDWSHDYFREQMRQGIEEFSDGIGSEDLWNNFAEGLFYCSGNMDDPDSYQKLKTFLDE
ECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHH
LDQKRGTRGNRVFYLAVSPKFFPPGIKNLGAAGMLNDPLKHRLVIEKPFGKDLSSAQVLN
HHHHHCCCCCEEEEEEECCCCCCCCHHHCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHH
NVVKNVCREEQVYRIDHYLGKETVQNLLVFRFANAIFEPLWNRHYVDHVQITVAETVGVE
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCCC
DRAGYYETSGALRDMLQNHLMQLFCLTAMEAPNALNADSIRSEKTKVLQATHLADIHNLD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
KSAIRGQYKAGWMKGKPVPGYREESGVNPESTTPTYVAMKFMVDNWRWQGVPFYLRTGKR
HHHHCCCHHCCCCCCCCCCCCCHHCCCCCCCCCCHHEEEEEECCCCEECCCCEEECCCCH
LPKKVSEIAIQFKQVPLAIFPSAAKQANPNTLALRIQPNEGISLRFEAKMPGADIRTRSV
HHHHHHHHHHHHHHCCEEECCCHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCCEEEEE
DMDFSYGTSFAMATQDAYTRLLLDCMVGDQTLFTRADEVEEAWRVVTPALAAWDGPADPS
ECCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCC
NVPQYEAGTWEPTEAEFLINRDGRRWRRL
CCCCCCCCCCCCCCCEEEECCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]