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The map label for this gene is tig

Identifier: 170077891

GI number: 170077891

Start: 1323163

End: 1324527

Strand: Direct

Name: tig

Synonym: SYNPCC7002_A1276

Alternate gene names: 170077891

Gene position: 1323163-1324527 (Clockwise)

Preceding gene: 170077887

Following gene: 170077893

Centisome position: 43.99

GC content: 51.14

Gene sequence:

>1365_bases
ATGAAAGTTATCCAGGAAAAGCTTCCTGCCAGCCAAGTTGGGCTAGAAATCGAAGTCCCCGCTGACGTCACCCAAAAAGC
CTATGATGACACAGTGCGGAAACTCGCCCGTACCGTGAACCTCCCCGGTTTCCGGAAAGGTAAAGTTCCCAAGCAGATTT
TGATCCAACGGTTAGGCCCCAATCGCATTAAGGCGTCTGTCCTTGAGGATTTGATCGACGACAGCTTAAAAGCGGCGATC
GCCCAAGAAAACATTGAGGCCCTAGGAAATTTCCAGCTCAAATCTTCCTTCGATGACCTGATCAGCGCCTACAAACCCGG
TGAAGCCTCCAGTTTCAAGGCCGCCGTGGATGTCCCCGCCACCGTCACCCTCAACAGCTACAAAGGCCTCAGCTTCAAGG
CCGAAAAGAGTGAATATGATCCGGCGGATCTCGATGAATTTCTCACCCAGAAACAACGCGAACTGGCTACCCTTGTCCCC
GTCGAAGACCGGGCTGCCCAAATGGGAGATGTGGCGATCGCCGATTACGAAGGTCGCTATGTAAACGACGCTGGCGAAGA
AGAAGAGGACATTATCCCCGGCACCCAAGCCGAAGACTTTTCCCTCGACCTCGAAGAAGGCAAATTTATCCCAGGCTTTG
TGGATGGTTTTGTCGGCATGAAACCCGAAGAAACCAAGAAATTCACCGTTACCTTCCCCGAAGACTACGGCAACGAAGAA
ATGGCCGGGAAACAAGTCTCCTTCACCGTCACCCTCAAGGAACTCAAGAGCCGCGAACTACCGGAACTCGATGATGAGTT
TGCCAGCGAAGCCACCAACGAAGAATTTGAAACCCTCGCGGCTTGGCAAGAAAGTCTAGAAGCCCAACTAAAAGAAAACG
CTGAAATCAGCACCAAAAACAGCGTGCGTCGTTATCTGCTAGAACAACTCGCTGCCAATAACAGCACCGAACTGCCAGAA
GTGAGCGTCAACGAAGAAATTACCGCAGTCCTCACCCAGCAGATGATGGAATTCAGCCGCATGGGCATCGATGTGAATCG
CATTTTTACCAAGGATATGATTCCTAAACTGCGAGAAACGGCTCGCCCAGAAGCAGAACAACGGCTCAGCAACTCCTTGA
TTCTCACGGAAATTGCTAAGGTCGAGAAGATCGAAATTGATACCGACAAATTCAACGAGCGCCTAGAGGAAGCTAAGGCA
GAACTCCAGGAAGGCTTTGATGAAGAGCGTCTCCAGGAAGCCATCAAAGAAGAGTTGACCATTGATGCAACCCTCGATTG
GCTCGAAGAGCAGTCTGAGATCGAATTTGTCCCTGCCGGAACTCTCGAAGCAGAAGAGGCTGAGGCAGCAAACGGAGAAG
AATAG

Upstream 100 bases:

>100_bases
TGGAGCGCTCAATTCAGACCCCTAAAGGGGCGATCGCCAACGAACAGAACTATCCTAAGACCCTTAGTTGTAACTTATAT
ATTAGAACCTTTAAACATCG

Downstream 100 bases:

>100_bases
AGCTTTAGACGCTTATGTTTAAACTCTAAAACTAATTGCGAAAAGACCCCACTTGGGGTCTTTTTTGTTGGTATCTCAGG
TTTTCAAGCTATCCCATCAC

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MKVIQEKLPASQVGLEIEVPADVTQKAYDDTVRKLARTVNLPGFRKGKVPKQILIQRLGPNRIKASVLEDLIDDSLKAAI
AQENIEALGNFQLKSSFDDLISAYKPGEASSFKAAVDVPATVTLNSYKGLSFKAEKSEYDPADLDEFLTQKQRELATLVP
VEDRAAQMGDVAIADYEGRYVNDAGEEEEDIIPGTQAEDFSLDLEEGKFIPGFVDGFVGMKPEETKKFTVTFPEDYGNEE
MAGKQVSFTVTLKELKSRELPELDDEFASEATNEEFETLAAWQESLEAQLKENAEISTKNSVRRYLLEQLAANNSTELPE
VSVNEEITAVLTQQMMEFSRMGIDVNRIFTKDMIPKLRETARPEAEQRLSNSLILTEIAKVEKIEIDTDKFNERLEEAKA
ELQEGFDEERLQEAIKEELTIDATLDWLEEQSEIEFVPAGTLEAEEAEAANGEE

Sequences:

>Translated_454_residues
MKVIQEKLPASQVGLEIEVPADVTQKAYDDTVRKLARTVNLPGFRKGKVPKQILIQRLGPNRIKASVLEDLIDDSLKAAI
AQENIEALGNFQLKSSFDDLISAYKPGEASSFKAAVDVPATVTLNSYKGLSFKAEKSEYDPADLDEFLTQKQRELATLVP
VEDRAAQMGDVAIADYEGRYVNDAGEEEEDIIPGTQAEDFSLDLEEGKFIPGFVDGFVGMKPEETKKFTVTFPEDYGNEE
MAGKQVSFTVTLKELKSRELPELDDEFASEATNEEFETLAAWQESLEAQLKENAEISTKNSVRRYLLEQLAANNSTELPE
VSVNEEITAVLTQQMMEFSRMGIDVNRIFTKDMIPKLRETARPEAEQRLSNSLILTEIAKVEKIEIDTDKFNERLEEAKA
ELQEGFDEERLQEAIKEELTIDATLDWLEEQSEIEFVPAGTLEAEEAEAANGEE
>Mature_454_residues
MKVIQEKLPASQVGLEIEVPADVTQKAYDDTVRKLARTVNLPGFRKGKVPKQILIQRLGPNRIKASVLEDLIDDSLKAAI
AQENIEALGNFQLKSSFDDLISAYKPGEASSFKAAVDVPATVTLNSYKGLSFKAEKSEYDPADLDEFLTQKQRELATLVP
VEDRAAQMGDVAIADYEGRYVNDAGEEEEDIIPGTQAEDFSLDLEEGKFIPGFVDGFVGMKPEETKKFTVTFPEDYGNEE
MAGKQVSFTVTLKELKSRELPELDDEFASEATNEEFETLAAWQESLEAQLKENAEISTKNSVRRYLLEQLAANNSTELPE
VSVNEEITAVLTQQMMEFSRMGIDVNRIFTKDMIPKLRETARPEAEQRLSNSLILTEIAKVEKIEIDTDKFNERLEEAKA
ELQEGFDEERLQEAIKEELTIDATLDWLEEQSEIEFVPAGTLEAEEAEAANGEE

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=385, Percent_Identity=29.0909090909091, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_SYNP2 (B1XL18)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001734529.1
- ProteinModelPortal:   B1XL18
- GeneID:   6057427
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A1276
- HOGENOM:   HBG635105
- OMA:   RFIPGFE
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 50829; Mature: 50829

Theoretical pI: Translated: 4.05; Mature: 4.05

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIQEKLPASQVGLEIEVPADVTQKAYDDTVRKLARTVNLPGFRKGKVPKQILIQRLGP
CCCHHHHCCHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCC
NRIKASVLEDLIDDSLKAAIAQENIEALGNFQLKSSFDDLISAYKPGEASSFKAAVDVPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCE
TVTLNSYKGLSFKAEKSEYDPADLDEFLTQKQRELATLVPVEDRAAQMGDVAIADYEGRY
EEEECCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCEEEECCCCCC
VNDAGEEEEDIIPGTQAEDFSLDLEEGKFIPGFVDGFVGMKPEETKKFTVTFPEDYGNEE
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHCCCCCCCCCEEEEECCHHCCCHH
MAGKQVSFTVTLKELKSRELPELDDEFASEATNEEFETLAAWQESLEAQLKENAEISTKN
HCCCEEEEEEEHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
SVRRYLLEQLAANNSTELPEVSVNEEITAVLTQQMMEFSRMGIDVNRIFTKDMIPKLRET
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ARPEAEQRLSNSLILTEIAKVEKIEIDTDKFNERLEEAKAELQEGFDEERLQEAIKEELT
CCCHHHHHHHCCHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
IDATLDWLEEQSEIEFVPAGTLEAEEAEAANGEE
HHHHHHHHHCCCCEEEECCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MKVIQEKLPASQVGLEIEVPADVTQKAYDDTVRKLARTVNLPGFRKGKVPKQILIQRLGP
CCCHHHHCCHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCC
NRIKASVLEDLIDDSLKAAIAQENIEALGNFQLKSSFDDLISAYKPGEASSFKAAVDVPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCE
TVTLNSYKGLSFKAEKSEYDPADLDEFLTQKQRELATLVPVEDRAAQMGDVAIADYEGRY
EEEECCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCEEEECCCCCC
VNDAGEEEEDIIPGTQAEDFSLDLEEGKFIPGFVDGFVGMKPEETKKFTVTFPEDYGNEE
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHCCCCCCCCCEEEEECCHHCCCHH
MAGKQVSFTVTLKELKSRELPELDDEFASEATNEEFETLAAWQESLEAQLKENAEISTKN
HCCCEEEEEEEHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
SVRRYLLEQLAANNSTELPEVSVNEEITAVLTQQMMEFSRMGIDVNRIFTKDMIPKLRET
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ARPEAEQRLSNSLILTEIAKVEKIEIDTDKFNERLEEAKAELQEGFDEERLQEAIKEELT
CCCHHHHHHHCCHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
IDATLDWLEEQSEIEFVPAGTLEAEEAEAANGEE
HHHHHHHHHCCCCEEEECCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA