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The map label for this gene is ilvC

Identifier: 170077893

GI number: 170077893

Start: 1325731

End: 1326726

Strand: Direct

Name: ilvC

Synonym: SYNPCC7002_A1278

Alternate gene names: 170077893

Gene position: 1325731-1326726 (Clockwise)

Preceding gene: 170077891

Following gene: 170077895

Centisome position: 44.07

GC content: 50.3

Gene sequence:

>996_bases
ATGGCTCGCATGTATTATGATGCGGACGCAAACTTAGATCTGTTAAACGGCAAAACCGTTGCCATCATCGGCTATGGTTC
CCAGGGCCATGCCCATGCCCTCAACCTCAAAGACAGTGGGATTAACGTCGTTATCGGCCTATATGCCGGAAGTAAGTCCA
CAGCCAAAGCCGAAGCAGAAGGTCTAAAGGTTTTACCTGTTGCGGAAGCAGCAAAAGTGGCGGACTGGATCATGATTTTG
TTACCCGACGATGTCCAAAAATCTGTCTACACCAAAGATATTCTCCCCAACCTCCAAGCGGGCAATGTACTTTCCTTTGC
TCACGGCTTCAATATCAACTTCGGCCAAATCGTTCCCCCCGCTGATGTAGACGTTGTAATGGTTGCCCCTAAAGGCCCTG
GTCACCTCGTGCGTCGTACCTATGAACAAGGTCAAGGGGTGCCCGCATTATTCGCAGTTTACCAAGACGCCACAGGTCAA
GCCCGTGATTTGGCGATGGCCTATGCGAAAGGCATCGGCGGTACTCGCGGTGGCATCCTTGAAACCACGTTCCGAGAAGA
AACGGAGACTGATCTATTCGGTGAACAGGCAGTTCTCTGTGGTGGTCTGAGTGCTCTGATTAAAGCTGGTTTTGAAACCC
TCGTCGAAGCGGGTTACCAGCCGGAGTTGGCTTACTTTGAGTGTCTCCATGAAGTGAAGCTCATTGTTGACCTCGTTGTG
GAAGGTGGTCTGGCGAAAATGCGGGATAGCATTTCTACCACCGCTGAGTATGGTGATTATGTCAGTGGGCCACGGGTGAT
CACTGCTGAAACCAAAGCCGCAATGAAGGAAATTCTGACCGAAATCCAAACGGGTGAGTTTGCACGAAATTTCATCCTCG
AAAATCAGTCGGGTCAAGCGCAATTTACGGCTATTCGTCGCCGTGAAGCAGAACATCCCATTGAAGTTGTGGGTAAGGAT
CTGCGGGCAATGTTTAGCTGGTTGAAGGAAAGCTAA

Upstream 100 bases:

>100_bases
CAGCAAAAGTTCAGTTGACAACAATCTCCTATAATACGAAGTCTGCAGTATGCATTAACACATATTCTTAACTTTGTAAT
TTCCGTCGGAGAATTGTCCT

Downstream 100 bases:

>100_bases
TCGAGAAATTAGATTGATTTAATATTTAATAACAATATTAAGTTAAACCGATTAGGTGAGAGTCAGTGATTCTCACCTTT
TTTTTAACTGGGCGGTTTCA

Product: ketol-acid reductoisomerase

Products: NA

Alternate protein names: Acetohydroxy-acid isomeroreductase; Alpha-keto-beta-hydroxylacil reductoisomerase

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MARMYYDADANLDLLNGKTVAIIGYGSQGHAHALNLKDSGINVVIGLYAGSKSTAKAEAEGLKVLPVAEAAKVADWIMIL
LPDDVQKSVYTKDILPNLQAGNVLSFAHGFNINFGQIVPPADVDVVMVAPKGPGHLVRRTYEQGQGVPALFAVYQDATGQ
ARDLAMAYAKGIGGTRGGILETTFREETETDLFGEQAVLCGGLSALIKAGFETLVEAGYQPELAYFECLHEVKLIVDLVV
EGGLAKMRDSISTTAEYGDYVSGPRVITAETKAAMKEILTEIQTGEFARNFILENQSGQAQFTAIRRREAEHPIEVVGKD
LRAMFSWLKES

Sequences:

>Translated_331_residues
MARMYYDADANLDLLNGKTVAIIGYGSQGHAHALNLKDSGINVVIGLYAGSKSTAKAEAEGLKVLPVAEAAKVADWIMIL
LPDDVQKSVYTKDILPNLQAGNVLSFAHGFNINFGQIVPPADVDVVMVAPKGPGHLVRRTYEQGQGVPALFAVYQDATGQ
ARDLAMAYAKGIGGTRGGILETTFREETETDLFGEQAVLCGGLSALIKAGFETLVEAGYQPELAYFECLHEVKLIVDLVV
EGGLAKMRDSISTTAEYGDYVSGPRVITAETKAAMKEILTEIQTGEFARNFILENQSGQAQFTAIRRREAEHPIEVVGKD
LRAMFSWLKES
>Mature_330_residues
ARMYYDADANLDLLNGKTVAIIGYGSQGHAHALNLKDSGINVVIGLYAGSKSTAKAEAEGLKVLPVAEAAKVADWIMILL
PDDVQKSVYTKDILPNLQAGNVLSFAHGFNINFGQIVPPADVDVVMVAPKGPGHLVRRTYEQGQGVPALFAVYQDATGQA
RDLAMAYAKGIGGTRGGILETTFREETETDLFGEQAVLCGGLSALIKAGFETLVEAGYQPELAYFECLHEVKLIVDLVVE
GGLAKMRDSISTTAEYGDYVSGPRVITAETKAAMKEILTEIQTGEFARNFILENQSGQAQFTAIRRREAEHPIEVVGKDL
RAMFSWLKES

Specific function: Valine and isoleucine biosynthesis; second step. [C]

COG id: COG0059

COG function: function code EH; Ketol-acid reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketol-acid reductoisomerase family

Homologues:

Organism=Escherichia coli, GI1790210, Length=292, Percent_Identity=35.958904109589, Blast_Score=142, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6323387, Length=327, Percent_Identity=33.6391437308869, Blast_Score=151, Evalue=1e-37,

Paralogues:

None

Copy number: 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): ILVC_SYNP2 (B1XL20)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001734531.1
- ProteinModelPortal:   B1XL20
- SMR:   B1XL20
- GeneID:   6057424
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A1278
- HOGENOM:   HBG286525
- OMA:   MAYAKGI
- HAMAP:   MF_00435
- InterPro:   IPR008927
- InterPro:   IPR013023
- InterPro:   IPR000506
- InterPro:   IPR013328
- InterPro:   IPR013116
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR21371
- TIGRFAMs:   TIGR00465

Pfam domain/function: PF01450 IlvC; PF07991 IlvN; SSF48179 6DGDH_C_like

EC number: =1.1.1.86

Molecular weight: Translated: 35716; Mature: 35585

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: ACT_SITE 108-108

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARMYYDADANLDLLNGKTVAIIGYGSQGHAHALNLKDSGINVVIGLYAGSKSTAKAEAE
CCEEEECCCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCEEEEEEEECCCCCCHHHHC
GLKVLPVAEAAKVADWIMILLPDDVQKSVYTKDILPNLQAGNVLSFAHGFNINFGQIVPP
CEEEEEHHHHHHHHCEEEEEECCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCC
ADVDVVMVAPKGPGHLVRRTYEQGQGVPALFAVYQDATGQARDLAMAYAKGIGGTRGGIL
CCCCEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEE
ETTFREETETDLFGEQAVLCGGLSALIKAGFETLVEAGYQPELAYFECLHEVKLIVDLVV
EEHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
EGGLAKMRDSISTTAEYGDYVSGPRVITAETKAAMKEILTEIQTGEFARNFILENQSGQA
CCCHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHEECCCCCH
QFTAIRRREAEHPIEVVGKDLRAMFSWLKES
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARMYYDADANLDLLNGKTVAIIGYGSQGHAHALNLKDSGINVVIGLYAGSKSTAKAEAE
CEEEECCCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCEEEEEEEECCCCCCHHHHC
GLKVLPVAEAAKVADWIMILLPDDVQKSVYTKDILPNLQAGNVLSFAHGFNINFGQIVPP
CEEEEEHHHHHHHHCEEEEEECCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCC
ADVDVVMVAPKGPGHLVRRTYEQGQGVPALFAVYQDATGQARDLAMAYAKGIGGTRGGIL
CCCCEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEE
ETTFREETETDLFGEQAVLCGGLSALIKAGFETLVEAGYQPELAYFECLHEVKLIVDLVV
EEHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
EGGLAKMRDSISTTAEYGDYVSGPRVITAETKAAMKEILTEIQTGEFARNFILENQSGQA
CCCHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHEECCCCCH
QFTAIRRREAEHPIEVVGKDLRAMFSWLKES
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA