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The map label for this gene is lysC [H]

Identifier: 170077882

GI number: 170077882

Start: 1311921

End: 1313735

Strand: Reverse

Name: lysC [H]

Synonym: SYNPCC7002_A1267

Alternate gene names: 170077882

Gene position: 1313735-1311921 (Counterclockwise)

Preceding gene: 170077885

Following gene: 170077879

Centisome position: 43.67

GC content: 54.71

Gene sequence:

>1815_bases
ATGGCAATGATCGTTCAAAAATATGGCGGTACCTCCGTCGGCTCGGTAGAAAGAATTCAAGCGGTGGCCAAACGGGTACA
GCAACGGGCCCAAGCGGGCAATCAAATTGTCGTGGTGGTCTCTGCCATGGGAAAAACCACCGATGGTTTGGTGAAATTGG
CCCACGAAATCAGCACCAATCCCAACCGACGGGAAATGGATATGCTCCTCTCTACGGGGGAACAGGTCTCGATTTCTCTG
CTCAGTATGGCCCTCCAGGAACTGGGACAACCGGCAATTTCTCTCACTGGTGCCCAGGTGGGAATTGTTACTGAAGCGGA
ACATAGCCGCGCCCGCATCCTCGAAATTAAAACCGACCGCCTCCAACGGCACCTGCAAAAGGGAGAGGTGATCGTCGTGG
CGGGTTTCCAGGGCATTTCCAAAACCGAAGATCTAGAAATTACTACCCTGGGTCGGGGCGGATCGGATACTTCTGCGGTG
GCGATCGCCGCTGCTCTCAAGGCCTCCTGTTGTGAAATTTATACCGATGTGCCGGGGATTTTAACCACTGACCCGCGTAT
TGTCCCCGAAGCGCAACTGATGGCCGAAGTCACGTCCGATGAAATGCTAGAGCTTGCCAGTTTAGGGGCGAAGGTGCTTC
ATCCCCGCGCTGTCGAAATTGCGAAAAATTATGGGGTGCCTTTGGTGGTACGTTCCAGTTGGACTGAGGATCCGGGGACT
TGGGTGACCTCTGCCCCGGTGAGCGATCGCCCCTTGATTAACCTCGAAATTGCCAAAGCCGTCGATGCGGTGGAGTTTGA
TACTAACCAGGCCCGCATTGCGATGCTGCACATCCCTGATCGCCCCGGCGTCGCTGCCAAATTATTTGGAGAAATCGCCA
CCCACAATGTCGATGTGGATTTAATTATCCAGTCGATCCACGATGGCAACAGTAATGACATTGCCTTTACCGTGACCGAA
AATGCCGCCACCCAGGCCCAGGCGATCGCCGAAGCCATTGCCCCCACCCTCTGCGCTGGCACAGACCAAGATTTAAGCGA
CGTTGCGGTGATGAGCGCCAATGACATTGCCAAAATCACCATCTCTGGGGCTGGGATGATCGGCCGTCCCGGGATTGCCG
CCACCATGTTCCAAAGCCTGGCCGATGCAGGGATTAATATCGAGATGATTTCCACTTCGGAAGTGAAGGTGAGCTGCGTC
ATCCAGCAGACGGATTGTGACCGGGCGATCGCCACCCTCTGCGATGTTTTTGACATTGCCTCTTCCCCGATGAATGCGAC
CCCAGCGGCTCTCAATCCCGAAGATCACCCCCCCGTCCGGGGTGTCGCCCTTGACCTCAAACAAGCGCAACTGGCCATTC
GTCACGTGCCGGATAGTCCTGGTATGGCTGCCCAAATTTTTTCGCTGTTGGCCCACCAAAACATCAGCGTCGATATGATT
ATCCAGTCCCAACGGTGTCGTGTGCTCAACGGGGTAAAGACCCGTGACATTGCCTTTACCGTTGCCCAAGGGGATGCTGA
AGCGGCTCGCCTCGCCCTCTCTAGCATGGCAGAACAGCTAAATTTTGGGGAAATCGAAGTAGATCCGGCGATCGCCAAAG
TCAGTATTGTCGGTTCTGGGATGATTGGTGCACCGGGGGTTGCAGCTCGCTTCTTCCAAGCCCTTGCCACGGCAAAAATC
AATATTCAGATGATTACCACTTCTGAAATTAAAATTAGCTGCGTTGTCCCGGAAACCCAAGGCCAAGCCGCTCTGAAACT
CGTCCATGAAGCCTTTGCCCTCGGTGGTGAAGCAAAGGTGGAAGTCCCCGCCTAA

Upstream 100 bases:

>100_bases
CAGAAAAGTCGGTAGGATTTGCTAGAGTGGATCACCGATTTTCCAAAACATCTATGGAAAGCGAATTGTGTTTTAAGTTC
GGGAGAGTGAGGCAGGTTCC

Downstream 100 bases:

>100_bases
TCATTGCCCAAACCCAAGATTAGCCCGCCGAGGAGAATTAGGAGCAAAAGCCCCAGGATCATAAGTACGCCCATACAAAT
TCCCTAAAAATACAATCTGC

Product: aspartate kinase

Products: NA

Alternate protein names: Aspartate kinase 2; Aspartokinase II [H]

Number of amino acids: Translated: 604; Mature: 603

Protein sequence:

>604_residues
MAMIVQKYGGTSVGSVERIQAVAKRVQQRAQAGNQIVVVVSAMGKTTDGLVKLAHEISTNPNRREMDMLLSTGEQVSISL
LSMALQELGQPAISLTGAQVGIVTEAEHSRARILEIKTDRLQRHLQKGEVIVVAGFQGISKTEDLEITTLGRGGSDTSAV
AIAAALKASCCEIYTDVPGILTTDPRIVPEAQLMAEVTSDEMLELASLGAKVLHPRAVEIAKNYGVPLVVRSSWTEDPGT
WVTSAPVSDRPLINLEIAKAVDAVEFDTNQARIAMLHIPDRPGVAAKLFGEIATHNVDVDLIIQSIHDGNSNDIAFTVTE
NAATQAQAIAEAIAPTLCAGTDQDLSDVAVMSANDIAKITISGAGMIGRPGIAATMFQSLADAGINIEMISTSEVKVSCV
IQQTDCDRAIATLCDVFDIASSPMNATPAALNPEDHPPVRGVALDLKQAQLAIRHVPDSPGMAAQIFSLLAHQNISVDMI
IQSQRCRVLNGVKTRDIAFTVAQGDAEAARLALSSMAEQLNFGEIEVDPAIAKVSIVGSGMIGAPGVAARFFQALATAKI
NIQMITTSEIKISCVVPETQGQAALKLVHEAFALGGEAKVEVPA

Sequences:

>Translated_604_residues
MAMIVQKYGGTSVGSVERIQAVAKRVQQRAQAGNQIVVVVSAMGKTTDGLVKLAHEISTNPNRREMDMLLSTGEQVSISL
LSMALQELGQPAISLTGAQVGIVTEAEHSRARILEIKTDRLQRHLQKGEVIVVAGFQGISKTEDLEITTLGRGGSDTSAV
AIAAALKASCCEIYTDVPGILTTDPRIVPEAQLMAEVTSDEMLELASLGAKVLHPRAVEIAKNYGVPLVVRSSWTEDPGT
WVTSAPVSDRPLINLEIAKAVDAVEFDTNQARIAMLHIPDRPGVAAKLFGEIATHNVDVDLIIQSIHDGNSNDIAFTVTE
NAATQAQAIAEAIAPTLCAGTDQDLSDVAVMSANDIAKITISGAGMIGRPGIAATMFQSLADAGINIEMISTSEVKVSCV
IQQTDCDRAIATLCDVFDIASSPMNATPAALNPEDHPPVRGVALDLKQAQLAIRHVPDSPGMAAQIFSLLAHQNISVDMI
IQSQRCRVLNGVKTRDIAFTVAQGDAEAARLALSSMAEQLNFGEIEVDPAIAKVSIVGSGMIGAPGVAARFFQALATAKI
NIQMITTSEIKISCVVPETQGQAALKLVHEAFALGGEAKVEVPA
>Mature_603_residues
AMIVQKYGGTSVGSVERIQAVAKRVQQRAQAGNQIVVVVSAMGKTTDGLVKLAHEISTNPNRREMDMLLSTGEQVSISLL
SMALQELGQPAISLTGAQVGIVTEAEHSRARILEIKTDRLQRHLQKGEVIVVAGFQGISKTEDLEITTLGRGGSDTSAVA
IAAALKASCCEIYTDVPGILTTDPRIVPEAQLMAEVTSDEMLELASLGAKVLHPRAVEIAKNYGVPLVVRSSWTEDPGTW
VTSAPVSDRPLINLEIAKAVDAVEFDTNQARIAMLHIPDRPGVAAKLFGEIATHNVDVDLIIQSIHDGNSNDIAFTVTEN
AATQAQAIAEAIAPTLCAGTDQDLSDVAVMSANDIAKITISGAGMIGRPGIAATMFQSLADAGINIEMISTSEVKVSCVI
QQTDCDRAIATLCDVFDIASSPMNATPAALNPEDHPPVRGVALDLKQAQLAIRHVPDSPGMAAQIFSLLAHQNISVDMII
QSQRCRVLNGVKTRDIAFTVAQGDAEAARLALSSMAEQLNFGEIEVDPAIAKVSIVGSGMIGAPGVAARFFQALATAKIN
IQMITTSEIKISCVVPETQGQAALKLVHEAFALGGEAKVEVPA

Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]

COG id: COG0527

COG function: function code E; Aspartokinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ACT domains [H]

Homologues:

Organism=Escherichia coli, GI1786183, Length=287, Percent_Identity=32.7526132404181, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790455, Length=185, Percent_Identity=38.3783783783784, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790376, Length=288, Percent_Identity=27.7777777777778, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320893, Length=383, Percent_Identity=26.3707571801567, Blast_Score=97, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001048
- InterPro:   IPR005260
- InterPro:   IPR001341
- InterPro:   IPR018042 [H]

Pfam domain/function: PF00696 AA_kinase; PF01842 ACT [H]

EC number: =2.7.2.4 [H]

Molecular weight: Translated: 63602; Mature: 63471

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00324 ASPARTOKINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMIVQKYGGTSVGSVERIQAVAKRVQQRAQAGNQIVVVVSAMGKTTDGLVKLAHEISTN
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCC
PNRREMDMLLSTGEQVSISLLSMALQELGQPAISLTGAQVGIVTEAEHSRARILEIKTDR
CCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEECCCEEEEEECCCCCCEEEEEEEHHH
LQRHLQKGEVIVVAGFQGISKTEDLEITTLGRGGSDTSAVAIAAALKASCCEIYTDVPGI
HHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
LTTDPRIVPEAQLMAEVTSDEMLELASLGAKVLHPRAVEIAKNYGVPLVVRSSWTEDPGT
EECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHCCCCCEEEECCCCCCCCC
WVTSAPVSDRPLINLEIAKAVDAVEFDTNQARIAMLHIPDRPGVAAKLFGEIATHNVDVD
EEEECCCCCCCEEEEEHHHHHHHEEECCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCHH
LIIQSIHDGNSNDIAFTVTENAATQAQAIAEAIAPTLCAGTDQDLSDVAVMSANDIAKIT
EEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHEEEECCCCEEEEE
ISGAGMIGRPGIAATMFQSLADAGINIEMISTSEVKVSCVIQQTDCDRAIATLCDVFDIA
EECCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCEEEEEEEEECCHHHHHHHHHHHHHHC
SSPMNATPAALNPEDHPPVRGVALDLKQAQLAIRHVPDSPGMAAQIFSLLAHQNISVDMI
CCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCEEEE
IQSQRCRVLNGVKTRDIAFTVAQGDAEAARLALSSMAEQLNFGEIEVDPAIAKVSIVGSG
EECCCHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCEEEEEEEECC
MIGAPGVAARFFQALATAKINIQMITTSEIKISCVVPETQGQAALKLVHEAFALGGEAKV
CCCCCHHHHHHHHHHHHEEEEEEEEEECCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEE
EVPA
ECCC
>Mature Secondary Structure 
AMIVQKYGGTSVGSVERIQAVAKRVQQRAQAGNQIVVVVSAMGKTTDGLVKLAHEISTN
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCC
PNRREMDMLLSTGEQVSISLLSMALQELGQPAISLTGAQVGIVTEAEHSRARILEIKTDR
CCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEECCCEEEEEECCCCCCEEEEEEEHHH
LQRHLQKGEVIVVAGFQGISKTEDLEITTLGRGGSDTSAVAIAAALKASCCEIYTDVPGI
HHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
LTTDPRIVPEAQLMAEVTSDEMLELASLGAKVLHPRAVEIAKNYGVPLVVRSSWTEDPGT
EECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHCCCCCEEEECCCCCCCCC
WVTSAPVSDRPLINLEIAKAVDAVEFDTNQARIAMLHIPDRPGVAAKLFGEIATHNVDVD
EEEECCCCCCCEEEEEHHHHHHHEEECCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCHH
LIIQSIHDGNSNDIAFTVTENAATQAQAIAEAIAPTLCAGTDQDLSDVAVMSANDIAKIT
EEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHEEEECCCCEEEEE
ISGAGMIGRPGIAATMFQSLADAGINIEMISTSEVKVSCVIQQTDCDRAIATLCDVFDIA
EECCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCEEEEEEEEECCHHHHHHHHHHHHHHC
SSPMNATPAALNPEDHPPVRGVALDLKQAQLAIRHVPDSPGMAAQIFSLLAHQNISVDMI
CCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCEEEE
IQSQRCRVLNGVKTRDIAFTVAQGDAEAARLALSSMAEQLNFGEIEVDPAIAKVSIVGSG
EECCCHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCEEEEEEEECC
MIGAPGVAARFFQALATAKINIQMITTSEIKISCVVPETQGQAALKLVHEAFALGGEAKV
CCCCCHHHHHHHHHHHHEEEEEEEEEECCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEE
EVPA
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1444390 [H]