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The map label for this gene is dnaN [H]

Identifier: 170077879

GI number: 170077879

Start: 1308995

End: 1310179

Strand: Reverse

Name: dnaN [H]

Synonym: SYNPCC7002_A1263

Alternate gene names: 170077879

Gene position: 1310179-1308995 (Counterclockwise)

Preceding gene: 170077882

Following gene: 170077877

Centisome position: 43.56

GC content: 52.41

Gene sequence:

>1185_bases
ATGAAGTTTGTTTGCAGTCAAAGTGATCTAAATAGCCAACTGTCCCTCGTCGGTCGGGCGGTGCCCTCGCGGCCTACCCA
CCCTATTTTGGGAAATGTGCTGTTGACTGCGGATGCGAACCGCCATCAGATTCAACTCACCGCTTTTGATCTCAGCCTCG
GCATTCGCACGAGTTTTCCGGCCCAAGTTATCGAAGGGGGCACCCTAACCCTGCCAGCAAAGTTGCTCAATGATATTGTG
TCGCGTCTGCCTGAGGGGGAAGTGACCTTGAGTTGCCCGTCGGATACTTTGATGAAAGGTGATGCCCAGGCGACCCTAAC
TGCTGCGACGGGACGGTTTCAGATTCGAGGCATGGGGGCCGAGGAATTCCCAGAATTACCAACGATCCAGGACGGTAAAA
AATTAATGTTGCCGGCGATCGCCTTGAGTGAAGGCCTAGGAGGTGTACTATTCGCTGCAAGCCCCGATGAAACCAAGCAA
GTTCTCACGGGCGTCCATCTCACCCATCACCAGGATTGCCTTGAGTTTGCCGCGACCGATGGCCACCGTCTTGCTCTCGT
TGAAACCAGTGATCAGGTCAGTCCAGAGCCAGAATCCAGCGAAACCGGTAAACTTCCCACCTCAACCCTGGAAGATTTTG
CTTTAACCATCCCCGCCCGGGCGCTCCGAGAACTAGAACGAATGTTGACCACCGCCAATGAAGCGGATTTGATTGCCTTG
CATTTAGACGATAGCCAAGTCATTTTTGAAGTCAATCACCAGCACCTCACCAGCCGTAAACTAGACGGTGCCTACCCCGC
TTACCACCAGTTAATCCCCCGCCAGTTTAGCCGCGATGTCACCCTAGAGCGACGGGCTTTGATTAGCAGCATTGAACGGG
TGGCGGTTCTGGCCGATCAAAAAAATAATATTGTCAAATTCCGCCTCAACAGCGCCGAACAAAAACTTCACCTCGCTGTG
GAAGCCCAGGATGTGGGCAGTGGTGAAGAAGCGTTGCCCGCCCAGGTTTCAGGGACAGACCTAGAGATCGCTTTTAACGT
GAGGTATCTCATCGATGGTCTGAAGGCTTTACCGAGTAATGAGATCAAGATGCAGTTGAATGAGAATAACCAGCCAGTCA
TTTTTACGCCCCTGGGTGCAGTGCAAATGACTTATTTGATTATGCCCGTGCAGATCCGCAGTTAA

Upstream 100 bases:

>100_bases
ATCGGGTATTGCGCCATCGCCGCCCCAGAAAAAATCCCGCCGGCTAGGGGATGTTGTAGTAGAATCTATCTGCTCTGCTT
GGAGATCTCCGGAAAAAGCC

Downstream 100 bases:

>100_bases
GGCGTTGGGGCTGGGGCTGTCTCTGGGGCGGCTGGTTGGCTAGGCGCTTGGATAATCTCTTTTTTAGCCATGTGGTCATA
GAATTGACGACTAATTTTGT

Product: DNA polymerase III subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKFVCSQSDLNSQLSLVGRAVPSRPTHPILGNVLLTADANRHQIQLTAFDLSLGIRTSFPAQVIEGGTLTLPAKLLNDIV
SRLPEGEVTLSCPSDTLMKGDAQATLTAATGRFQIRGMGAEEFPELPTIQDGKKLMLPAIALSEGLGGVLFAASPDETKQ
VLTGVHLTHHQDCLEFAATDGHRLALVETSDQVSPEPESSETGKLPTSTLEDFALTIPARALRELERMLTTANEADLIAL
HLDDSQVIFEVNHQHLTSRKLDGAYPAYHQLIPRQFSRDVTLERRALISSIERVAVLADQKNNIVKFRLNSAEQKLHLAV
EAQDVGSGEEALPAQVSGTDLEIAFNVRYLIDGLKALPSNEIKMQLNENNQPVIFTPLGAVQMTYLIMPVQIRS

Sequences:

>Translated_394_residues
MKFVCSQSDLNSQLSLVGRAVPSRPTHPILGNVLLTADANRHQIQLTAFDLSLGIRTSFPAQVIEGGTLTLPAKLLNDIV
SRLPEGEVTLSCPSDTLMKGDAQATLTAATGRFQIRGMGAEEFPELPTIQDGKKLMLPAIALSEGLGGVLFAASPDETKQ
VLTGVHLTHHQDCLEFAATDGHRLALVETSDQVSPEPESSETGKLPTSTLEDFALTIPARALRELERMLTTANEADLIAL
HLDDSQVIFEVNHQHLTSRKLDGAYPAYHQLIPRQFSRDVTLERRALISSIERVAVLADQKNNIVKFRLNSAEQKLHLAV
EAQDVGSGEEALPAQVSGTDLEIAFNVRYLIDGLKALPSNEIKMQLNENNQPVIFTPLGAVQMTYLIMPVQIRS
>Mature_394_residues
MKFVCSQSDLNSQLSLVGRAVPSRPTHPILGNVLLTADANRHQIQLTAFDLSLGIRTSFPAQVIEGGTLTLPAKLLNDIV
SRLPEGEVTLSCPSDTLMKGDAQATLTAATGRFQIRGMGAEEFPELPTIQDGKKLMLPAIALSEGLGGVLFAASPDETKQ
VLTGVHLTHHQDCLEFAATDGHRLALVETSDQVSPEPESSETGKLPTSTLEDFALTIPARALRELERMLTTANEADLIAL
HLDDSQVIFEVNHQHLTSRKLDGAYPAYHQLIPRQFSRDVTLERRALISSIERVAVLADQKNNIVKFRLNSAEQKLHLAV
EAQDVGSGEEALPAQVSGTDLEIAFNVRYLIDGLKALPSNEIKMQLNENNQPVIFTPLGAVQMTYLIMPVQIRS

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped

COG id: COG0592

COG function: function code L; DNA polymerase sliding clamp subunit (PCNA homolog)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790136, Length=396, Percent_Identity=26.5151515151515, Blast_Score=125, Evalue=6e-30,

Paralogues:

None

Copy number: 5954 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001001
- InterPro:   IPR022635
- InterPro:   IPR022637
- InterPro:   IPR022634 [H]

Pfam domain/function: PF00712 DNA_pol3_beta; PF02767 DNA_pol3_beta_2; PF02768 DNA_pol3_beta_3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 42916; Mature: 42916

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVCSQSDLNSQLSLVGRAVPSRPTHPILGNVLLTADANRHQIQLTAFDLSLGIRTSFP
CCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEEEECCCCCCC
AQVIEGGTLTLPAKLLNDIVSRLPEGEVTLSCPSDTLMKGDAQATLTAATGRFQIRGMGA
HHHHCCCCEEECHHHHHHHHHHCCCCCEEEECCCCHHCCCCCCEEEEEECCEEEEEECCH
EEFPELPTIQDGKKLMLPAIALSEGLGGVLFAASPDETKQVLTGVHLTHHQDCLEFAATD
HHCCCCCCCCCCCEEEEHHHHHHCCCCEEEEECCCCHHHHHHHCCCHHHHHHHHHHHCCC
GHRLALVETSDQVSPEPESSETGKLPTSTLEDFALTIPARALRELERMLTTANEADLIAL
CCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHEECCHHHHHHHHHHHHCCCCCCEEEE
HLDDSQVIFEVNHQHLTSRKLDGAYPAYHQLIPRQFSRDVTLERRALISSIERVAVLADQ
EECCCEEEEEECCHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEECC
KNNIVKFRLNSAEQKLHLAVEAQDVGSGEEALPAQVSGTDLEIAFNVRYLIDGLKALPSN
CCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCCEECCCEEEEEEEHHHHHHHHHHCCCC
EIKMQLNENNQPVIFTPLGAVQMTYLIMPVQIRS
CEEEEECCCCCCEEEECCCHHEEEEEEEEEEECC
>Mature Secondary Structure
MKFVCSQSDLNSQLSLVGRAVPSRPTHPILGNVLLTADANRHQIQLTAFDLSLGIRTSFP
CCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEEEECCCCCCC
AQVIEGGTLTLPAKLLNDIVSRLPEGEVTLSCPSDTLMKGDAQATLTAATGRFQIRGMGA
HHHHCCCCEEECHHHHHHHHHHCCCCCEEEECCCCHHCCCCCCEEEEEECCEEEEEECCH
EEFPELPTIQDGKKLMLPAIALSEGLGGVLFAASPDETKQVLTGVHLTHHQDCLEFAATD
HHCCCCCCCCCCCEEEEHHHHHHCCCCEEEEECCCCHHHHHHHCCCHHHHHHHHHHHCCC
GHRLALVETSDQVSPEPESSETGKLPTSTLEDFALTIPARALRELERMLTTANEADLIAL
CCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHEECCHHHHHHHHHHHHCCCCCCEEEE
HLDDSQVIFEVNHQHLTSRKLDGAYPAYHQLIPRQFSRDVTLERRALISSIERVAVLADQ
EECCCEEEEEECCHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEECC
KNNIVKFRLNSAEQKLHLAVEAQDVGSGEEALPAQVSGTDLEIAFNVRYLIDGLKALPSN
CCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCCEECCCEEEEEEEHHHHHHHHHHCCCC
EIKMQLNENNQPVIFTPLGAVQMTYLIMPVQIRS
CEEEEECCCCCCEEEECCCHHEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]