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The map label for this gene is pdhB [H]

Identifier: 170077278

GI number: 170077278

Start: 686661

End: 687644

Strand: Direct

Name: pdhB [H]

Synonym: SYNPCC7002_A0655

Alternate gene names: 170077278

Gene position: 686661-687644 (Clockwise)

Preceding gene: 170077270

Following gene: 170077279

Centisome position: 22.83

GC content: 51.32

Gene sequence:

>984_bases
ATGGCGGAAACTTTACTTTTTAATGCGCTGCGTCAAGCTATCGATGAAGAGATGGCACGTGACGAAACTGTCTTCGTTAT
GGGCGAAGATGTGGGTCATTACGGCGGTTCCTACAAGGTAACGAAGGATCTTGCGAAAAAATATGGTGACCTGCGCGTTC
TGGATACACCCATCGCAGAAAACAGCTTCACCGGGATGGCTGTTGGCGCCGCCATGACTGGGCTACGGCCAATCATCGAA
GGGATGAATATGGGCTTTTTGCTGTTGGCCTTCAACCAAATTTCCAATAACGCTGGGATGTTGCGCTACACATCCGGCGG
TAATTTCACAATTCCAATGGTGATCCGGGGGCCTGGAGGTGTCGGTCGGCAGTTGGGGGCAGAACACTCTCAGCGGCTAG
AAGCCTACTTCCAAGCTGTCCCTGGCTTGAAGATCGTGGCCTGTTCTACCCCTTACAATGCCAAGGGTTTATTAAAGGCG
GCAATCCGTGACGAAAACCCCGTCCTTTTCTTTGAACACGTGCTGCTCTACAACCTAAAAGAGAATTTGCCCGATGGGGA
ATATGTGCTGCCCCTCGATAAGGCGGAGTTGGTGCGGGAAGGGAAAGATGTGACGATTTTGACCTATTCGCGGATGCGTC
ACCATTGCACCCAGGCGATTAAAACCCTCGAAAAACAAGGTATCGATCCAGAATTAATTGATCTAATCTCCCTGAAGCCC
ATCGACATGGAGGCGATCGCCAAATCCGTGAAGAAAACCCACCGGGTGATCATCGTCGAAGAATGTATGAAAACGGCGGG
GATTGCGGCGGAAGTGATGTCCTTGATCAACGAGCAACTGTTTGACGAATTAGATGCCCCCGTAATGCGTCTCTCGTCCC
AGGATATTCCCACCCCCTACAACGGCACCCTGGAGCGACTCACCATCGTCCAACCGGACAACATCGTCGAAGCAGTGCAA
AATATGTTGGCCCTGAACGTCTAA

Upstream 100 bases:

>100_bases
CTAAAAATATCGGCTTCAATCCCACCTAGATTGATGGCGCAAGAAAGGCTCAGGAATGATACGATGTCACTTGCTGCGAT
AGGTTTTAGAACGATTTCAT

Downstream 100 bases:

>100_bases
ACACCAGCGACCAACTGCGGTTCATCCTCCTAGATCCATCATGCAAAAACAACGGTTAATCATAGTTGCAATTCTTTTTT
TGGTGGCGATCGCCATCACG

Product: pyruvate dehydrogenase E1 beta chain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MAETLLFNALRQAIDEEMARDETVFVMGEDVGHYGGSYKVTKDLAKKYGDLRVLDTPIAENSFTGMAVGAAMTGLRPIIE
GMNMGFLLLAFNQISNNAGMLRYTSGGNFTIPMVIRGPGGVGRQLGAEHSQRLEAYFQAVPGLKIVACSTPYNAKGLLKA
AIRDENPVLFFEHVLLYNLKENLPDGEYVLPLDKAELVREGKDVTILTYSRMRHHCTQAIKTLEKQGIDPELIDLISLKP
IDMEAIAKSVKKTHRVIIVEECMKTAGIAAEVMSLINEQLFDELDAPVMRLSSQDIPTPYNGTLERLTIVQPDNIVEAVQ
NMLALNV

Sequences:

>Translated_327_residues
MAETLLFNALRQAIDEEMARDETVFVMGEDVGHYGGSYKVTKDLAKKYGDLRVLDTPIAENSFTGMAVGAAMTGLRPIIE
GMNMGFLLLAFNQISNNAGMLRYTSGGNFTIPMVIRGPGGVGRQLGAEHSQRLEAYFQAVPGLKIVACSTPYNAKGLLKA
AIRDENPVLFFEHVLLYNLKENLPDGEYVLPLDKAELVREGKDVTILTYSRMRHHCTQAIKTLEKQGIDPELIDLISLKP
IDMEAIAKSVKKTHRVIIVEECMKTAGIAAEVMSLINEQLFDELDAPVMRLSSQDIPTPYNGTLERLTIVQPDNIVEAVQ
NMLALNV
>Mature_326_residues
AETLLFNALRQAIDEEMARDETVFVMGEDVGHYGGSYKVTKDLAKKYGDLRVLDTPIAENSFTGMAVGAAMTGLRPIIEG
MNMGFLLLAFNQISNNAGMLRYTSGGNFTIPMVIRGPGGVGRQLGAEHSQRLEAYFQAVPGLKIVACSTPYNAKGLLKAA
IRDENPVLFFEHVLLYNLKENLPDGEYVLPLDKAELVREGKDVTILTYSRMRHHCTQAIKTLEKQGIDPELIDLISLKPI
DMEAIAKSVKKTHRVIIVEECMKTAGIAAEVMSLINEQLFDELDAPVMRLSSQDIPTPYNGTLERLTIVQPDNIVEAVQN
MLALNV

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG0022

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI156564403, Length=321, Percent_Identity=42.0560747663551, Blast_Score=276, Evalue=2e-74,
Organism=Homo sapiens, GI291084858, Length=321, Percent_Identity=39.8753894080997, Blast_Score=252, Evalue=4e-67,
Organism=Homo sapiens, GI4557353, Length=321, Percent_Identity=37.3831775700935, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI34101272, Length=321, Percent_Identity=37.3831775700935, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17538422, Length=323, Percent_Identity=45.5108359133127, Blast_Score=291, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI17506935, Length=298, Percent_Identity=36.241610738255, Blast_Score=183, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6319698, Length=323, Percent_Identity=43.343653250774, Blast_Score=276, Evalue=3e-75,
Organism=Drosophila melanogaster, GI21358145, Length=321, Percent_Identity=42.9906542056075, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24650940, Length=321, Percent_Identity=42.9906542056075, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI160714832, Length=298, Percent_Identity=38.9261744966443, Blast_Score=203, Evalue=1e-52,
Organism=Drosophila melanogaster, GI160714828, Length=298, Percent_Identity=38.9261744966443, Blast_Score=203, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24650943, Length=86, Percent_Identity=54.6511627906977, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24650945, Length=86, Percent_Identity=54.6511627906977, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000089
- InterPro:   IPR011053
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 36070; Mature: 35939

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETLLFNALRQAIDEEMARDETVFVMGEDVGHYGGSYKVTKDLAKKYGDLRVLDTPIAE
CCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEHHHHHHHCCCEEEEECCCCC
NSFTGMAVGAAMTGLRPIIEGMNMGFLLLAFNQISNNAGMLRYTSGGNFTIPMVIRGPGG
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCEEEEECCCCEEEEEEEECCCC
VGRQLGAEHSQRLEAYFQAVPGLKIVACSTPYNAKGLLKAAIRDENPVLFFEHVLLYNLK
CCHHHCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCCEEHHHHHHHHHHH
ENLPDGEYVLPLDKAELVREGKDVTILTYSRMRHHCTQAIKTLEKQGIDPELIDLISLKP
HCCCCCCEEECCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
IDMEAIAKSVKKTHRVIIVEECMKTAGIAAEVMSLINEQLFDELDAPVMRLSSQDIPTPY
CCHHHHHHHHHHHHCEEEHHHHHHHHCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCC
NGTLERLTIVQPDNIVEAVQNMLALNV
CCCEEEEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AETLLFNALRQAIDEEMARDETVFVMGEDVGHYGGSYKVTKDLAKKYGDLRVLDTPIAE
CHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEHHHHHHHCCCEEEEECCCCC
NSFTGMAVGAAMTGLRPIIEGMNMGFLLLAFNQISNNAGMLRYTSGGNFTIPMVIRGPGG
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCEEEEECCCCEEEEEEEECCCC
VGRQLGAEHSQRLEAYFQAVPGLKIVACSTPYNAKGLLKAAIRDENPVLFFEHVLLYNLK
CCHHHCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCCEEHHHHHHHHHHH
ENLPDGEYVLPLDKAELVREGKDVTILTYSRMRHHCTQAIKTLEKQGIDPELIDLISLKP
HCCCCCCEEECCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
IDMEAIAKSVKKTHRVIIVEECMKTAGIAAEVMSLINEQLFDELDAPVMRLSSQDIPTPY
CCHHHHHHHHHHHHCEEEHHHHHHHHCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCC
NGTLERLTIVQPDNIVEAVQNMLALNV
CCCEEEEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9515924 [H]