Click here to switch to the map view.

The map label for this gene is cph1 [H]

Identifier: 170076923

GI number: 170076923

Start: 312347

End: 313519

Strand: Direct

Name: cph1 [H]

Synonym: SYNPCC7002_A0295

Alternate gene names: 170076923

Gene position: 312347-313519 (Clockwise)

Preceding gene: 170076911

Following gene: 170076924

Centisome position: 10.38

GC content: 47.4

Gene sequence:

>1173_bases
ATGCACTTAGATGATCTACATATTCTGCTCATTGAAGATAATTTGGCGGAAGCTGAATTGTTAGGGGATCTACTGGCAGA
TATTGAGATGGTGCAGTGCGATATTGTGCATTTTGCCCACCTCGAAAAGGCGATCGCCTGTCTTGAAGACCAAACCTTTG
ACGTGATTTTGCTCGATTTGAGCTTGCCCGACAGCCAGGGCCTAAGCTCTCTCCCGATGCTGATGGGCATTGCTCCGGAC
GTTCCCATTGTGGTGCTGACGAATACCAATGATGCCGAGTTAGCCCTCGAAGCGGTGCACCAAGGAGCCCAGGATTATTT
AATCAAAAAAAATATCGCCTTTGACCAAGAGACATTACTCCGCTCAATTCTCTACGCCATCGAACGCAAGCGAAATCAAC
AGGCCCTCAAGTTAGCCAACGAGCGACTCCGGCAAGAGATGAAGGCCCGCGAAGCAATGCAGATCAAACTTGAACAATCC
AACCAGGAGCTTGAACAGTTTGCCTATATTGCCTCCCACGATTTGAAGCAACCCTTAGCGAGTATTTACTCTTGGTCTCA
ACTGCTCCAGGTGCGCTACGGCAATTGTCTGGATGAAAAAGGGAGTAGTTACCTCAATGCGATCCAAGATTCCGTGCGCC
AGATGACCCAGCTCATTGAAGATCTTTTAACCTATTCGCGGGTCGATCGAGTAGAAAATACGGCGGTGGACGTAGATTGT
AATTTGATCGTCCATCAGGTTTGTAATCGACTCAGTTCGGCGATCGCCCAACAAAGCGCCAAGCTCACCATTGATTCCTT
GCCCACCATTCAGGGAAATCCTCTACAAATCAGTCAAATTTTCCAAAATTTAATCGAAAATGCCCTCAAATATTGCCGGG
AAGAGGTGCCCCCCCAGATTCGGATCAGTGCCGTCCAAAACGATAACCACTGGGTTTTTAGCTGCCACGACAATGGCATT
GGCATTGAAGCCGATTATTTTGAGCAAATTTTCTACGCTTTTAAACGCCTCCATTCCCAGAGTCAATATTCCGGGACAGG
CATTGGCCTCGCCGTCTGTAAAAAAATTGTGCGCCGTTATGGTGGTGAAATTTGGTTGACTTCTACCTTTGGTGAAGGCT
CTACTTTTTACTTTTCCTTTCCGATGCAATCTTCCCCCAAGGACAATGCCTAG

Upstream 100 bases:

>100_bases
GTAGGCGAGTAACGGCCACTTTTCAAGGGAAAAGCCTGGGGTGAAAAAGCGAGATTGCAAGTGAATTTGGCCTGACTTCC
CCAACTGTCGCGACTAAACT

Downstream 100 bases:

>100_bases
GAAGCAGCTCTAGGGTATCTGCGAGGGAGTTTGATCAAGTTACAATAAAGCTGACCCAGACCTAGTTGATTTCACCTGAT
ACAGACACCGTGACTATTTC

Product: two-component hybrid sensor and regulator

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MHLDDLHILLIEDNLAEAELLGDLLADIEMVQCDIVHFAHLEKAIACLEDQTFDVILLDLSLPDSQGLSSLPMLMGIAPD
VPIVVLTNTNDAELALEAVHQGAQDYLIKKNIAFDQETLLRSILYAIERKRNQQALKLANERLRQEMKAREAMQIKLEQS
NQELEQFAYIASHDLKQPLASIYSWSQLLQVRYGNCLDEKGSSYLNAIQDSVRQMTQLIEDLLTYSRVDRVENTAVDVDC
NLIVHQVCNRLSSAIAQQSAKLTIDSLPTIQGNPLQISQIFQNLIENALKYCREEVPPQIRISAVQNDNHWVFSCHDNGI
GIEADYFEQIFYAFKRLHSQSQYSGTGIGLAVCKKIVRRYGGEIWLTSTFGEGSTFYFSFPMQSSPKDNA

Sequences:

>Translated_390_residues
MHLDDLHILLIEDNLAEAELLGDLLADIEMVQCDIVHFAHLEKAIACLEDQTFDVILLDLSLPDSQGLSSLPMLMGIAPD
VPIVVLTNTNDAELALEAVHQGAQDYLIKKNIAFDQETLLRSILYAIERKRNQQALKLANERLRQEMKAREAMQIKLEQS
NQELEQFAYIASHDLKQPLASIYSWSQLLQVRYGNCLDEKGSSYLNAIQDSVRQMTQLIEDLLTYSRVDRVENTAVDVDC
NLIVHQVCNRLSSAIAQQSAKLTIDSLPTIQGNPLQISQIFQNLIENALKYCREEVPPQIRISAVQNDNHWVFSCHDNGI
GIEADYFEQIFYAFKRLHSQSQYSGTGIGLAVCKKIVRRYGGEIWLTSTFGEGSTFYFSFPMQSSPKDNA
>Mature_390_residues
MHLDDLHILLIEDNLAEAELLGDLLADIEMVQCDIVHFAHLEKAIACLEDQTFDVILLDLSLPDSQGLSSLPMLMGIAPD
VPIVVLTNTNDAELALEAVHQGAQDYLIKKNIAFDQETLLRSILYAIERKRNQQALKLANERLRQEMKAREAMQIKLEQS
NQELEQFAYIASHDLKQPLASIYSWSQLLQVRYGNCLDEKGSSYLNAIQDSVRQMTQLIEDLLTYSRVDRVENTAVDVDC
NLIVHQVCNRLSSAIAQQSAKLTIDSLPTIQGNPLQISQIFQNLIENALKYCREEVPPQIRISAVQNDNHWVFSCHDNGI
GIEADYFEQIFYAFKRLHSQSQYSGTGIGLAVCKKIVRRYGGEIWLTSTFGEGSTFYFSFPMQSSPKDNA

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=250, Percent_Identity=28.4, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081816, Length=274, Percent_Identity=25.5474452554745, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790861, Length=233, Percent_Identity=29.1845493562232, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1789149, Length=271, Percent_Identity=23.9852398523985, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693157, Length=273, Percent_Identity=24.9084249084249, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790436, Length=249, Percent_Identity=25.7028112449799, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788713, Length=254, Percent_Identity=25.5905511811024, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786600, Length=246, Percent_Identity=27.6422764227642, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788549, Length=250, Percent_Identity=24.4, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=27.3542600896861, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786912, Length=226, Percent_Identity=26.5486725663717, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788393, Length=235, Percent_Identity=26.8085106382979, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790346, Length=200, Percent_Identity=25.5, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789808, Length=211, Percent_Identity=24.6445497630332, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44070; Mature: 44070

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLDDLHILLIEDNLAEAELLGDLLADIEMVQCDIVHFAHLEKAIACLEDQTFDVILLDL
CCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
SLPDSQGLSSLPMLMGIAPDVPIVVLTNTNDAELALEAVHQGAQDYLIKKNIAFDQETLL
CCCCCCCCCHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHCCCCCCHHHHH
RSILYAIERKRNQQALKLANERLRQEMKAREAMQIKLEQSNQELEQFAYIASHDLKQPLA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIYSWSQLLQVRYGNCLDEKGSSYLNAIQDSVRQMTQLIEDLLTYSRVDRVENTAVDVDC
HHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHH
NLIVHQVCNRLSSAIAQQSAKLTIDSLPTIQGNPLQISQIFQNLIENALKYCREEVPPQI
HHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCE
RISAVQNDNHWVFSCHDNGIGIEADYFEQIFYAFKRLHSQSQYSGTGIGLAVCKKIVRRY
EEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
GGEIWLTSTFGEGSTFYFSFPMQSSPKDNA
CCCEEEEEECCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MHLDDLHILLIEDNLAEAELLGDLLADIEMVQCDIVHFAHLEKAIACLEDQTFDVILLDL
CCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
SLPDSQGLSSLPMLMGIAPDVPIVVLTNTNDAELALEAVHQGAQDYLIKKNIAFDQETLL
CCCCCCCCCHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHCCCCCCHHHHH
RSILYAIERKRNQQALKLANERLRQEMKAREAMQIKLEQSNQELEQFAYIASHDLKQPLA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIYSWSQLLQVRYGNCLDEKGSSYLNAIQDSVRQMTQLIEDLLTYSRVDRVENTAVDVDC
HHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHH
NLIVHQVCNRLSSAIAQQSAKLTIDSLPTIQGNPLQISQIFQNLIENALKYCREEVPPQI
HHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCE
RISAVQNDNHWVFSCHDNGIGIEADYFEQIFYAFKRLHSQSQYSGTGIGLAVCKKIVRRY
EEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
GGEIWLTSTFGEGSTFYFSFPMQSSPKDNA
CCCEEEEEECCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]