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The map label for this gene is trpB [H]

Identifier: 170076924

GI number: 170076924

Start: 313609

End: 314862

Strand: Direct

Name: trpB [H]

Synonym: SYNPCC7002_A0296

Alternate gene names: 170076924

Gene position: 313609-314862 (Clockwise)

Preceding gene: 170076923

Following gene: 170076928

Centisome position: 10.43

GC content: 53.91

Gene sequence:

>1254_bases
GTGACTATTTCTCCCATTTCTCCCCAAGACACTACCTTTAACCCCAATCAACCCGATGCCTTTGGGCGTTTTGGGAAATA
TGGTGGTAAATATGTGCCTGAAACCTTGATGCCCGCTTTGGCTGAGTTAGAAGCGGCCTATGCCCAGTATCGTAACGACC
CGACTTTTCAAGCAGAATTAGCTGGGCTGCTAAAAGATTATGTTGGTCGCCCCAGTCCCCTTTATTTCGCGGAACGGCTG
ACGGCTCGCTATGCTCGCCCCGATGGTTCTGGCCCGCAAATTTACCTGAAACGGGAGGATCTCAACCACACGGGTGCCCA
CAAAATCAATAATGCGATCGCCCAGGCCCTACTCGCCAAACGTATGGGCAAAAAACGCATCATCGCCGAAACTGGTGCGG
GTCAACATGGCGTTGCCACAGCGACGGTCTGTGCCCGGTTTGGGTTGGAATGCATTATCTATATGGGGGTGCAGGACATG
GAACGCCAAGCCCTCAACGTCTTCCGGATGAAATTATTAGGGGCCACCGTCCAACCCGTAGAAGCGGGCACTGGAACCCT
CAAAGATGCCACCTCCGAGGCCATTCGGGACTGGGTAACAAATGTAGAGACAACCCACTATATCCTCGGTTCCGTAGCTG
GCCCCCACCCCTACCCGATGATGGTGCGAGATTTCCACGCGATCATTGGTGCCGAAACTCGCCAACAATGTGCAGAAAAG
TGGGGTGGCCTCCCGGATATTCTGATTGCCTGTGTGGGGGGAGGTTCCAATGCCATGGGGCTTTTCCACGAATTTGTTAA
AGATTCGACTGTGCGCTTGATTGGCGTTGAGGCCGAAGGGTCTGGGATCACCAGTGGTCACCACGCGGCTACCCTCACCC
AAGGGAAACCAGGGGTCCTACATGGGGCCATGAGCTACCTATTGCAAGACACCGAAGGCCAAGTTGTCGAGGCCCATTCC
ATCAGTGCGGGCTTAGATTATCCTGGCGTCGGCCCGGAACACAGCTACCTCAAAGATACTTGTCGGGCTGAATATTACAG
TGTCACCGACCAGGATGCAGTGGCTGCCTTCCGACGGGTGTCCGAGTTAGAAGGAATTATTCCCGCCCTGGAAACCTCCC
ATGCCTTTGCTTATTTAGAAACCCTTTGTCCCCAGTTGTCGGGCAGTCCGCGCATTGTGATCAACAGTTCTGGTCGGGGT
GATAAGGATGTACAAACGGTGGCAAAGTATCTCGATCGCCATGGTTGGGACTAA

Upstream 100 bases:

>100_bases
ACAATGCCTAGGAAGCAGCTCTAGGGTATCTGCGAGGGAGTTTGATCAAGTTACAATAAAGCTGACCCAGACCTAGTTGA
TTTCACCTGATACAGACACC

Downstream 100 bases:

>100_bases
AGAAATTCGAGATTAAAGTCTAAATTGCGGTAAACAACGAGGGGGATTGATTGTAATCCCTCTTTTTTTGTGGCTACCAA
TGGATCTGACTCAGGATGTA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MTISPISPQDTTFNPNQPDAFGRFGKYGGKYVPETLMPALAELEAAYAQYRNDPTFQAELAGLLKDYVGRPSPLYFAERL
TARYARPDGSGPQIYLKREDLNHTGAHKINNAIAQALLAKRMGKKRIIAETGAGQHGVATATVCARFGLECIIYMGVQDM
ERQALNVFRMKLLGATVQPVEAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAIIGAETRQQCAEK
WGGLPDILIACVGGGSNAMGLFHEFVKDSTVRLIGVEAEGSGITSGHHAATLTQGKPGVLHGAMSYLLQDTEGQVVEAHS
ISAGLDYPGVGPEHSYLKDTCRAEYYSVTDQDAVAAFRRVSELEGIIPALETSHAFAYLETLCPQLSGSPRIVINSSGRG
DKDVQTVAKYLDRHGWD

Sequences:

>Translated_417_residues
MTISPISPQDTTFNPNQPDAFGRFGKYGGKYVPETLMPALAELEAAYAQYRNDPTFQAELAGLLKDYVGRPSPLYFAERL
TARYARPDGSGPQIYLKREDLNHTGAHKINNAIAQALLAKRMGKKRIIAETGAGQHGVATATVCARFGLECIIYMGVQDM
ERQALNVFRMKLLGATVQPVEAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAIIGAETRQQCAEK
WGGLPDILIACVGGGSNAMGLFHEFVKDSTVRLIGVEAEGSGITSGHHAATLTQGKPGVLHGAMSYLLQDTEGQVVEAHS
ISAGLDYPGVGPEHSYLKDTCRAEYYSVTDQDAVAAFRRVSELEGIIPALETSHAFAYLETLCPQLSGSPRIVINSSGRG
DKDVQTVAKYLDRHGWD
>Mature_416_residues
TISPISPQDTTFNPNQPDAFGRFGKYGGKYVPETLMPALAELEAAYAQYRNDPTFQAELAGLLKDYVGRPSPLYFAERLT
ARYARPDGSGPQIYLKREDLNHTGAHKINNAIAQALLAKRMGKKRIIAETGAGQHGVATATVCARFGLECIIYMGVQDME
RQALNVFRMKLLGATVQPVEAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAIIGAETRQQCAEKW
GGLPDILIACVGGGSNAMGLFHEFVKDSTVRLIGVEAEGSGITSGHHAATLTQGKPGVLHGAMSYLLQDTEGQVVEAHSI
SAGLDYPGVGPEHSYLKDTCRAEYYSVTDQDAVAAFRRVSELEGIIPALETSHAFAYLETLCPQLSGSPRIVINSSGRGD
KDVQTVAKYLDRHGWD

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=393, Percent_Identity=53.6895674300254, Blast_Score=427, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6321412, Length=400, Percent_Identity=57.25, Blast_Score=464, Evalue=1e-131,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 45144; Mature: 45012

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISPISPQDTTFNPNQPDAFGRFGKYGGKYVPETLMPALAELEAAYAQYRNDPTFQAEL
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
AGLLKDYVGRPSPLYFAERLTARYARPDGSGPQIYLKREDLNHTGAHKINNAIAQALLAK
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
RMGKKRIIAETGAGQHGVATATVCARFGLECIIYMGVQDMERQALNVFRMKLLGATVQPV
HCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCC
EAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAIIGAETRQQCAEK
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
WGGLPDILIACVGGGSNAMGLFHEFVKDSTVRLIGVEAEGSGITSGHHAATLTQGKPGVL
HCCCHHHHHEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEECCCCCCHH
HGAMSYLLQDTEGQVVEAHSISAGLDYPGVGPEHSYLKDTCRAEYYSVTDQDAVAAFRRV
HHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
SELEGIIPALETSHAFAYLETLCPQLSGSPRIVINSSGRGDKDVQTVAKYLDRHGWD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TISPISPQDTTFNPNQPDAFGRFGKYGGKYVPETLMPALAELEAAYAQYRNDPTFQAEL
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
AGLLKDYVGRPSPLYFAERLTARYARPDGSGPQIYLKREDLNHTGAHKINNAIAQALLAK
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
RMGKKRIIAETGAGQHGVATATVCARFGLECIIYMGVQDMERQALNVFRMKLLGATVQPV
HCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCC
EAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAIIGAETRQQCAEK
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
WGGLPDILIACVGGGSNAMGLFHEFVKDSTVRLIGVEAEGSGITSGHHAATLTQGKPGVL
HCCCHHHHHEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEECCCCCCHH
HGAMSYLLQDTEGQVVEAHSISAGLDYPGVGPEHSYLKDTCRAEYYSVTDQDAVAAFRRV
HHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
SELEGIIPALETSHAFAYLETLCPQLSGSPRIVINSSGRGDKDVQTVAKYLDRHGWD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]