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The map label for this gene is hoxU [H]

Identifier: 170076828

GI number: 170076828

Start: 208477

End: 209193

Strand: Direct

Name: hoxU [H]

Synonym: SYNPCC7002_A0197

Alternate gene names: 170076828

Gene position: 208477-209193 (Clockwise)

Preceding gene: 170076827

Following gene: 170076829

Centisome position: 6.93

GC content: 51.6

Gene sequence:

>717_bases
ATGGCAGTTAAAACTTTAACGATAAATGATCAGCTAATCAGCGCCCGCGCTGGGGAAACGATCCTTGAAGCCGCCCGTGA
TGCAGGGATTCACATTCCGACCCTGTGCCATCTGGAGGGGGTGTCCGATGTGGGAGCTTGTCGCCTCTGTCTCGTGGAAA
TTGAGGGGAGTAATAAACTCCAGCCCGCCTGTGTGACGGAGGTGATGGAGGGAATGGTCGTCCAGACCCACACAGAAAAA
TTAGAAGAATATCGTCGGATGACGGTGGAATTGCTCTTCGCGGAAGGGAACCATGTTTGTGCGGTCTGTGTGGCGAATGG
TAATTGTGAGTTACAGGATATGGCGGTAGAGGTGGGGATGGATCATTCGCGCTTTCCGTACCAATATCCAAAGCGGGAAG
TGGATATTTCCCACAAGCAATTTGGCATTGACCATAACCGTTGCATCCTCTGTACCCGCTGTGTTCGGGTCTGTGATGAG
ATCGAGGGGGCACACGTCTGGGATGTATCCAATCGGGGCGGTGAATCAAAAATTGTCTCCGGTTTAAATCAGCCTTGGGG
GGCGGTGGATGCCTGTACGAGTTGTGGCAAATGTGTGGATGCTTGTCCAACGGGATCGATTTTCCGCAAGGGAGCCACCG
TAGGCAGTAAACTCGGCGATCGCCAAAAACTTGAATTTTTAATTACCGCACGCACCAAAGGAGAGTGGACAAGATAA

Upstream 100 bases:

>100_bases
CGCGGAATATGATGCCCTCGTGGGGAGTAACGCCGATTAAATTTTTTTTTAATTCCCATGCAGTCCTTACAGAGAGAACC
TTAAGCAAAATCGCAAAACT

Downstream 100 bases:

>100_bases
TGGCGCAAGAAACCCAACAAAAAATTCGATTTGCAACAATTTGGTTGGCGGGTTGTTCCGGTTGCCACATGTCTTTTTTA
GACCTCGATGAATTTTTAAT

Product: bidirectional hydrogenase complex protein HoxU

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G 2; NDH-1 subunit G 2 [H]

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MAVKTLTINDQLISARAGETILEAARDAGIHIPTLCHLEGVSDVGACRLCLVEIEGSNKLQPACVTEVMEGMVVQTHTEK
LEEYRRMTVELLFAEGNHVCAVCVANGNCELQDMAVEVGMDHSRFPYQYPKREVDISHKQFGIDHNRCILCTRCVRVCDE
IEGAHVWDVSNRGGESKIVSGLNQPWGAVDACTSCGKCVDACPTGSIFRKGATVGSKLGDRQKLEFLITARTKGEWTR

Sequences:

>Translated_238_residues
MAVKTLTINDQLISARAGETILEAARDAGIHIPTLCHLEGVSDVGACRLCLVEIEGSNKLQPACVTEVMEGMVVQTHTEK
LEEYRRMTVELLFAEGNHVCAVCVANGNCELQDMAVEVGMDHSRFPYQYPKREVDISHKQFGIDHNRCILCTRCVRVCDE
IEGAHVWDVSNRGGESKIVSGLNQPWGAVDACTSCGKCVDACPTGSIFRKGATVGSKLGDRQKLEFLITARTKGEWTR
>Mature_237_residues
AVKTLTINDQLISARAGETILEAARDAGIHIPTLCHLEGVSDVGACRLCLVEIEGSNKLQPACVTEVMEGMVVQTHTEKL
EEYRRMTVELLFAEGNHVCAVCVANGNCELQDMAVEVGMDHSRFPYQYPKREVDISHKQFGIDHNRCILCTRCVRVCDEI
EGAHVWDVSNRGGESKIVSGLNQPWGAVDACTSCGKCVDACPTGSIFRKGATVGSKLGDRQKLEFLITARTKGEWTR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=222, Percent_Identity=31.981981981982, Blast_Score=114, Evalue=9e-26,
Organism=Escherichia coli, GI145693161, Length=211, Percent_Identity=30.8056872037915, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193209088, Length=222, Percent_Identity=29.7297297297297, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32566231, Length=207, Percent_Identity=30.9178743961353, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17565758, Length=222, Percent_Identity=29.7297297297297, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24640559, Length=207, Percent_Identity=31.8840579710145, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24640557, Length=207, Percent_Identity=31.8840579710145, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR000283
- InterPro:   IPR019574 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 26097; Mature: 25966

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
8.8 %Cys+Met (Translated Protein)
6.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKTLTINDQLISARAGETILEAARDAGIHIPTLCHLEGVSDVGACRLCLVEIEGSNKL
CCEEEEEECHHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCC
QPACVTEVMEGMVVQTHTEKLEEYRRMTVELLFAEGNHVCAVCVANGNCELQDMAVEVGM
CHHHHHHHHCCCEEEHHHHHHHHHHHHEEEEEEECCCEEEEEEEECCCCCHHHHHHHHCC
DHSRFPYQYPKREVDISHKQFGIDHNRCILCTRCVRVCDEIEGAHVWDVSNRGGESKIVS
CCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHH
GLNQPWGAVDACTSCGKCVDACPTGSIFRKGATVGSKLGDRQKLEFLITARTKGEWTR
CCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHCCCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure 
AVKTLTINDQLISARAGETILEAARDAGIHIPTLCHLEGVSDVGACRLCLVEIEGSNKL
CEEEEEECHHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEEEECCCCCC
QPACVTEVMEGMVVQTHTEKLEEYRRMTVELLFAEGNHVCAVCVANGNCELQDMAVEVGM
CHHHHHHHHCCCEEEHHHHHHHHHHHHEEEEEEECCCEEEEEEEECCCCCHHHHHHHHCC
DHSRFPYQYPKREVDISHKQFGIDHNRCILCTRCVRVCDEIEGAHVWDVSNRGGESKIVS
CCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHH
GLNQPWGAVDACTSCGKCVDACPTGSIFRKGATVGSKLGDRQKLEFLITARTKGEWTR
CCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHCCCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]