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The map label for this gene is hoxF [H]

Identifier: 170076827

GI number: 170076827

Start: 206812

End: 208416

Strand: Direct

Name: hoxF [H]

Synonym: SYNPCC7002_A0196

Alternate gene names: 170076827

Gene position: 206812-208416 (Clockwise)

Preceding gene: 170076826

Following gene: 170076828

Centisome position: 6.88

GC content: 53.52

Gene sequence:

>1605_bases
ATGACGGATTTAGCGGAATTGTTTGAAATTGCGGAAGCGGAACAGGACAGCCACACAAAAATTCAGATTCGCTGTTGTAC
GGCGGCGGGTTGTATGTCCTCCGGCAGTTTGGCGGTGAAGGAGGAACTGGAAAAACAGATTAAGGAAAAAAATTTGGGTG
ATCGCCTGGAGGTGGTTCCCGTCGGTTGTATGAAACTCTGTGGCTTTGCGCCGTTGGTGGATGTGAGCGATGAGACTTGT
TTCCAGCAGGTGATGCCAGAAGTTGCCCCAGAGATCGTCGATGTAGCATTGGGGGAAACGCCCTCGGATAAGCTGGAAAT
TTGCGATCGCCAAGCGCCATTTTTCACGTTACAAAAACCCGTGGTGCTGGAAAATAGCGGCAAAATTGACCCCGAACGGA
TTGAAGCGTACATTGCGCGGGGCGGCTATCGGTCATTGCACCAAGTGCTCGAAGATCTGACCCCGATGGCGGTGGTGGAA
GAAATTACCCAGAGCGGCCTACGGGGGCGTGGCGGCGGCGGCTATCCCACGGGATTGAAATGGGCGACCGTCGCGAAAAT
GCCGGGGGATCAAAAATATGTCGTCTGTAACGCCGACGAAGGGGATCCGGGGGCATTTATGGATCGGGCGGTGCTCGAAA
GTGACCCCCACCGGGTTCTCGAAGGGATGGCGATCGCCGGCTATGCCGTGGGCGCAAACCACGGATATATTTACATTCGG
GCAGAATATCCCCTCGCGATCCAACGCCTCGAAAAAGCAATCAAACAAGCCAAAAGTAAGGGTTTACTCGGTAGCCAGAT
TTTTAATTCCCCCTTCAATTTCACCATCGACATCCGCATTGGCGCAGGGGCATTCGTTTGTGGCGAAGAAACCGCCCTAA
TTGCCTCCATCGAAGGCGGACGGGGAACCCCCAGACCCAGACCCCCCTACCCCGCCCAGTCCGGACTGTGGGGACATCCC
ACCCTAATCAACAACGTTGAAACCTACGCCAACATCGTCCCGATCATCCGTGAAGGGGCAGACTGGTTTAGCAGCATCGG
CACCGAAAAAAGCAAAGGCACAAAAGTCTTTGCCCTCACCGGAAAAGTGAAAAATAATGGCTTGATCGAAGTGCCGATGG
GAACCCCCGTCCGGCAAATTGTCGAGCAAATGGGCGGTGGCATCCCCGACAGTGGCACAGTCAAATCTGTCCAAACCGGA
GGGCCCTCTGGCGGTTGTATTCCGGCGGACTACCTTGATACGCCCATCGAATATGATTCTTTGATCAAACTCGGCACAAT
GATGGGTTCCGGCGGCATGATCGTTATGGACGAAGCCACTAACATGGTTGATGTGGCGAAGTTTTACATGGAATTTTGCC
AGTGCGAATCCTGCGGTAAATGTATCCCCTGCCGTGCCGGAACGGTGCAGATGTCGGGACTGTTAAGCAAAATGCTCAAG
GGACAGGCTGAACCCAAGGACATTGAACTGCTCGAACAACTTTGTCACATGGTCAAGGAAGCAAGTTTATGTGGGTTAGG
ACAGAGTGCGCCCAATCCAATTTTGAGTACCCTGCGCTATTTCCGCGCGGAATATGATGCCCTCGTGGGGAGTAACGCCG
ATTAA

Upstream 100 bases:

>100_bases
TCAGGTGATGGCAAGGTTGCGGCAGTTGTCTGAAGGAAGTTGACAGGTATCAGGGATCAGAATTTCGGTGTTTGATTTGT
AGTCAGGATTTGCGGGAAAG

Downstream 100 bases:

>100_bases
ATTTTTTTTTAATTCCCATGCAGTCCTTACAGAGAGAACCTTAAGCAAAATCGCAAAACTATGGCAGTTAAAACTTTAAC
GATAAATGATCAGCTAATCA

Product: hydrogenase large diaphorase subunit F

Products: NA

Alternate protein names: NADH dehydrogenase I chain 1; NDH-1 subunit 1 [H]

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MTDLAELFEIAEAEQDSHTKIQIRCCTAAGCMSSGSLAVKEELEKQIKEKNLGDRLEVVPVGCMKLCGFAPLVDVSDETC
FQQVMPEVAPEIVDVALGETPSDKLEICDRQAPFFTLQKPVVLENSGKIDPERIEAYIARGGYRSLHQVLEDLTPMAVVE
EITQSGLRGRGGGGYPTGLKWATVAKMPGDQKYVVCNADEGDPGAFMDRAVLESDPHRVLEGMAIAGYAVGANHGYIYIR
AEYPLAIQRLEKAIKQAKSKGLLGSQIFNSPFNFTIDIRIGAGAFVCGEETALIASIEGGRGTPRPRPPYPAQSGLWGHP
TLINNVETYANIVPIIREGADWFSSIGTEKSKGTKVFALTGKVKNNGLIEVPMGTPVRQIVEQMGGGIPDSGTVKSVQTG
GPSGGCIPADYLDTPIEYDSLIKLGTMMGSGGMIVMDEATNMVDVAKFYMEFCQCESCGKCIPCRAGTVQMSGLLSKMLK
GQAEPKDIELLEQLCHMVKEASLCGLGQSAPNPILSTLRYFRAEYDALVGSNAD

Sequences:

>Translated_534_residues
MTDLAELFEIAEAEQDSHTKIQIRCCTAAGCMSSGSLAVKEELEKQIKEKNLGDRLEVVPVGCMKLCGFAPLVDVSDETC
FQQVMPEVAPEIVDVALGETPSDKLEICDRQAPFFTLQKPVVLENSGKIDPERIEAYIARGGYRSLHQVLEDLTPMAVVE
EITQSGLRGRGGGGYPTGLKWATVAKMPGDQKYVVCNADEGDPGAFMDRAVLESDPHRVLEGMAIAGYAVGANHGYIYIR
AEYPLAIQRLEKAIKQAKSKGLLGSQIFNSPFNFTIDIRIGAGAFVCGEETALIASIEGGRGTPRPRPPYPAQSGLWGHP
TLINNVETYANIVPIIREGADWFSSIGTEKSKGTKVFALTGKVKNNGLIEVPMGTPVRQIVEQMGGGIPDSGTVKSVQTG
GPSGGCIPADYLDTPIEYDSLIKLGTMMGSGGMIVMDEATNMVDVAKFYMEFCQCESCGKCIPCRAGTVQMSGLLSKMLK
GQAEPKDIELLEQLCHMVKEASLCGLGQSAPNPILSTLRYFRAEYDALVGSNAD
>Mature_533_residues
TDLAELFEIAEAEQDSHTKIQIRCCTAAGCMSSGSLAVKEELEKQIKEKNLGDRLEVVPVGCMKLCGFAPLVDVSDETCF
QQVMPEVAPEIVDVALGETPSDKLEICDRQAPFFTLQKPVVLENSGKIDPERIEAYIARGGYRSLHQVLEDLTPMAVVEE
ITQSGLRGRGGGGYPTGLKWATVAKMPGDQKYVVCNADEGDPGAFMDRAVLESDPHRVLEGMAIAGYAVGANHGYIYIRA
EYPLAIQRLEKAIKQAKSKGLLGSQIFNSPFNFTIDIRIGAGAFVCGEETALIASIEGGRGTPRPRPPYPAQSGLWGHPT
LINNVETYANIVPIIREGADWFSSIGTEKSKGTKVFALTGKVKNNGLIEVPMGTPVRQIVEQMGGGIPDSGTVKSVQTGG
PSGGCIPADYLDTPIEYDSLIKLGTMMGSGGMIVMDEATNMVDVAKFYMEFCQCESCGKCIPCRAGTVQMSGLLSKMLKG
QAEPKDIELLEQLCHMVKEASLCGLGQSAPNPILSTLRYFRAEYDALVGSNAD

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is menaquinone. Couples the redox reaction to proton translocation (for every

COG id: COG1894

COG function: function code C; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 51 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI260656005, Length=397, Percent_Identity=39.2947103274559, Blast_Score=305, Evalue=6e-83,
Organism=Homo sapiens, GI20149568, Length=397, Percent_Identity=39.2947103274559, Blast_Score=305, Evalue=6e-83,
Organism=Escherichia coli, GI1788620, Length=413, Percent_Identity=39.9515738498789, Blast_Score=338, Evalue=5e-94,
Organism=Caenorhabditis elegans, GI17531727, Length=397, Percent_Identity=37.7833753148615, Blast_Score=300, Evalue=9e-82,
Organism=Drosophila melanogaster, GI19920794, Length=398, Percent_Identity=38.4422110552764, Blast_Score=299, Evalue=3e-81,
Organism=Drosophila melanogaster, GI45550452, Length=393, Percent_Identity=38.9312977099237, Blast_Score=295, Evalue=8e-80,
Organism=Drosophila melanogaster, GI24653819, Length=422, Percent_Identity=29.3838862559242, Blast_Score=218, Evalue=7e-57,
Organism=Drosophila melanogaster, GI24653817, Length=333, Percent_Identity=29.7297297297297, Blast_Score=184, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001949
- InterPro:   IPR019575
- InterPro:   IPR011537
- InterPro:   IPR011538
- InterPro:   IPR019554 [H]

Pfam domain/function: PF01512 Complex1_51K; PF10589 NADH_4Fe-4S; PF10531 SLBB [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 57410; Mature: 57278

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00645 COMPLEX1_51K_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLAELFEIAEAEQDSHTKIQIRCCTAAGCMSSGSLAVKEELEKQIKEKNLGDRLEVVP
CCCHHHHHHHHHCCCCCCCEEEEEEEEHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEE
VGCMKLCGFAPLVDVSDETCFQQVMPEVAPEIVDVALGETPSDKLEICDRQAPFFTLQKP
HHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEECCC
VVLENSGKIDPERIEAYIARGGYRSLHQVLEDLTPMAVVEEITQSGLRGRGGGGYPTGLK
EEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCC
WATVAKMPGDQKYVVCNADEGDPGAFMDRAVLESDPHRVLEGMAIAGYAVGANHGYIYIR
EEEEECCCCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHCCCCEEEEEECCCCEEEEE
AEYPLAIQRLEKAIKQAKSKGLLGSQIFNSPFNFTIDIRIGAGAFVCGEETALIASIEGG
ECCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEECCCEEEECCCCEEEEEECCC
RGTPRPRPPYPAQSGLWGHPTLINNVETYANIVPIIREGADWFSSIGTEKSKGTKVFALT
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEEEE
GKVKNNGLIEVPMGTPVRQIVEQMGGGIPDSGTVKSVQTGGPSGGCIPADYLDTPIEYDS
EEECCCCEEEECCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHCCCCCCHHH
LIKLGTMMGSGGMIVMDEATNMVDVAKFYMEFCQCESCGKCIPCRAGTVQMSGLLSKMLK
HHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHC
GQAEPKDIELLEQLCHMVKEASLCGLGQSAPNPILSTLRYFRAEYDALVGSNAD
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDLAELFEIAEAEQDSHTKIQIRCCTAAGCMSSGSLAVKEELEKQIKEKNLGDRLEVVP
CCHHHHHHHHHCCCCCCCEEEEEEEEHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEE
VGCMKLCGFAPLVDVSDETCFQQVMPEVAPEIVDVALGETPSDKLEICDRQAPFFTLQKP
HHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEECCC
VVLENSGKIDPERIEAYIARGGYRSLHQVLEDLTPMAVVEEITQSGLRGRGGGGYPTGLK
EEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCC
WATVAKMPGDQKYVVCNADEGDPGAFMDRAVLESDPHRVLEGMAIAGYAVGANHGYIYIR
EEEEECCCCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHCCCCEEEEEECCCCEEEEE
AEYPLAIQRLEKAIKQAKSKGLLGSQIFNSPFNFTIDIRIGAGAFVCGEETALIASIEGG
ECCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEECCCEEEECCCCEEEEEECCC
RGTPRPRPPYPAQSGLWGHPTLINNVETYANIVPIIREGADWFSSIGTEKSKGTKVFALT
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEEEE
GKVKNNGLIEVPMGTPVRQIVEQMGGGIPDSGTVKSVQTGGPSGGCIPADYLDTPIEYDS
EEECCCCEEEECCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHCCCCCCHHH
LIKLGTMMGSGGMIVMDEATNMVDVAKFYMEFCQCESCGKCIPCRAGTVQMSGLLSKMLK
HHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHC
GQAEPKDIELLEQLCHMVKEASLCGLGQSAPNPILSTLRYFRAEYDALVGSNAD
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9020134 [H]