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The map label for this gene is dhaK [H]

Identifier: 170025634

GI number: 170025634

Start: 3751515

End: 3752603

Strand: Reverse

Name: dhaK [H]

Synonym: YPK_3419

Alternate gene names: 170025634

Gene position: 3752603-3751515 (Counterclockwise)

Preceding gene: 170025635

Following gene: 170025633

Centisome position: 80.02

GC content: 49.31

Gene sequence:

>1089_bases
GTGCTGTCGTTGCGCGCGCTAAATTACCGCGGCATCCAGTTAACTCACCCACTGTTTTTATTTATTTTCCATTTTAACGA
GATTGCTATGAATCGAATTATTAACGATCCGGATCAGGTTGTGGAAGAGGCGATAAAAGGCTATTTAGCGGCTTATCCAC
ATTTTTTTGCTAAAACCGCGCATGAGAAAGTATTGAAGTATCCAGAGATACCCCTCCAAGGGAAAGTAGGCGTAGTGACC
GGGGGCGGTTCTGGCCATGAACCCGCGTTTCTGGGCTATATCGGTAAAAATATGCTGGATGCCGTAGCGGTTGGTGAGAT
CTTCTCCTCCCCGGCGGCTGGGGCATTTTTAGAAGCGTTTAAAGTTGCCGACGGCGGTGCGGGTGTTGCTTGTCTGTACG
GTAATTACGCCGGGGACAATATGAACGTCAAAATGGCGGCAAAAAAAGCCGAGGCCATGGGGATAAGGGTTCGCACCGTG
GTTGCTAATGATGATGTGGCCTCTGCACCACCGTCGGAAAGAGAGAAACGCCGAGGTGTGGCGGGGGAAATTTTTATGTG
GAAAGTGGGCGCAGCAGCGGCGTCTCAAGGCTACGCTCTGGATAATGTCATAGAGGTTGCTCAGAAAGCGATTGATCACT
GCCGTTCAATCGGCGTGGGCTTAACCTCCTGTACCATCCCGGCGGTGGGTAAACCTAATTTCTCGATAGAAGACGGCATG
ATGGAAGTGGGGATTGGTCATCACGGAGAACCGGGTATTCGGGTTGAGTCGCTACAGAATGCACATCAGATGGCAAAGAC
CATGGTGGATTTGGTGGTCGCTGATAGGCCGTTTAGCCAAGGCGATGAGGTAGCGGTGTTGATCTCTGGGCTCGGTGCCA
CGCCGACCATTGAGCTGTATATCTATTATGCAGAAGTCGCCAAATTATTAGAGGCGCAGGGGATAACAATATATCGCCCT
TATATTGGTAATTATTTTACCTCGCTAGACATGATGGGGGTCACGCTGACGCTGATGAAACTGGATGATGAATTAAAATC
TTTAATTGATGTACCCACTCATTCATTAGGCTTAACCCAGTTGGAGTAA

Upstream 100 bases:

>100_bases
CCGCCGAAGTTGCAGCGTGCGCACTGTTCTTAGCCAGTGATGCAGCCAATATGATAACCGGTGAAAATTTAGTCATTGAT
GGTGGGTATACCATCCAATA

Downstream 100 bases:

>100_bases
GGGATTATGAAGGCATTGTTGATAACCGATGGATCTATAAAAGATAAGTGCATAACCGACGGTACCCCGATCATTGAAGA
GATGGCCAATACGATCCTCG

Product: Glycerone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MLSLRALNYRGIQLTHPLFLFIFHFNEIAMNRIINDPDQVVEEAIKGYLAAYPHFFAKTAHEKVLKYPEIPLQGKVGVVT
GGGSGHEPAFLGYIGKNMLDAVAVGEIFSSPAAGAFLEAFKVADGGAGVACLYGNYAGDNMNVKMAAKKAEAMGIRVRTV
VANDDVASAPPSEREKRRGVAGEIFMWKVGAAAASQGYALDNVIEVAQKAIDHCRSIGVGLTSCTIPAVGKPNFSIEDGM
MEVGIGHHGEPGIRVESLQNAHQMAKTMVDLVVADRPFSQGDEVAVLISGLGATPTIELYIYYAEVAKLLEAQGITIYRP
YIGNYFTSLDMMGVTLTLMKLDDELKSLIDVPTHSLGLTQLE

Sequences:

>Translated_362_residues
MLSLRALNYRGIQLTHPLFLFIFHFNEIAMNRIINDPDQVVEEAIKGYLAAYPHFFAKTAHEKVLKYPEIPLQGKVGVVT
GGGSGHEPAFLGYIGKNMLDAVAVGEIFSSPAAGAFLEAFKVADGGAGVACLYGNYAGDNMNVKMAAKKAEAMGIRVRTV
VANDDVASAPPSEREKRRGVAGEIFMWKVGAAAASQGYALDNVIEVAQKAIDHCRSIGVGLTSCTIPAVGKPNFSIEDGM
MEVGIGHHGEPGIRVESLQNAHQMAKTMVDLVVADRPFSQGDEVAVLISGLGATPTIELYIYYAEVAKLLEAQGITIYRP
YIGNYFTSLDMMGVTLTLMKLDDELKSLIDVPTHSLGLTQLE
>Mature_362_residues
MLSLRALNYRGIQLTHPLFLFIFHFNEIAMNRIINDPDQVVEEAIKGYLAAYPHFFAKTAHEKVLKYPEIPLQGKVGVVT
GGGSGHEPAFLGYIGKNMLDAVAVGEIFSSPAAGAFLEAFKVADGGAGVACLYGNYAGDNMNVKMAAKKAEAMGIRVRTV
VANDDVASAPPSEREKRRGVAGEIFMWKVGAAAASQGYALDNVIEVAQKAIDHCRSIGVGLTSCTIPAVGKPNFSIEDGM
MEVGIGHHGEPGIRVESLQNAHQMAKTMVDLVVADRPFSQGDEVAVLISGLGATPTIELYIYYAEVAKLLEAQGITIYRP
YIGNYFTSLDMMGVTLTLMKLDDELKSLIDVPTHSLGLTQLE

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=330, Percent_Identity=33.6363636363636, Blast_Score=187, Evalue=1e-47,
Organism=Escherichia coli, GI87081857, Length=355, Percent_Identity=37.7464788732394, Blast_Score=238, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI17565018, Length=326, Percent_Identity=30.9815950920245, Blast_Score=184, Evalue=9e-47,
Organism=Saccharomyces cerevisiae, GI6323570, Length=335, Percent_Identity=32.5373134328358, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6321055, Length=300, Percent_Identity=33, Blast_Score=144, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 38909; Mature: 38909

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLRALNYRGIQLTHPLFLFIFHFNEIAMNRIINDPDQVVEEAIKGYLAAYPHFFAKTA
CCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
HEKVLKYPEIPLQGKVGVVTGGGSGHEPAFLGYIGKNMLDAVAVGEIFSSPAAGAFLEAF
HHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
KVADGGAGVACLYGNYAGDNMNVKMAAKKAEAMGIRVRTVVANDDVASAPPSEREKRRGV
HCCCCCCCEEEEECCCCCCCCEEEEEHHHHHHCCEEEEEEEECCCCCCCCCCHHHHHCCC
AGEIFMWKVGAAAASQGYALDNVIEVAQKAIDHCRSIGVGLTSCTIPAVGKPNFSIEDGM
CCEEEEEEECCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCCCCCCCCCC
MEVGIGHHGEPGIRVESLQNAHQMAKTMVDLVVADRPFSQGDEVAVLISGLGATPTIELY
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEE
IYYAEVAKLLEAQGITIYRPYIGNYFTSLDMMGVTLTLMKLDDELKSLIDVPTHSLGLTQ
EEHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCCCCCCCCC
LE
CC
>Mature Secondary Structure
MLSLRALNYRGIQLTHPLFLFIFHFNEIAMNRIINDPDQVVEEAIKGYLAAYPHFFAKTA
CCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
HEKVLKYPEIPLQGKVGVVTGGGSGHEPAFLGYIGKNMLDAVAVGEIFSSPAAGAFLEAF
HHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
KVADGGAGVACLYGNYAGDNMNVKMAAKKAEAMGIRVRTVVANDDVASAPPSEREKRRGV
HCCCCCCCEEEEECCCCCCCCEEEEEHHHHHHCCEEEEEEEECCCCCCCCCCHHHHHCCC
AGEIFMWKVGAAAASQGYALDNVIEVAQKAIDHCRSIGVGLTSCTIPAVGKPNFSIEDGM
CCEEEEEEECCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCCCCCCCCCC
MEVGIGHHGEPGIRVESLQNAHQMAKTMVDLVVADRPFSQGDEVAVLISGLGATPTIELY
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEE
IYYAEVAKLLEAQGITIYRPYIGNYFTSLDMMGVTLTLMKLDDELKSLIDVPTHSLGLTQ
EEHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCCCCCCCCC
LE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]