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The map label for this gene is espR [H]

Identifier: 169630466

GI number: 169630466

Start: 3434589

End: 3435335

Strand: Direct

Name: espR [H]

Synonym: MAB_3385

Alternate gene names: 169630466

Gene position: 3434589-3435335 (Clockwise)

Preceding gene: 169630460

Following gene: 169630468

Centisome position: 67.78

GC content: 58.63

Gene sequence:

>747_bases
ATGACAAACGACTTCGATCCGGATCCTTACCTGGAGACGGTGCAGAGCATCGGGCTTGCTAACCATCGGCTCATCGCGCA
GCTCGATGCGGAGGCATCTCAGATTCAGCAACGTGCCGCTGACGGCGAAGATCGATCGTGGATATGGGATGACCTCAAGG
TGTGGCGTCGCCGAGTTGATGCTTTTCAATCGCAGCTGCGTCGCGACACCACCGCGCTGGGCCGCCTGATCGACGCTAAT
CGGCGAATCAAAGGATCGGATCAGACTGCCGATATCGGCACATCAAAACTTGATTATTCGCCCGACAGCAACCGCAATAC
GCTCCATCCCTTCAAGGACTCGCGATCTCAGGAGGAATTCGTCTCCAGACTTAACCGAGTGTTCGCGGTCCTACACTCAC
CTGGGCGCGGCCCGTACTCAAATAGCGAATTTCTTGTCTTCATGCGAACGGGCGGCACCGTCGTCTCGGCACCTTATCTG
TCGCAGTTGCGCAACGGGCAGCGAGGCCGGCCCTCACTGCAGGCGTTGGAGAGCATCGCGCATGCCTTTCGCATCGATGT
CCGTTACTTCATCGATAGTGGCTACGCCGATGAGCTGGAGTCAGATCTGAGTGCGCTCGAACTCGCCCACAACCCGGCGG
CGGCCGAGCTGACATCCAAACTGCTCGAACTGCCTGAGCCCGTTCGCGACCAGTTACTCGCCGATGCGGAGTCCTTCGAT
CGCCGCAATCAGACCGCGACATCCTGA

Upstream 100 bases:

>100_bases
CGGGAGCCCTATAGCGCGTCATCTCCGACATGCGCCCAGACCTGTATCGCGTATCCTCACTCATACGTTAGCAATCTCGG
AGGGAATTCCAGGCAACCAC

Downstream 100 bases:

>100_bases
GCTGAATCCAGCGGAGTGGACCGTGATTCGGCGTTGCGCTGCGTACTGAGCACCGGGCCCCAGCCACTGACGGCCAAGAG
CCGCCGCGGCACCAGTCGCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTNDFDPDPYLETVQSIGLANHRLIAQLDAEASQIQQRAADGEDRSWIWDDLKVWRRRVDAFQSQLRRDTTALGRLIDAN
RRIKGSDQTADIGTSKLDYSPDSNRNTLHPFKDSRSQEEFVSRLNRVFAVLHSPGRGPYSNSEFLVFMRTGGTVVSAPYL
SQLRNGQRGRPSLQALESIAHAFRIDVRYFIDSGYADELESDLSALELAHNPAAAELTSKLLELPEPVRDQLLADAESFD
RRNQTATS

Sequences:

>Translated_248_residues
MTNDFDPDPYLETVQSIGLANHRLIAQLDAEASQIQQRAADGEDRSWIWDDLKVWRRRVDAFQSQLRRDTTALGRLIDAN
RRIKGSDQTADIGTSKLDYSPDSNRNTLHPFKDSRSQEEFVSRLNRVFAVLHSPGRGPYSNSEFLVFMRTGGTVVSAPYL
SQLRNGQRGRPSLQALESIAHAFRIDVRYFIDSGYADELESDLSALELAHNPAAAELTSKLLELPEPVRDQLLADAESFD
RRNQTATS
>Mature_247_residues
TNDFDPDPYLETVQSIGLANHRLIAQLDAEASQIQQRAADGEDRSWIWDDLKVWRRRVDAFQSQLRRDTTALGRLIDANR
RIKGSDQTADIGTSKLDYSPDSNRNTLHPFKDSRSQEEFVSRLNRVFAVLHSPGRGPYSNSEFLVFMRTGGTVVSAPYLS
QLRNGQRGRPSLQALESIAHAFRIDVRYFIDSGYADELESDLSALELAHNPAAAELTSKLLELPEPVRDQLLADAESFDR
RNQTATS

Specific function: Required for secretion and virulence in mice. Activates transcription of an operon that includes espA, espC and espD genes, which are ESX-1 components. Acts by binding directly to the promoter region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Note=Probably secreted via the ESX-1 / type VII secretion system (T7SS) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 27950; Mature: 27819

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNDFDPDPYLETVQSIGLANHRLIAQLDAEASQIQQRAADGEDRSWIWDDLKVWRRRVD
CCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
AFQSQLRRDTTALGRLIDANRRIKGSDQTADIGTSKLDYSPDSNRNTLHPFKDSRSQEEF
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
VSRLNRVFAVLHSPGRGPYSNSEFLVFMRTGGTVVSAPYLSQLRNGQRGRPSLQALESIA
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEECHHHHHHHCCCCCCHHHHHHHHHH
HAFRIDVRYFIDSGYADELESDLSALELAHNPAAAELTSKLLELPEPVRDQLLADAESFD
HHHHHHHHHEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RRNQTATS
HCCCCCCC
>Mature Secondary Structure 
TNDFDPDPYLETVQSIGLANHRLIAQLDAEASQIQQRAADGEDRSWIWDDLKVWRRRVD
CCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
AFQSQLRRDTTALGRLIDANRRIKGSDQTADIGTSKLDYSPDSNRNTLHPFKDSRSQEEF
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
VSRLNRVFAVLHSPGRGPYSNSEFLVFMRTGGTVVSAPYLSQLRNGQRGRPSLQALESIA
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEECHHHHHHHCCCCCCHHHHHHHHHH
HAFRIDVRYFIDSGYADELESDLSALELAHNPAAAELTSKLLELPEPVRDQLLADAESFD
HHHHHHHHHEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RRNQTATS
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]