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The map label for this gene is hup [H]

Identifier: 169630373

GI number: 169630373

Start: 3331283

End: 3331906

Strand: Reverse

Name: hup [H]

Synonym: MAB_3292c

Alternate gene names: 169630373

Gene position: 3331906-3331283 (Counterclockwise)

Preceding gene: 169630374

Following gene: 169630369

Centisome position: 65.75

GC content: 66.03

Gene sequence:

>624_bases
ATGAACAAAGCAGAGCTCATCGACGTTCTGACACAGAAGTTGGGCTCGGATCGCCGGCAGGCCACCGCTGCGGTGGAGCA
CGTCGTCGACACCATCGTTCGCACCGTGCACAAGGGTGAGAGCGTGACCATCACCGGATTTGGCGTTTTCGAGCAGCGTC
GCCGCGCCGCTCGTGTCGCCCGCAACCCGCGTACCGGTGAGACCGTCAAGGTGAAGCCGACGTCGGTGCCGACGTTCCGT
CCCGGTGCGCAGTTCAAGGCGGTTGTCTCTGGTGCGCAGAAGCTTCCGGCCGACGGCCCCGCTGTGAAGCGTGGCTCCAC
CGCCGCCCCGGCCAAGCGCGCCGCTGCCAAGAAGGCCGCCCCGGCCAAGAAGGCTCCCGCCAAGAAGGCCGCGCCTGCCA
AGAAGGCTCCGGTCAAGAAGGCAGTCGTCAAGAAGGCTGCTCCTGTCAAGAAGGCTCCGGTCAAGAAGGCAGTCGTCAAG
AAGGCTGCTCCGGTCAAGAAGGCCGTGACCAAGGCTCCCGCCAAGAAGGCCGCGACCAAGGCTCCGGCCAAGAAGGCCGC
GACCAAGGCTCCCGCCAAGAAGGCCCCGGCCAAGAAGGCTCCGGCCAAGAAGGGCCGCAAGTAG

Upstream 100 bases:

>100_bases
TTTTGCCGAAAATACGCGTGGCACTTGGAAATCACGTGCAGTTGGGTTTACCGTGTTCGAAGTCGGTTCAAAGTGGACCA
CTGGCTTCGGAGGGTTTTAC

Downstream 100 bases:

>100_bases
TTTCCCGACAACATCGGGTCCCACCTCAGGGTGGGGCCCGATGTTGCTTTTTTGGGGGTCTCCGTCAGCTGCCCGCCGGC
AGCGGGCTGTCCAGATGGTC

Product: DNA-binding protein HU

Products: NA

Alternate protein names: Histone-like protein; Hlp [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MNKAELIDVLTQKLGSDRRQATAAVEHVVDTIVRTVHKGESVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPTFR
PGAQFKAVVSGAQKLPADGPAVKRGSTAAPAKRAAAKKAAPAKKAPAKKAAPAKKAPVKKAVVKKAAPVKKAPVKKAVVK
KAAPVKKAVTKAPAKKAATKAPAKKAATKAPAKKAPAKKAPAKKGRK

Sequences:

>Translated_207_residues
MNKAELIDVLTQKLGSDRRQATAAVEHVVDTIVRTVHKGESVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPTFR
PGAQFKAVVSGAQKLPADGPAVKRGSTAAPAKRAAAKKAAPAKKAPAKKAAPAKKAPVKKAVVKKAAPVKKAPVKKAVVK
KAAPVKKAVTKAPAKKAATKAPAKKAATKAPAKKAPAKKAPAKKGRK
>Mature_207_residues
MNKAELIDVLTQKLGSDRRQATAAVEHVVDTIVRTVHKGESVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPTFR
PGAQFKAVVSGAQKLPADGPAVKRGSTAAPAKRAAAKKAAPAKKAPAKKAAPAKKAPVKKAVVKKAAPVKKAPVKKAVVK
KAAPVKKAVTKAPAKKAATKAPAKKAATKAPAKKAPAKKAPAKKGRK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1788005, Length=92, Percent_Identity=40.2173913043478, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790433, Length=82, Percent_Identity=40.2439024390244, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1786644, Length=92, Percent_Identity=35.8695652173913, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 21450; Mature: 21450

Theoretical pI: Translated: 12.23; Mature: 12.23

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKAELIDVLTQKLGSDRRQATAAVEHVVDTIVRTVHKGESVTITGFGVFEQRRRAARVA
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHH
RNPRTGETVKVKPTSVPTFRPGAQFKAVVSGAQKLPADGPAVKRGSTAAPAKRAAAKKAA
CCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCC
PAKKAPAKKAAPAKKAPVKKAVVKKAAPVKKAPVKKAVVKKAAPVKKAVTKAPAKKAATK
CCCCCCCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APAKKAATKAPAKKAPAKKAPAKKGRK
CHHHHHHHHCCHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MNKAELIDVLTQKLGSDRRQATAAVEHVVDTIVRTVHKGESVTITGFGVFEQRRRAARVA
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHH
RNPRTGETVKVKPTSVPTFRPGAQFKAVVSGAQKLPADGPAVKRGSTAAPAKRAAAKKAA
CCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCC
PAKKAPAKKAAPAKKAPVKKAVVKKAAPVKKAPVKKAVVKKAAPVKKAVTKAPAKKAATK
CCCCCCCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APAKKAATKAPAKKAPAKKAPAKKGRK
CHHHHHHHHCCHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9894918 [H]