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The map label for this gene is thiL [H]

Identifier: 169630365

GI number: 169630365

Start: 3322532

End: 3323479

Strand: Reverse

Name: thiL [H]

Synonym: MAB_3284c

Alternate gene names: 169630365

Gene position: 3323479-3322532 (Counterclockwise)

Preceding gene: 169630367

Following gene: 169630364

Centisome position: 65.59

GC content: 66.46

Gene sequence:

>948_bases
GTGCCAAATCTGGGCGATACCGGCGAGTTCGGTGTGATCAGCCGTCTCACCGCGGGCCGTGATCTGGGCGCCGACGTGCT
GCTCGGCCCCGGTGACGACGCCGCGGTGGTCACCGTGCCGGACGGCCGTGTGGTGGTATCCACCGATATGTTGGTGCAGG
ACAGGCATTTTCGTCTTGAATGGTCATCGCCGTCGGATATCGGCCGAAAAGCGGTAGCACAGAATGCCGCGGATATAGAA
GCAATGGGCGGACGGGTCACGGCCTTCGTGGTGGCGGTGGGCGCTCCGGCGCAGACCGATATCGCGTTCCTCGACCAGCT
CAACGAGGGAGTCTGGGCGGAGGCGGCCCTGGTACAGGCACCGATCGTGGGCGGCGATCTGGTGAGCGCGCGCGAACTGG
TGGTTTCGGTCACGGTGCTCGGCGACCTCCAGGGGCGCGCACCGGTGACCCGTAGTGGAGCGGTGGTAGGGGATACCGTC
GCGATCTGTGGTGCGTTGGGCACCTCTGCGGCGGGATACCGGTTGTGGCAGGAACAGATTGACGAGTTCCCAGATCTGCG
GCGGGTGCATCTGGTGCCCGCGCCGCCGTATGGCCAGGGTCCGGCCGCAGCACGGGCGGGTGCGACGGCGATGACAGACG
TCTCCGACGGTCTGCTGGCCGATCTGGCGCATATCGCCGAACTCAGCGCGGTGCACATCGACCTGAGTTCGCCGAGCCTG
GAACCATATCTACAGCCTGTGGCGGGCGCTGCCGGTCTGCTCGGCGCCGACCCCTGGGAATGGGTCTTGACCGGTGGTGA
GGATCATGCGCTGGTCGGGATGTTCCCCGGAGTCGTCCCGACGGGCTGGGTTCCGATCGGCCGGGTAACGGTGGGGGAAC
CCGGAGTGACGGTTGACGGGGCAGCATGGACTCGGGCAACCGGTTGGGACTCGTTTCGGCTAAGTTGA

Upstream 100 bases:

>100_bases
AAAAGCACCGCCAGCGCCGCGATCGCGCCGAACACCGCGATGCCGATGAGTAGCTTGCGTGGTGGGCCGTCTTCGGATTG
CACGGGCCTACACTAACCGA

Downstream 100 bases:

>100_bases
CTCTTCGTGACTGCCCGACCTCTTGCCGAGTTGGTTGACCCCGGCTGGGCCGATGCGCTGGGGCCCGTCGCCGACCAGGT
GACCAAGATGGGAGAGTTCC

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MPNLGDTGEFGVISRLTAGRDLGADVLLGPGDDAAVVTVPDGRVVVSTDMLVQDRHFRLEWSSPSDIGRKAVAQNAADIE
AMGGRVTAFVVAVGAPAQTDIAFLDQLNEGVWAEAALVQAPIVGGDLVSARELVVSVTVLGDLQGRAPVTRSGAVVGDTV
AICGALGTSAAGYRLWQEQIDEFPDLRRVHLVPAPPYGQGPAAARAGATAMTDVSDGLLADLAHIAELSAVHIDLSSPSL
EPYLQPVAGAAGLLGADPWEWVLTGGEDHALVGMFPGVVPTGWVPIGRVTVGEPGVTVDGAAWTRATGWDSFRLS

Sequences:

>Translated_315_residues
MPNLGDTGEFGVISRLTAGRDLGADVLLGPGDDAAVVTVPDGRVVVSTDMLVQDRHFRLEWSSPSDIGRKAVAQNAADIE
AMGGRVTAFVVAVGAPAQTDIAFLDQLNEGVWAEAALVQAPIVGGDLVSARELVVSVTVLGDLQGRAPVTRSGAVVGDTV
AICGALGTSAAGYRLWQEQIDEFPDLRRVHLVPAPPYGQGPAAARAGATAMTDVSDGLLADLAHIAELSAVHIDLSSPSL
EPYLQPVAGAAGLLGADPWEWVLTGGEDHALVGMFPGVVPTGWVPIGRVTVGEPGVTVDGAAWTRATGWDSFRLS
>Mature_314_residues
PNLGDTGEFGVISRLTAGRDLGADVLLGPGDDAAVVTVPDGRVVVSTDMLVQDRHFRLEWSSPSDIGRKAVAQNAADIEA
MGGRVTAFVVAVGAPAQTDIAFLDQLNEGVWAEAALVQAPIVGGDLVSARELVVSVTVLGDLQGRAPVTRSGAVVGDTVA
ICGALGTSAAGYRLWQEQIDEFPDLRRVHLVPAPPYGQGPAAARAGATAMTDVSDGLLADLAHIAELSAVHIDLSSPSLE
PYLQPVAGAAGLLGADPWEWVLTGGEDHALVGMFPGVVPTGWVPIGRVTVGEPGVTVDGAAWTRATGWDSFRLS

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=334, Percent_Identity=31.1377245508982, Blast_Score=108, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 32435; Mature: 32304

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNLGDTGEFGVISRLTAGRDLGADVLLGPGDDAAVVTVPDGRVVVSTDMLVQDRHFRLE
CCCCCCCCCCCHHHHHHCCCCCCCCEEEECCCCEEEEEECCCCEEEEECEEEECCEEEEE
WSSPSDIGRKAVAQNAADIEAMGGRVTAFVVAVGAPAQTDIAFLDQLNEGVWAEAALVQA
ECCCHHHHHHHHHCCCCHHHHCCCEEEEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHCC
PIVGGDLVSARELVVSVTVLGDLQGRAPVTRSGAVVGDTVAICGALGTSAAGYRLWQEQI
CCCCCCHHHHHHEEEEEEEEECCCCCCCCCCCCCEECHHHHHHHHHCCCHHHHHHHHHHH
DEFPDLRRVHLVPAPPYGQGPAAARAGATAMTDVSDGLLADLAHIAELSAVHIDLSSPSL
HCCCCCEEEEEEECCCCCCCCCHHHCCCCEEHHCCCHHHHHHHHHHHEEEEEEECCCCCC
EPYLQPVAGAAGLLGADPWEWVLTGGEDHALVGMFPGVVPTGWVPIGRVTVGEPGVTVDG
CHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCEEECEEEECCCCCEECC
AAWTRATGWDSFRLS
CCEEECCCCCCEECC
>Mature Secondary Structure 
PNLGDTGEFGVISRLTAGRDLGADVLLGPGDDAAVVTVPDGRVVVSTDMLVQDRHFRLE
CCCCCCCCCCHHHHHHCCCCCCCCEEEECCCCEEEEEECCCCEEEEECEEEECCEEEEE
WSSPSDIGRKAVAQNAADIEAMGGRVTAFVVAVGAPAQTDIAFLDQLNEGVWAEAALVQA
ECCCHHHHHHHHHCCCCHHHHCCCEEEEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHCC
PIVGGDLVSARELVVSVTVLGDLQGRAPVTRSGAVVGDTVAICGALGTSAAGYRLWQEQI
CCCCCCHHHHHHEEEEEEEEECCCCCCCCCCCCCEECHHHHHHHHHCCCHHHHHHHHHHH
DEFPDLRRVHLVPAPPYGQGPAAARAGATAMTDVSDGLLADLAHIAELSAVHIDLSSPSL
HCCCCCEEEEEEECCCCCCCCCHHHCCCCEEHHCCCHHHHHHHHHHHEEEEEEECCCCCC
EPYLQPVAGAAGLLGADPWEWVLTGGEDHALVGMFPGVVPTGWVPIGRVTVGEPGVTVDG
CHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCEEECEEEECCCCCEECC
AAWTRATGWDSFRLS
CCEEECCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377; 8419296 [H]