Click here to switch to the map view.

The map label for this gene is pyrH [H]

Identifier: 169630270

GI number: 169630270

Start: 3232315

End: 3233040

Strand: Reverse

Name: pyrH [H]

Synonym: MAB_3188c

Alternate gene names: 169630270

Gene position: 3233040-3232315 (Counterclockwise)

Preceding gene: 169630271

Following gene: 169630269

Centisome position: 63.8

GC content: 63.64

Gene sequence:

>726_bases
ATGACGCGCGATGTGAGCCGCACCGGATATAAGCGGGTGCTGCTCAAGCTCGGCGGCGAAATGTTCGGTGGGGGTGCCGT
CGGCTTGGACCCTGATGTGGTTCACCGGGTGGCCAGGCAGATTGCCGAGGTGGTACGTACCGGTGCCGAGGTTGCGGTGG
TGATCGGCGGCGGCAACTTCTTCCGGGGCGCCCAGTTGCAGCAGCGCGGTATGGAGCGCACTCGGTCGGACTACATGGGC
ATGCTCGGAACCGTGATGAACAGCCTTGCGCTGCAAGACTTCCTGGAAAAGGAAGGCATCGTGACGCGCGTGCAGACCGC
CATCACCATGGGGCAGGTCGCCGAGCCGTACATTCCGCTGCGTGCCAGAAGGCACTTGGAGAAGGGGCGTGTCGTCATCT
TCGGTGCCGGCATGGGCCTGCCGTACTTCTCCACCGACACTACGGCCGCGCAGCGTGCACTGGAGATTGGCGCCGAGGTG
GTGCTGATGGCCAAGGCGGTTGACGGCATCTTCACCGACGACCCGCGCGCCAATCCCGACGCCGAATTCCTGCCCGAGAT
CACGCACCGCGAGGTCATCGATCGCGGCCTACAGGTCGCCGATGCCACCGCGTTCAGCCTGTGTATGGACAACCGGATGC
CGATCCTGGTGTTCAACCTGCTTACCGAAGGGAATATCGCAAGGGCGGTCGCAGGTGAGAAGATCGGAACGCTGGTAACA
CCGTGA

Upstream 100 bases:

>100_bases
GTCCGCGAGATAGATGCAGCCGTCGAGGCGCCCGGGGTATCCGGGGCCCGATGGCTGTGCTTGTGCACCGGCTTTGTTGA
GCCCGTACCGAGGAGGCGTG

Downstream 100 bases:

>100_bases
TGAGGCCCCCGCAGGCGGGCGGTGGCCCCAGCTTGCGCGAAGATCATCGAACCCGATGGGAGATCAATCGTGATTGACGA
GGTTCTTCTCGATGCCGAGG

Product: uridylate kinase PyrH

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MTRDVSRTGYKRVLLKLGGEMFGGGAVGLDPDVVHRVARQIAEVVRTGAEVAVVIGGGNFFRGAQLQQRGMERTRSDYMG
MLGTVMNSLALQDFLEKEGIVTRVQTAITMGQVAEPYIPLRARRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGAEV
VLMAKAVDGIFTDDPRANPDAEFLPEITHREVIDRGLQVADATAFSLCMDNRMPILVFNLLTEGNIARAVAGEKIGTLVT
P

Sequences:

>Translated_241_residues
MTRDVSRTGYKRVLLKLGGEMFGGGAVGLDPDVVHRVARQIAEVVRTGAEVAVVIGGGNFFRGAQLQQRGMERTRSDYMG
MLGTVMNSLALQDFLEKEGIVTRVQTAITMGQVAEPYIPLRARRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGAEV
VLMAKAVDGIFTDDPRANPDAEFLPEITHREVIDRGLQVADATAFSLCMDNRMPILVFNLLTEGNIARAVAGEKIGTLVT
P
>Mature_240_residues
TRDVSRTGYKRVLLKLGGEMFGGGAVGLDPDVVHRVARQIAEVVRTGAEVAVVIGGGNFFRGAQLQQRGMERTRSDYMGM
LGTVMNSLALQDFLEKEGIVTRVQTAITMGQVAEPYIPLRARRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGAEVV
LMAKAVDGIFTDDPRANPDAEFLPEITHREVIDRGLQVADATAFSLCMDNRMPILVFNLLTEGNIARAVAGEKIGTLVTP

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=232, Percent_Identity=46.551724137931, Blast_Score=205, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26092; Mature: 25960

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRDVSRTGYKRVLLKLGGEMFGGGAVGLDPDVVHRVARQIAEVVRTGAEVAVVIGGGNF
CCCCCCHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
FRGAQLQQRGMERTRSDYMGMLGTVMNSLALQDFLEKEGIVTRVQTAITMGQVAEPYIPL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCH
RARRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGAEVVLMAKAVDGIFTDDPRANPD
HHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AEFLPEITHREVIDRGLQVADATAFSLCMDNRMPILVFNLLTEGNIARAVAGEKIGTLVT
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCCCCCCCC
P
C
>Mature Secondary Structure 
TRDVSRTGYKRVLLKLGGEMFGGGAVGLDPDVVHRVARQIAEVVRTGAEVAVVIGGGNF
CCCCCHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
FRGAQLQQRGMERTRSDYMGMLGTVMNSLALQDFLEKEGIVTRVQTAITMGQVAEPYIPL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCH
RARRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGAEVVLMAKAVDGIFTDDPRANPD
HHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AEFLPEITHREVIDRGLQVADATAFSLCMDNRMPILVFNLLTEGNIARAVAGEKIGTLVT
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCCCCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA