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The map label for this gene is frr

Identifier: 169630269

GI number: 169630269

Start: 3231688

End: 3232245

Strand: Reverse

Name: frr

Synonym: MAB_3187c

Alternate gene names: 169630269

Gene position: 3232245-3231688 (Counterclockwise)

Preceding gene: 169630270

Following gene: 169630268

Centisome position: 63.79

GC content: 61.29

Gene sequence:

>558_bases
GTGATTGACGAGGTTCTTCTCGATGCCGAGGAGAAGATGGAAAAGGCCGTGACGGTCGCCCGCGACGACTTCGCGACCAT
TCGGACCGGGCGGGCAAACCCCGGCATGTTCCAGCGGGTCGTCATCGACTACTACGGCACTCCGACCCCGATCACGCAGG
TGGCCGGTATCAACGTGCCCGAGGCGCGCATGGTGGTCATCAAGCCCTATGAGTCCAACCAGCTCAAGGCCATCGAAGAC
GCGATCCGCAACTCGGATCTGGGCTTGAACCCGAGCAATGATGGCAGCATCATTCGTGTCGCCATTCCTCAGCTCACCGA
GGAGCGCCGCCGCGAGCTGGTCAAGCAGGCCAAGGGCAAGGGCGAGGACGCCAAGGTGACCCTGCGCAATATCCGGCGTA
AGGCCAACGACGAGCTTAACCGGATCAAGAAAGATGGCGAGGCCGGCGAGGACGAGGTGGGCCGAGCGGAAAAGGATCTG
GACAAGACCACCGCGCAGTACGTGAGCCAGATCGATGAGCTGGTGAAACACAAAGAAGGCGAGCTACTGGAGGTCTAG

Upstream 100 bases:

>100_bases
TGAGAAGATCGGAACGCTGGTAACACCGTGATGAGGCCCCCGCAGGCGGGCGGTGGCCCCAGCTTGCGCGAAGATCATCG
AACCCGATGGGAGATCAATC

Downstream 100 bases:

>100_bases
GGCCGCCGGTAGTGACGACCATGGGAGACACCGACGCGGCTCCGGCCCCCGGCAGCAGCCCTGCGCCCCCTGCGGGGGCG
AAGTCCCGGGCCGGGCGCAA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIDEVLLDAEEKMEKAVTVARDDFATIRTGRANPGMFQRVVIDYYGTPTPITQVAGINVPEARMVVIKPYESNQLKAIED
AIRNSDLGLNPSNDGSIIRVAIPQLTEERRRELVKQAKGKGEDAKVTLRNIRRKANDELNRIKKDGEAGEDEVGRAEKDL
DKTTAQYVSQIDELVKHKEGELLEV

Sequences:

>Translated_185_residues
MIDEVLLDAEEKMEKAVTVARDDFATIRTGRANPGMFQRVVIDYYGTPTPITQVAGINVPEARMVVIKPYESNQLKAIED
AIRNSDLGLNPSNDGSIIRVAIPQLTEERRRELVKQAKGKGEDAKVTLRNIRRKANDELNRIKKDGEAGEDEVGRAEKDL
DKTTAQYVSQIDELVKHKEGELLEV
>Mature_185_residues
MIDEVLLDAEEKMEKAVTVARDDFATIRTGRANPGMFQRVVIDYYGTPTPITQVAGINVPEARMVVIKPYESNQLKAIED
AIRNSDLGLNPSNDGSIIRVAIPQLTEERRRELVKQAKGKGEDAKVTLRNIRRKANDELNRIKKDGEAGEDEVGRAEKDL
DKTTAQYVSQIDELVKHKEGELLEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=181, Percent_Identity=29.8342541436464, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI291042689, Length=136, Percent_Identity=33.8235294117647, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=42.3913043478261, Blast_Score=157, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24661488, Length=176, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_MYCA9 (B1MDE3)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001703918.1
- ProteinModelPortal:   B1MDE3
- SMR:   B1MDE3
- EnsemblBacteria:   EBMYCT00000007370
- GeneID:   5965692
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_3187c
- GeneTree:   EBGT00050000017615
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   MABS561007:MAB_3187C-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20715; Mature: 20715

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDEVLLDAEEKMEKAVTVARDDFATIRTGRANPGMFQRVVIDYYGTPTPITQVAGINVP
CCCHHHHCHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHCCCCCC
EARMVVIKPYESNQLKAIEDAIRNSDLGLNPSNDGSIIRVAIPQLTEERRRELVKQAKGK
CCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCC
GEDAKVTLRNIRRKANDELNRIKKDGEAGEDEVGRAEKDLDKTTAQYVSQIDELVKHKEG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ELLEV
CEECC
>Mature Secondary Structure
MIDEVLLDAEEKMEKAVTVARDDFATIRTGRANPGMFQRVVIDYYGTPTPITQVAGINVP
CCCHHHHCHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHCCCCCC
EARMVVIKPYESNQLKAIEDAIRNSDLGLNPSNDGSIIRVAIPQLTEERRRELVKQAKGK
CCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCC
GEDAKVTLRNIRRKANDELNRIKKDGEAGEDEVGRAEKDLDKTTAQYVSQIDELVKHKEG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ELLEV
CEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA