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The map label for this gene is helD [H]

Identifier: 169630271

GI number: 169630271

Start: 3233150

End: 3235411

Strand: Reverse

Name: helD [H]

Synonym: MAB_3189c

Alternate gene names: 169630271

Gene position: 3235411-3233150 (Counterclockwise)

Preceding gene: 169630272

Following gene: 169630270

Centisome position: 63.85

GC content: 66.71

Gene sequence:

>2262_bases
ATGGGGAAATTTCGGTTGACGACGCACGAAGAAGAACTGCAGGCCGAGCGCGAATACATCGCTGGACTGTATGAGCGGCT
CGATGCCGAACGCGCGCGTGTGAAGGGGCGATACCGCAGCGCCCTGCGCGGGCCTGTCGACCAGCAGAACGGTGGGGCGA
TGGCGGAGCGCGACGACGAGGTGCGCGCACTGGCCAGGCAGGCGCAGCGCCTGGATGTCGCCGATGACGGGCTGTGCTTC
GGCCGGCTGGACGCCATCACCGGCGAGCGCTCCTACGTCGGGCGCATCGGCCTCCTCGATGAGAGCAACGACTACGAACC
GCTGCTGATCGATTGGCGGGCGCCCGCGGCGCAAGCGTTTTATATCGCGACCAGCGCGCATCCCGAGAACACCCGGCGCC
GGCGCCAGTTCCGCACACGGGGACGTCACGTCGACGACTTCACCGATGAGATCCTCGGCCGCCCGGATGGCGAGGACCAC
GACGGGGAACGCGGAACTCTGAGTGATGCCGCGCTGCTGGCCGCGGTGAACGCGCCGCGTGGTCACGGGATGCGCGACAT
CGTGGCAACCATCCAGGCCGAACAGGACCGGATCATCCGACTCGACCATCCGGGCGTACTGGTGATCGAGGGCGGTCCCG
GCACGGGCAAAACGGTGGTGGCGCTGCACCGGGTGGCGTATCTGCTGTACACCCAGCGCAAACGGATGGAACGCCACGGG
GTGCTGGTCGTTGGCCCGAATGCGGCCTTCCTGGGCCATATCTCTCGCGTGCTGCCCTCGCTGGGGGAGACGAACGTGGT
GTTTACCACGGCGGGTGATCTGGTACCGGGCCTCAAGGTCACCGCGGAGGACGACGAGGAGGCCGCCCGGGTCAAGGGCT
CGCTGCAGATTCTGGATGTGCTGGCCGCCGCCGTCGCGGATCGGCAGCGGGCGCCCGAGAATCCGATGCCGATTCAGCTT
GCCGACGTCAGCGTGCGCATCGATGCCGACATTGCGCAGTGGGCCATTGAGGAGGCCCGCGCGAGCAAGCTTCCGCACAA
CGAGGCCAGGACGGTATTTACCGACGTGCTCACCTGGGCGCTGACCGAGCGGGCCATCCCGCGCATCGGCAAGGGATGGC
TGACTCGCGAGGACCGCAAGGCCTGGGAACACCTGCGCGCCGAGCTTCTCGACGAACTGGGGGATCACGAGGGATTCGCC
GCTGCCCTGGACGCGCTGTGGCCGATGCTCACACCGGAGACACTGTTGTCGGAGTTGTACACCTCGCCCGAGCGATTGCG
GGCGGCCGGCGCGGATCCAGCGCTGGCCCGGCGCATAGGTGATGCGTGGACAGTCTCCGATGTTCCCTTGCTGGACGAGC
TGGTCGATCTGCTGGGCCGTGACAAGGCGGCAGAAGAAGCCGCCGAACGTGAACGCAGGGCCGAGGCCGAGTATGCCGCC
GGTGTCCTCGATCTGATGACCGGTCGCGAGGACATGATGGACGACGAGGACCACCTCTTCGCCACCGATCTGTTGGGGGC
GGAGGATCTCGCGGAACGATTCACCGAACGTGACACTCGCGACCTGGTCGAACGTGCGTCGGCCGACAGAGACTGGACCT
ATGGACACATTGTGATCGATGAGGCGCAGGAGCTGTCCGAGATGGACTGGCGAGTGTTGATGCGCCGCTGCCCAAGTCGT
TCGTTCACGGTCGTGGGCGATCTGGCTCAGCGCCGATCAGCCGCCGGTGCCACATCCTGGGAGGCGATGCTGCAGCCGTA
CGTGCCCGGGCGCTGGCTGTACCGGCCGCTGTCGGTCAACTACCGCACGCCCGCAGAAATCATGGCCGTTGCTTCGGCGG
TGCTGGCCGAGTTCGCGCCGGGTACCCAACCGCCCGAATCCGTCCGTTCAAGCGGCGTCCTGCCGTGGTCCAGGCGCCTC
TCCGAAGGCGAATTGCCAAAAGCCATAGAAGAATTCGTGCTGAACGAGAAAGGTCGCGAGGGTACCAGTGTGGTGATCGG
CCCACCGGGTGTGCCGGGCACAGTGCCGGCCTCGGAGACCAAGGGGCTCGAGTTCGACGCGGTGCTGGTGGTGGAACCGG
AACGTATCCTGGCCGACGGTCCGCGTGGCGCCGCTGAACTCTATGTGGCGCTCACCCGTGCCACGCAGCGGTTGGGGGTG
CTGCATGTGGCGCCGCTGCCTCAGCCCCTGATCGGTCTGACCGAAAGCACAACCGGCCCAGGCCCGGATCACCGGGTCAT
GCCAACAGGCGTCGCCCAATAG

Upstream 100 bases:

>100_bases
CCCTTTCAACTTATAACGCACAGGGGGGCTTGCGGCAAGACCCGGGTGATACCGCACAATCACTGAGCTCAAATGTCAGA
TGCCATGGACTACAAGGAAA

Downstream 100 bases:

>100_bases
GGCAGGATGGTCCGCGAGATAGATGCAGCCGTCGAGGCGCCCGGGGTATCCGGGGCCCGATGGCTGTGCTTGTGCACCGG
CTTTGTTGAGCCCGTACCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 753; Mature: 752

Protein sequence:

>753_residues
MGKFRLTTHEEELQAEREYIAGLYERLDAERARVKGRYRSALRGPVDQQNGGAMAERDDEVRALARQAQRLDVADDGLCF
GRLDAITGERSYVGRIGLLDESNDYEPLLIDWRAPAAQAFYIATSAHPENTRRRRQFRTRGRHVDDFTDEILGRPDGEDH
DGERGTLSDAALLAAVNAPRGHGMRDIVATIQAEQDRIIRLDHPGVLVIEGGPGTGKTVVALHRVAYLLYTQRKRMERHG
VLVVGPNAAFLGHISRVLPSLGETNVVFTTAGDLVPGLKVTAEDDEEAARVKGSLQILDVLAAAVADRQRAPENPMPIQL
ADVSVRIDADIAQWAIEEARASKLPHNEARTVFTDVLTWALTERAIPRIGKGWLTREDRKAWEHLRAELLDELGDHEGFA
AALDALWPMLTPETLLSELYTSPERLRAAGADPALARRIGDAWTVSDVPLLDELVDLLGRDKAAEEAAERERRAEAEYAA
GVLDLMTGREDMMDDEDHLFATDLLGAEDLAERFTERDTRDLVERASADRDWTYGHIVIDEAQELSEMDWRVLMRRCPSR
SFTVVGDLAQRRSAAGATSWEAMLQPYVPGRWLYRPLSVNYRTPAEIMAVASAVLAEFAPGTQPPESVRSSGVLPWSRRL
SEGELPKAIEEFVLNEKGREGTSVVIGPPGVPGTVPASETKGLEFDAVLVVEPERILADGPRGAAELYVALTRATQRLGV
LHVAPLPQPLIGLTESTTGPGPDHRVMPTGVAQ

Sequences:

>Translated_753_residues
MGKFRLTTHEEELQAEREYIAGLYERLDAERARVKGRYRSALRGPVDQQNGGAMAERDDEVRALARQAQRLDVADDGLCF
GRLDAITGERSYVGRIGLLDESNDYEPLLIDWRAPAAQAFYIATSAHPENTRRRRQFRTRGRHVDDFTDEILGRPDGEDH
DGERGTLSDAALLAAVNAPRGHGMRDIVATIQAEQDRIIRLDHPGVLVIEGGPGTGKTVVALHRVAYLLYTQRKRMERHG
VLVVGPNAAFLGHISRVLPSLGETNVVFTTAGDLVPGLKVTAEDDEEAARVKGSLQILDVLAAAVADRQRAPENPMPIQL
ADVSVRIDADIAQWAIEEARASKLPHNEARTVFTDVLTWALTERAIPRIGKGWLTREDRKAWEHLRAELLDELGDHEGFA
AALDALWPMLTPETLLSELYTSPERLRAAGADPALARRIGDAWTVSDVPLLDELVDLLGRDKAAEEAAERERRAEAEYAA
GVLDLMTGREDMMDDEDHLFATDLLGAEDLAERFTERDTRDLVERASADRDWTYGHIVIDEAQELSEMDWRVLMRRCPSR
SFTVVGDLAQRRSAAGATSWEAMLQPYVPGRWLYRPLSVNYRTPAEIMAVASAVLAEFAPGTQPPESVRSSGVLPWSRRL
SEGELPKAIEEFVLNEKGREGTSVVIGPPGVPGTVPASETKGLEFDAVLVVEPERILADGPRGAAELYVALTRATQRLGV
LHVAPLPQPLIGLTESTTGPGPDHRVMPTGVAQ
>Mature_752_residues
GKFRLTTHEEELQAEREYIAGLYERLDAERARVKGRYRSALRGPVDQQNGGAMAERDDEVRALARQAQRLDVADDGLCFG
RLDAITGERSYVGRIGLLDESNDYEPLLIDWRAPAAQAFYIATSAHPENTRRRRQFRTRGRHVDDFTDEILGRPDGEDHD
GERGTLSDAALLAAVNAPRGHGMRDIVATIQAEQDRIIRLDHPGVLVIEGGPGTGKTVVALHRVAYLLYTQRKRMERHGV
LVVGPNAAFLGHISRVLPSLGETNVVFTTAGDLVPGLKVTAEDDEEAARVKGSLQILDVLAAAVADRQRAPENPMPIQLA
DVSVRIDADIAQWAIEEARASKLPHNEARTVFTDVLTWALTERAIPRIGKGWLTREDRKAWEHLRAELLDELGDHEGFAA
ALDALWPMLTPETLLSELYTSPERLRAAGADPALARRIGDAWTVSDVPLLDELVDLLGRDKAAEEAAERERRAEAEYAAG
VLDLMTGREDMMDDEDHLFATDLLGAEDLAERFTERDTRDLVERASADRDWTYGHIVIDEAQELSEMDWRVLMRRCPSRS
FTVVGDLAQRRSAAGATSWEAMLQPYVPGRWLYRPLSVNYRTPAEIMAVASAVLAEFAPGTQPPESVRSSGVLPWSRRLS
EGELPKAIEEFVLNEKGREGTSVVIGPPGVPGTVPASETKGLEFDAVLVVEPERILADGPRGAAELYVALTRATQRLGVL
HVAPLPQPLIGLTESTTGPGPDHRVMPTGVAQ

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 82936; Mature: 82805

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKFRLTTHEEELQAEREYIAGLYERLDAERARVKGRYRSALRGPVDQQNGGAMAERDDE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
VRALARQAQRLDVADDGLCFGRLDAITGERSYVGRIGLLDESNDYEPLLIDWRAPAAQAF
HHHHHHHHHHCCCCCCCCEEHHHHHCCCCCHHHEEEEEECCCCCCCCEEEECCCCCCEEE
YIATSAHPENTRRRRQFRTRGRHVDDFTDEILGRPDGEDHDGERGTLSDAALLAAVNAPR
EEEECCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEECCCC
GHGMRDIVATIQAEQDRIIRLDHPGVLVIEGGPGTGKTVVALHRVAYLLYTQRKRMERHG
CCCHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
VLVVGPNAAFLGHISRVLPSLGETNVVFTTAGDLVPGLKVTAEDDEEAARVKGSLQILDV
EEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHH
LAAAVADRQRAPENPMPIQLADVSVRIDADIAQWAIEEARASKLPHNEARTVFTDVLTWA
HHHHHHHHHCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LTERAIPRIGKGWLTREDRKAWEHLRAELLDELGDHEGFAAALDALWPMLTPETLLSELY
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHH
TSPERLRAAGADPALARRIGDAWTVSDVPLLDELVDLLGRDKAAEEAAERERRAEAEYAA
CCHHHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
GVLDLMTGREDMMDDEDHLFATDLLGAEDLAERFTERDTRDLVERASADRDWTYGHIVID
HHHHHHCCCHHHCCCCCCEEHHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEEC
EAQELSEMDWRVLMRRCPSRSFTVVGDLAQRRSAAGATSWEAMLQPYVPGRWLYRPLSVN
CHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCCC
YRTPAEIMAVASAVLAEFAPGTQPPESVRSSGVLPWSRRLSEGELPKAIEEFVLNEKGRE
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHCCCCCC
GTSVVIGPPGVPGTVPASETKGLEFDAVLVVEPERILADGPRGAAELYVALTRATQRLGV
CCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCHHHHHHHHHHHHHHHCE
LHVAPLPQPLIGLTESTTGPGPDHRVMPTGVAQ
EEECCCCCHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GKFRLTTHEEELQAEREYIAGLYERLDAERARVKGRYRSALRGPVDQQNGGAMAERDDE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
VRALARQAQRLDVADDGLCFGRLDAITGERSYVGRIGLLDESNDYEPLLIDWRAPAAQAF
HHHHHHHHHHCCCCCCCCEEHHHHHCCCCCHHHEEEEEECCCCCCCCEEEECCCCCCEEE
YIATSAHPENTRRRRQFRTRGRHVDDFTDEILGRPDGEDHDGERGTLSDAALLAAVNAPR
EEEECCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEECCCC
GHGMRDIVATIQAEQDRIIRLDHPGVLVIEGGPGTGKTVVALHRVAYLLYTQRKRMERHG
CCCHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
VLVVGPNAAFLGHISRVLPSLGETNVVFTTAGDLVPGLKVTAEDDEEAARVKGSLQILDV
EEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHH
LAAAVADRQRAPENPMPIQLADVSVRIDADIAQWAIEEARASKLPHNEARTVFTDVLTWA
HHHHHHHHHCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LTERAIPRIGKGWLTREDRKAWEHLRAELLDELGDHEGFAAALDALWPMLTPETLLSELY
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHH
TSPERLRAAGADPALARRIGDAWTVSDVPLLDELVDLLGRDKAAEEAAERERRAEAEYAA
CCHHHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
GVLDLMTGREDMMDDEDHLFATDLLGAEDLAERFTERDTRDLVERASADRDWTYGHIVID
HHHHHHCCCHHHCCCCCCEEHHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEEC
EAQELSEMDWRVLMRRCPSRSFTVVGDLAQRRSAAGATSWEAMLQPYVPGRWLYRPLSVN
CHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEECCCC
YRTPAEIMAVASAVLAEFAPGTQPPESVRSSGVLPWSRRLSEGELPKAIEEFVLNEKGRE
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHCCCCCC
GTSVVIGPPGVPGTVPASETKGLEFDAVLVVEPERILADGPRGAAELYVALTRATQRLGV
CCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCHHHHHHHHHHHHHHHCE
LHVAPLPQPLIGLTESTTGPGPDHRVMPTGVAQ
EEECCCCCHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]