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The map label for this gene is nadA [H]

Identifier: 169629759

GI number: 169629759

Start: 2715714

End: 2716742

Strand: Reverse

Name: nadA [H]

Synonym: MAB_2674c

Alternate gene names: 169629759

Gene position: 2716742-2715714 (Counterclockwise)

Preceding gene: 169629762

Following gene: 169629758

Centisome position: 53.61

GC content: 65.31

Gene sequence:

>1029_bases
ATGACCGCAGCTGACGTAGTACTTGACGGTGTGATTGACGGTCCCGGTGGATACACCGGTGTGGAGGGCGATGCCCGCTG
GGCCGAGATGGTGCGCCGACTGGCCGAACAGCGCGGTGCGACAGTGCTCGCGCACAACTATCAGCTGCCGGCCATTCAGG
ACGTGGCGGACCACGTGGGTGATTCACTGGCCTTGTCCCGTATCGCCGCCGAGGCGCCCGAAGACACGATCGTTTTCTGT
GGCGTGCACTTCATGGCGGAAACTGCCAAGATCCTCAGCCCCGAGAAGACCGTGCTCATCCCCGACCAGCGTGCGGGATG
CTCGCTGGCCGATTCCATCACCGCCGACCAACTGCGCGACTGGAAGGCGGAGTTCCCTGACGCGGTCGTCGTCTCGTACG
TCAACACCACGGCCGCCGTGAAGGCGCTCACCGATATCTGCTGCACCTCGTCGAACGCGGTCGACGTGGTCGCTTCCATA
GATCCCGACCGTGAGGTGCTGTTCTGCCCGGATCAGTTCCTCGGCGCACACGTCAAGCGGGTCACCGGCCGTCAGAATCT
GCACATCTGGGCGGGTGAATGCCATGTCCACGCCGGTATCAATGGCGACGAGCTGGCAGGACAGGCCCGCTCGCACCCGA
ATGCCGAGCTGTTTGTGCATCCCGAATGCGGCTGCGCGACATCGGCGCTGTACCTGGCCGGCGAGGGCGCCGTTCCCGAC
GATCGGGTGAAAATCCTCTCGACGGGCGGCATGCTCGACGCCGCCCGCGAGACCCGGGCCCGCGAAGTGCTGGTGGCCAC
CGAGGTGGGCATGCTGCACCAGTTACGCAAGGCGGCTCCCGATGTGAACTTCCTGGCGGTCAACGACAGGGCCTCGTGCA
CCTACATGAAGATGATCACTCCGGCGGCGTTGTTGCGATGCCTGGTGGAGGGGCGCGATGAGGTGGATGTCGATCCGGAC
ACCGCGCGCCTGGCCCGCCGCAGCGTCCAGCGGATGATCGAGATCGGACAACCCGGCGGCGGAGAATGA

Upstream 100 bases:

>100_bases
GGTGCTAGTATGGACCATGTTTTCGATCATAAGTCGAAAACCTCGGTCATCCAAGCCCGGCCCGGCTGTAGACCGAGACC
CGAGGCGCGAGGAGGCGGCC

Downstream 100 bases:

>100_bases
CCATGCCGGCGGGGACCACCTGGCGCACTGACGCAGATGTGGTCGTCGTCGGTGCGGGTGTCGCCGGGCTTGCGGCCGCC
TTGGCGGTGCACCGGCGTGG

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTAADVVLDGVIDGPGGYTGVEGDARWAEMVRRLAEQRGATVLAHNYQLPAIQDVADHVGDSLALSRIAAEAPEDTIVFC
GVHFMAETAKILSPEKTVLIPDQRAGCSLADSITADQLRDWKAEFPDAVVVSYVNTTAAVKALTDICCTSSNAVDVVASI
DPDREVLFCPDQFLGAHVKRVTGRQNLHIWAGECHVHAGINGDELAGQARSHPNAELFVHPECGCATSALYLAGEGAVPD
DRVKILSTGGMLDAARETRAREVLVATEVGMLHQLRKAAPDVNFLAVNDRASCTYMKMITPAALLRCLVEGRDEVDVDPD
TARLARRSVQRMIEIGQPGGGE

Sequences:

>Translated_342_residues
MTAADVVLDGVIDGPGGYTGVEGDARWAEMVRRLAEQRGATVLAHNYQLPAIQDVADHVGDSLALSRIAAEAPEDTIVFC
GVHFMAETAKILSPEKTVLIPDQRAGCSLADSITADQLRDWKAEFPDAVVVSYVNTTAAVKALTDICCTSSNAVDVVASI
DPDREVLFCPDQFLGAHVKRVTGRQNLHIWAGECHVHAGINGDELAGQARSHPNAELFVHPECGCATSALYLAGEGAVPD
DRVKILSTGGMLDAARETRAREVLVATEVGMLHQLRKAAPDVNFLAVNDRASCTYMKMITPAALLRCLVEGRDEVDVDPD
TARLARRSVQRMIEIGQPGGGE
>Mature_341_residues
TAADVVLDGVIDGPGGYTGVEGDARWAEMVRRLAEQRGATVLAHNYQLPAIQDVADHVGDSLALSRIAAEAPEDTIVFCG
VHFMAETAKILSPEKTVLIPDQRAGCSLADSITADQLRDWKAEFPDAVVVSYVNTTAAVKALTDICCTSSNAVDVVASID
PDREVLFCPDQFLGAHVKRVTGRQNLHIWAGECHVHAGINGDELAGQARSHPNAELFVHPECGCATSALYLAGEGAVPDD
RVKILSTGGMLDAARETRAREVLVATEVGMLHQLRKAAPDVNFLAVNDRASCTYMKMITPAALLRCLVEGRDEVDVDPDT
ARLARRSVQRMIEIGQPGGGE

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=333, Percent_Identity=32.7327327327327, Blast_Score=160, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 36563; Mature: 36432

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAADVVLDGVIDGPGGYTGVEGDARWAEMVRRLAEQRGATVLAHNYQLPAIQDVADHVG
CCHHHEEEECEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHC
DSLALSRIAAEAPEDTIVFCGVHFMAETAKILSPEKTVLIPDQRAGCSLADSITADQLRD
CHHHHHHHHHCCCCCCEEEECHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHCCHHHHHH
WKAEFPDAVVVSYVNTTAAVKALTDICCTSSNAVDVVASIDPDREVLFCPDQFLGAHVKR
HHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCHHHHHHHHHH
VTGRQNLHIWAGECHVHAGINGDELAGQARSHPNAELFVHPECGCATSALYLAGEGAVPD
HCCCCCEEEEEEEEEEEECCCHHHHCCHHCCCCCCEEEECCCCCCCCCEEEEECCCCCCC
DRVKILSTGGMLDAARETRAREVLVATEVGMLHQLRKAAPDVNFLAVNDRASCTYMKMIT
CCEEEEECCCCHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHH
PAALLRCLVEGRDEVDVDPDTARLARRSVQRMIEIGQPGGGE
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TAADVVLDGVIDGPGGYTGVEGDARWAEMVRRLAEQRGATVLAHNYQLPAIQDVADHVG
CHHHEEEECEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHC
DSLALSRIAAEAPEDTIVFCGVHFMAETAKILSPEKTVLIPDQRAGCSLADSITADQLRD
CHHHHHHHHHCCCCCCEEEECHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHCCHHHHHH
WKAEFPDAVVVSYVNTTAAVKALTDICCTSSNAVDVVASIDPDREVLFCPDQFLGAHVKR
HHHHCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCHHHHHHHHHH
VTGRQNLHIWAGECHVHAGINGDELAGQARSHPNAELFVHPECGCATSALYLAGEGAVPD
HCCCCCEEEEEEEEEEEECCCHHHHCCHHCCCCCCEEEECCCCCCCCCEEEEECCCCCCC
DRVKILSTGGMLDAARETRAREVLVATEVGMLHQLRKAAPDVNFLAVNDRASCTYMKMIT
CCEEEEECCCCHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHH
PAALLRCLVEGRDEVDVDPDTARLARRSVQRMIEIGQPGGGE
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA