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The map label for this gene is acdA [H]

Identifier: 169629581

GI number: 169629581

Start: 2549757

End: 2550986

Strand: Direct

Name: acdA [H]

Synonym: MAB_2495

Alternate gene names: 169629581

Gene position: 2549757-2550986 (Clockwise)

Preceding gene: 169629578

Following gene: 169629582

Centisome position: 50.32

GC content: 63.17

Gene sequence:

>1230_bases
ATGGACCTGGCCTTCTCGGCAGAGGAAGAACAATTCCGTACCGAAGTCCGGGAGTTCCTGGACGCGAACCTCACCGCGGA
GCTGCGGGCGGCCGGGCGTCTGCAGACCAGCGTGTACAGCGATCACGAGGCAAGTATGCGGTGGCAGGCGATCCTGCACC
GGAAGGGATGGGCCGCGCCGGCTTGGCCGGTCAAATACGGCGGGCAGCCGTGGAGTCTTGCCCAGCACTACATCTTTTCG
GTTGAATCGATGGTTGCGGGGGCACCTTCACTGTCGCCCATGGGAATTCGGATGGTCGCACATGCCATCATCAAGTTCGG
CAGCCCGGAACAGAAAGAGTTCTTCCTGCCCCGGATCCTCACGGGCGAGGTGTTCTTCTGTCAGGGGTACAGCGAGCCCG
AGTCGGGGTCTGACCTGGCCTCGTTGCAGATGTCGGCCGTTGCCGACGGTGATGACTTCGTCCTCAATGGCTCCAAGATC
TGGACCACCCATGCGCGCGAGGCGAATTGGATGTTCGCCCTTGTTCGCACCACCAAGGGGCCCAAGAAACAGCTCGGTAT
CACCTTCATTCTCATCGACTTCACGTCGCCGGGCATAGACGTCAAACCCTTGGTGATGAGTTCCGGCGAGGAGGTACAGA
ATGTCGTGTTCTTCGACAACGTGCGTGTGCCGCGGGCCAATGTGCTCGGGGAGGTTGACCAGGGGTGGACCGTCGCGAAG
TACCTCCTTGAGTTCGAGCGCGGCGGCGGGGCCGTGGCACCCATGCTGCAGGTGGGCCTCGATCAGCTGAGCGTTGACGC
GCGGTCGGTGCCTGCCGAGAACGGCACCCTGGCAGACGATCCCGTGTTCTGTGCCAAACTGGCCGACCTGGCGATTCGTG
TCGACGTACTCGAGGTCCTCGAGCATCGCGTGCTGGCGGTCGTGGCAGGCGGCGGCAATCCGGGCGCGGCATCCTCGATG
CTGAAAATCCTTGGCACCGAACTATCGCAGGCGTTGACCACACTGACGTTAGAGGCGGCAGGGCCGCGGGGCCGGGCATA
CCAGCCTCACGTCACCAAGCCGGGTGGCCCGGTCGTCGAGTACACCCCGCCCGCAGACGGTTATCACAGCGGCGAGCTGT
GGCAGGCGGTGGCGCCGTTGCACTATTTCAACGATCGCGCCGGGTCGATCTATGCCGGTTCCAACGAGATTCAACGCAAC
ATCCTCGCCAAGGCCCAGCTGGGTCTCTGA

Upstream 100 bases:

>100_bases
ATTGCCTGGGACCGGAACGGGTATTAATCTGAATGCGCCTGCATCCAGATCGGTCGCAGTCGTCGTTTTCCCACCGCAGA
CTCGACACCACGGAGCGCAC

Downstream 100 bases:

>100_bases
CAGACAAGAGCGAATATCACCATGGATTTCAGCCTCACCGACGAACAACAACTCCTGAAGCACTCGATATCGGATTTTCT
GTCTAATCGGTACGCCTTGA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MDLAFSAEEEQFRTEVREFLDANLTAELRAAGRLQTSVYSDHEASMRWQAILHRKGWAAPAWPVKYGGQPWSLAQHYIFS
VESMVAGAPSLSPMGIRMVAHAIIKFGSPEQKEFFLPRILTGEVFFCQGYSEPESGSDLASLQMSAVADGDDFVLNGSKI
WTTHAREANWMFALVRTTKGPKKQLGITFILIDFTSPGIDVKPLVMSSGEEVQNVVFFDNVRVPRANVLGEVDQGWTVAK
YLLEFERGGGAVAPMLQVGLDQLSVDARSVPAENGTLADDPVFCAKLADLAIRVDVLEVLEHRVLAVVAGGGNPGAASSM
LKILGTELSQALTTLTLEAAGPRGRAYQPHVTKPGGPVVEYTPPADGYHSGELWQAVAPLHYFNDRAGSIYAGSNEIQRN
ILAKAQLGL

Sequences:

>Translated_409_residues
MDLAFSAEEEQFRTEVREFLDANLTAELRAAGRLQTSVYSDHEASMRWQAILHRKGWAAPAWPVKYGGQPWSLAQHYIFS
VESMVAGAPSLSPMGIRMVAHAIIKFGSPEQKEFFLPRILTGEVFFCQGYSEPESGSDLASLQMSAVADGDDFVLNGSKI
WTTHAREANWMFALVRTTKGPKKQLGITFILIDFTSPGIDVKPLVMSSGEEVQNVVFFDNVRVPRANVLGEVDQGWTVAK
YLLEFERGGGAVAPMLQVGLDQLSVDARSVPAENGTLADDPVFCAKLADLAIRVDVLEVLEHRVLAVVAGGGNPGAASSM
LKILGTELSQALTTLTLEAAGPRGRAYQPHVTKPGGPVVEYTPPADGYHSGELWQAVAPLHYFNDRAGSIYAGSNEIQRN
ILAKAQLGL
>Mature_409_residues
MDLAFSAEEEQFRTEVREFLDANLTAELRAAGRLQTSVYSDHEASMRWQAILHRKGWAAPAWPVKYGGQPWSLAQHYIFS
VESMVAGAPSLSPMGIRMVAHAIIKFGSPEQKEFFLPRILTGEVFFCQGYSEPESGSDLASLQMSAVADGDDFVLNGSKI
WTTHAREANWMFALVRTTKGPKKQLGITFILIDFTSPGIDVKPLVMSSGEEVQNVVFFDNVRVPRANVLGEVDQGWTVAK
YLLEFERGGGAVAPMLQVGLDQLSVDARSVPAENGTLADDPVFCAKLADLAIRVDVLEVLEHRVLAVVAGGGNPGAASSM
LKILGTELSQALTTLTLEAAGPRGRAYQPHVTKPGGPVVEYTPPADGYHSGELWQAVAPLHYFNDRAGSIYAGSNEIQRN
ILAKAQLGL

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=310, Percent_Identity=28.3870967741935, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI226958412, Length=269, Percent_Identity=27.5092936802974, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4557231, Length=312, Percent_Identity=25, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI187960098, Length=313, Percent_Identity=25.8785942492013, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI226958414, Length=191, Percent_Identity=29.3193717277487, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI76496475, Length=280, Percent_Identity=31.4285714285714, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4557235, Length=280, Percent_Identity=31.4285714285714, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4501859, Length=418, Percent_Identity=26.3157894736842, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI7656849, Length=319, Percent_Identity=28.5266457680251, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI4501857, Length=408, Percent_Identity=23.0392156862745, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI21361497, Length=298, Percent_Identity=28.1879194630872, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4503943, Length=151, Percent_Identity=29.1390728476821, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI7669494, Length=151, Percent_Identity=29.1390728476821, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87081958, Length=316, Percent_Identity=24.6835443037975, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17570075, Length=424, Percent_Identity=24.2924528301887, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=385, Percent_Identity=29.8701298701299, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17534899, Length=315, Percent_Identity=26.6666666666667, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17538396, Length=256, Percent_Identity=27.734375, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=24.2744063324538, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32563615, Length=251, Percent_Identity=30.6772908366534, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17506239, Length=217, Percent_Identity=32.258064516129, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17505929, Length=316, Percent_Identity=25.6329113924051, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17551932, Length=205, Percent_Identity=28.780487804878, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71990804, Length=217, Percent_Identity=31.7972350230415, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71985184, Length=200, Percent_Identity=31.5, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71985192, Length=201, Percent_Identity=31.3432835820896, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71982178, Length=234, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21355753, Length=235, Percent_Identity=31.063829787234, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24646207, Length=413, Percent_Identity=26.1501210653753, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281363737, Length=170, Percent_Identity=34.1176470588235, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24666513, Length=178, Percent_Identity=36.5168539325843, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24660351, Length=168, Percent_Identity=31.547619047619, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21356377, Length=307, Percent_Identity=26.7100977198697, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44357; Mature: 44357

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLAFSAEEEQFRTEVREFLDANLTAELRAAGRLQTSVYSDHEASMRWQAILHRKGWAAP
CCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCCCC
AWPVKYGGQPWSLAQHYIFSVESMVAGAPSLSPMGIRMVAHAIIKFGSPEQKEFFLPRIL
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCEEE
TGEVFFCQGYSEPESGSDLASLQMSAVADGDDFVLNGSKIWTTHAREANWMFALVRTTKG
CCCEEEEECCCCCCCCCCHHHEEHHEECCCCCEEEECCEEEEECCCCCCEEEEEEECCCC
PKKQLGITFILIDFTSPGIDVKPLVMSSGEEVQNVVFFDNVRVPRANVLGEVDQGWTVAK
CCHHCCEEEEEEEECCCCCCEEEHEECCCHHHCEEEEECCCCCCCHHHCCCCCCCHHHHH
YLLEFERGGGAVAPMLQVGLDQLSVDARSVPAENGTLADDPVFCAKLADLAIRVDVLEVL
HHHHHHCCCCCCHHHHHHCHHHHCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EHRVLAVVAGGGNPGAASSMLKILGTELSQALTTLTLEAAGPRGRAYQPHVTKPGGPVVE
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCEEE
YTPPADGYHSGELWQAVAPLHYFNDRAGSIYAGSNEIQRNILAKAQLGL
ECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLAFSAEEEQFRTEVREFLDANLTAELRAAGRLQTSVYSDHEASMRWQAILHRKGWAAP
CCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCCCC
AWPVKYGGQPWSLAQHYIFSVESMVAGAPSLSPMGIRMVAHAIIKFGSPEQKEFFLPRIL
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCEEE
TGEVFFCQGYSEPESGSDLASLQMSAVADGDDFVLNGSKIWTTHAREANWMFALVRTTKG
CCCEEEEECCCCCCCCCCHHHEEHHEECCCCCEEEECCEEEEECCCCCCEEEEEEECCCC
PKKQLGITFILIDFTSPGIDVKPLVMSSGEEVQNVVFFDNVRVPRANVLGEVDQGWTVAK
CCHHCCEEEEEEEECCCCCCEEEHEECCCHHHCEEEEECCCCCCCHHHCCCCCCCHHHHH
YLLEFERGGGAVAPMLQVGLDQLSVDARSVPAENGTLADDPVFCAKLADLAIRVDVLEVL
HHHHHHCCCCCCHHHHHHCHHHHCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EHRVLAVVAGGGNPGAASSMLKILGTELSQALTTLTLEAAGPRGRAYQPHVTKPGGPVVE
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCEEE
YTPPADGYHSGELWQAVAPLHYFNDRAGSIYAGSNEIQRNILAKAQLGL
ECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]