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The map label for this gene is fabD [H]

Identifier: 169629121

GI number: 169629121

Start: 2033648

End: 2034589

Strand: Direct

Name: fabD [H]

Synonym: MAB_2034

Alternate gene names: 169629121

Gene position: 2033648-2034589 (Clockwise)

Preceding gene: 169629120

Following gene: 169629122

Centisome position: 40.13

GC content: 63.38

Gene sequence:

>942_bases
GTGTACAACTACATCGTCACGTCCCCTGGGCAAGGTGTGCAGAAGCCGGGCATGCTCGATCCTTGGCTGACCCTGTCCGC
TGCGCGCGATCGCATCGCGATCTGGTCTGACGCGGTCAAGTTCGACCTGGTGACCGCCAGCAGAGATGAGAACTCCTTGC
GTGATACCGCCGTCGCTCAGCCCGTCATCATCGCGGCGGCCCTGCTGTCACTGAGCGTGCTGCGCGAGAAAGTCGATATC
TCCGGAGACGGCGCACTGTTCGCCGGCCACTCGGTGGGTGAGCTCGCTGCCGGGGTTGGGGCGGGCTATCTGACTGATGA
GGCCGCGCTGACGTTGGCCGGCGTGAGGGGCGGCGCGATGTCGTCGGCATGCGCCCTGGCCGCCACCGGTATGGCCGCGG
TGATGCCGACGAAGAGGGGCGGCGCGTCAGATGACGAGATTGTGGCTAAAACGCATGAACATGGCCTCTCGACGGCCAAC
CGCAACGGCTGCAACCAGTTCGTCGTCGCCGGGCCCCTCGACGCTGTCGAACGTTTTGCCGACGCGCCACCCGAGGGCAT
GCGCGTCATGAAACTGGATGTGGCGGGTGCCTTTCACACCTCGGCGATGGACACCGCGATATCGCCGTTCGCAGAAGCAG
TGAACAGCTGTCCGGTTTTGACCCCGTCGTCCCCCATGATCGGCAATCGTGACGGCGCGATCATCGAAGGTCCCATGGAC
TTCAAAAAGCGGTTGATCGCCCAGATCAATTCGGTGGTCCGTTGGGATCTGTGTGCCGCCACGATCGCTTCGGCAGCAAC
CGCCGACACCGTCGTCATCGAACTTGCGCCGAGTGGACCGCTGACCCGTCTCGCCGAACGTCTCAACGCAGAATTTCAGA
CCGTTGCCATCCGGGAGCCAGGGGACGTGGAGTTGCTTTCCGGCGAGTTTGCGATTGATTAG

Upstream 100 bases:

>100_bases
CTGTCTCATCCAGGTGTGCAATGTCAGCCCAATCATCTAGGCGGCGATGCAAAAAGCTAGTGCCGGAGAATATCTGACCC
CACTGGGAAAGCGAGGAAGT

Downstream 100 bases:

>100_bases
CCGAGTTCCGTGCGAACACTATGCGTAACAGGGCGAATAGCCGAGAAGGGAGGCAACGTGACAGACACGCGACCGCATCA
GGACACGGTGGACGCGCCTG

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MYNYIVTSPGQGVQKPGMLDPWLTLSAARDRIAIWSDAVKFDLVTASRDENSLRDTAVAQPVIIAAALLSLSVLREKVDI
SGDGALFAGHSVGELAAGVGAGYLTDEAALTLAGVRGGAMSSACALAATGMAAVMPTKRGGASDDEIVAKTHEHGLSTAN
RNGCNQFVVAGPLDAVERFADAPPEGMRVMKLDVAGAFHTSAMDTAISPFAEAVNSCPVLTPSSPMIGNRDGAIIEGPMD
FKKRLIAQINSVVRWDLCAATIASAATADTVVIELAPSGPLTRLAERLNAEFQTVAIREPGDVELLSGEFAID

Sequences:

>Translated_313_residues
MYNYIVTSPGQGVQKPGMLDPWLTLSAARDRIAIWSDAVKFDLVTASRDENSLRDTAVAQPVIIAAALLSLSVLREKVDI
SGDGALFAGHSVGELAAGVGAGYLTDEAALTLAGVRGGAMSSACALAATGMAAVMPTKRGGASDDEIVAKTHEHGLSTAN
RNGCNQFVVAGPLDAVERFADAPPEGMRVMKLDVAGAFHTSAMDTAISPFAEAVNSCPVLTPSSPMIGNRDGAIIEGPMD
FKKRLIAQINSVVRWDLCAATIASAATADTVVIELAPSGPLTRLAERLNAEFQTVAIREPGDVELLSGEFAID
>Mature_313_residues
MYNYIVTSPGQGVQKPGMLDPWLTLSAARDRIAIWSDAVKFDLVTASRDENSLRDTAVAQPVIIAAALLSLSVLREKVDI
SGDGALFAGHSVGELAAGVGAGYLTDEAALTLAGVRGGAMSSACALAATGMAAVMPTKRGGASDDEIVAKTHEHGLSTAN
RNGCNQFVVAGPLDAVERFADAPPEGMRVMKLDVAGAFHTSAMDTAISPFAEAVNSCPVLTPSSPMIGNRDGAIIEGPMD
FKKRLIAQINSVVRWDLCAATIASAATADTVVIELAPSGPLTRLAERLNAEFQTVAIREPGDVELLSGEFAID

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Escherichia coli, GI1787334, Length=311, Percent_Identity=27.0096463022508, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71984332, Length=264, Percent_Identity=26.1363636363636, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32478; Mature: 32478

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNYIVTSPGQGVQKPGMLDPWLTLSAARDRIAIWSDAVKFDLVTASRDENSLRDTAVAQ
CCCEEEECCCCCCCCCCCCCCHHHHHHCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHH
PVIIAAALLSLSVLREKVDISGDGALFAGHSVGELAAGVGAGYLTDEAALTLAGVRGGAM
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHCCCCCCCCCHHEEEECCCCCCH
SSACALAATGMAAVMPTKRGGASDDEIVAKTHEHGLSTANRNGCNQFVVAGPLDAVERFA
HHHHHHHHCCHHEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHH
DAPPEGMRVMKLDVAGAFHTSAMDTAISPFAEAVNSCPVLTPSSPMIGNRDGAIIEGPMD
CCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCHH
FKKRLIAQINSVVRWDLCAATIASAATADTVVIELAPSGPLTRLAERLNAEFQTVAIREP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCEEEEEEECC
GDVELLSGEFAID
CCEEEECCCEECC
>Mature Secondary Structure
MYNYIVTSPGQGVQKPGMLDPWLTLSAARDRIAIWSDAVKFDLVTASRDENSLRDTAVAQ
CCCEEEECCCCCCCCCCCCCCHHHHHHCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHH
PVIIAAALLSLSVLREKVDISGDGALFAGHSVGELAAGVGAGYLTDEAALTLAGVRGGAM
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHCCCCCCCCCHHEEEECCCCCCH
SSACALAATGMAAVMPTKRGGASDDEIVAKTHEHGLSTANRNGCNQFVVAGPLDAVERFA
HHHHHHHHCCHHEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHH
DAPPEGMRVMKLDVAGAFHTSAMDTAISPFAEAVNSCPVLTPSSPMIGNRDGAIIEGPMD
CCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCHH
FKKRLIAQINSVVRWDLCAATIASAATADTVVIELAPSGPLTRLAERLNAEFQTVAIREP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCEEEEEEECC
GDVELLSGEFAID
CCEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]