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The map label for this gene is papA5 [H]

Identifier: 169629122

GI number: 169629122

Start: 2034647

End: 2035936

Strand: Direct

Name: papA5 [H]

Synonym: MAB_2035

Alternate gene names: 169629122

Gene position: 2034647-2035936 (Clockwise)

Preceding gene: 169629121

Following gene: 169629123

Centisome position: 40.15

GC content: 57.67

Gene sequence:

>1290_bases
GTGACAGACACGCGACCGCATCAGGACACGGTGGACGCGCCTGGCGAGCCAATTCGTCCACTTAGCCGCCTGGAGACATA
CTTCACTTTCGGGTTTGGTCATTTCGGCGGGCAGTCAATGCTTATCTCGGGGGATTTAGATATCGAGGCGCTGAATGACA
CTTGTATTGAGATGCAGCTCCGCCACGAATCCCTGCGAAGCATCATCCGTAAGAATGATCAAGTCCCCGAGTTTGTGGCG
ACGCACCGACCGCCCAAATCGATCCGCGTATTCGAGGGAGAAGACCTTGGGGCCCGGTCCACTGGGCGTGAGGCCGTATT
CGATCAGACGCAGCAGCTTTTCTACGTCGATCTGCTGCTCGGGGACGGCCAGGCCCGCGTAACGTTCTTCGTCCACCACT
CCATTGCGGACGGTCGCCACGGATCTGCGATCCTCATCGAGTTTTGGAGCCTTTACGTTCAGCGCGTCGAGGAAGGGCAG
TTCCCGCCGATCCTCACCCAAAAATTCCCACAGTCGGGGGAGTACTTCCTGAACCGCACTCAGTATCCGGGCGCGGATCC
GAGCGTGAAGGCGGATGAAGTATTGCGTGTGCCGCTGTGGGATGAGGCCGCGCTTGCCCAGAAACTCCCGCCCCCTCGGG
AGCCCGCGCTCGCCAAACAGATGACGTTGGAAAAACTCGGCAGAGCAAGCCTCGCCCGCCTCGGCAATATCGAAAGCATC
TCGATCAACGCGCTTGTGTCCGCAGCTCTGATTCGTGCGCATGTCCGCGCTGGCGACCCAGTCCCACTGTATTTCTATCC
GGTAGATCTTCGCGACTGTGTAACGCCTCCGGTTGCCCCCACCGAAGCGACCAACTTGCTCTCCAACGCATGGTTCGGCG
ATGTTGAGATCGGGCCGGACCTCGTCACACTCGCCAGAAAGATACATGTCCAATTCGACAGGGACTTAGCGGACGGCACA
ATTCACCGAACGCGCGTCAGAAATGAGCCAACGAAGCTTCTCGCTGATAAGTCTTTTGGTGGCGCAATTCATGCCACCCA
GCTAGGTCGAATTCGTGTTCCCCGCCTACCGGGGAATCTGGTCGTAGACGACATCACGTCCAGTCATGCATCGGCATTGG
GGCCAGCTATTTATACGTTCTTGTACGGTCGGGAAGTTTCGGTGTACACGATTGACTCGCTGAATCAACGACTGCGGGTG
GGTTTCCTAGCCGGAAGTTACGAAAAGAGCGATGAGCTTCTTGCGTACATCGAAGACGAACTGACCGCGGCGATAGACGC
TCGCATCTGA

Upstream 100 bases:

>100_bases
AGGGGACGTGGAGTTGCTTTCCGGCGAGTTTGCGATTGATTAGCCGAGTTCCGTGCGAACACTATGCGTAACAGGGCGAA
TAGCCGAGAAGGGAGGCAAC

Downstream 100 bases:

>100_bases
TGGCGTTCCCTCGAGGGCTCGGTGCGTTCGGGCGCAAGGTCATCCGACACGGCTGGTTGGTCGTGGTGATAGCGGTCGTG
GCCTCGCTTGCGTCCGTATC

Product: acyltransferase PapA5

Products: NA

Alternate protein names: Acyltransferase papA5; Phthiocerol/phthiodiolone O-acyltransferase; Polyketide synthase-associated protein A5 [H]

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MTDTRPHQDTVDAPGEPIRPLSRLETYFTFGFGHFGGQSMLISGDLDIEALNDTCIEMQLRHESLRSIIRKNDQVPEFVA
THRPPKSIRVFEGEDLGARSTGREAVFDQTQQLFYVDLLLGDGQARVTFFVHHSIADGRHGSAILIEFWSLYVQRVEEGQ
FPPILTQKFPQSGEYFLNRTQYPGADPSVKADEVLRVPLWDEAALAQKLPPPREPALAKQMTLEKLGRASLARLGNIESI
SINALVSAALIRAHVRAGDPVPLYFYPVDLRDCVTPPVAPTEATNLLSNAWFGDVEIGPDLVTLARKIHVQFDRDLADGT
IHRTRVRNEPTKLLADKSFGGAIHATQLGRIRVPRLPGNLVVDDITSSHASALGPAIYTFLYGREVSVYTIDSLNQRLRV
GFLAGSYEKSDELLAYIEDELTAAIDARI

Sequences:

>Translated_429_residues
MTDTRPHQDTVDAPGEPIRPLSRLETYFTFGFGHFGGQSMLISGDLDIEALNDTCIEMQLRHESLRSIIRKNDQVPEFVA
THRPPKSIRVFEGEDLGARSTGREAVFDQTQQLFYVDLLLGDGQARVTFFVHHSIADGRHGSAILIEFWSLYVQRVEEGQ
FPPILTQKFPQSGEYFLNRTQYPGADPSVKADEVLRVPLWDEAALAQKLPPPREPALAKQMTLEKLGRASLARLGNIESI
SINALVSAALIRAHVRAGDPVPLYFYPVDLRDCVTPPVAPTEATNLLSNAWFGDVEIGPDLVTLARKIHVQFDRDLADGT
IHRTRVRNEPTKLLADKSFGGAIHATQLGRIRVPRLPGNLVVDDITSSHASALGPAIYTFLYGREVSVYTIDSLNQRLRV
GFLAGSYEKSDELLAYIEDELTAAIDARI
>Mature_428_residues
TDTRPHQDTVDAPGEPIRPLSRLETYFTFGFGHFGGQSMLISGDLDIEALNDTCIEMQLRHESLRSIIRKNDQVPEFVAT
HRPPKSIRVFEGEDLGARSTGREAVFDQTQQLFYVDLLLGDGQARVTFFVHHSIADGRHGSAILIEFWSLYVQRVEEGQF
PPILTQKFPQSGEYFLNRTQYPGADPSVKADEVLRVPLWDEAALAQKLPPPREPALAKQMTLEKLGRASLARLGNIESIS
INALVSAALIRAHVRAGDPVPLYFYPVDLRDCVTPPVAPTEATNLLSNAWFGDVEIGPDLVTLARKIHVQFDRDLADGTI
HRTRVRNEPTKLLADKSFGGAIHATQLGRIRVPRLPGNLVVDDITSSHASALGPAIYTFLYGREVSVYTIDSLNQRLRVG
FLAGSYEKSDELLAYIEDELTAAIDARI

Specific function: Catalyzes diesterification of phthiocerol and phthiodiolone with mycocerosic acids, the final step in the phthiocerol and phthiodiolone dimycocerosate esters (PDIM) synthesis. Can directly transfer the mycocerosate bound to the mycocerosic acid synthase (

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyltransferase papA5 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001242 [H]

Pfam domain/function: PF00668 Condensation [H]

EC number: NA

Molecular weight: Translated: 47649; Mature: 47517

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTRPHQDTVDAPGEPIRPLSRLETYFTFGFGHFGGQSMLISGDLDIEALNDTCIEMQL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHEECCCCCCCCEEEEECCCCEEECCCHHHHHHH
RHESLRSIIRKNDQVPEFVATHRPPKSIRVFEGEDLGARSTGREAVFDQTQQLFYVDLLL
HHHHHHHHHHCCCCCCHHHHCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHEEEEEEEE
GDGQARVTFFVHHSIADGRHGSAILIEFWSLYVQRVEEGQFPPILTQKFPQSGEYFLNRT
CCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHEECC
QYPGADPSVKADEVLRVPLWDEAALAQKLPPPREPALAKQMTLEKLGRASLARLGNIESI
CCCCCCCCCCCCCEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
SINALVSAALIRAHVRAGDPVPLYFYPVDLRDCVTPPVAPTEATNLLSNAWFGDVEIGPD
EHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHH
LVTLARKIHVQFDRDLADGTIHRTRVRNEPTKLLADKSFGGAIHATQLGRIRVPRLPGNL
HHHHHHHHHEEECCCCCCCCEEEHHCCCCCHHHEECCCCCCEEEEEECCCEECCCCCCCE
VVDDITSSHASALGPAIYTFLYGREVSVYTIDSLNQRLRVGFLAGSYEKSDELLAYIEDE
EEECCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHH
LTAAIDARI
HHHHHCCCC
>Mature Secondary Structure 
TDTRPHQDTVDAPGEPIRPLSRLETYFTFGFGHFGGQSMLISGDLDIEALNDTCIEMQL
CCCCCCCCCCCCCCCCCCHHHHHHHHHEECCCCCCCCEEEEECCCCEEECCCHHHHHHH
RHESLRSIIRKNDQVPEFVATHRPPKSIRVFEGEDLGARSTGREAVFDQTQQLFYVDLLL
HHHHHHHHHHCCCCCCHHHHCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHEEEEEEEE
GDGQARVTFFVHHSIADGRHGSAILIEFWSLYVQRVEEGQFPPILTQKFPQSGEYFLNRT
CCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHEECC
QYPGADPSVKADEVLRVPLWDEAALAQKLPPPREPALAKQMTLEKLGRASLARLGNIESI
CCCCCCCCCCCCCEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
SINALVSAALIRAHVRAGDPVPLYFYPVDLRDCVTPPVAPTEATNLLSNAWFGDVEIGPD
EHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHH
LVTLARKIHVQFDRDLADGTIHRTRVRNEPTKLLADKSFGGAIHATQLGRIRVPRLPGNL
HHHHHHHHHEEECCCCCCCCEEEHHCCCCCHHHEECCCCCCEEEEEECCCEECCCCCCCE
VVDDITSSHASALGPAIYTFLYGREVSVYTIDSLNQRLRVGFLAGSYEKSDELLAYIEDE
EEECCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHH
LTAAIDARI
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]