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The map label for this gene is 169629120

Identifier: 169629120

GI number: 169629120

Start: 2032838

End: 2033587

Strand: Direct

Name: 169629120

Synonym: MAB_2033

Alternate gene names: NA

Gene position: 2032838-2033587 (Clockwise)

Preceding gene: 169629119

Following gene: 169629121

Centisome position: 40.12

GC content: 61.2

Gene sequence:

>750_bases
GTGCGCAGGACCGATGAGTTACTGCCTGGCAATCCTTGGCTGCGCAGGCTCCGCGACGGGAACGGTGCGACGCGGGTGAT
CTGTTTCCCTCACGCAGGCGGTTCCGCCAGTTACTTCAGGCGATTGGCGAAGATGCTGCCGGCCGACACCGAAGTGCTCG
CCGTGCAATATCCGGGACGGGGAAATAGATTGCGCGAGCAGCCGATAGCGTCAGTGCCCCTGCTCGCAGAAGGCATTGCA
TCGGCCCTGCCCGCCAGCGACAAGCAAGACGTACTTTTCGGTCACAGCCTCGGTGGTCACATCGCGTTCGAAGTGGCGCA
GAGGCTGCCCGTTCGCAAACTTGTGGTGTCCGGGATAGTGGCACCGTCCAAGGTGGTCGATCTCGGTTACCGCCTGCTCA
ACGAAGCCGAAGGAATCGAAAGAATAGCGGCTTTGGGCGGCCTGCCACCCGAGATCCTCGACGACCCTTCGGCCCTCAGC
GCTCTTTTCCCGGTGCTGCGTAGCGATTTCACTGCCGGCGAGACATACACTCCACCGCCGGATGCGACCGTCGCCTGCGA
TATCACCGCGCTCATCGGTGACAAGGATGTCTTGGCCCCACTGGAGCGGGTGAGTTCGTGGCGCGAACACACCCGCGCCA
ATTTCGATCTGCAGGTATTCCGCGGCGGTGGGCATTTCTACTTGGAAGACCACATCGACGAAGTAAGCGCCTGTCTCATC
CAGGTGTGCAATGTCAGCCCAATCATCTAG

Upstream 100 bases:

>100_bases
ATAGCGCTCAAACCCGAAGAGCGCGAACGCATCAGGCATTCTCAAACAGCGTCCGCCGGTTTCATCACCGACGGACGCCT
CGACAGACTAAGGAGGACAG

Downstream 100 bases:

>100_bases
GCGGCGATGCAAAAAGCTAGTGCCGGAGAATATCTGACCCCACTGGGAAAGCGAGGAAGTGTGTACAACTACATCGTCAC
GTCCCCTGGGCAAGGTGTGC

Product: thioesterase

Products: NA

Alternate protein names: ORF-1; Protein X [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MRRTDELLPGNPWLRRLRDGNGATRVICFPHAGGSASYFRRLAKMLPADTEVLAVQYPGRGNRLREQPIASVPLLAEGIA
SALPASDKQDVLFGHSLGGHIAFEVAQRLPVRKLVVSGIVAPSKVVDLGYRLLNEAEGIERIAALGGLPPEILDDPSALS
ALFPVLRSDFTAGETYTPPPDATVACDITALIGDKDVLAPLERVSSWREHTRANFDLQVFRGGGHFYLEDHIDEVSACLI
QVCNVSPII

Sequences:

>Translated_249_residues
MRRTDELLPGNPWLRRLRDGNGATRVICFPHAGGSASYFRRLAKMLPADTEVLAVQYPGRGNRLREQPIASVPLLAEGIA
SALPASDKQDVLFGHSLGGHIAFEVAQRLPVRKLVVSGIVAPSKVVDLGYRLLNEAEGIERIAALGGLPPEILDDPSALS
ALFPVLRSDFTAGETYTPPPDATVACDITALIGDKDVLAPLERVSSWREHTRANFDLQVFRGGGHFYLEDHIDEVSACLI
QVCNVSPII
>Mature_249_residues
MRRTDELLPGNPWLRRLRDGNGATRVICFPHAGGSASYFRRLAKMLPADTEVLAVQYPGRGNRLREQPIASVPLLAEGIA
SALPASDKQDVLFGHSLGGHIAFEVAQRLPVRKLVVSGIVAPSKVVDLGYRLLNEAEGIERIAALGGLPPEILDDPSALS
ALFPVLRSDFTAGETYTPPPDATVACDITALIGDKDVLAPLERVSSWREHTRANFDLQVFRGGGHFYLEDHIDEVSACLI
QVCNVSPII

Specific function: Probable thioesterase involved in the biosynthesis of candicidin. Could release the macrolide ring from the polyketide synthase [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=249, Percent_Identity=26.5060240963855, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI8922871, Length=213, Percent_Identity=26.7605633802817, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR010693
- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF06902 DUF1271; PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 26965; Mature: 26965

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTDELLPGNPWLRRLRDGNGATRVICFPHAGGSASYFRRLAKMLPADTEVLAVQYPGR
CCCCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCC
GNRLREQPIASVPLLAEGIASALPASDKQDVLFGHSLGGHIAFEVAQRLPVRKLVVSGIV
CCCHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHCCHHHHHHHHCC
APSKVVDLGYRLLNEAEGIERIAALGGLPPEILDDPSALSALFPVLRSDFTAGETYTPPP
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCC
DATVACDITALIGDKDVLAPLERVSSWREHTRANFDLQVFRGGGHFYLEDHIDEVSACLI
CCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEHHHHHHHHHHHH
QVCNVSPII
HHHCCCCCC
>Mature Secondary Structure
MRRTDELLPGNPWLRRLRDGNGATRVICFPHAGGSASYFRRLAKMLPADTEVLAVQYPGR
CCCCCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCC
GNRLREQPIASVPLLAEGIASALPASDKQDVLFGHSLGGHIAFEVAQRLPVRKLVVSGIV
CCCHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHCCHHHHHHHHCC
APSKVVDLGYRLLNEAEGIERIAALGGLPPEILDDPSALSALFPVLRSDFTAGETYTPPP
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCC
DATVACDITALIGDKDVLAPLERVSSWREHTRANFDLQVFRGGGHFYLEDHIDEVSACLI
CCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEHHHHHHHHHHHH
QVCNVSPII
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]