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The map label for this gene is murG [H]

Identifier: 169629093

GI number: 169629093

Start: 2005930

End: 2007078

Strand: Direct

Name: murG [H]

Synonym: MAB_2006

Alternate gene names: 169629093

Gene position: 2005930-2007078 (Clockwise)

Preceding gene: 169629092

Following gene: 169629094

Centisome position: 39.59

GC content: 68.32

Gene sequence:

>1149_bases
GTGAGTGATGAACTTCGGCCGCTTTCGGTGGTGCTGGCCGGTGGCGGCACCGCGGGACACGTCGAGCCGGCCATGGCGGT
TGCCGACGCGCTGCGCGAGATTGATCCCACGGTGCGGATCACCGCGCTGGGTACCGAGCGCGGCCTCGAGACGCGGCTGG
TTCCCGATCGTGGTTACCACCTGGAACTGATCGTTCCGGTGCCGCTGCCGCGTCGCCTCACCGGCGATCTGGTGCGGTTG
CCACTGCGGGTGCGCCGGGCGGTTCGGCAGACGCGCGCCGTGTTCGACGGCGTCCAGGCCGACGTCGTGATCGGTTTCGG
TGGCTACGTCGCCTTACCCGCCTATTTGGCGGCTCGCCGCGGTCCGTTGCGCCGCCGCCGCGTGCCGGTCGTCATCCACG
AGGCGAACGCCCGTGCCGGCCTTGCCAACCGGGTCGGAGCGCGCGGAGCGCAGCGGGTGTTATCGGCGGTCCCGGACTCG
GGCCTGCGTGATGCGGAGGTAGTGGGAGTGCCGGTTCGGGGGTCGATCACCGCCCTGGACCGCGCGGCCCTGCGGCACCA
GGCACGTGCTCACTACGGGTTTGATGACGATGCCCTGGTGCTATTGGTGTTCGGCGGTTCGCAGGGAGCGGTCTCCCTCA
ACAACGCGGTTTCCGCAGCGGCCAATGACCTTGCCGCCGCCGGTGTTTCGGTGTTGCATGCACATGGCCCAAAGAACACG
ATTAAATTGCCGGAGCGCCCGCCTGGCGCACCCAGATATGTTGCGTTGCCGTACCTGGACCGCATGGACCTGGCGTACGC
GGCCGCGGATATCGCGGTGTGCCGATCCGGTGCTATGACCGTCGCGGAGGTTTCGGCGGTGGGGCTGCCCGCCATCTACG
TGCCTCTACCGATCGGCAACGGTGAGCAGCGGCTCAACGCGTTACCGATTGTGGACGCCGGTGGAGGTGTCATCGTCGCG
GACCGCGACCTGACCCCTGAGTCATTGGCGCACATGGTGATTGAGATGGTGTCCGATCCCGCCAAGCTCGCCGCCATGAC
ATCGGCCGCGGCACTGTCCGGACACCCGGAAGCCGCTCGACAGGTGGCGCAGGTGGCGTTGGATGTCGCGCGTGAGCGGC
GTTCGCGGGAACGGGGTGGCCGTCGATGA

Upstream 100 bases:

>100_bases
GCAGGTCCCGTGATCAGTCACGGACCGCGGGCTCACGCGCCCGAAGCTACCGATAGCCGCTGACATGTGATCGCCGCCAG
ACCGAAAGGATGCTCCCGGA

Downstream 100 bases:

>100_bases
ACGCAGGTCCGCTGCCGGAGCATCTGCGCCGCGTGCACATGGTCGGTATCGGTGGTGCCGGAATGTCCGGTATCGCCCGC
ATTCTGCTGGATCGCGGCGC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MSDELRPLSVVLAGGGTAGHVEPAMAVADALREIDPTVRITALGTERGLETRLVPDRGYHLELIVPVPLPRRLTGDLVRL
PLRVRRAVRQTRAVFDGVQADVVIGFGGYVALPAYLAARRGPLRRRRVPVVIHEANARAGLANRVGARGAQRVLSAVPDS
GLRDAEVVGVPVRGSITALDRAALRHQARAHYGFDDDALVLLVFGGSQGAVSLNNAVSAAANDLAAAGVSVLHAHGPKNT
IKLPERPPGAPRYVALPYLDRMDLAYAAADIAVCRSGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPIVDAGGGVIVA
DRDLTPESLAHMVIEMVSDPAKLAAMTSAAALSGHPEAARQVAQVALDVARERRSRERGGRR

Sequences:

>Translated_382_residues
MSDELRPLSVVLAGGGTAGHVEPAMAVADALREIDPTVRITALGTERGLETRLVPDRGYHLELIVPVPLPRRLTGDLVRL
PLRVRRAVRQTRAVFDGVQADVVIGFGGYVALPAYLAARRGPLRRRRVPVVIHEANARAGLANRVGARGAQRVLSAVPDS
GLRDAEVVGVPVRGSITALDRAALRHQARAHYGFDDDALVLLVFGGSQGAVSLNNAVSAAANDLAAAGVSVLHAHGPKNT
IKLPERPPGAPRYVALPYLDRMDLAYAAADIAVCRSGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPIVDAGGGVIVA
DRDLTPESLAHMVIEMVSDPAKLAAMTSAAALSGHPEAARQVAQVALDVARERRSRERGGRR
>Mature_381_residues
SDELRPLSVVLAGGGTAGHVEPAMAVADALREIDPTVRITALGTERGLETRLVPDRGYHLELIVPVPLPRRLTGDLVRLP
LRVRRAVRQTRAVFDGVQADVVIGFGGYVALPAYLAARRGPLRRRRVPVVIHEANARAGLANRVGARGAQRVLSAVPDSG
LRDAEVVGVPVRGSITALDRAALRHQARAHYGFDDDALVLLVFGGSQGAVSLNNAVSAAANDLAAAGVSVLHAHGPKNTI
KLPERPPGAPRYVALPYLDRMDLAYAAADIAVCRSGAMTVAEVSAVGLPAIYVPLPIGNGEQRLNALPIVDAGGGVIVAD
RDLTPESLAHMVIEMVSDPAKLAAMTSAAALSGHPEAARQVAQVALDVARERRSRERGGRR

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=373, Percent_Identity=36.1930294906166, Blast_Score=181, Evalue=9e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 40139; Mature: 40008

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDELRPLSVVLAGGGTAGHVEPAMAVADALREIDPTVRITALGTERGLETRLVPDRGYH
CCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCCE
LELIVPVPLPRRLTGDLVRLPLRVRRAVRQTRAVFDGVQADVVIGFGGYVALPAYLAARR
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHC
GPLRRRRVPVVIHEANARAGLANRVGARGAQRVLSAVPDSGLRDAEVVGVPVRGSITALD
CCHHHCCCCEEEECCCCCCCHHHHHCHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHH
RAALRHQARAHYGFDDDALVLLVFGGSQGAVSLNNAVSAAANDLAAAGVSVLHAHGPKNT
HHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEECHHHHHHHHHHHHHCHHEEECCCCCCC
IKLPERPPGAPRYVALPYLDRMDLAYAAADIAVCRSGAMTVAEVSAVGLPAIYVPLPIGN
EECCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHCCCCEEEEEECCCC
GEQRLNALPIVDAGGGVIVADRDLTPESLAHMVIEMVSDPAKLAAMTSAAALSGHPEAAR
CHHHHCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
QVAQVALDVARERRSRERGGRR
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDELRPLSVVLAGGGTAGHVEPAMAVADALREIDPTVRITALGTERGLETRLVPDRGYH
CCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCCE
LELIVPVPLPRRLTGDLVRLPLRVRRAVRQTRAVFDGVQADVVIGFGGYVALPAYLAARR
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHC
GPLRRRRVPVVIHEANARAGLANRVGARGAQRVLSAVPDSGLRDAEVVGVPVRGSITALD
CCHHHCCCCEEEECCCCCCCHHHHHCHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHH
RAALRHQARAHYGFDDDALVLLVFGGSQGAVSLNNAVSAAANDLAAAGVSVLHAHGPKNT
HHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEECHHHHHHHHHHHHHCHHEEECCCCCCC
IKLPERPPGAPRYVALPYLDRMDLAYAAADIAVCRSGAMTVAEVSAVGLPAIYVPLPIGN
EECCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHCCCCEEEEEECCCC
GEQRLNALPIVDAGGGVIVADRDLTPESLAHMVIEMVSDPAKLAAMTSAAALSGHPEAAR
CHHHHCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
QVAQVALDVARERRSRERGGRR
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA