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The map label for this gene is ftsW [C]

Identifier: 169629092

GI number: 169629092

Start: 2004311

End: 2005885

Strand: Direct

Name: ftsW [C]

Synonym: MAB_2005

Alternate gene names: 169629092

Gene position: 2004311-2005885 (Clockwise)

Preceding gene: 169629091

Following gene: 169629093

Centisome position: 39.55

GC content: 66.48

Gene sequence:

>1575_bases
GTGTCCACCCTGACTGCTCCATTCGCCAGGATTTTCCGTTCCGAGAAGCGCGACGAAGCAAAGACCTCCGTCACGTCGGT
CAAGAAGTCCGGCGCCAAAAACGACGGGCTGATCGCGCGCACCCGCTTGGGTGCCTGGCTGAACCGGCCGATGACGTCGT
TTCACCTGGTGGTCGCGACGGCGGCGTTGCTCACCACGCTCGGCCTGATCATGGTGCTGTCCGCCTCGGGCGTCGAGTCG
TACTACGACGACGGGTCCGCGTGGACGATTTTCGGCAAGCAGGTGCTGTGGGTCTGCGTGGGTCTGGTCGGCTTCTACAT
CGCCCTGCGCACCCCGGTGGCGGTGATGCGCAGGTACTCGTTCCCCGTCTTCGTCTTCACGGTCATCTTGATCACCCTGG
TGCTCATTCCCGGAATCGGCACGTATTCCAACGGTTCTCGGGGGTGGTTCGTCTATGCCGGTCTGTCCATGCAGCCCTCC
GAGCTCACCAAGGTCGCGTTCGCGATTTGGGGAGCGCATCTGCTGGCCTCACGCCGCATGGAGCAGGCCAGCATGCGGGA
GATGCTGGTCCCGCTGGTACCCGCGGCGCTGATCGCGCTGGTGCTGATCGTCATCCAGCCCGACCTCGGGCAGACGGTTT
CCTTGAGCATCATCTTGTTGGCCCTGCTGTGGTACGCGGGTCTGCCGTTGAAGGTCTTTCTGAGTTCGGTGGTGGCGGCC
GTGCTGGCCGCGGCCATCCTGGCGGTATCGGCCGGGTACCGGTCCGACCGGGTCAAGGCGTGGCTGGACCCGTCCGCTGA
CCCGCAGGCGACCGGATATCAGTCGCGGCAGGCACGTTTCGCGCTCGCGCAGGGCGGTTTCTTCGGCCAGGGTCTGGGGC
AGGGATCGGCGAAATGGCATTACCTGCCGAACGCGCACAACGACTTCATCTTCGCCATCATCGGCGAGGAGCTCGGATTC
GTCGGCTGCATCGGAGTGCTCGCCCTGTTCGGTGTCTTCGCGTACACCGCGATGCGCATTGCCCGACGCAGCGCGGACCC
GTTCTTGCGCATGATCACCGCGACCGCCGGGCTGTGGATGATCGGCCAGTCCTTCATCAACATCGGATACGTCATCGGTC
TGCTGCCGGTGACGGGTATCCAGCTGCCGCTGATCTCTTCCGGCGGAACGTCGACGGCAACGGCGCTGTTCTTCATCGGT
TTGATAGCCAATGCGGCCCGCCACGAACCCGAGGCGGTGGCGGCCCTGCGCGCTGGTTCCGGCGACCGGATGAACAGGCT
GCTGCGGCTCCCACTGCCGGAGCCGTATGTGCCACCGCGGATCGACGCCGCGCGTGACCGCCTGCGCGCCAAGTCGGCAG
CGCAGAGCGCCGCAGCGGCCCGGCCGCAGCCCGAGCGCAAGCGACAGTCCGCGTCGGCGCCGGGGCCCAAGCGCACGCCG
CGTGCACGCACCGATAACGAAGCAGGGCATCATAGGCAGGTACAACAGGCGCGGCGAGGCTCCGCCACGCGCGCGAGCGG
CAGGTCCCGTGATCAGTCACGGACCGCGGGCTCACGCGCCCGAAGCTACCGATAG

Upstream 100 bases:

>100_bases
CTCCGGCAGGCGCGTCCTTCGACCAATTCAGCGGGTATTCCGAGCGTGGCGACCGGTTCGCCGCGGCGGTGCACGCACTT
ACCGGTTAGGTGATTGCGTC

Downstream 100 bases:

>100_bases
CCGCTGACATGTGATCGCCGCCAGACCGAAAGGATGCTCCCGGAGTGAGTGATGAACTTCGGCCGCTTTCGGTGGTGCTG
GCCGGTGGCGGCACCGCGGG

Product: putative cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 523

Protein sequence:

>524_residues
MSTLTAPFARIFRSEKRDEAKTSVTSVKKSGAKNDGLIARTRLGAWLNRPMTSFHLVVATAALLTTLGLIMVLSASGVES
YYDDGSAWTIFGKQVLWVCVGLVGFYIALRTPVAVMRRYSFPVFVFTVILITLVLIPGIGTYSNGSRGWFVYAGLSMQPS
ELTKVAFAIWGAHLLASRRMEQASMREMLVPLVPAALIALVLIVIQPDLGQTVSLSIILLALLWYAGLPLKVFLSSVVAA
VLAAAILAVSAGYRSDRVKAWLDPSADPQATGYQSRQARFALAQGGFFGQGLGQGSAKWHYLPNAHNDFIFAIIGEELGF
VGCIGVLALFGVFAYTAMRIARRSADPFLRMITATAGLWMIGQSFINIGYVIGLLPVTGIQLPLISSGGTSTATALFFIG
LIANAARHEPEAVAALRAGSGDRMNRLLRLPLPEPYVPPRIDAARDRLRAKSAAQSAAAARPQPERKRQSASAPGPKRTP
RARTDNEAGHHRQVQQARRGSATRASGRSRDQSRTAGSRARSYR

Sequences:

>Translated_524_residues
MSTLTAPFARIFRSEKRDEAKTSVTSVKKSGAKNDGLIARTRLGAWLNRPMTSFHLVVATAALLTTLGLIMVLSASGVES
YYDDGSAWTIFGKQVLWVCVGLVGFYIALRTPVAVMRRYSFPVFVFTVILITLVLIPGIGTYSNGSRGWFVYAGLSMQPS
ELTKVAFAIWGAHLLASRRMEQASMREMLVPLVPAALIALVLIVIQPDLGQTVSLSIILLALLWYAGLPLKVFLSSVVAA
VLAAAILAVSAGYRSDRVKAWLDPSADPQATGYQSRQARFALAQGGFFGQGLGQGSAKWHYLPNAHNDFIFAIIGEELGF
VGCIGVLALFGVFAYTAMRIARRSADPFLRMITATAGLWMIGQSFINIGYVIGLLPVTGIQLPLISSGGTSTATALFFIG
LIANAARHEPEAVAALRAGSGDRMNRLLRLPLPEPYVPPRIDAARDRLRAKSAAQSAAAARPQPERKRQSASAPGPKRTP
RARTDNEAGHHRQVQQARRGSATRASGRSRDQSRTAGSRARSYR
>Mature_523_residues
STLTAPFARIFRSEKRDEAKTSVTSVKKSGAKNDGLIARTRLGAWLNRPMTSFHLVVATAALLTTLGLIMVLSASGVESY
YDDGSAWTIFGKQVLWVCVGLVGFYIALRTPVAVMRRYSFPVFVFTVILITLVLIPGIGTYSNGSRGWFVYAGLSMQPSE
LTKVAFAIWGAHLLASRRMEQASMREMLVPLVPAALIALVLIVIQPDLGQTVSLSIILLALLWYAGLPLKVFLSSVVAAV
LAAAILAVSAGYRSDRVKAWLDPSADPQATGYQSRQARFALAQGGFFGQGLGQGSAKWHYLPNAHNDFIFAIIGEELGFV
GCIGVLALFGVFAYTAMRIARRSADPFLRMITATAGLWMIGQSFINIGYVIGLLPVTGIQLPLISSGGTSTATALFFIGL
IANAARHEPEAVAALRAGSGDRMNRLLRLPLPEPYVPPRIDAARDRLRAKSAAQSAAAARPQPERKRQSASAPGPKRTPR
ARTDNEAGHHRQVQQARRGSATRASGRSRDQSRTAGSRARSYR

Specific function: This Is A Septum-Peptidoglycan Biosynthetic Protein, Involved In Cell Wall Formation. Plays A Role In The Stabilization Of The Ftsz Ring During Cell Division. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=355, Percent_Identity=35.7746478873239, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1786853, Length=291, Percent_Identity=31.6151202749141, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 56513; Mature: 56382

Theoretical pI: Translated: 11.47; Mature: 11.47

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLTAPFARIFRSEKRDEAKTSVTSVKKSGAKNDGLIARTRLGAWLNRPMTSFHLVVAT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
AALLTTLGLIMVLSASGVESYYDDGSAWTIFGKQVLWVCVGLVGFYIALRTPVAVMRRYS
HHHHHHHHHHHHHHHCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FPVFVFTVILITLVLIPGIGTYSNGSRGWFVYAGLSMQPSELTKVAFAIWGAHLLASRRM
CHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
EQASMREMLVPLVPAALIALVLIVIQPDLGQTVSLSIILLALLWYAGLPLKVFLSSVVAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VLAAAILAVSAGYRSDRVKAWLDPSADPQATGYQSRQARFALAQGGFFGQGLGQGSAKWH
HHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEE
YLPNAHNDFIFAIIGEELGFVGCIGVLALFGVFAYTAMRIARRSADPFLRMITATAGLWM
ECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IGQSFINIGYVIGLLPVTGIQLPLISSGGTSTATALFFIGLIANAARHEPEAVAALRAGS
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
GDRMNRLLRLPLPEPYVPPRIDAARDRLRAKSAAQSAAAARPQPERKRQSASAPGPKRTP
CHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCC
RARTDNEAGHHRQVQQARRGSATRASGRSRDQSRTAGSRARSYR
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
STLTAPFARIFRSEKRDEAKTSVTSVKKSGAKNDGLIARTRLGAWLNRPMTSFHLVVAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
AALLTTLGLIMVLSASGVESYYDDGSAWTIFGKQVLWVCVGLVGFYIALRTPVAVMRRYS
HHHHHHHHHHHHHHHCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FPVFVFTVILITLVLIPGIGTYSNGSRGWFVYAGLSMQPSELTKVAFAIWGAHLLASRRM
CHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
EQASMREMLVPLVPAALIALVLIVIQPDLGQTVSLSIILLALLWYAGLPLKVFLSSVVAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VLAAAILAVSAGYRSDRVKAWLDPSADPQATGYQSRQARFALAQGGFFGQGLGQGSAKWH
HHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEE
YLPNAHNDFIFAIIGEELGFVGCIGVLALFGVFAYTAMRIARRSADPFLRMITATAGLWM
ECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IGQSFINIGYVIGLLPVTGIQLPLISSGGTSTATALFFIGLIANAARHEPEAVAALRAGS
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
GDRMNRLLRLPLPEPYVPPRIDAARDRLRAKSAAQSAAAARPQPERKRQSASAPGPKRTP
CHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCC
RARTDNEAGHHRQVQQARRGSATRASGRSRDQSRTAGSRARSYR
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]