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The map label for this gene is lipB [H]

Identifier: 169629030

GI number: 169629030

Start: 1941655

End: 1942347

Strand: Reverse

Name: lipB [H]

Synonym: MAB_1943c

Alternate gene names: 169629030

Gene position: 1942347-1941655 (Counterclockwise)

Preceding gene: 169629031

Following gene: 169629029

Centisome position: 38.33

GC content: 67.24

Gene sequence:

>693_bases
ATGGAACCCGTGCACCGCTCCCATGGATCCATCCGGTCCAGCGCAGCCCCCGTCGAGGTACGGGATCTGGGCGTGATCGA
CTACGAGATGGCATGGGAGCTGCAGCGTGACATCGTCGAAGCACGGGTCGCCGGCGGACCCGACACCCTGCTGACCTTGC
AGCACCCCGCCGTCTACACCGCGGGGCGGCGTACCGAACCGCAGGAGCGGCCCATCAACGGCGCGCCCGTCATCGACACC
GACCGTGGCGGCAAGATCACGTGGCACGGACCCGGCCAGCTGGTCGGCTACCCGATAGTGCAGCTCGCCGAGCCCATCGA
CGTGGTGAACTATGTTCGCCGCGTTGAGGAATCGATCATCGCGGTCTGCGCGCAACTGGGCGTGCAGACCAAGCGTGTCG
AGGGCCGCTCGGGTGTGTGGCTGGCCGCGGGCGGCGGCAAGCCGGAACGCAAGATCGCCGCGATCGGCGTACGCGTGCAG
CGCGGCGTCACCATGCACGGGTTCTCGCTGAACTGCAATAACAGTCTCGATGCCTACCTGCCCATCGTGGCGTGTGGCAT
CACCGATGCCGGAGTGACGACCCTGTCCGCCGAGCTGGGCCGCGACGTCACCGTCGATGAGGTGCACGACCAGGTTGTTT
CCTCGGTTTTGGACGCGCTCGAAGGCCGGCTTCCCGTCGGAGCGACGGCATGA

Upstream 100 bases:

>100_bases
ATCCCCGCCGTGTTGGAACAGCACGGATTCGAATTCGAGCACCACACCATCGGCGAGGCGCTGGCCTACGCCAACAACAG
TCGACCGATGAAGTGAGATA

Downstream 100 bases:

>100_bases
CAGAACCCCGCAAGCTACTGCGGCTGGAAGTCCGCAACGCCCAAACCCCGATCGAGCGCAAGCCGGACTGGATTCGCACC
CGCGCGAAGATGGGCCCCGA

Product: lipoate-protein ligase B

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MEPVHRSHGSIRSSAAPVEVRDLGVIDYEMAWELQRDIVEARVAGGPDTLLTLQHPAVYTAGRRTEPQERPINGAPVIDT
DRGGKITWHGPGQLVGYPIVQLAEPIDVVNYVRRVEESIIAVCAQLGVQTKRVEGRSGVWLAAGGGKPERKIAAIGVRVQ
RGVTMHGFSLNCNNSLDAYLPIVACGITDAGVTTLSAELGRDVTVDEVHDQVVSSVLDALEGRLPVGATA

Sequences:

>Translated_230_residues
MEPVHRSHGSIRSSAAPVEVRDLGVIDYEMAWELQRDIVEARVAGGPDTLLTLQHPAVYTAGRRTEPQERPINGAPVIDT
DRGGKITWHGPGQLVGYPIVQLAEPIDVVNYVRRVEESIIAVCAQLGVQTKRVEGRSGVWLAAGGGKPERKIAAIGVRVQ
RGVTMHGFSLNCNNSLDAYLPIVACGITDAGVTTLSAELGRDVTVDEVHDQVVSSVLDALEGRLPVGATA
>Mature_230_residues
MEPVHRSHGSIRSSAAPVEVRDLGVIDYEMAWELQRDIVEARVAGGPDTLLTLQHPAVYTAGRRTEPQERPINGAPVIDT
DRGGKITWHGPGQLVGYPIVQLAEPIDVVNYVRRVEESIIAVCAQLGVQTKRVEGRSGVWLAAGGGKPERKIAAIGVRVQ
RGVTMHGFSLNCNNSLDAYLPIVACGITDAGVTTLSAELGRDVTVDEVHDQVVSSVLDALEGRLPVGATA

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG0321

COG function: function code H; Lipoate-protein ligase B

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipB family [H]

Homologues:

Organism=Homo sapiens, GI221554520, Length=168, Percent_Identity=42.2619047619048, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI87081767, Length=205, Percent_Identity=28.2926829268293, Blast_Score=95, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21355483, Length=211, Percent_Identity=35.5450236966825, Blast_Score=120, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 24553; Mature: 24553

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS01313 LIPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPVHRSHGSIRSSAAPVEVRDLGVIDYEMAWELQRDIVEARVAGGPDTLLTLQHPAVYT
CCCCCCCCCCCCCCCCCEEEHHCCEECHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEE
AGRRTEPQERPINGAPVIDTDRGGKITWHGPGQLVGYPIVQLAEPIDVVNYVRRVEESII
CCCCCCCCCCCCCCCCEEECCCCCEEEECCCCCEECCCHHHHHCHHHHHHHHHHHHHHHH
AVCAQLGVQTKRVEGRSGVWLAAGGGKPERKIAAIGVRVQRGVTMHGFSLNCNNSLDAYL
HHHHHHCCCEEEECCCCCEEEEECCCCCCCEEEEEEEEEECCCEEEEEEECCCCCCHHEE
PIVACGITDAGVTTLSAELGRDVTVDEVHDQVVSSVLDALEGRLPVGATA
HEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MEPVHRSHGSIRSSAAPVEVRDLGVIDYEMAWELQRDIVEARVAGGPDTLLTLQHPAVYT
CCCCCCCCCCCCCCCCCEEEHHCCEECHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEE
AGRRTEPQERPINGAPVIDTDRGGKITWHGPGQLVGYPIVQLAEPIDVVNYVRRVEESII
CCCCCCCCCCCCCCCCEEECCCCCEEEECCCCCEECCCHHHHHCHHHHHHHHHHHHHHHH
AVCAQLGVQTKRVEGRSGVWLAAGGGKPERKIAAIGVRVQRGVTMHGFSLNCNNSLDAYL
HHHHHHCCCEEEECCCCCEEEEECCCCCCCEEEEEEEEEECCCEEEEEEECCCCCCHHEE
PIVACGITDAGVTTLSAELGRDVTVDEVHDQVVSSVLDALEGRLPVGATA
HEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA