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The map label for this gene is murA [H]

Identifier: 169628548

GI number: 169628548

Start: 1460413

End: 1461651

Strand: Direct

Name: murA [H]

Synonym: MAB_1457

Alternate gene names: 169628548

Gene position: 1460413-1461651 (Clockwise)

Preceding gene: 169628546

Following gene: 169628549

Centisome position: 28.82

GC content: 62.95

Gene sequence:

>1239_bases
TTGGTAACCGGCGGCGCCCGGCTGACAGGCAACGTGGCAGTGACCGGCGCCAAGAACAGCGTGCTCAAGCTGATGGCGGC
AGCTCTTCTAGCCGAGGGGACCAGCACCATCACCAACTGTCCGGACATCCTGGACGTGCCGCTCATGGCTGAGGTGCTGC
GCGGATTGGGCGCGACGGTCGAGTTGGAAGGCGATGTAGTCAGGATCACTTCGCCCGACGAGCCGAAGTATGACGCGGAC
TTCGCCGCAGTCAGGCAGTTCCGTGCCTCGGTCTGTGTCCTCGGACCTCTGGTGGGCCGATGCCGGAGGGCCAAGGTCGC
GCTACCTGGCGGGGATGCGATCGGATCACGACCGCTTGATATGCATCAGGCGGGGCTGCGGCAGCTCGGCGCGGAGTGCA
CCATTGAGCACGGCTGCGTGGTTGCGGAGGCAAAAGCCTTACACGGAGCCGATATTCATCTTGAGTTTCCGTCGGTGGGC
GCCACCGAGAACATCTTGATGGCAGCGGTGCTCGCTGACGGCGTGACGACCATCCACAACGCGGCACGTGAACCCGACGT
GGTCGACCTGTGCACCATGCTGGTGCAGATGGGGGCCGAGATCGAGGGAGCGGGAACGTCGACGCTGACAGTAACCGGTG
TTTCCGCGCTTCATCCCACCGAGCATCGCGTCATTGGAGACCGAATCGTCGCTGCCACTTGGGGTCTCGCTGCGGCGATG
ACGCGCGGCGATGTCACGGTCACGGGCGTGGATCCGGAGCACTTGCAGTTGGTACTGCACAAGTTGCACGATGCTGGGGC
GACAGTCACGCAGAGCGACGACGGTTTCCGTGTCGTGCAGTACGAGCGCCCGAAGGCGATCAACGTCGCCACGCTGCCGT
TCCCAGGATTCCCAACTGACTTGCAGCCCATGGCAATTGGGCTAGCGGCCATAGCTGACGGCACATCCATGATCACCGAA
AACGTCTTCGAGGCCCGCTTCCGTTTTGTCGAAGAGATGATGCGTTTAGGGGCCGACGCGCGAACCGATGGGCATCACGC
AGTGGTTCGGGGTATCCGGCAACTGTCCAGCGCTCCGGTGTGGTCGTCGGATATTCGGGCCGGCGCGGGTCTGGTACTGG
CGGGTCTAGTGGCGGACGGCGTCACAGAGGTATACGATGTGTTTCATATCGACCGCGGTTACCCGTTGTTCGTGGAGAAT
CTCCAGAGCTTGGGTGCCGAAGTCGAGCGGGTCAGCTAG

Upstream 100 bases:

>100_bases
CGGCTCGCTCTGATCGGGGGTTCGTCCCGCCGGTGGATGCCTCATCGGTCATGCGTCGTGACGTTACCCGGCTACGCTGT
CGGGCGTGAGCGAGCATTTC

Downstream 100 bases:

>100_bases
CGCTGACCAAGCCCCCGACCCGAAGTTGACTCAAGTTCATTGGACTTGGTACAGTGGTCGGGTTGCCCTGAAAGAGCGAG
ACCGGGACGAGGAAGCGATT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MVTGGARLTGNVAVTGAKNSVLKLMAAALLAEGTSTITNCPDILDVPLMAEVLRGLGATVELEGDVVRITSPDEPKYDAD
FAAVRQFRASVCVLGPLVGRCRRAKVALPGGDAIGSRPLDMHQAGLRQLGAECTIEHGCVVAEAKALHGADIHLEFPSVG
ATENILMAAVLADGVTTIHNAAREPDVVDLCTMLVQMGAEIEGAGTSTLTVTGVSALHPTEHRVIGDRIVAATWGLAAAM
TRGDVTVTGVDPEHLQLVLHKLHDAGATVTQSDDGFRVVQYERPKAINVATLPFPGFPTDLQPMAIGLAAIADGTSMITE
NVFEARFRFVEEMMRLGADARTDGHHAVVRGIRQLSSAPVWSSDIRAGAGLVLAGLVADGVTEVYDVFHIDRGYPLFVEN
LQSLGAEVERVS

Sequences:

>Translated_412_residues
MVTGGARLTGNVAVTGAKNSVLKLMAAALLAEGTSTITNCPDILDVPLMAEVLRGLGATVELEGDVVRITSPDEPKYDAD
FAAVRQFRASVCVLGPLVGRCRRAKVALPGGDAIGSRPLDMHQAGLRQLGAECTIEHGCVVAEAKALHGADIHLEFPSVG
ATENILMAAVLADGVTTIHNAAREPDVVDLCTMLVQMGAEIEGAGTSTLTVTGVSALHPTEHRVIGDRIVAATWGLAAAM
TRGDVTVTGVDPEHLQLVLHKLHDAGATVTQSDDGFRVVQYERPKAINVATLPFPGFPTDLQPMAIGLAAIADGTSMITE
NVFEARFRFVEEMMRLGADARTDGHHAVVRGIRQLSSAPVWSSDIRAGAGLVLAGLVADGVTEVYDVFHIDRGYPLFVEN
LQSLGAEVERVS
>Mature_412_residues
MVTGGARLTGNVAVTGAKNSVLKLMAAALLAEGTSTITNCPDILDVPLMAEVLRGLGATVELEGDVVRITSPDEPKYDAD
FAAVRQFRASVCVLGPLVGRCRRAKVALPGGDAIGSRPLDMHQAGLRQLGAECTIEHGCVVAEAKALHGADIHLEFPSVG
ATENILMAAVLADGVTTIHNAAREPDVVDLCTMLVQMGAEIEGAGTSTLTVTGVSALHPTEHRVIGDRIVAATWGLAAAM
TRGDVTVTGVDPEHLQLVLHKLHDAGATVTQSDDGFRVVQYERPKAINVATLPFPGFPTDLQPMAIGLAAIADGTSMITE
NVFEARFRFVEEMMRLGADARTDGHHAVVRGIRQLSSAPVWSSDIRAGAGLVLAGLVADGVTEVYDVFHIDRGYPLFVEN
LQSLGAEVERVS

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=413, Percent_Identity=44.3099273607748, Blast_Score=319, Evalue=2e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020683
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 43300; Mature: 43300

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50297 ANK_REP_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTGGARLTGNVAVTGAKNSVLKLMAAALLAEGTSTITNCPDILDVPLMAEVLRGLGATV
CCCCCCEEECCEEEECCCHHHHHHHHHHHHHCCCCHHCCCCCHHCHHHHHHHHHHCCCEE
ELEGDVVRITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCRRAKVALPGGDAIGSRPLD
EECCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCCH
MHQAGLRQLGAECTIEHGCVVAEAKALHGADIHLEFPSVGATENILMAAVLADGVTTIHN
HHHHHHHHCCCCCEECCCEEEEEHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHH
AAREPDVVDLCTMLVQMGAEIEGAGTSTLTVTGVSALHPTEHRVIGDRIVAATWGLAAAM
HCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCHHCCCCHHHHHHHHHHHHHHHHHHHH
TRGDVTVTGVDPEHLQLVLHKLHDAGATVTQSDDGFRVVQYERPKAINVATLPFPGFPTD
CCCCEEEECCCHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCCEEEEEECCCCCCCCC
LQPMAIGLAAIADGTSMITENVFEARFRFVEEMMRLGADARTDGHHAVVRGIRQLSSAPV
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCC
WSSDIRAGAGLVLAGLVADGVTEVYDVFHIDRGYPLFVENLQSLGAEVERVS
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MVTGGARLTGNVAVTGAKNSVLKLMAAALLAEGTSTITNCPDILDVPLMAEVLRGLGATV
CCCCCCEEECCEEEECCCHHHHHHHHHHHHHCCCCHHCCCCCHHCHHHHHHHHHHCCCEE
ELEGDVVRITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCRRAKVALPGGDAIGSRPLD
EECCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCCH
MHQAGLRQLGAECTIEHGCVVAEAKALHGADIHLEFPSVGATENILMAAVLADGVTTIHN
HHHHHHHHCCCCCEECCCEEEEEHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHH
AAREPDVVDLCTMLVQMGAEIEGAGTSTLTVTGVSALHPTEHRVIGDRIVAATWGLAAAM
HCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCHHCCCCHHHHHHHHHHHHHHHHHHHH
TRGDVTVTGVDPEHLQLVLHKLHDAGATVTQSDDGFRVVQYERPKAINVATLPFPGFPTD
CCCCEEEECCCHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCCEEEEEECCCCCCCCC
LQPMAIGLAAIADGTSMITENVFEARFRFVEEMMRLGADARTDGHHAVVRGIRQLSSAPV
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCC
WSSDIRAGAGLVLAGLVADGVTEVYDVFHIDRGYPLFVENLQSLGAEVERVS
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371439 [H]