Click here to switch to the map view.

The map label for this gene is malE [C]

Identifier: 169628463

GI number: 169628463

Start: 1369306

End: 1370730

Strand: Direct

Name: malE [C]

Synonym: MAB_1372

Alternate gene names: 169628463

Gene position: 1369306-1370730 (Clockwise)

Preceding gene: 169628462

Following gene: 169628464

Centisome position: 27.02

GC content: 66.6

Gene sequence:

>1425_bases
GTGCTGGAGTCGTCGGCCAGATGGTTCCGACGCAAGGGTGTGGCGCTGGGCTCGTCCCTGCTGACCTGCCTGACGCTGGC
TTCGCTGACCGGATGTGCCCGCTCCGACGACCAGATCGTGATCCGCTTCTATACTCCGGCCAGCGAGGCGGGGACGTTCT
CCGCCGCCGCACAGCGATGCAATAGGGAGCTGGGCGGCCGGTTCACCATTCTGCAGGTCAGTCTGCCGAAACGCGCCGAC
GAGCAGCGGTTGCAGCTCGCGCGCCGGCTGACCGGCAACGACCGGACCCTGGACCTGATGGGGATGGACGTGGTGTGGAC
CGCCGAGTTCGCCGAAGCTGGTTGGGCGCTACCGCTTTCCGACGACCCAGCGGGTGTGACCGAGGCCGCCGCGCAGCGTG
ACGCCCTCGCGGGACCGCTGGAGAGCGCCCGGTGGAAGGGCAAGCTGTACGCCGCCCCGTTGAGCACCAATACTCAGCTG
CTTTGGTACCGCAAGGATCTGGTTCCCGAACCGCCCGCTACATGGGATCAGACGGTGCGCGAGGCGGAGAATTTCGCGCG
GTCTGAGGGTCCCAGCTGGATTGCTCTGCAGGGCAAGCAGTATGAGGGTCTGGTGGTTCTGTTCAACACACTGCTGTCCA
GCGCGGGCGGCTCCGTTCTGGCCGGTGACGGTAAGACCGTTACGTTGACGGACACCCCGGCGCACCGGCAGGCCACGGTC
ACTGCCTTGCGGACCATGAAATCGATCGCGACAGCCGATGGGGCCGATCCCTCGATCACGCAGACCGACGAGGGCACAGC
ACGTTTGGCATTCGAGCAGGGCAAGGCGGCATTCGAGATCAATTGGCCATTTGTGATGGCCAGCATGATGGAGAACGCCA
TCAAGGGTGGCGTCCCGTTCTTGCGACTGGACCGGCGGCCGGACCTGACCGGCGCGATCGGCGATGCGGGCCGATTCGCG
CCGAGCGAGGAGCAGTTCGCGGCGGCGTACGAGGCTGCCAGCGCGGCGCTCGGTTTCGCGCCATTTCCCTCCGTGGTGGC
CGGCCAGCCGGCCCGGGTCACCATTGGCGGGCTGAACATCGCGGTCGCCAAGACAACGCGATACAAGGCGCAGGCCTTCG
AGGCGCTGAACTGTCTGCGCAGCCGGGAGAACCAGAAGGCGACAGCCATCGAGGGCGGCTTGCCGGCGGTCGACTCGTCT
CTGTACGACGATCCGGAGTTCCAGGCGAAATATCCGGCGTACGCGATCATTCGCGACCAACTGGCCAACGCCGCGGTGCG
TCCCGCCTCGCCCTACTATCAAGCCATCTCGACGCGGGTCTCCGCCGTGTTGGCGCCGATCACCGGTATCGATCCCGAGC
GCACGGCGGACCTGCTGAACGATCAGGTGCAGAAGGCCGTCGACGGGCGGGGGCTGATCCCGTGA

Upstream 100 bases:

>100_bases
TCACCTGGTTTTCGCTCTACGGTTGCCGCGCGGGACGGGTGTACCCGCCGTGTGGGCACGCGGAGGTGCTTGAGACACGT
CAACGGACCAGGAGGCGGTC

Downstream 100 bases:

>100_bases
CCGACAGGACAAGCTCCGAGGGCAAGAGGGCCGAACGCCGGCTGGGGCTGCTACTCATCGCGCCGGCAGCGCTGCTGATG
TTGGCGGTCACCGCATATCC

Product: sugar ABC transporter, sugar-binding protein LpqY

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MLESSARWFRRKGVALGSSLLTCLTLASLTGCARSDDQIVIRFYTPASEAGTFSAAAQRCNRELGGRFTILQVSLPKRAD
EQRLQLARRLTGNDRTLDLMGMDVVWTAEFAEAGWALPLSDDPAGVTEAAAQRDALAGPLESARWKGKLYAAPLSTNTQL
LWYRKDLVPEPPATWDQTVREAENFARSEGPSWIALQGKQYEGLVVLFNTLLSSAGGSVLAGDGKTVTLTDTPAHRQATV
TALRTMKSIATADGADPSITQTDEGTARLAFEQGKAAFEINWPFVMASMMENAIKGGVPFLRLDRRPDLTGAIGDAGRFA
PSEEQFAAAYEAASAALGFAPFPSVVAGQPARVTIGGLNIAVAKTTRYKAQAFEALNCLRSRENQKATAIEGGLPAVDSS
LYDDPEFQAKYPAYAIIRDQLANAAVRPASPYYQAISTRVSAVLAPITGIDPERTADLLNDQVQKAVDGRGLIP

Sequences:

>Translated_474_residues
MLESSARWFRRKGVALGSSLLTCLTLASLTGCARSDDQIVIRFYTPASEAGTFSAAAQRCNRELGGRFTILQVSLPKRAD
EQRLQLARRLTGNDRTLDLMGMDVVWTAEFAEAGWALPLSDDPAGVTEAAAQRDALAGPLESARWKGKLYAAPLSTNTQL
LWYRKDLVPEPPATWDQTVREAENFARSEGPSWIALQGKQYEGLVVLFNTLLSSAGGSVLAGDGKTVTLTDTPAHRQATV
TALRTMKSIATADGADPSITQTDEGTARLAFEQGKAAFEINWPFVMASMMENAIKGGVPFLRLDRRPDLTGAIGDAGRFA
PSEEQFAAAYEAASAALGFAPFPSVVAGQPARVTIGGLNIAVAKTTRYKAQAFEALNCLRSRENQKATAIEGGLPAVDSS
LYDDPEFQAKYPAYAIIRDQLANAAVRPASPYYQAISTRVSAVLAPITGIDPERTADLLNDQVQKAVDGRGLIP
>Mature_474_residues
MLESSARWFRRKGVALGSSLLTCLTLASLTGCARSDDQIVIRFYTPASEAGTFSAAAQRCNRELGGRFTILQVSLPKRAD
EQRLQLARRLTGNDRTLDLMGMDVVWTAEFAEAGWALPLSDDPAGVTEAAAQRDALAGPLESARWKGKLYAAPLSTNTQL
LWYRKDLVPEPPATWDQTVREAENFARSEGPSWIALQGKQYEGLVVLFNTLLSSAGGSVLAGDGKTVTLTDTPAHRQATV
TALRTMKSIATADGADPSITQTDEGTARLAFEQGKAAFEINWPFVMASMMENAIKGGVPFLRLDRRPDLTGAIGDAGRFA
PSEEQFAAAYEAASAALGFAPFPSVVAGQPARVTIGGLNIAVAKTTRYKAQAFEALNCLRSRENQKATAIEGGLPAVDSS
LYDDPEFQAKYPAYAIIRDQLANAAVRPASPYYQAISTRVSAVLAPITGIDPERTADLLNDQVQKAVDGRGLIP

Specific function: Probably part of a binding-protein-dependent transport system [H]

COG id: COG1653

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 720 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 50833; Mature: 50833

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLESSARWFRRKGVALGSSLLTCLTLASLTGCARSDDQIVIRFYTPASEAGTFSAAAQRC
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHH
NRELGGRFTILQVSLPKRADEQRLQLARRLTGNDRTLDLMGMDVVWTAEFAEAGWALPLS
HHHHCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCEEEEEHHHHCCCCCCCC
DDPAGVTEAAAQRDALAGPLESARWKGKLYAAPLSTNTQLLWYRKDLVPEPPATWDQTVR
CCCCCHHHHHHHHHHHCCCHHHHCCCCEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHH
EAENFARSEGPSWIALQGKQYEGLVVLFNTLLSSAGGSVLAGDGKTVTLTDTPAHRQATV
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEECCCCEEEEECCCCCHHHHH
TALRTMKSIATADGADPSITQTDEGTARLAFEQGKAAFEINWPFVMASMMENAIKGGVPF
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCEEEEECCHHHHHHHHHHHHHCCCCE
LRLDRRPDLTGAIGDAGRFAPSEEQFAAAYEAASAALGFAPFPSVVAGQPARVTIGGLNI
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEEECCEE
AVAKTTRYKAQAFEALNCLRSRENQKATAIEGGLPAVDSSLYDDPEFQAKYPAYAIIRDQ
EEEECHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LANAAVRPASPYYQAISTRVSAVLAPITGIDPERTADLLNDQVQKAVDGRGLIP
HHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLESSARWFRRKGVALGSSLLTCLTLASLTGCARSDDQIVIRFYTPASEAGTFSAAAQRC
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHH
NRELGGRFTILQVSLPKRADEQRLQLARRLTGNDRTLDLMGMDVVWTAEFAEAGWALPLS
HHHHCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCEEEEEHHHHCCCCCCCC
DDPAGVTEAAAQRDALAGPLESARWKGKLYAAPLSTNTQLLWYRKDLVPEPPATWDQTVR
CCCCCHHHHHHHHHHHCCCHHHHCCCCEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHH
EAENFARSEGPSWIALQGKQYEGLVVLFNTLLSSAGGSVLAGDGKTVTLTDTPAHRQATV
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEECCCCEEEEECCCCCHHHHH
TALRTMKSIATADGADPSITQTDEGTARLAFEQGKAAFEINWPFVMASMMENAIKGGVPF
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCEEEEECCHHHHHHHHHHHHHCCCCE
LRLDRRPDLTGAIGDAGRFAPSEEQFAAAYEAASAALGFAPFPSVVAGQPARVTIGGLNI
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEEECCEE
AVAKTTRYKAQAFEALNCLRSRENQKATAIEGGLPAVDSSLYDDPEFQAKYPAYAIIRDQ
EEEECHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LANAAVRPASPYYQAISTRVSAVLAPITGIDPERTADLLNDQVQKAVDGRGLIP
HHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]