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The map label for this gene is moaB [H]

Identifier: 169628174

GI number: 169628174

Start: 1093298

End: 1093834

Strand: Direct

Name: moaB [H]

Synonym: MAB_1079

Alternate gene names: 169628174

Gene position: 1093298-1093834 (Clockwise)

Preceding gene: 169628173

Following gene: 169628175

Centisome position: 21.58

GC content: 64.43

Gene sequence:

>537_bases
ATGACCTCCATGTCCCCGCGAACGGTTACGGTTGCTTCCATGGCAGAGCTTGAGGCAGGACCGGTTGGGCGATCTCTGGT
CGTCATCGTCAACGACAGGACAGCCCACGGTGACCAGGACACTAGTGGTCCGCTCGTCACCGAGCTGCTCGCCGAGGCCG
GGTTTGTGGTCGACGGTGTGGTGGTTGTCGAAAATGACCTGTCGGAGATTCAAAACGCGGTGAACACCGCGGTCATCGGT
GGAGTGGACCTGGTGGTGACCGTCGGAGGCACCGGCGTCACTCCGCGTGATGTCGCACCCGAGGCGACACAGCCCCTGCT
CGATCGTGAGCTGCTGGGCATCGCCGAGGCGATCCGGTCGTCCGGGCTCGCGGCGGGCGTCACCGAGGCGGGCCTTTCGC
GCGGTGTCGCGGGCATTTCGGGTAGCACGCTGGTGGTCAACATCGCCGGTTCGCGTGCAGCGGTGCGTGACGGCATGGCC
ACGCTGACGCCCATGGCGATTCAGATCATCGAGCAGCTATCTAGTCTGGAGATCTGA

Upstream 100 bases:

>100_bases
TGCGGTCCAAAGCGCCCGGCGACAAGGTGACATTGACGTATACCGATGGCAACGGCGGCCAGGAGAAGACCGCCGACGTG
ACACTGGGTGAGGTCGCCCG

Downstream 100 bases:

>100_bases
CCGGGTGTCACCTCGGGATAGCCGAGATTGTGACCTTCGCCACAAAAATGGTGAAGGTGGAACAACTGCCAGCAATGCGG
ACATCGACCGGATCTTCGGT

Product: putative molybdopterin biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MTSMSPRTVTVASMAELEAGPVGRSLVVIVNDRTAHGDQDTSGPLVTELLAEAGFVVDGVVVVENDLSEIQNAVNTAVIG
GVDLVVTVGGTGVTPRDVAPEATQPLLDRELLGIAEAIRSSGLAAGVTEAGLSRGVAGISGSTLVVNIAGSRAAVRDGMA
TLTPMAIQIIEQLSSLEI

Sequences:

>Translated_178_residues
MTSMSPRTVTVASMAELEAGPVGRSLVVIVNDRTAHGDQDTSGPLVTELLAEAGFVVDGVVVVENDLSEIQNAVNTAVIG
GVDLVVTVGGTGVTPRDVAPEATQPLLDRELLGIAEAIRSSGLAAGVTEAGLSRGVAGISGSTLVVNIAGSRAAVRDGMA
TLTPMAIQIIEQLSSLEI
>Mature_177_residues
TSMSPRTVTVASMAELEAGPVGRSLVVIVNDRTAHGDQDTSGPLVTELLAEAGFVVDGVVVVENDLSEIQNAVNTAVIGG
VDLVVTVGGTGVTPRDVAPEATQPLLDRELLGIAEAIRSSGLAAGVTEAGLSRGVAGISGSTLVVNIAGSRAAVRDGMAT
LTPMAIQIIEQLSSLEI

Specific function: Maybe involved in the biosynthesis of molybdopterin [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=140, Percent_Identity=32.1428571428571, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI66932975, Length=140, Percent_Identity=32.1428571428571, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1787000, Length=135, Percent_Identity=37.7777777777778, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564954, Length=149, Percent_Identity=37.5838926174497, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17136978, Length=147, Percent_Identity=35.3741496598639, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24638841, Length=147, Percent_Identity=35.3741496598639, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 17956; Mature: 17824

Theoretical pI: Translated: 4.00; Mature: 4.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSMSPRTVTVASMAELEAGPVGRSLVVIVNDRTAHGDQDTSGPLVTELLAEAGFVVDGV
CCCCCCCEEEHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCEEECE
VVVENDLSEIQNAVNTAVIGGVDLVVTVGGTGVTPRDVAPEATQPLLDRELLGIAEAIRS
EEEECCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SGLAAGVTEAGLSRGVAGISGSTLVVNIAGSRAAVRDGMATLTPMAIQIIEQLSSLEI
CCCCCCHHHHHHHCCCCCCCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSMSPRTVTVASMAELEAGPVGRSLVVIVNDRTAHGDQDTSGPLVTELLAEAGFVVDGV
CCCCCCEEEHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCEEECE
VVVENDLSEIQNAVNTAVIGGVDLVVTVGGTGVTPRDVAPEATQPLLDRELLGIAEAIRS
EEEECCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SGLAAGVTEAGLSRGVAGISGSTLVVNIAGSRAAVRDGMATLTPMAIQIIEQLSSLEI
CCCCCCHHHHHHHCCCCCCCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]