Click here to switch to the map view.

The map label for this gene is crt [H]

Identifier: 169628002

GI number: 169628002

Start: 896503

End: 897243

Strand: Direct

Name: crt [H]

Synonym: MAB_0903

Alternate gene names: 169628002

Gene position: 896503-897243 (Clockwise)

Preceding gene: 169628001

Following gene: 169628003

Centisome position: 17.69

GC content: 65.59

Gene sequence:

>741_bases
GTGACCGAATATCAAACATTGTGTGTCACCACAGAAGACGACCGGGTGATCGTTGAGCTGCATCGTCCCGAGCAGCGCAA
CGCGATCAATGCCGCGATGGTCGCCGACCTGCACGCCGTCTGCGCGACTATCGAGGCGCAGCCCCGCGTGCTCATCGTGA
CCGGCGCCGGCCGTGACTTCGCCGCCGGCGCAGACATTGCCGAACTTCGGGTCCGTGGCCGCAACGAAGCACTGGCCGGC
ATCAACCGCACGGTCTTCGACCGGATTGCGGCATTGCCACTGCCGACGATCGCAGCGGTAGAAGGCAATGCTCTCGGCGG
CGGCGCCGAACTGGCCTACGCGTGCGATATCCGGATTGCTGGGGCTGGCGCACGGTTCGGAAATCCGGAACCTGGACTCG
GCATCCTGGCGGCCGCGGGTGCCAGCTACCGGCTGGCCGATCTGGTGGGCAAATCAGTTGCCAAACAAGTGATTCTGGGC
GGCCGGGTGCTCGACGCCGAGGCCGCATTGGCCTGTGGCCTGGTCGCCGAGGTGGTGGCCGAGCACAGCGCGCTGGGTGC
CGCCTCTGCGCTGACCGAGCGCATCACCCGGCAGTCGCCCCTGGCCTTGAGGTTGTCCAAGGCCGTTCTCGACGCCGATT
CCGCGCATCCGCTGATCGATGACCTCGCGCAAGCGGTGCTGTTCGAAAGCCCTGACAAAACCGACCGCATGACGCGATTC
CTCGAAAGGCAGACCAGATGA

Upstream 100 bases:

>100_bases
TCACCTTGCTGAACCGGCTGGAGCGTGAGGGCGCATCTCGCGGGCTGGCGACCTTGTGTGTGGGAGTCGGACAGGGTGTC
GCGATATTGATCGAGGCACC

Downstream 100 bases:

>100_bases
CCGCCACACCCCACAGCGTTCCCACGGTTGTCACCGTGATCGGCGGCGGGCCAATGGGTGCAGGTATAGCGCAGGTGTTC
GCGGCCGCGGGCGCGAATGT

Product: putative enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTEYQTLCVTTEDDRVIVELHRPEQRNAINAAMVADLHAVCATIEAQPRVLIVTGAGRDFAAGADIAELRVRGRNEALAG
INRTVFDRIAALPLPTIAAVEGNALGGGAELAYACDIRIAGAGARFGNPEPGLGILAAAGASYRLADLVGKSVAKQVILG
GRVLDAEAALACGLVAEVVAEHSALGAASALTERITRQSPLALRLSKAVLDADSAHPLIDDLAQAVLFESPDKTDRMTRF
LERQTR

Sequences:

>Translated_246_residues
MTEYQTLCVTTEDDRVIVELHRPEQRNAINAAMVADLHAVCATIEAQPRVLIVTGAGRDFAAGADIAELRVRGRNEALAG
INRTVFDRIAALPLPTIAAVEGNALGGGAELAYACDIRIAGAGARFGNPEPGLGILAAAGASYRLADLVGKSVAKQVILG
GRVLDAEAALACGLVAEVVAEHSALGAASALTERITRQSPLALRLSKAVLDADSAHPLIDDLAQAVLFESPDKTDRMTRF
LERQTR
>Mature_245_residues
TEYQTLCVTTEDDRVIVELHRPEQRNAINAAMVADLHAVCATIEAQPRVLIVTGAGRDFAAGADIAELRVRGRNEALAGI
NRTVFDRIAALPLPTIAAVEGNALGGGAELAYACDIRIAGAGARFGNPEPGLGILAAAGASYRLADLVGKSVAKQVILGG
RVLDAEAALACGLVAEVVAEHSALGAASALTERITRQSPLALRLSKAVLDADSAHPLIDDLAQAVLFESPDKTDRMTRFL
ERQTR

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=235, Percent_Identity=31.4893617021277, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI70995211, Length=237, Percent_Identity=31.2236286919831, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI213417737, Length=208, Percent_Identity=30.7692307692308, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI157694516, Length=208, Percent_Identity=30.7692307692308, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI4502327, Length=243, Percent_Identity=32.0987654320988, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI157694520, Length=166, Percent_Identity=32.5301204819277, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI45643119, Length=218, Percent_Identity=27.5229357798165, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI260275230, Length=218, Percent_Identity=27.5229357798165, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI260274832, Length=218, Percent_Identity=27.5229357798165, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI68989263, Length=181, Percent_Identity=33.7016574585635, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI20127408, Length=175, Percent_Identity=29.1428571428571, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI31542718, Length=169, Percent_Identity=28.9940828402367, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787659, Length=246, Percent_Identity=36.1788617886179, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI221142681, Length=226, Percent_Identity=31.858407079646, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790281, Length=202, Percent_Identity=36.1386138613861, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788682, Length=214, Percent_Identity=34.5794392523364, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788597, Length=207, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI87082183, Length=256, Percent_Identity=25.390625, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787660, Length=211, Percent_Identity=31.2796208530806, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=247, Percent_Identity=33.1983805668016, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI25145438, Length=235, Percent_Identity=34.0425531914894, Blast_Score=116, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17540714, Length=212, Percent_Identity=31.6037735849057, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17536985, Length=225, Percent_Identity=28.8888888888889, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17534483, Length=226, Percent_Identity=28.3185840707965, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17549921, Length=202, Percent_Identity=24.2574257425743, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17540306, Length=199, Percent_Identity=28.1407035175879, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI25144276, Length=180, Percent_Identity=30.5555555555556, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508953, Length=234, Percent_Identity=28.2051282051282, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508951, Length=234, Percent_Identity=28.2051282051282, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17558304, Length=180, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560910, Length=193, Percent_Identity=26.4248704663212, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI20129971, Length=250, Percent_Identity=33.6, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24653477, Length=250, Percent_Identity=33.6, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24653139, Length=242, Percent_Identity=30.5785123966942, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920382, Length=226, Percent_Identity=30.5309734513274, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24650670, Length=219, Percent_Identity=31.5068493150685, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI19921018, Length=222, Percent_Identity=28.8288288288288, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357171, Length=193, Percent_Identity=27.979274611399, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28571730, Length=146, Percent_Identity=29.4520547945205, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571729, Length=146, Percent_Identity=29.4520547945205, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 25768; Mature: 25637

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEYQTLCVTTEDDRVIVELHRPEQRNAINAAMVADLHAVCATIEAQPRVLIVTGAGRDF
CCCCEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
AAGADIAELRVRGRNEALAGINRTVFDRIAALPLPTIAAVEGNALGGGAELAYACDIRIA
CCCCCHHHHEECCCCHHHHHCHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEEEEEEE
GAGARFGNPEPGLGILAAAGASYRLADLVGKSVAKQVILGGRVLDAEAALACGLVAEVVA
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHH
EHSALGAASALTERITRQSPLALRLSKAVLDADSAHPLIDDLAQAVLFESPDKTDRMTRF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
LERQTR
HHHHCC
>Mature Secondary Structure 
TEYQTLCVTTEDDRVIVELHRPEQRNAINAAMVADLHAVCATIEAQPRVLIVTGAGRDF
CCCEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
AAGADIAELRVRGRNEALAGINRTVFDRIAALPLPTIAAVEGNALGGGAELAYACDIRIA
CCCCCHHHHEECCCCHHHHHCHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEEEEEEE
GAGARFGNPEPGLGILAAAGASYRLADLVGKSVAKQVILGGRVLDAEAALACGLVAEVVA
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHH
EHSALGAASALTERITRQSPLALRLSKAVLDADSAHPLIDDLAQAVLFESPDKTDRMTRF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
LERQTR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]