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The map label for this gene is bglP [H]

Identifier: 169833006

GI number: 169833006

Start: 618414

End: 620252

Strand: Direct

Name: bglP [H]

Synonym: SPH_0675

Alternate gene names: 169833006

Gene position: 618414-620252 (Clockwise)

Preceding gene: 169833306

Following gene: 169833680

Centisome position: 27.54

GC content: 34.42

Gene sequence:

>1839_bases
ATGAGTTATAAAGATAAGGTACAAAAAATCCTCGATGTAATTGGAGGTGAAAAAAATGTCAATAGAGTTACCCATTGTGT
AACACGTTTAAGATTAGAATTAAAAGATGAAAATTTAGTCAATGATGATGATGTGAAGAAGATACCAGGTGTAATAGGTA
TTATGAAAAAGAATGGACAATATCAAATTATACTTGGTAATGATGTAGCTAATTATTATAAAGAATTCGTTAAACTTGGC
AATTTTGAATCCGATTCAGTTGTTCAAGGGCACAAAGGGAATATTTTAGAAAGAATCATTGAGTATATCGCTGGTTCCAT
GACTCCAATCATTCCAGCAATGTTAGGGGGAGGTATGCTGAAAGTCTTGGTAATTATTTTACCAATGCTTGGTATATTGC
AATCAGATTCTCAGACTATTGCTTTTTTGACATTTTTTGGGGATGCTCCATATTATTTCTTACCGCTGTTATTAGCTTAT
TCTGCATCACAAAAATTAAAAGTAACATCTACATTAGCTATGTCTGTAGCAGGTGTACTTCTCCATCCAAATTTTGTTCA
AATGGTGCAATCAGGGAATCCTCTTAGTTTATTTGGTGTACCTGTGACACCAGCTAGTTATGGTTCGTCAGTCGTTCCAA
TTCTTATTATGGTTTGGTTGATGAAATATATTGAAAAAATGATTGCTAAATTAACACCAGCTGTTACTAAGAGTTTTTTG
CAACCTACGCTAGTATTATTAGTATCAAGCTGTATTGCCTTAGTTGTAGTCGGACCTATTGGAGTAATTGTTGGTGAAGG
ATTATCAAATCTAGTTGGGCAAATGTATGGTGTAGCTGGATGGCTTACATTAGCTATTCTTGGTGCTATTATGCCATTTA
TTGTTATGACTGGAATGCATTGGGCTTTTGCACCTATTTTTTTGGCGGCATCTATTGCTACTCCAGACGTATTAATTCTT
CCAGCAATGTTAGGGTCAAACTTAGCTCAAGGGGCTGCTTCGATGGCTGTTGCATTAAAGAGTAAAAATAATAATACAAA
ACAAATTGCTTTTGCAGCAGGTTTCTCAGCCTTACTTGCAGGAATTACCGAACCTGCATTATATGGTGTGACTTTAAAAT
ATAAAAAACCGCTTTATGCAGCTATGATTGGTGGTGGATTAGCGGGATTATTTGCAGGTCTTACTAGTGTTAAAGCGTAT
CTATTTGCTGTCCCATCTTTGATAGCGTTGCCTCAATTTATTTATTCTGATGCACCATCAAATATTGTAAATGCTTTAAT
TGTGGCGGTCATTTCGGTTGTTATTACCTTTGTATTAGCTTATATATTTGGAATCGATGAAGAAGAGAGTTCTAGTAATT
TAGAAGTTGAAGCTGGAGTTTCAAATAAAAAAATGATATTTTCTCCTATATCAGGAGAAATCATTCCGTTAAGCGATGTT
CAGGATAAAACATTTTCAGATAAACTAATTGGAGACGGAGTAGCGATTATCCCAAGTGAAGGTAAGGTTTATGCACCATT
TGATGGGAAAATTACAAATATTTTTCCGACTAAGCACGCAATTGGATTGAAGAGTGATGAGGGTGTTGAGTTACTAATTC
ATATCGGATTAGATACTGTTGAGCTAAAAGGTCAAGGTTTTATTAGTCATGTAGAAGAAGGAGACAGAGTTTTCAAAAAT
CAGTTGATTTTTGAAATGGACTTAAATTTAATCAAGACGAAAGGCTACGAAACAGTTACACCAGTAATTGTAACGAATAC
CAATGATTTTCTAGATGTATTAGTATTACCTAATAATCAGACAATCGAGCATTCTAAGGAACTACTGGTAATATTATAA

Upstream 100 bases:

>100_bases
CTGAGTACAATTATTTGCTGACTTCTAGTGAATTAGTTTATTTGATGGCTCATATTCGTCGCTTAACAAAAAATTTAGAT
TAATAGAATAGGAGAATACC

Downstream 100 bases:

>100_bases
TGGAGGAAAGTTATGACCATTTTTCCAGATGATTTTCTTTGGGGTGGAGCTGTTGCAGCTAATCAAGTAGAGGGAGCATA
TAATGAAGATGGTAAGGGCT

Product: phosphotransferase system sugar-specific EII component

Products: NA

Alternate protein names: EIIBCA-Bgl; EII-Bgl; Beta-glucoside-specific phosphotransferase enzyme IIB component; PTS system beta-glucoside-specific EIIB component; Beta-glucoside permease IIC component; PTS system beta-glucoside-specific EIIC component; Beta-glucoside-specific phosphotransferase enzyme IIA component; PTS system beta-glucoside-specific EIIA component [H]

Number of amino acids: Translated: 612; Mature: 611

Protein sequence:

>612_residues
MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDDVKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLG
NFESDSVVQGHKGNILERIIEYIAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMVWLMKYIEKMIAKLTPAVTKSFL
QPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMYGVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLIL
PAMLGSNLAQGAASMAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFAGLTSVKAY
LFAVPSLIALPQFIYSDAPSNIVNALIVAVISVVITFVLAYIFGIDEEESSSNLEVEAGVSNKKMIFSPISGEIIPLSDV
QDKTFSDKLIGDGVAIIPSEGKVYAPFDGKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKN
QLIFEMDLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL

Sequences:

>Translated_612_residues
MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDDVKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLG
NFESDSVVQGHKGNILERIIEYIAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMVWLMKYIEKMIAKLTPAVTKSFL
QPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMYGVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLIL
PAMLGSNLAQGAASMAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFAGLTSVKAY
LFAVPSLIALPQFIYSDAPSNIVNALIVAVISVVITFVLAYIFGIDEEESSSNLEVEAGVSNKKMIFSPISGEIIPLSDV
QDKTFSDKLIGDGVAIIPSEGKVYAPFDGKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKN
QLIFEMDLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL
>Mature_611_residues
SYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDDVKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGN
FESDSVVQGHKGNILERIIEYIAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAYS
ASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMVWLMKYIEKMIAKLTPAVTKSFLQ
PTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMYGVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILP
AMLGSNLAQGAASMAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFAGLTSVKAYL
FAVPSLIALPQFIYSDAPSNIVNALIVAVISVVITFVLAYIFGIDEEESSSNLEVEAGVSNKKMIFSPISGEIIPLSDVQ
DKTFSDKLIGDGVAIIPSEGKVYAPFDGKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQ
LIFEMDLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790159, Length=603, Percent_Identity=33.167495854063, Blast_Score=340, Evalue=2e-94,
Organism=Escherichia coli, GI48994906, Length=465, Percent_Identity=38.494623655914, Blast_Score=339, Evalue=4e-94,
Organism=Escherichia coli, GI2367362, Length=420, Percent_Identity=28.3333333333333, Blast_Score=179, Evalue=6e-46,
Organism=Escherichia coli, GI1788757, Length=137, Percent_Identity=45.2554744525547, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1788769, Length=466, Percent_Identity=24.0343347639485, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786894, Length=128, Percent_Identity=40.625, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011297 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 65757; Mature: 65625

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDDVKKIPGVIGIMKKNGQ
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEEECCCC
YQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEYIAGSMTPIIPAMLGGGML
EEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCHHH
KVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAYSASQKLKVTSTLAMSVAGVL
HHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHH
LHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMVWLMKYIEKMIAKLTPAVTKSFL
CCCHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
QPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMYGVAGWLTLAILGAIMPFIVMTGMH
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
WAFAPIFLAASIATPDVLILPAMLGSNLAQGAASMAVALKSKNNNTKQIAFAAGFSALLA
HHHHHHHHHHHCCCCCCEEHHHHHCCHHHHHHHHHEEEEECCCCCCEEEEEHHHHHHHHH
GITEPALYGVTLKYKKPLYAAMIGGGLAGLFAGLTSVKAYLFAVPSLIALPQFIYSDAPS
HCCCCHHEEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
NIVNALIVAVISVVITFVLAYIFGIDEEESSSNLEVEAGVSNKKMIFSPISGEIIPLSDV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEECCCCCEEECCCC
QDKTFSDKLIGDGVAIIPSEGKVYAPFDGKITNIFPTKHAIGLKSDEGVELLIHIGLDTV
CCCCCCHHHHCCCEEEEECCCCEECCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCEE
ELKGQGFISHVEEGDRVFKNQLIFEMDLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQ
EECCCCHHHHHHHHHHHHHHHEEEEECCHHEECCCCCEECCEEEECCCCEEEEEECCCCC
TIEHSKELLVIL
CCCCCCCEEEEC
>Mature Secondary Structure 
SYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDDVKKIPGVIGIMKKNGQ
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCEEEEECCCC
YQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEYIAGSMTPIIPAMLGGGML
EEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCHHH
KVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAYSASQKLKVTSTLAMSVAGVL
HHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHH
LHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMVWLMKYIEKMIAKLTPAVTKSFL
CCCHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
QPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMYGVAGWLTLAILGAIMPFIVMTGMH
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
WAFAPIFLAASIATPDVLILPAMLGSNLAQGAASMAVALKSKNNNTKQIAFAAGFSALLA
HHHHHHHHHHHCCCCCCEEHHHHHCCHHHHHHHHHEEEEECCCCCCEEEEEHHHHHHHHH
GITEPALYGVTLKYKKPLYAAMIGGGLAGLFAGLTSVKAYLFAVPSLIALPQFIYSDAPS
HCCCCHHEEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
NIVNALIVAVISVVITFVLAYIFGIDEEESSSNLEVEAGVSNKKMIFSPISGEIIPLSDV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEECCCCCEEECCCC
QDKTFSDKLIGDGVAIIPSEGKVYAPFDGKITNIFPTKHAIGLKSDEGVELLIHIGLDTV
CCCCCCHHHHCCCEEEEECCCCEECCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCEE
ELKGQGFISHVEEGDRVFKNQLIFEMDLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQ
EECCCCHHHHHHHHHHHHHHHEEEEECCHHEECCCCCEECCEEEECCCCEEEEEECCCCC
TIEHSKELLVIL
CCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377; 8628237 [H]