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The map label for this gene is pyrI [H]

Identifier: 169824418

GI number: 169824418

Start: 783521

End: 783949

Strand: Direct

Name: pyrI [H]

Synonym: FMG_0721

Alternate gene names: 169824418

Gene position: 783521-783949 (Clockwise)

Preceding gene: 169824417

Following gene: 169824419

Centisome position: 43.59

GC content: 25.17

Gene sequence:

>429_bases
ATGTTAAACATTAATAGTATTGAAAAAGGTATTGTAATTGATCATATTAAATGTGGAATGGGATATAAAATATTTCAACT
TTTAAAGTTAGATAAAGCGGATTATACAGTAGCATTAATTATGAATGCGCAATCAGGTAAACTAGGAAGAAAAGACATGA
TAAAAATCGAAAATGTTATTGATATAGACTTCGATATACTTGGTGTATTTGATGATAATATGACTGTTAATGTAATTGAA
AATGAAAAAATAAAAGAAAAAATCAACTTAAATTTACCAGAACATTTTGAAGGTTTTATTAAATGTAAAAATCCTAGATG
TATAACTCAATCTGAACGTAGTATTGTACAAAAATTTAGCCTAGTAGATAAGGACACTAGAACATATAAATGTGATTATT
GTGATCATCTATATAATGTGGAGGAATAA

Upstream 100 bases:

>100_bases
CTGAAGTTGATAGCGATCCAAGGGCCGTTTATTTCAAACAAGTTAGATACGGCGTAATTGTTAGAATGGCATTAATATTA
AAATTATTAGGGGTGAGATA

Downstream 100 bases:

>100_bases
TGAAATTACTGCTTAAAAATTGTCATATCATAGATAGAGATAAAGATATTTTTGCTGATATTTTAATAGAAAACGCTAAA
ATAAAAGCTATAGGACAAAT

Product: aspartate carbamoyltransferase regulatory subunit

Products: phosphate; N-carbamoyl-L-aspartate

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MLNINSIEKGIVIDHIKCGMGYKIFQLLKLDKADYTVALIMNAQSGKLGRKDMIKIENVIDIDFDILGVFDDNMTVNVIE
NEKIKEKINLNLPEHFEGFIKCKNPRCITQSERSIVQKFSLVDKDTRTYKCDYCDHLYNVEE

Sequences:

>Translated_142_residues
MLNINSIEKGIVIDHIKCGMGYKIFQLLKLDKADYTVALIMNAQSGKLGRKDMIKIENVIDIDFDILGVFDDNMTVNVIE
NEKIKEKINLNLPEHFEGFIKCKNPRCITQSERSIVQKFSLVDKDTRTYKCDYCDHLYNVEE
>Mature_142_residues
MLNINSIEKGIVIDHIKCGMGYKIFQLLKLDKADYTVALIMNAQSGKLGRKDMIKIENVIDIDFDILGVFDDNMTVNVIE
NEKIKEKINLNLPEHFEGFIKCKNPRCITQSERSIVQKFSLVDKDTRTYKCDYCDHLYNVEE

Specific function: Involved in allosteric regulation of aspartate carbamoyltransferase [H]

COG id: COG1781

COG function: function code F; Aspartate carbamoyltransferase, regulatory subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyrI family [H]

Homologues:

Organism=Escherichia coli, GI1790692, Length=137, Percent_Identity=34.3065693430657, Blast_Score=89, Evalue=8e-20,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 440 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020545
- InterPro:   IPR002801
- InterPro:   IPR020542
- ProDom:   PD006194 [H]

Pfam domain/function: PF01948 PyrI; PF02748 PyrI_C [H]

EC number: 2.1.3.2

Molecular weight: Translated: 16452; Mature: 16452

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNINSIEKGIVIDHIKCGMGYKIFQLLKLDKADYTVALIMNAQSGKLGRKDMIKIENVI
CCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCEEECCEE
DIDFDILGVFDDNMTVNVIENEKIKEKINLNLPEHFEGFIKCKNPRCITQSERSIVQKFS
ECCEEEEEEECCCEEEEEECCCCCHHHCCCCCCHHCCEEEEECCCCCCCHHHHHHHHHHH
LVDKDTRTYKCDYCDHLYNVEE
HCCCCCCEEECCCHHHHCCCCC
>Mature Secondary Structure
MLNINSIEKGIVIDHIKCGMGYKIFQLLKLDKADYTVALIMNAQSGKLGRKDMIKIENVI
CCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCEEECCEE
DIDFDILGVFDDNMTVNVIENEKIKEKINLNLPEHFEGFIKCKNPRCITQSERSIVQKFS
ECCEEEEEEECCCEEEEEECCCCCHHHCCCCCCHHCCEEEEECCCCCCCHHHHHHHHHHH
LVDKDTRTYKCDYCDHLYNVEE
HCCCCCCEEECCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: carbamoyl phosphate; L-aspartate

Specific reaction: carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA